GEORGIA BAPTIST COLLEGE OF NURSING



GEORGIA BAPTIST COLLEGE OF NURSING

OF

MERCER UNIVERSITY

NUR 312 Pharmacology in Nursing II

Unit IV: Drugs That Affect Fluid-Gas Transport:

Coagulation:

Anticoagulants and Coagulants

Lesson Objectives: At the completion of this lesson, the student will:

1. Relate the basic concepts of hemostasis and fibrinolysis to drug therapy.

2. Distinguish among specific anticoagulant agents in relation to

pharmacodynamics, pharmacokinetics, and side effects and rationale

for use.

3. Describe clinical manifestations as related to anticoagulant and coagulant

therapy.

4. Discuss education necessary for individuals on coagulant therapy.

5. Utilize the nursing process to identify specific nursing considerations for

individuals receiving agents that affect coagulation.

Content Outline:

1. Review of coagulation physiology

2. Anticoagulants: Dynamics/Kinetics, Therapeutics, Side Effects/Adverse

Reactions, and Nursing Considerations

1. Indications and contraindications related to use

2. heparin (Canadian: Hepalean)

3. enoxaprin (Lovenox)

2.4. warfarin sodium (Coumadin)

3. Antiplatelets

1. ticlopidine (Ticlid)

2. salicylates- acetylsalicylic acid (Aspirin)

3. Anticoagulant antagonists: Dynamics, Therapeutics, Side Effects/Adverse

Reactions, and Nursing Considerations

1. protamine sulfate

2. vitamin K (Aquamephyton)

4. Coagulants: Dynamics/Kinetics, Side Effects/Adverse Reactions, and

Nursing Considerations

1. Plasma products

1. antihemophilic factor VIII (Monoclate)

2. factor IX Complex (Konyme)

2. Enzyme Inhibitor - aminocaporic acid (Amicar)

3. Topical hemostatic agents

1. oxidized cellulose (Surgicel)

2. gelatin (Gelfoam)

5. Thrombolytic agents: Dynamics/Kinetics, Side Effects/Adverse Reactions,

and Nursing Considerations

1. streptokinase (Streptase)

Teaching/Learning Activities:

1. Lecture/discussion

2. Handouts

3. Selected media

Critical Thinking Focus:

Drug correlation assignment and review of case studies.

Required Reading:

Aschenbrenner, D. S., Cleveland, L., & Venable, L. J., & (2002). Drug therapy

in nursing. (pp. 553-582). Philadelphia: Lippincott.

Anticoagulants

Revised:; 5/01 EL; 12/01 EL.5/02 BR

11/02LC. 7/03/LC;05/04/BBR;05/05/BBR

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