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Name: ___________________________________________Date: __________ Mod: ______The History of VaccinesPart 1: Opening Activity–Introduce the History of Vaccination Use the internet (use your judgment to determine a websites reliability) to briefly research the following diseasesDiseaseSummary of SymptomsYear of VaccinationMeaslesMumpsPolioTuberculosis2. Are the Measles, Mumps, Polio, or Tuberculosis a major cause of death currently in the United States? Explain.Part 2- After watching the video clip: “Plotkin and the Role of Vaccination,” answer the questions below:. What are the three entities that have had major public health impacts? 4. What made Stanley A. Plotkin, MD, pursue the path of a vaccinologist?Part 3: Explore the contributions of some of the researchers who developed early vaccines, using the History of Vaccines timelines. You can access the information by clicking TIMELINES in the main navigation bar and then clicking Pioneers.. Click on Diseases and Vaccines and choose one of the diseases. Read through each of the events and create a timeline below including the ten biggest events. (Your timeline should be a single straight line with equal increments dividing the time between the first and last event. Each event should be identified with a dot on the timeline with a line connecting to a brief description.)Part 4- Article: The Scientific Method in Vaccine History. Read the article and answer the questions below. . Why is there no single model of the scientific method? 7. Do scientists try to prove their ideas by using the scientific method? Explain. 8. What are the four main steps of the scientific method? a. b. c. d. 9. What are the qualities of a good hypothesis? a. b. c. d. 10. What three types of scientific studies? a. b. c. 11. What is the difference between the experimental group and the control group in an investigation? 12. How did Edward Jenner test the observation of a milkmaid that having cowpox protected a person from the deadly disease smallpox? 13. What was Robert Koch’s method of identifying the cause of a disease? 14. What was Pearl Kendrick’s contribution to the development of a scientific method for testing vaccines? 15. How did Jonas Salk’s method of testing his polio vaccine improve the way new vaccines are tested?Part 5- Scientific Method Simulation. Complete the questions below while you complete the simulation. . What problem will you be investigating with the scientific method? 17. What can cause the data an investigator collects to be compromised, or invalid? Observation 18. Which of the four reports describe an illness that could be traced to a likely cause? Explain. 19. What were some similarities in the information contained in the other three reports? 20. What three steps did you take in gathering information about each case? a. b. c. 21. Why did the expert recommend the use of the fastest methods for investigating the three cases? 22. What patterns were uncovered in the initial investigation? Hypothesis 23. What qualities did the expert say that good hypotheses for this investigation should have? 24. What two possible causes of the outbreak did you choose to explore? 25. Why were the other two proposed diseases discarded as possible causes? Why? 26. Which hypothesis did you decide to investigate first? Why? Testing & Experimentation 27. What laboratory tests are used to identify the pathogen in a disease outbreak? 28. Which test was chosen as the best one to use? Why? 29. What is the name for the study of how a disease spreads? 30. What are the two main methods used to study how a disease spreads? 31. Which tool of epidemiology uses case histories of a control group, as well? 32. What were the results of the tests conducted? 33. In which group were case histories and rapid PCR tests not performed? How are these cases being treated? 34. What was causing the illness among recruits and at the senior center? Analysis & Conclusions 35. What did the odds ratios show about the spread of the disease among the affected groups? 36. What was the “unexpected finding” in the data? 37. What should you look for when you have an unexpected finding? 38. What was the cause of error in this investigation? ................
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