PDF Cold Induced Skin Disease

[Pages:29]Cold Induced Skin Diseases

Lynne H Morrison

? Raynaud's phenomenon ? Pernio ? Livedo reticularis ? Cold panniculitis

Raynaud's Phenomenon

? Exaggerated response of digital arterial circulation to cold ? Episodic with sharply demarcated triphasic color change of digits

? Blanching/pallor from arterial vasoconstriction ? Cyanosis from sluggish flow of deoxygenated venous blood ? Erythema from reactive hyperemia

? Not all patients have all three phases ? Overall prevalence is 10% ( 3-15%) ? F:M= 4:1

Primary vs Secondary Raynaud's

? Primary Raynaud's Phenomenon

? Raynaud's disease ? No underlying disease association ? Most common form of RP ? Onset ................
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