EMERGENCY MEDICINE Liverpool Hospital

Fentanyl . Metabolised in liver . Excreted inactive in liver so OK with renal failure . Patches come in 12mcg/24 hr, 25mcg or 50mcg . Wide difference in morphine equivalence eh 25mcg =30-100mg morphine/day. Takes 12-24 hrs to reach peak levels – activity 12-24 hrs after removal of patch . Difficult to titrate . Less constipating . Tramadol ................
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