Biochemistry Objectives 46
TRH: Thyroid releasing hormone stimulates thyrotrophic release of TSH via Gq and the IP3/DAG/Ca2+ pathway. TSH: thyroid stimulating hormone T4 activation to T3 in peripheral target cells: T4 is brought into the cell by passive diffusion when bound to TBG, and is converted to the more metabolically active T3 form by 5’ deiodinase. ................
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