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Sheila and Alf are planning to have a child, but are concerned about having a child with spinal muscular atrophy. Sheila had a son with a previous partner that died from SMA. Alf has no family history of SMA. The carrier frequency of SMA in the general population is 1 in 50. What is the risk to the couple of having a child affected with SMA? ΒΌ ... ................
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