VA/DoD Clinical Practice Guideline for the Management of ...
VA/DoD CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF
CHRONIC INSOMNIA DISORDER AND OBSTRUCTIVE SLEEP APNEA
Department of Veterans Affairs Department of Defense
QUALIFYING STATEMENTS
The Department of Veterans Affairs and the Department of Defense guidelines are based upon the best information available at the time of publication. They are designed to provide information and assist decision making. They are not intended to define a standard of care and should not be construed as one. Neither should they be interpreted as prescribing an exclusive course of management.
This Clinical Practice Guideline is based on a systematic review of both clinical and epidemiological evidence. Developed by a panel of multidisciplinary experts, it provides a clear explanation of the logical relationships between various care options and health outcomes while rating both the quality of the evidence and the strength of the recommendation.
Variations in practice will inevitably and appropriately occur when clinicians take into account the needs of individual patients, available resources, and limitations unique to an institution or type of practice. Every healthcare professional making use of these guidelines is responsible for evaluating the appropriateness of applying them in the setting of any particular clinical situation.
These guidelines are not intended to represent Department of Veterans Affairs or TRICARE policy. Further, inclusion of recommendations for specific testing and/or therapeutic interventions within these guidelines does not guarantee coverage of civilian sector care. Additional information on current TRICARE benefits may be found at tricare.mil or by contacting your regional TRICARE Managed Care Support Contractor.
Version 1.0 ? 2019
VA/DoD CPG for the Management of Chronic Insomnia Disorder and Obstructive Sleep Apnea
Prepared by:
The Management of Chronic Insomnia Disorder and Obstructive Sleep Apnea Work Group
With support from:
The Office of Quality, Safety and Value, VA, Washington, DC &
Office of Evidence Based Practice, U.S. Army Medical Command
Version 1.0 ? 2019 Based on evidence reviewed through May 2018
October 2019
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VA/DoD CPG for the Management of Chronic Insomnia Disorder and Obstructive Sleep Apnea
Table of Contents
I. Introduction..................................................................................................................................... 6
II. Background...................................................................................................................................... 6 A. Definitions and Scope .......................................................................................................................... 6 a. Chronic Insomnia Disorder .......................................................................................................... 6 b. Obstructive Sleep Apnea.............................................................................................................. 7 B. Epidemiology and Impact in the General Population ........................................................................ 7 C. Sleep Disorders in the Department of Defense and the Department of Veterans Affairs Populations .......................................................................................................................................... 8 a. Agenda for Increased Access to Behavioral Interventions for Insomnia Disorder.....................8 b. Agenda for Increased Access to Mandibular Advancement Device Therapy for Indicated Active Duty Service Members and Veterans ............................................................................... 9
III. About this Clinical Practice Guideline ............................................................................................. 10 A. Methods ............................................................................................................................................. 10 a. Grading Recommendations.......................................................................................................11 b. Peer Review Process .................................................................................................................. 12 B. Summary of Patient Focus Group Methods and Findings................................................................13 C. Conflicts of Interest ........................................................................................................................... 14 D. Scope of this Clinical Practice Guideline ........................................................................................... 14 E. Highlighted Features of this Clinical Practice Guideline ................................................................... 15 F. Patient-centered Care ....................................................................................................................... 15 G. Shared Decision Making .................................................................................................................... 16 H. Co-occurring Conditions .................................................................................................................... 16 I. Implementation ................................................................................................................................. 16
IV. Guideline Work Group ................................................................................................................... 18
V. Algorithm ...................................................................................................................................... 19 Module A: Screening for Sleep Disorders .......................................................................................... 20 Module B: Management of Chronic Insomnia Disorder ................................................................... 22 Module C: Management of Obstructive Sleep Apnea.......................................................................25
VI. Recommendations ......................................................................................................................... 27 A. Diagnosis and Assessment of Obstructive Sleep Apnea and Insomnia Disorder ............................ 30 B. Treatment and Management of Obstructive Sleep Apnea..............................................................36
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VA/DoD CPG for the Management of Chronic Insomnia Disorder and Obstructive Sleep Apnea
C. Treatment and Management of Chronic Insomnia Disorder...........................................................48 a. Behavioral and Psychological Treatments................................................................................48 b. Complementary and Integrative Health Treatments ............................................................... 55 c. Over-the-counter Treatments ................................................................................................... 59 d. Pharmacotherapy ...................................................................................................................... 64
D. Knowledge Gaps and Recommended Research...............................................................................72 a. Chronic Insomnia Disorder ........................................................................................................ 72 b. Obstructive Sleep Apnea............................................................................................................ 74
Appendix A: Evidence Review Methodology....................................................................................... 77 A. Developing the Key Questions .......................................................................................................... 77 a. Population(s).............................................................................................................................. 78 b. Interventions .............................................................................................................................. 78 c. Comparators .............................................................................................................................. 82 d. Outcomes ................................................................................................................................... 83 B. Conducting the Systematic Review...................................................................................................85 a. General Criteria for Inclusion in Systematic Review ................................................................. 89 b. Key Question Specific Criteria....................................................................................................89 C. Convening the Face-to-face Meeting................................................................................................90 D. Grading Recommendations...............................................................................................................90 E. Recommendation Categorization ..................................................................................................... 94 a. Recommendation Categories and Definitions .......................................................................... 94 b. Categorizing Recommendations ............................................................................................... 95 F. Drafting and Submitting the Final Clinical Practice Guideline.......................................................... 95
Appendix B: Provider Guide to Sleep Education for Insomnia Disorder ............................................... 97 A. General Information on Insomnia Disorder......................................................................................97 B. Goals of Insomnia Treatment............................................................................................................97 C. Describing CBT-I and BBT-I to Patients ............................................................................................. 98 D. Examples of Supporting Self-management Goals Related to the Stimulus Control and Sleep Restriction Components of CBT-I/BBT-I............................................................................................98
Appendix C: Provider Guide to Sleep Education for Obstructive Sleep Apnea ..................................... 99 A. General Information on Obstructive Sleep Apnea ........................................................................... 99 B. Diagnosing Sleep Apnea: Sleep Studies ............................................................................................ 99 C. Describing Sleep Apnea Treatment to Patients................................................................................99 D. Other Areas that Can Make Sleep Apnea Better or Worse............................................................100 E. Addressing Sleepiness ..................................................................................................................... 100 F. Addressing Adherence to Positive Airway Pressure.......................................................................100
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VA/DoD CPG for the Management of Chronic Insomnia Disorder and Obstructive Sleep Apnea
Appendix D: ICSD-3 Diagnostic Criteria ............................................................................................. 101 A. Chronic Insomnia Disorder .............................................................................................................. 101 a. Alternate Names......................................................................................................................101 b. Diagnostic Criteria ................................................................................................................... 101 B. Obstructive Sleep Apnea ................................................................................................................. 102 a. Alternate Names......................................................................................................................102 b. Diagnostic Criteria ................................................................................................................... 102
Appendix E: ISI and STOP Questionnaire Scoring Criteria .................................................................. 103 A. ISI ..................................................................................................................................................... 103 B. STOP Questionnaire........................................................................................................................104
Appendix F: DoD and VA Training in Behavioral Therapies for Insomnia Disorder ............................. 105
Appendix G: Patient Focus Group Methods and Findings .................................................................. 107 A. Methods ........................................................................................................................................... 107 B. Patient Focus Group Findings..........................................................................................................107
Appendix H: Evidence Table ............................................................................................................. 109
Appendix I: Participant List .............................................................................................................. 114
Appendix J: Literature Review Search Terms and Strategy ............................................................... 116 A. Syntax.........................................................................................................................116 a. Insomnia................................................................................................................................... 116 b. Obstructive Sleep Apnea.......................................................................................................... 120 B. MEDLINE Syntax...............................................................................................................................124 a. Insomnia................................................................................................................................... 124 b. Obstructive Sleep Apnea.......................................................................................................... 128 C. PsycINFO with Ovid Syntax..............................................................................................................132 a. Insomnia................................................................................................................................... 132 b. Obstructive Sleep Apnea.......................................................................................................... 136
Appendix K: Alternative Text Descriptions of Algorithms .................................................................. 137 Module A: Screening for Sleep Disorders ............................................................................................... 137 Module B: Management of Chronic Insomnia Disorder ........................................................................ 137 Module C: Management of Obstructive Sleep Apnea............................................................................138
Appendix L: Abbreviation List........................................................................................................... 140
References .......................................................................................................................................... 143
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