UNIVERSITY OF WASHINGTON
UNIVERSITY OF WASHINGTON September 26, 2005
SCHOOL OF MEDICINE CURRICULUM VITAE
Lucas R. Hoffman, MD, PhD
1. Personal Data: Born January 12, 1968 in Cambridge, Massachusetts.
2. Education:
|INSTITUTION AND LOCATION |DEGREE |YEAR(s) |FIELD OF STUDY |
|University of California, Berkeley |BS |1990 |Chemistry |
|College of Chemistry | | | |
|Berkeley, CA | | | |
|University of California, San Francisco |PhD |1996 |Biochemistry |
|Department of Biochemistry | | | |
|San Francisco, CA | | | |
|University of California, San Francisco |MD |1998 |Medicine |
|School of Medicine | | | |
|San Francisco, CA | | | |
3. Postgraduate Training:
2001-2005 Fellowship in Pediatric Pulmonology, Children’s Hospital
and Regional Medical Center, Seattle, WA
1998-2001 Residency in Pediatrics, Children's Hospital and Regional
Medical Center, Seattle, WA
4. Faculty Positions Held:
2005-present Acting Assistant Professor in Pediatrics, Children’s Hospital and
Regional Medical Center, Seattle, WA
2004-present Acting Instructor in Pediatrics, Children’s Hospital and
Regional Medical Center, Seattle, WA
5. Hospital Positions Held: None.
6. Honors:
2004-2005 Leroy Matthews Physician Scientist Award
2004 Children’s Hospital and Regional Medical Center Fellows Research Day Presentation Award
2003-2004 Cystic Fibrosis Foundation Third-year Research Fellowship Training Award
2002-2003 Cystic Fibrosis Foundation Clinical Fellowship Second-year Training Award
2001-2002 Cystic Fibrosis Foundation Clinical Fellowship First-year Training Award
1996. Young Scientist Award for the meeting Options for the Control of Influenza III, Cairns, Australia
1994. Richard Fineberg Memorial Student Teaching Award, UCSF
1990-1998 Medical Scientist Training Program Award
1990 University Citation, UC Berkeley (One of top 10 Univ. grads)
Departmental Citation (valedictorian), College of Chemistry,
UC Berkeley
Invited graduation speaker
1988-1990 Thompson Chemistry Scholarship
Howard Chemistry Scholarship
1988 Phi Beta Kappa (Junior year)
1986-1990 Regents' Scholarship, UC Berkeley
7. Board Certification: American Board of Pediatrics, 2001.
8. Current License(s) to Practice: Washington State full license, number 025209MD00040283 Issued 8/8/01, expires 1/12/06
9. Professional Organizations:
American Academy of Pediatrics
American Association for the Advancement of Science
American College of Chest Physicians
American Thoracic Society
10. Teaching Responsibilities:
2001 Assistant Chief Resident in Pediatrics, Children’s Hospital and Regional Medical Center, Seattle, WA
1994 Teaching assistant for Macromolecular Interactions, Department of Pharmaceutical Chemistry, UCSF
11. Editorial Responsibilities: None.
12. Special National Responsibilities: None
13. Special Local Responsibilities: None.
14. Research Funding:
Mentored Clinical Scientist Development Award (K08)
PI: Lucas Hoffman Sponsor: Samuel I. Miller
Source: NIH, National Institute of Allergy and Infectious Disease
Title: Antibiotic-mediated adaptation of Pseudomonas aeruginosa.
Dates of proposed support: July 15, 2005-May 31, 2008
Annual direct cost: $116,950
Leroy Matthews Physician Scientist (career development) Award
Active: project number HOFFMA04L0
PI: Lucas Hoffman Sponsor: Samuel I. Miller
Source: Cystic Fibrosis Foundation
Title: Alteration of Pseudomonas aeruginosa gene expression by sublethal cationic antibiotic concentrations: Adaptation to the CF airway.
Dates of approval: July 1, 2004- June 30, 2005
Annual direct cost: $67,500
Title: Cystic Fibrosis Foundation Third-year Research Fellowship Training Award
PI: Lucas Hoffman – Sponsor: Samuel Miller
Source: Cystic Fibrosis Foundation
Dates: July 1, 2003 – June 30, 2004
Annual direct costs: $62,600
Title: Cystic Fibrosis Foundation Second-year Research Fellowship Training Award
PI: Lucas Hoffman – Sponsor: Samuel Miller
Source: Cystic Fibrosis Foundation
Dates: July 1, 2002 – June 30, 2003
Annual direct costs: $43,750
Title: Cystic Fibrosis Foundation First Year Research Fellowship Training Award
PI: Lucas Hoffman – Sponsor: Samuel Miller
Source: Cystic Fibrosis Foundation
Dates: July 1, 2001 – June 30, 2002
Annual direct costs: $42,000
15. Research Funding Applications Pending:
Leroy Matthews Physician Scientist (career development) Award Renewal
Project number HOFFMA04L0
PI: Lucas Hoffman Sponsor: Samuel I. Miller
Source: Cystic Fibrosis Foundation
Title: Alteration of Pseudomonas aeruginosa gene expression by sublethal cationic antibiotic concentrations: Adaptation to the CF airway.
Dates of approval: July 1, 2008- June 30, 20010
Annual direct cost: $85,000
16. Bibliography
a) Manuscripts in Refereed Journals
1. Stearns, DM; Hoffman, LR; and Armstrong, WH. Structure of N,N-[Bis(2-pyridylmethyl)-gamma-aminobutyrato]copper (II) Bromide Methanol Solvate. Acta Crystallographica Section C- Crystal Structure Communications, 1992. V48 FEB: 253-256.
2. Hoffman, LR. The Low pH-induced Conformational Change in the Influenza Hemagglutinin: Inhibitor Design. 1996. PhD thesis, UCSF.
3. Hernandez, LD; Hoffman, LR; Wolfsberg, TG; and White, JM. Virus-Cell and Cell-Cell Fusion. Annual Review of Cell and Developmental Biology, 1996. 12:627-661.
4. Hoffman, LR; Kuntz, ID; and White, JM. Structure-based Identification of an Inducer of the Low-pH Conformational Change in the Influenza Hemagglutinin: Irreversible Inhibition of Infectivity. Journal of Virology, 1997. 71(11):8808-8820.
5. Rutenber, EE; De Voss, JJ; Hoffman, LR; Stroud, RM; Lee, KH; Alvarez, J; McPhee, F; Craik, C; and Ortiz de Montellano, PR. The Discovery, Characterization, and Crystallographically Determined Binding Mode of an FMOC Containing Inhibitor of HIV-1 Protease. Bioorganic and Medicinal Chemistry, 1997. 5(7): 1311-1320.
6. Quiao, H; Pelletier, SL; Hoffman, LR; Hacker, J; Armstrong, RT; and White, JM. A Specific Proline Substitution in the Coiled-Coil Region of the Influenza Hemagglutinin Impairs its Membrane Fusion Activity. Journal of Cell Biology, 1998. 141(6):1335-1347.
7. Hoffman LR; D'Argenio DA; MacCoss MJ; Zhang Z; Jones RA; Miller SI; Aminoglycoside Antibiotics Induce Bacterial Biofilm Formation. Nature, 2005. 436(7054):1171-5.
8. Hoffman, LR*; Yen, YH*; Gibson, RL; Van Niel, CW. Lipoid Pneumonia due to Mexican Folk Remedies: Cultural Barriers to Diagnosis. Archives of Pediatrics and Adolescent Medicine, 2005. 159:1043-1048. *These two authors contributed equally.
b) Book chapters
1. White, JM; Hoffman, LR; Arevalo, JH; and Wilson, IA. Attachment and Entry of Influenza Virus into Host Cells: Pivotal Roles of the Hemagglutinin. In: Structural Biology of Viruses, Chiu,W; Burnett, RM; and Garcea, RL; eds. 1997. Oxford Press, New York.
2. Hoffman, LR; White, JM; and Kuntz, ID. Fusion Mechanism of the Influenza Hemagglutinin: Inhibitor Design. In: Options for the Control of Influenza III: Proceedings. Brown, LE; Hampson, AW; and Webster, RG; eds. 1996. Elsevier Science, BV, The Netherlands.
c) Published books, videos, software, etc.
None.
d) Other publications, e.g., in non-refereed journals and letters to the Editor
None.
e) Manuscripts submitted or in press
1. Hoffman, LR; Emerson, J; Gibson, RL; Redding, GJ. Return to Best Spirometric Baseline After Admission for Cystic Fibrosis Pulmonary Exacerbation. Submitted to: American Journal of Respiratory and Critical Care Medicine, April 7, 2004; in revision.
f) Abstracts and posters:
1. Hoffman, LR; Emerson, J; Gibson, RL; Redding, GJ. Frequency of Return to Best PFT Baseline After CF Cleanout: A Pilot Quality Improvement (QI) Project. Presented at: 2003 American Thoracic Society International Conference in Seattle, Washington, May 21, 2003. Am J Resp Crit Care Med, 2003. 167(7): 23.
2. Debley, JS; Hoffman, L; Redding, G. Thoracic Index as a Measure of Hyperinflation during and Following RSV Hospitalization. Presented at: 2003 ATS International Conference in Seattle, Washington, May 19, 2003. Am J Resp Crit Care Med, 2003. 167(7): 507.
3. Hoffman, LR; D’Argenio, D; Jacobs, M; Miller, SI. The response of Pseudomonas aeruginosa to sublethal tobramycin concentrations. Presented at: 2004 Williamsburg Conference on Cystic Fibrosis in Williamsburg, VA, June 6, 2004.
4. Hoffman LR; D’Argenio D; Ernst RK; Miller SI. Effect of the antibiotic tobramycin on biofilm formation by Pseudomonas aeruginosa. Presented at: 2004 Gordon Conference on Bacterial Cell Surfaces in New London, NH, June 28, 2004.
5. Hoffman LR; D'Argenio DA; MacCoss MJ; Zhang Z; Jones RA; Miller SI; Aminoglycoside Antibiotics Induce Bacterial Biofilm Formation. Presented at: 2005 Williamsburg Conference on Cystic Fibrosis in Williamsburg, VA, June 6, 2005.
6. Hoffman LR; D'Argenio DA; MacCoss MJ; Zhang Z; Jones RA; Miller SI; Aminoglycoside Antibiotics Induce Bacterial Biofilm Formation. Presented at: 2005 International Meeting on Pseudomonas in Marseille, France, August 26, 2005.
g) National invitational lectures, etc.
1. Fusion Mechanism of the Influenza Hemagglutinin: Inhibitor Design. At: The World Health Organization: Options for the Control of Influenza III; Cairns, Australia. May 4-9, 1996.
2. Preliminary Structure-based Searches for RSV/HIV Integrase Inhibitors. At: The Tenth Meeting of Groups Studying the Structure of AIDS-related Systems and Their Application to Targeted Drug Design; NIH campus, Bethesda, Maryland. June 25-27, 1996.
3. Case Presentation: Refractory Mycobacterial Pulmonary Infection in a Patient With Cystic Fibrosis. At: Seattle CF Center and Affiliate Centers Annual Clinical Conference, University of Washington, Seattle, Washington. July 19, 2002. And at: The 16th Annual North American CF Conference (NACFC), New Orleans, LA October 4, 2002.
4. Sublethal Tobramycin Concentrations Alter Pseudomonas aeruginosa Virulence and Biofilm Formation. At: Children’s Hospital and Regional Medical Center Fellows’ Research Day. April 20, 2004.
5. Return to Best Spirometric Baseline After Admission for CF Exacerbation. At: Seattle CF Center and Affiliate Centers Annual Clinical Conference, University of Washington, Seattle, Washington. July 15, 2004.
6. Antibiotic Induction of Pseudomonas aeruginosa Biofilm Formation. At: University of Washington Inderdepartmental Microbial Pathogenesis Seminar. December 9, 2004.
Languages Spoken:
16. Fluent in Spanish, working knowledge of Russian and German.
-----------------------
8/26/05 - mzs
................
................
In order to avoid copyright disputes, this page is only a partial summary.
To fulfill the demand for quickly locating and searching documents.
It is intelligent file search solution for home and business.
Related download
- animal communication university of washington
- university of mary washington college of education
- university of washington
- 1 university of washington
- major requirements for ess b university of washington
- proposal to offer a new academic program major
- introduction and brief program description
- statistical genetics certificate program
Related searches
- university of washington hr jobs
- university of washington jobs listing
- university of washington human resources
- university of washington human resources dept
- university of washington baseball roster
- university of washington product management
- university of washington online mba
- university of washington printable map
- university of washington opioid taper
- university of washington opioid calculator
- university of washington program management
- university of washington graduate programs