Behçet’s Disease



|Behçet’s Disease |Systemic vasculitis associated with HLA-B51. Recurrent oral & genital ulceration,|

| |ocular inflammation, skin lesions, neurological problems & joint problems |

|Berger’s Disease |IgA nephropathy. Commonest cause of glomerulonephritis. Episodic haematuria. May |

| |be secondary to alcoholism, ankylosing spondylitis, celiac disease or HIV |

|Brown-Séquard Syndrome |A lesion of one half of the cord. Ipsilateral UMN weakness & brisk reflexes below|

| |lesion. Ipsilateral loss of proprioception & vibration (dorsal columns). |

| |Contralateral loss of pain & temperature |

|Budd-Chiari Syndrome |Hepatic vein obstruction (by thrombus or tumour) leads to ischaemic hepatocyte |

| |damage. Abdo pain, hepatomegaly, ascites, ↑ALT & portal hypertension |

|Buerger’s Disease |Inflammation of arteries and veins and thrombosis of middle-sized arteries. May |

| |lead to gangrene |

|Caplan’s Syndrome |Multiple lung nodules in coal workers with RA, caused by an inflammatory reaction|

| |to external allergen |

|Charcot-Marie-Tooth Syndrome |Peroneal muscular atrophy. Inherited neuropathy. Starts in puberty with weak legs|

| |and foot drop |

|Churg-Strauss Syndrome |Asthma |

| |Eosinophilia |

| |Vasculitis (affecting lungs, nerves & skin) |

|Dressler’s Syndrome |Myocardial autoantibodies following MI. Recurrent chest pain and fever post-MI. |

| |May lead to cardiac tamponade |

|Dubin-Johnson Syndrome |Autosomal Recessive. Defective hepatocyte ecretion of conjugated bilirubin. |

| |Intermittent jaundice and RUQ pain |

|Fanconi Anaemia |Autosomal recessive disorder with defective stem cell repair, leading to aplastic|

| |anaemia, skin pigmentation, skeletal malformation & neuro deficits |

|Felty’s Syndrome |Rheumatoid Arthritis (Rh factor ↑↑) |

| |Splenomegaly |

| |Low WCC |

|Friedreich’s Ataxia |Autosomal recessive disorder. Degeneration of multiple nerve tracts |

|Gardner’s Syndrome |Variant of FAP. Multiple malignant colon polyps. Black spots on fundoscopy |

|Gilbert’s Syndrome |Inherited unconjugated hyperbilirubinaemia. Benign condition |

|Goodpasture’s Syndrome |Acute glomerulonephritis & lung symptoms caused by anti-basement membrane |

| |antibodies |

|Guillain-Barré Syndrome |Symmetrical ascending muscle weakness. May occur post flu-vaccination, |

| |gastroenteritis or URTI |

|Henoch-Schönlein Purpura |Small vessel vasculitis and IgA nephropathy |

|Horner’s Syndrome |Miosis, enopthalmos, ptosis and anhidrosis due to interruption of the face’s |

| |sympathetic supply |

|Kaposi’s Sarcoma |Tumour derived from capillary endothelial cells or from fibrous tissue. |

| |Associated with herpes |

|Korsakoff’s Syndrome |Inability to lay down new memories, especially in alcoholics, due to thiamine |

| |deficiency |

|Leriche’s Syndrome |Absent femoral pulses, intermittent claudication of buttock muscles, pale cold |

| |legs and erectile dysfunction due to aortic occlusive disease |

|Meig’s Syndrome |Pleural effusion (transudative) and benign ovarian fibroma and ascites |

|Millroy’s Syndrome |Inherited lymphatic problem leading to asymmetrical leg swelling |

|Nelson’s Syndrome |Increased skin pigmentation due to excess ACTH from an enlarging pituitary tumour|

| |following bilateral adrenalectomy |

|Osler-Weber-Rendu Syndrome |Hereditary haemorrhagic telangectasia. May cause chronic GI bleeds and Fe |

| |deficient anaemia. Autosomal Dominant |

|Pancoast’s Syndrome |Apical lung cancer and ipsilateral Horner’s syndrome |

|Peutz-Jegher’s Syndrome |Mucocutaneous dark freckles on lips, oral mucosa, palm and soles +/- GI polyps |

|Pott’s Syndrome |Spinal TB |

|Romano-Ward Syndrome |Mutation in K+ channel subunit leading to congenital long QT segment. Increased |

| |risk of VT, syncope and sudden death |

|Stevens-Johnson Syndrome |Severe form of erythema multiforme and toxic epidermal necrolysis. |

| |Hypersensitivity reaction to drugs, eg salicylates) |

|Sturge-Weber Syndrome |Facial port-wine stain on face with contralateral focal fits due to a |

| |corresponding haemangioma in the brain |

|Tietze’s Syndrome |Idiopathic costochondritis, enhanced by coughing and sneezing. 2nd rib is most |

| |commonly affected |

|Todd’s Palsy |Stroke-like symptoms following a seizure. Resolves within 24 hours |

|Von Hippel-Lindau Syndrome |Mutation of tumour suppressor gene leading to predisposition to bilateral renal |

| |carcinoma and retinal/cerebellar haemangioblastoma and phaeochromocytoma |

|Weber’s Syndrome |Ipsilateral 3rd nerve palsy with contralateral hemiplegia due to infarction of |

| |one half of the midbrain |

|Wegener’s Granulomatosis |Vasculitis of small and medium vessels. Esp URTI, lungs and kidney |

|Zollinger-Ellison Syndrome |Pancreatic tumour which secretes gastrin, thereby leading to peptic ulceration |

................
................

In order to avoid copyright disputes, this page is only a partial summary.

Google Online Preview   Download