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heart that has an increased demand for O2; the same is true in pressure overload, such as in aortic stenosis or arterial hypertension; in these cases, the pressure overload triggers remodeling, and as stated above, “a remodeled heart” has an increased O2 demand; the same is true in left-to-right shunts and regurgitant valvular lesions that result in volume overload; just like myocardial ... ................
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