Possible Side Effects of Cytarabine (ara-c), Daunorubicin ...



Possible Side Effects of Cytarabine (ara-c), Daunorubicin, IT Methotrexate, PEG L-asparaginase, Prednisone, Vincristine (Table Version Date: August 28, 2014)

|COMMON, SOME MAY BE SERIOUS |

|In 100 people receiving Cytarabine (ara-c), Daunorubicin, IT Methotrexate, PEG L-asparaginase, Prednisone, Vincristine, more than 20 and up to 100 may have: |

|Blood clot |

|Rash, hives |

|Swelling in the rectum which may cause rectal pain |

|Diarrhea, constipation, loss of appetite, nausea, vomiting |

|Sores in mouth which may cause difficulty swallowing |

|Anemia which may cause tiredness, or may require blood transfusions |

|Fever, chills |

|Hair loss |

|Pink or red colored urine, sweat, or saliva |

|Pain, swelling and redness at the site of injection |

|Numbness and tingling of fingers or toes |

|Headache, jaw pain and/or muscle pain |

|Weakness and difficulty walking |

|Swelling of the body |

|In children and adolescents: decreased height |

|Loss of bone tissue |

|Mood swings, tiredness |

|Skin changes, acne |

|High blood pressure which may cause headaches, dizziness, blurred vision |

|Pain |

|Increased appetite and weight gain |

|Weight gain in the belly, face, back and shoulders |

|Allergic reaction which may cause rash, low blood pressure, wheezing, shortness of breath, swelling of the face or throat |

|OCCASIONAL, SOME MAY BE SERIOUS |

|In 100 people receiving Cytarabine (ara-c), Daunorubicin, IT Methotrexate, PEG L-asparaginase, Prednisone, Vincristine, from 4 to 20 may have: |

|Infection, especially when white blood cell count is low |

|Bruising, bleeding |

|Numbness and tingling of the arms and legs |

|Severe blood infection |

|Liver damage which may cause yellowing of skin or eyes |

|Swelling and redness of the eye, drooping eyelids |

|Damage to the heart which may cause shortness of breath, tiredness |

|Abnormal heart beat |

|Chest pain |

|Dark discoloration of the nail, skin |

|Loss of nails |

|Cloudiness of the eye, visual disturbances |

|Glaucoma |

|Redness and pain at the site of previous radiation |

|Cancer of the bone marrow (leukemia) cause by chemotherapy |

|Hoarseness |

|Non-healing wound |

|Diabetes |

|Damage to the bone which may cause joint pain and loss of motion |

|Kidney stones |

|Heartburn |

|Night sweats |

|RARE, AND SERIOUS |

|In 100 people receiving Cytarabine (ara-c), Daunorubicin, IT Methotrexate, PEG L-asparaginase, Prednisone, Vincristine, 3 or fewer may have: |

|Seizure |

|Bleeding from sores in the stomach |

|Broken bones |

|Damage to the pancreas |

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