PDF Insulin Does Not Mediate Glucose Stimulation of Proinsulin ...

Insulin Does Not Mediate Glucose Stimulation of Proinsulin Biosynthesis Gil Leibowitz, Andrei I. Oprescu, Go¨khan U¨c¸kaya, David J. Gross, Erol Cerasi, and Nurit Kaiser It has recently been suggested that insulin augments its own production by a physiologically important feed-forward autocrine loop. We studied the kinetics of ................
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