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Supplementary contentTable S1. Search strings and termsDatabaseSearch queryNumber of found recordsNumber of found records without ('liver transplantation'/exp OR ('liver'/de AND ('transplantation'/de OR 'organ donor'/de OR 'organ transplantation'/de)) OR 'liver donor'/de OR 'liver graft rejection'/de OR (((liver* OR hepatic*) NEAR/6 (transplant* OR homotransplant* OR allotransplant* OR graft* OR homograft* OR allograft* OR donor* OR donation))):ab,ti,kw) AND ('reperfusion'/exp OR 'perfusion'/exp OR 'portal vein blood flow'/exp OR 'blood flow'/de OR 'hepatic portal system'/exp OR 'portal system'/de OR 'hepatic artery'/exp OR 'venous circulation'/exp OR 'circulation'/de OR (reperfusion* OR perfusion* OR ((portal) NEAR/6 (flow* OR vein* OR system*)) OR bloodflow* OR blood-flow* OR circulation* OR ((hepat* OR liver*) NEAR/3 (arter*))):ab,ti,kw) AND ('surgical technique'/de OR 'anastomosis'/de OR 'artery anastomosis'/exp OR 'vein anastomosis'/exp OR 'revascularization'/exp OR 'vascularization'/exp OR (anastomo* OR revasculari* OR vasculari* OR ((surg* OR operati*) NEAR/3 (technique* OR procedure* OR method*)) OR ((compar* OR method*) NEAR/3 (reperfusion* OR perfusion*))):ab,ti,kw) NOT ([Conference Abstract]/lim OR [Letter]/lim OR [Note]/lim OR [Editorial]/lim) NOT ([animals]/lim NOT [humans]/lim) AND [English]/lim24672446Medline Ovid(exp Liver Transplantation/ OR (Liver/ AND (Transplantation/ OR Transplantation.fs. OR Tissue Donors/ OR Organ Transplantation/)) OR (((liver* OR hepatic*) ADJ6 (transplant* OR homotransplant* OR allotransplant* OR graft* OR homograft* OR allograft* OR donor* OR donation))).ab,ti,kw) AND (exp Reperfusion/ OR exp Perfusion/ OR Portal System/ OR exp Hepatic Artery/ OR Blood Circulation/ OR exp Liver Circulation/ OR (reperfusion* OR perfusion* OR ((portal) ADJ6 (flow* OR vein* OR system*)) OR bloodflow* OR blood-flow* OR circulation* OR ((hepat* OR liver*) ADJ3 (arter*))).ab,ti,kw) AND ("Surgical Procedures, Operative"/ OR exp "Anastomosis, Surgical"/ OR (anastomo* OR revasculari* OR vasculari* OR ((surg* OR operati*) ADJ3 (technique* OR procedure* OR method*)) OR ((compar* OR method*) ADJ3 (reperfusion* OR perfusion*))).ab,ti,kw) NOT (letter* OR news OR comment* OR editorial* OR congres* OR abstract* OR book* OR chapter* OR dissertation abstract*).pt. NOT (exp animals/ NOT humans/) AND english.la.1966538Cochrane CENTRAL((((liver* OR hepatic*) NEAR/6 (transplant* OR homotransplant* OR allotransplant* OR graft* OR homograft* OR allograft* OR donor* OR donation))):ab,ti,kw) AND ((reperfusion* OR perfusion* OR ((portal) NEAR/6 (flow* OR vein* OR system*)) OR bloodflow* OR blood-flow* OR circulation* OR ((hepat* OR liver*) NEAR/3 (arter*))):ab,ti,kw) AND ((anastomo* OR revasculari* OR vasculari* OR ((surg* OR operati*) NEAR/3 (technique* OR procedure* OR method*)) OR ((compar* OR method*) NEAR/3 (reperfusion* OR perfusion*))):ab,ti,kw)9547Web of scienceTS=(((((liver* OR hepatic*) NEAR/5 (transplant* OR homotransplant* OR allotransplant* OR graft* OR homograft* OR allograft* OR donor* OR donation)))) AND ((reperfusion* OR perfusion* OR ((portal) NEAR/5 (flow* OR vein* OR system*)) OR bloodflow* OR blood-flow* OR circulation* OR ((hepat* OR liver*) NEAR/2 (arter*)))) AND ((anastomo* OR revasculari* OR vasculari* OR ((surg* OR operati*) NEAR/2 (technique* OR procedure* OR method*)) OR ((compar* OR method*) NEAR/2 (reperfusion*OR perfusion*)))) NOT ((animal* OR rat OR rats OR mouse OR mice OR murine OR dog OR dogs OR canine OR cat OR cats OR feline OR rabbit OR cow OR cows OR bovine OR rodent* OR sheep OR ovine OR pig OR swine OR porcine OR veterinar* OR chick* OR zebrafish* OR baboon* OR nonhuman* OR primate* OR cattle* OR goose OR geese OR duck OR macaque* OR avian* OR bird* OR fish*) NOT (human* OR patient* OR women OR woman OR men OR man))) AND DT=(Article) AND LA=(English)1403277Google scholar (top 200 references)"liver|hepatic transplantation|graft|allograft|donation" reperfusion|perfusion|circulation|bloodflow|"portal|blood flow"|"portal vein"|"hepatic|liver artery" anastomosis|revascularization|"surgical|operative technique|procedure|method" 200114Total61313422Table S2. Hemodynamic and metabolic changesReferenceNumber of patientsHemodynamicsTissue oxygenation and metabolic changesSankary et al. PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5TYW5rYXJ5PC9BdXRob3I+PFllYXI+MTk5NTwvWWVhcj48

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ADDIN EN.CITE.DATA (26)31 SimR* vs. 71 IPR?N/A||N/A||Baccarani et al. PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5CYWNjYXJhbmk8L0F1dGhvcj48WWVhcj4yMDEyPC9ZZWFy

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ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5CYWNjYXJhbmk8L0F1dGhvcj48WWVhcj4yMDEyPC9ZZWFy

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ADDIN EN.CITE.DATA (31)42 SimR* vs. 38 IPR?PRS? 8 (19%) vs. 4 (11%)N/A||Lu et al. PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5MdTwvQXV0aG9yPjxZZWFyPjIwMTQ8L1llYXI+PFJlY051

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RW5kTm90ZT5=

ADDIN EN.CITE.DATA (22)15 IAR? vs. 14 IPR?PRS? 4 (26%) vs. 6 (42%)Uniform and diffuse reperfusion 15 (100%) vs. 10 (71%)∏Graft edema 2 (13%) vs. 8 (57%)∏N/A||Ducerf et al. PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5EdWNlcmY8L0F1dGhvcj48WWVhcj4yMDAwPC9ZZWFyPjxS

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ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5EdWNlcmY8L0F1dGhvcj48WWVhcj4yMDAwPC9ZZWFyPjxS

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PC9yZWNvcmQ+PC9DaXRlPjwvRW5kTm90ZT4A

ADDIN EN.CITE.DATA (24)29 IAR? vs. 30 IPR?More homogenous reperfusion in IAR?Signs of PRS? in IPR? group; significant decrease of MAP#, increase of CVP**, increase of CarI??, decrease of SVRa, increase of mean PCPb after reperfusion (15 minutes)N/A||Sadler et al. PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5TYWRsZXI8L0F1dGhvcj48WWVhcj4yMDAxPC9ZZWFyPjxS

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ADDIN EN.CITE.DATA (27)10 IAR? vs. 10 IPR?No significant differences between groups regards MAP#Median dose of epinephrine use (0 vs. 0.02 mg) ∏No differences between groups in lactate and bicarbonate concentrationHigher oxygen consumption in IPR? group; similar changes in carbon dioxide eliminationMoreno et al. PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5Nb3Jlbm88L0F1dGhvcj48WWVhcj4yMDA2PC9ZZWFyPjxS

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ADDIN EN.CITE.DATA (29)66 SimR* vs. 65 ICR§N/A||N/A||Cai et al. PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5DYWk8L0F1dGhvcj48WWVhcj4yMDE2PC9ZZWFyPjxSZWNO

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ADDIN EN.CITE.DATA (35)53 ICR§ vs. 21 IPR?N/A||N/A||SimR*, simultaneous re-vascularization; IPR?, initial portal reperfusion; IAR?, initial arterial reperfusion; ICR§, initial caval reperfusion; N/A||, non-available;PRS?, post-reperfusion syndrome; MAP#, mean arterial pressure; CVP**, central venous pressure; CarI??, cardiac index; SVRa, systemic vascular resistance; PCPb, pulmonary capillary pressure; MPPc, mean pulmonary pressure; COd, cardiac output;∏P < 0.05Figure S1. Comparison of primary non-function for liver grafts re-perfused with simultaneous revascularization (SimR) and initial portal revascularization (IPR)Figure S2. Comparison of primary non-function for liver grafts re-perfused with initial arterial revascularization (IAR) and initial portal revascularization (IPR)Figure S3. Comparison of primary non-function for liver grafts re-perfused with simultaneous revascularization (SimR) and initial caval re-vascularization (ICR) Figure S4. Comparison of vascular complications for liver grafts re-perfused with simultaneous revascularization (SimR) and initial portal revascularization (IPR)Figure S5. Comparison of vascular complications for liver grafts re-perfused with initial arterial revascularization (IAR) and initial portal revascularization (IPR)Figure S6. Comparison of liver re-transplantations for liver grafts re-perfused with simultaneous revascularization (SimR) and initial portal revascularization (IPR)Figure S7. Comparison of liver re-transplantations for liver grafts re-perfused with initial arterial revascularization (IAR) and initial portal revascularization (IPR)Figure S8. Comparison of and post-reperfusion syndrome for liver grafts re-perfused with initial arterial revascularization (IAR) and initial portal revascularization (IPR) ................
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