Tetrahedron template - Imperial College London
Bu solid-phase peptide synthesis (SPPS), and the warhead moiety coupled directly to the N-terminal amine prior to cleavage from the resin as a C-terminal PEG-Biotin conjugate. N-terminal chloroacetamide (CAA), fluoroacetamide (FAA) and Michael acceptor (MA) probes were readily synthesized in acceptable overall yields, with a range of ... ................
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