SFig .gov
SFig.1
FITC-Lamp1
Control
Fas L
TRITC-CTXB
Overlay
Relative Sortilin mRNA Level
A 1.5
1.2
#
0.9
0.6
0.3
*
0.0
Ctrl
B
Ctrl
Scra
siRNA
SiRNA
sortilin
45KD
¦Â-actin
C
1.5
#
1.2
0.9
0.6
0.3
0.0
D
Scra
100KD
Expression of Sortilin
(Normalized to ¦Â-actin )
SFig.2
Control
*
Ctrl
Scra
FITC-sRNA
siRNA
EC(-)
SFig.3
A
0min
5min
10min
15min
20min
B
FITC-Lamp1 TRITC-Anti-IgG
Overlay
FITC-Lamp1
TRITC-Anti-IgG
Pre-
Post-
bleached
FRET
bleached
GPN(-)
bleached
bleached
200 ?M GPN
Overlay
SFig.4
FITC-Lamp1
AM1-43
Overlay
................
................
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