GEORGIA BAPTIST COLLEGE OF NURSING
GEORGIA BAPTIST COLLEGE OF NURSING
OF
MERCER UNIVERSITY
NUR 312 Pharmacology in Nursing II
Unit IV: Drugs That Affect Fluid-Gas Transport:
Coagulation:
Anticoagulants and Coagulants
Lesson Objectives: At the completion of this lesson, the student will:
1. Relate the basic concepts of hemostasis and fibrinolysis to drug therapy.
2. Distinguish among specific anticoagulant agents in relation to
pharmacodynamics, pharmacokinetics, and side effects and rationale
for use.
3. Describe clinical manifestations as related to anticoagulant and coagulant
therapy.
4. Discuss education necessary for individuals on coagulant therapy.
5. Utilize the nursing process to identify specific nursing considerations for
individuals receiving agents that affect coagulation.
Content Outline:
1. Review of coagulation physiology
2. Anticoagulants: Dynamics/Kinetics, Therapeutics, Side Effects/Adverse
Reactions, and Nursing Considerations
1. Indications and contraindications related to use
2. heparin (Canadian: Hepalean)
3. enoxaprin (Lovenox)
2.4. warfarin sodium (Coumadin)
3. Antiplatelets
1. ticlopidine (Ticlid)
2. salicylates- acetylsalicylic acid (Aspirin)
3. Anticoagulant antagonists: Dynamics, Therapeutics, Side Effects/Adverse
Reactions, and Nursing Considerations
1. protamine sulfate
2. vitamin K (Aquamephyton)
4. Coagulants: Dynamics/Kinetics, Side Effects/Adverse Reactions, and
Nursing Considerations
1. Plasma products
1. antihemophilic factor VIII (Monoclate)
2. factor IX Complex (Konyme)
2. Enzyme Inhibitor - aminocaporic acid (Amicar)
3. Topical hemostatic agents
1. oxidized cellulose (Surgicel)
2. gelatin (Gelfoam)
5. Thrombolytic agents: Dynamics/Kinetics, Side Effects/Adverse Reactions,
and Nursing Considerations
1. streptokinase (Streptase)
Teaching/Learning Activities:
1. Lecture/discussion
2. Handouts
3. Selected media
Critical Thinking Focus:
Drug correlation assignment and review of case studies.
Required Reading:
Aschenbrenner, D. S., Cleveland, L., & Venable, L. J., & (2002). Drug therapy
in nursing. (pp. 553-582). Philadelphia: Lippincott.
Anticoagulants
Revised:; 5/01 EL; 12/01 EL.5/02 BR
11/02LC. 7/03/LC;05/04/BBR;05/05/BBR
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