The Skin

LUPUS. Ultraviolet B generates Type 1 Interferon and induces autoantibody-mediated disease in a mouse model of cutaneous lupus. Sontheimer , Clayton, Elkon , Keith. Background/Purpose: Photosensitivity is a common symptom in patients with systemic lupus erythematosus (SLE) and lupus skin lesions often contain plasmacytoid dendritic cells (pDC). ................
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