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Chandra Srinivasan, MD, FHRS, CEPS, CCDSAssociate Professor of Pediatrics (Cardiology)Section of Pediatric & Adult Congenital Cardiac ElectrophysiologyDivision of Pediatric CardiologyDepartment of PediatricsMcGovern Medical SchoolThe University of Texas Health Science Center at HoustonChildren’s Memorial Hermann HospitalWORK ADDRESS: 6410 Fannin, Ste 425, Houston, Texas 77030EMAIL: Chandra.Srinivasan@uth.tmc.eduACADEMIC & ADMINISTRATIVE APPOINTMENTS:2019 - Associate Professor of PediatricsSection of Pediatric & Adult Congenital Cardiac ElectrophysiologyDivision of Pediatric CardiologyMcGovern Medical School at HoustonUniversity of Texas Health Science Center at HoustonChildren’s Memorial Hermann Hospital2013 - 2019Assistant Professor of PediatricsSection of Pediatric & Adult Congenital Cardiac ElectrophysiologyDivision of Pediatric CardiologyMcGovern Medical School at HoustonUniversity of Texas Health Science Center at HoustonChildren’s Memorial Hermann Hospital2014 - Director, Ambulatory Arrhythmia MonitoringDirector, Genetic Arrhythmia ClinicDivision of Pediatric CardiologyUniversity of Texas Health Science Center at Houston2010 – 2011Cardiology InstructorDivision of Pediatric CardiologyTexas Children’s HospitalBaylor College of MedicineHouston, TX, USA2003 – 2004Senior Registrar in PediatricsDepartment of Pediatrics, Advanced Pediatrics CenterPost Graduate Institute of Medical Education and Research (PGIMER),Chandigarh, IndiaPOSTGRADUATE TRAINING:2011 – 2012Advanced Fellowship in Pediatric Cardiac ElectrophysiologyDuke University Medical CenterDurham, North Carolina2007 – 2010Post-doctoral Fellowship – Pediatric CardiologyComer Children’s HospitalUniversity of Chicago HospitalsChicago, Illinois (July 2007 – August 2007)Arkansas Children’s HospitalUniversity of Arkansas for Medical SciencesLittle Rock, Arkansas (September 2007 – June 2010)2005 – 2007Residency – Pediatrics (US)Department of PediatricsNew York University School of MedicineNew York University Medical CenterNew York, New YorkInternship year (US) waived by American Board of Pediatrics as credit to training in Pediatrics from India2000 – 2003Residency – Pediatrics (India)Post Graduate Institute of Medical Education and Research (PGIMER)Chandigarh, India (MD)GRADUATE EDUCATION: 1993 – 1999University of Kerala, Medical College, Trivandrum, India (MBBS)OTHER TRAINING:2012 - 2013‘Data Analysis’ CourseCoursera course offered byDepartment of BiostatisticsJohns Hopkins University, Baltimore, MD2009 – 2010‘Statistical Methods in Clinical Trials’ CourseUniversity of Arkansas for Medical Sciences, Little Rock, AR.LICENSURE:Illinois:# 036118771, Inactive since July 2011North Carolina:# 2011-00858, Issuance date 6/2/2011 Expired 3/15/2013Texas:# N6678, Issuance date 06/04/2010 - PresentCERTIFICATION:Board certified in Adult Congenital Heart DiseaseAmerican Board of Internal MedicineNovember 2019Certification Examination for Competency in Cardiac Rhythm Device Therapy (CCDS) conducted byInternational Board of Heart Rhythm Examiners (IBHRE):October 2015Certification Examination for Competency in Cardiac Electrophysiology (CEPS) conducted by International Board of Heart Rhythm Examiners (IBHRE):February 2014Board certified in Pediatric CardiologyAmerican Board of Pediatrics:November 2010Diplomate, General PediatricsAmerican Board of Pediatrics:October 2007Educational Commission for Foreign Medical Graduates:January 2005(USMLE Step 1, Step 2, Step 3)Pediatric Advanced Life Support (PALS)Adult Cardiac Life Support (ACLS)PROFESSIONAL ORGANIZATIONS:2014 -Fellow of the Heart Rhythm Society (FHRS)2011 - Pediatric and Congenital Electrophysiology Society (Member)2015 - Pediatric and Congenital Electrophysiology Society (PACES) Task Force for the Prevention of Sudden Death in the Young2005 -American Academy of Pediatrics2007 – Present: AAP Section on Cardiology & Cardiac Surgery2008 – Fellow of the American Academy of Pediatrics (FAAP)2007 -American Heart Association (Member)Council on Cardiovascular Disease in the YoungHONORS AND AWARDS:2018 – 2019Dean’s Teaching Excellence Awardat McGovern Medical School at Houston2016 – 2017Dean’s Teaching Excellence Awardat McGovern Medical School at Houston2013 – 2014Dean’s Teaching Excellence Award at University of Texas Medical School at Houston2014 – 2019Houstonia Top Doctors – Top Houston PhysiciansHoustonia Magazine2006 – 2007Resident of the Year Awarded by the Division of Neonatal Perinatal MedicineNew York University School of Medicine EDITORIAL POSITIONS:World Journal for Pediatric and Congenital Heart SurgeryArchives of Diseases in ChildhoodAnnals of Pediatric CardiologyExpert Review of Cardiovascular TherapyUltrasound in Obstetrics & GynecologySERVICE ON NATIONAL COMMITTEES: 2015 - Pediatric and Congenital Electrophysiology Society (PACES) Task Force for the Prevention of Sudden Death in the YoungSERVICE ON THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON COMMITTEES:Adult Congenital Heart Disease Comprehensive Center Certification CommitteeSERVICE ON McGOVERN MEDICAL SCHOOL at UTHEALTH COMMITTEES:2015 –Pediatric Cardiology Fellowship Clinical Competency CommitteeUniversity of Texas Health Science Center at HoustonMcGovern Medical School, Houston, Texas2019 –Graduate Medical Education CommitteeMcGovern Medical School, Houston, TexasMENTORSHIP:Helene Weideman (2019 - Present) - Medical Student, McGovern Medical School, Clinical Research Mentor / AdvisorAna Vasquez Choy, MD (2018 – Present) – Pediatrics Resident, Research AdvisorLi Xiong, MD (2016 – 2019) – Pediatric Cardiology Fellow, Clinical Preceptor, Research Advisor, SOC committee memberDurga Naidu, MBBS (2013 – 2016) – Pediatric Cardiology Fellow, Clinical Preceptor, Research Advisor, SOC committee memberYulia Turiy, MD (2014 – 2015) – Pediatric Cardiology Fellow, Clinical Preceptor, Research Advisor, SOC committee memberArpan Doshi, MBBS (2013 – 2014) – Pediatric Cardiology Fellow, Clinical Preceptor, Research Advisor, SOC committee memberCURRENT TEACHING RESPONSIBILITIES:Medical Student clinical instruction – 3rd year core rotationclinical instruction – 4th year outpatient electiveDidactic Lecture for Medical Students (MSIII) in ‘Cyanotic Congenital Heart DiseasePediatric Resident education – inpatient and outpatient teachingFellow EducationDidactic Lecture Series on topics in Heart Rhythm Disorders“Mechanism of Arrhythmias” – Annual lecture to Pediatric Cardiology Fellows“Pacemakers - Basics” – Annual lecture to Pediatric Cardiology Fellows“Sudden Cardiac Death and Inherited Primary Arrhythmia Syndromes” – Annual lecture to Pediatric Cardiology Fellows“Approach to Tachyarrhythmias”, “Anti-Arrhythmic Drugs” – Annual lecture to Pediatric Critical Care Medicine Fellows“Neonatal Tachyarrhythmias”, “Fetal Arrhythmias”, Anti-arrhythmic Drugs” – Annual lecture to Neonatal-Perinatal Medicine FellowsNeonatal simulation lab on ‘Arrhythmias’ for Neonatal-Perinatal Medicine FellowsModerator – Pediatric Cardiac Electrophysiology Conference (weekly)Advisor – Pediatric Cardiology Fellowship Journal Club (monthly)Nursing & ancillary support staff“Heart2Heart” Lecture Series – Children’s Heart Center, Children’s Memorial Hermann Hospital. Education of nursing and support staff in pediatric intensive care unitEducation of nursing and ancillary support staff in Pediatric Cardiac Electrophysiology laboratoryMENTORING ACTIVITIES:Pediatric Resident Mentor – advising and research participation with pediatric residents planning on careers in pediatric cardiologyPediatric Cardiology Fellow Mentor – advising and research participation with pediatric cardiology fellowsCURRENT CLINICAL SERVICE RESPONSIBILITIES:Faculty in Pediatric & Adult Congenital Cardiac ElectrophysiologyChildren’s Memorial Hermann Hospital Heart Center inpatient service: the inpatient service responsibility includes active participation and co-management of patients post-operative to cardiac surgery in the PICU, co-management of patients with congenital heart disease in the NICU, management of patients in the IMU and other hospital services, and consultation in the ICUs, pediatric wards, and emergency center Catheter ablation & other electrophysiology interventions in Pediatric & Adult Congenital Heart Disease patientsPerform Cardiac Rhythm Device Implantation, Cardiac Resynchronization in Pediatric & Adult Congenital Heart Disease patients Director, Ambulatory Arrhythmia Monitoring: Covering pediatric cardiology outpatient clinic at Texas Medical Center and 6 other outreach UT pediatric cardiology clinics.Director, Genetic Arrhythmia Clinic: Genetic Arrhythmia Clinic for Primary Inherited Arrhythmia Syndromes offering evaluation and management including genetic testing and genetic counseling services (monthly)Electrophysiology faculty team member of the Adult Congenital Heart Disease Program, Memorial Hermann Hospital/University of Texas Health Science Center at Houston, Texas Medical CenterRemote monitoring program for cardiac rhythm devices (Pacemaker / ICD): Manage remote monitoring program to periodically evaluated patients with cardiac rhythm devices from homeManagement of pacemakers and ICD in patients with non-MR conditional systems particularly epicardial systems undergoing MRI studies - Developed institutional protocol for Children’s Memorial Hermann Hospital Heart CenterPediatric Cardiac Rhythm Management Clinics at Texas Medical Center and The WoodlandsCardiac Rhythm Device clinic at UT Health, Texas Medical CenterPediatric Cardiology outpatient clinic at UT Health, Texas Medical CenterRESEARCH & ACADEMIC PRESENTATIONS:REFEREED ORIGINAL ABSTRACTS & ARTICLESGautam N.K., Turiy, Y., Srinivasan, C.: Preincision Initiation of Dexmedetomidine Maximally Reduces the Risk of Junctional Ectopic Tachycardia in Children Undergoing Ventricular Septal Defect Repairs. J Cardiothorac Vasc Anesth. 2017 Apr 10.Lingappan, K., Kaiser, J.R., Srinivasan, C., Gunn, A.J.,: Relationship between PCO2 and Unfavorable Outcome in Infants with Moderate-to-Severe Hypoxic Ischemic Encephalopathy. Pediatric Res. 2016 Apr 6.Lingappan, K., Srinivasan, C., Jiang, W., Wang, L., Couroucli, X., and Moorthy, B.: Analysis of the Transcriptome in Hyperoxic Lung Injury and Sex-Specific Alterations in Gene Expression. PloS One, 9(7), e101581.Srinivasan, C., Sachdeva, R., Morrow, W.R., Greenberg, S.B, Vyas, H.V.: Limitations of Standard Echocardiographic Methods for Quantification of Right Ventricular Size and Function in Children and Young Adults. J Ultrasound Med. 2011 Apr;30(4):487-93.Srinivasan, C., Jaquiss, R.D.B., Morrow, W.R., Frazier, E.A., Martin, D., Imamura, M., and Sachdeva, R.: Impact of Staged Palliation on Somatic Growth in Patients with Hypoplastic Left Heart Syndrome. Congenit Heart Dis. 2010 Nov;5(6):546-51.Srinivasan, C., Sachdeva, R, Morrow, W.R, Gossett, J, Chipman, C.W., Imamura, M., and Jaquiss, R.D.B.: Standardized Management Improves Outcomes after Norwood Procedure. Congenit Heart Dis. 2009 Sep;4(5):329-37.INVITED REVIEW ARTICLESrinivasan C., Balaji S.: Neonatal Supraventricular Tachycardia. Indian Pacing Electrophysiol J 2019;33:678–83.Srinivasan, C.: Diagnosis and Acute Management of Tachyarrhythmias in Children. Indian J Pediatr. 2015 Sep 28:1–7.MANUSCRIPTS UNDER REVIEWMartinez-Moreno, R., Selga, E., Riuro?, H., Mered S Parnes, M.S., Srinivasan, C., Wangler, M.F., Guillermo J Pe?rez, G.J., Scornik, F.S., Brugada, R.: An SCN1B variant affects both cardiac-type (NaV1.5) and brain-type (NaV1.1) sodium currents and contributes to complex concomitant brain and cardiac disorders. Frontiers in Cell and Developmental Biology.PEER-REVIEWED ABSTRACT PRESENTATIONSNATIONAL3/2020: Vasquez-Choy, A.I., Srinivasan, C..: Mobile Cardiac Telemetry in Evaluation of Children Presenting with Paroxysmal Symptoms Suggestive of Tachyarrhythmia: Comparison to Conventional Methods of Ambulatory Electrocardiographic Monitoring. Virtual Poster Presentation at Annual Scientific Sessions, American College of Cardiology 2020, Chicago, Illinois (Held as virtual conference due to Covid-19 Pandemic).5/2018: Srinivasan, C., Lemons, J., Poon, N.: Inherited Atrial Standstill in Child Associated with a Variant In SCN1B Gene. Featured Poster Presentation at Annual Scientific Sessions, Heart Rhythm 2018, Boston, Massachusetts.5/2015: Srinivasan, C., Hines, M.H., Raymond, B., Numan, M.T.: Complete Failure of Internal Defibrillation with Epicardial-Transvenous Hybrid Implantable Defibrillator System in Danon Disease. Provocative Case Report: Poster Presentation at Annual Scientific Sessions, Heart Rhythm 2015, Boston, Massachusetts.11/2014: Doshi, A.R., Srinivasan, C., Desai, H.H., Moulik, M.: Impact of 2007 American Heart Association Infective Endocarditis Prevention Guidelines on Pediatric Hospital Admissions: A US Population-Based Study. Accepted for Oral Podium Presentation at American Heart Association, Annual Meeting, Chicago, Illinois.10/2014: Doshi, A.R., Srinivasan, C., Desai, H.H., Moulik, M.: Impact of 2007 American Heart Association Infective Endocarditis Prevention Guidelines on Pediatric Hospital Admissions: A US Population-Based Study. Accepted for Young Investigator Award Category Abstract Presentation at American Academy of Pediatrics, Annual Meeting, San Diego, California.5/2014: Srinivasan, C., Moulik, M., Numan, M.T.: Use of Implantable Cardioverter-Defibrillator and Sympathetic Denervation for Long QT Syndrome in Children and Adolescents: A Population-Based Study. Poster Presentation at Annual Scientific Sessions, Heart Rhythm 2014, San Francisco, California.11/2012: Srinivasan, C., Hornik, C.P., Lloyd, A., Meliones, C., Carboni, M.P., Darden, W., and Kanter, R.J.: Evaluation of Syncope and Its Electrophysiological Associations in Children and Adolescents: A Pediatric Referral Center Experience. Poster presentation at American Heart Association, Annual Meeting, Los Angeles, California.10/2012: Srinivasan, C., Hornik, C.P., Lloyd, A., Meliones, C., Carboni, M.P., Darden, W., and Kanter, R.J.: Evaluation of Syncope and Its Electrophysiological Associations in Children and Adolescents: A Pediatric Referral Center Experience. Accepted for poster presentation at American Academy of Pediatrics, Annual Meeting, New Orleans, Louisiana.6/2012: Pignatelli, R., Srinivasan, C., Xu, A., Cui, Q., Denfield, S., Jefferies, J., Ater, J.: Abnormal Myocardial Strain and Preserved Ejection Fraction in Children with Chemotherapy-related Cardiotoxicity. Oral podium presentation at the American Society of Echocardiography 23rd Annual Scientific Sessions, National Harbor, Maryland, USA.9/2011: Pignatelli, R., Srinivasan, C., Xu, A., Cui, Q., Denfield, S., Jefferies, J., Ater, J.: Abnormal Myocardial Strain and Preserved Ejection Fraction in Children with Chemotherapy-related Cardiotoxicity. Poster presentation at European Symposium on Late Complications after Childhood Cancer, Amsterdam, Netherlands.5/2011: Srinivasan, C., Rossano, J.W., Decker, J.A., Macicek, S.L., Kim, J.J.: Increased Mortality, Morbidity and Inpatient Care Costs Associated with Arrhythmias in Pediatric Cardiomyopathy: A Population-Based Study. Featured Poster Presentation at Annual Scientific Sessions, Heart Rhythm 2011, San Francisco, California.5/2011: Macicek, S.L., Shah, K., Moffett, B., Decker, J.A., Friedman, R.A., Srinivasan, C., Kim, J.J.: Drug Induced QT Prolongation and Associated Outcomes in Children Admitted to a Pediatric Tertiary Care Hospital. Podium presentation at Annual Scientific Sessions, Heart Rhythm 2011, San Francisco, California.4/2009: Srinivasan, C., Jaquiss, R.D.B.,, Morrow, W.R., Frazier, E.A., Martin, D., Imamura, M., Sachdeva, R.: Growth in Patients from Norwood to Fontan. Young Investigator Award Category Abstract Presentation at American Academy of Pediatrics, Annual Meeting, Washington DC 2009.11/2008: Srinivasan, C., Sachdeva, R, Morrow, W.R, Gossett, J, Chipman, C.W., Imamura, M., Jaquiss, R.D.B.: Standardized Management Improves Outcomes after Norwood Procedure. Abstract accepted for poster presentation at American Heart Association, Annual Conference, New Orleans 2008.10/2008: Srinivasan, C., Sachdeva, R, Morrow, W.R, Gossett, J, Chipman, C.W., Imamura, M., Jaquiss, R.D.B.: Standardized Management Improves Outcomes after Norwood Procedure. Young Investigator Award Category Abstract Presentation at American Academy of Pediatrics, Annual Meeting, Boston, Massachusetts. 10/2008: Srinivasan, C., Sachdeva, R., Morrow, W.R., Greenberg, S.B, Vyas, H.V.: Limitations of ASE recommended parameters of RV size and function by 2D echo: comparison with cardiac MRI. Oral podium presentation at American Academy of Pediatrics, Annual Meeting, Boston, Massachusetts.10/2008: Srinivasan, C., Sachdeva, R., Morrow, W.R., Greenberg, S.B, Vyas, H.V.: Limitations of ASE recommended parameters of RV size and function by 2D echo: comparison with cardiac MRI. Oral podium presentation at North American Society of Cardiovascular Imaging, Annual Meeting, Glendale, Arizona.INTERNATIONAL7/2017: Harris, A.D., Biliciler-Denktas, G., Moulik, M., Douglas, W.I., Srinivasan, C.: Permanent Pacemaker Implantation via Iliac Vein in Single Ventricle Patient after Bidirectional Glenn Procedure. Poster presentation at 7th World Congress of Pediatric Cardiology and Cardiac Surgery, Barcelona, Spain.7/2017: Harris, A.D., Biliciler-Denktas, G., Srinivasan, C.: Management of Acute Flecainide Toxicity in Infants with High Dose Intravenous Sodium Bicarbonate. Poster presentation at 7th World Congress of Pediatric Cardiology and Cardiac Surgery, Barcelona, Spain.7/2017: Bhatia-Barnes, J., Breinholt, J.P, Srinivasan, C.: Relapsed Acute Lymphocytic Leukemia (ALL) Presenting as Complete Atrioventricular Block. Poster presentation at 7th World Congress of Pediatric Cardiology and Cardiac Surgery, Barcelona, Spain. 5/2014: Lingappan, K., Srinivasan, C., Kaiser, J.R., and Gunn, J.A.: Relationship Between PCO2 and Neurological Outcome in Neonates with Hypoxic Ischemic Encephalopathy (HIE): Secondary Analysis of the CoolCap Study. Poster presentation at Pediatric Academic Societies, Annual Meeting, Vancouver, Canada.INVITED PRESENTATIONSLOCAL10/2017: “Approach to Tachyarrhythmias”, “Anti-Arrhythmic Drugs” – Pediatric Critical Care Medicine Fellows Lecture Series, University of Texas Health Science Center, Houston, TX, USA9/2017: “Neonatal Tachyarrhythmias”, “Fetal Arrhythmias”, Anti-arrhythmic Drugs” – Annual lecture to Neonatal-Perinatal Medicine Fellows Lecture Series, University of Texas Health Science Center, Houston, TX, USA9/2016: “Neonatal Tachyarrhythmias”, “Fetal Arrhythmias”, Anti-arrhythmic Drugs” – Annual lecture to Neonatal-Perinatal Medicine Fellows Lecture Series, University of Texas Health Science Center, Houston, TX, USA10/2015: “Tools for Arrhythmia Diagnosis: Past, Present and Future” - Grand Rounds – Pediatrics, At University of Texas Medical School at Houston, TX, USA9/2015: “Arrhythmias and Conduction Disease in Adult Congenital Heart Disease” - Grand Rounds – Cardiology Internal Medicine, At University of Texas Medical School at Houston, TX, USA7/2015: “Pediatric Tachyarrhythmias & Channelopathies” – Emergency Medicine Resident Lecture Series, at University of Texas Health Science Center, Houston, TX, USA6/2015: “Electrocardiogram Interpretation: For Neonatal ICU” – Neonatal ICU Cardiovascular Symposium, Children’s Memorial Hermann Hospital, Houston, TX, USA1/2011: “Channelopathies: Focus on Long QT Syndrome” – Pediatric Cardiology Fellow Lecture Series, Baylor College of Medicine/Texas Children’s Hospital, Houston, TX, USAREGIONAL6/2018: “Why is my child passing out?” – Invited talk at the 67th Annual Conference on Advances in Pediatrics, sponsored by UTMB Department of Pediatrics, Galveston, TX, USA2/2018: “Prevention of Sudden Death in the Young” – Preventive Cardiology Forum XXVIII, UT McGovern Medical School, Houston, TX, USA10/2015: “Tools for Diagnosis and Management of Pediatric and Congenital Heart Rhythm Disorders” – ED Collaborative, Memorial Hermann Hospitals, Houston, TX, USA10/2014: “Inherited Primary Arrhythmia Syndromes: Cardiac Channelopathies” – Tenth Annual Pediatric Cardiology Symposium, Houston, TX, USA11/2013: “Dealing with Symptomatic & Asymptomatic Woff-Parkinson-White Pattern’ – Ninth Annual Pediatric Cardiology Symposium, Houston, TX, USAONGOING PROJECTSMulti-center Study: Co-Principal Investigator with Svjetlana Tisma-Dupanovic and Seshadri Balaji: “Unexplained Ventricular Fibrillation in the Young”. Approved and endorsed by Pediatric and Congenital Electrophysiology Society (PACES).Helene Weideman and Chandra Srinivasan: Survey Project - Awareness of Strategies for Prevention of Sudden Cardiac Death in the Young. Administered to parents of middle and high school students and school administrators in Houston and suburbs. ................
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