In the second lab you will learn the basics of antibodies ...



Week 1 Blood Learning Objectives:Identify the cellular components of blood and state their functions.Explain the role of the white blood cells in protecting the body from disease.Analyze complete blood counts.Learn how to use an automatic hematology analyzer and how to prepare a peripheral smear.Name the 4 major blood types in the ABO system.Explain the principles of blood typing using Eldon cards.Describe Rh incompatibility and hemolytic disease of the newborn.Introduction: The body is a complex multicellular organism that comprises trillions of cells working together as tissues, organs, and systems. These cells require a continuous supply of oxygen and nutrients in order to function. They also need an efficient and fast means of delivery of these substances as well as a means of removing waste byproducts.Blood is composed of 2 components: blood plasma and the formed elements. In the first lab simulation, you will generate complete blood counts and prepare blood smears of control and patient samples to diagnose various blood disorders in three patients. Dive into the inner workings of the different blood components with immersive 3D animations, where you will get acquainted with the morphology and function of red blood cells, white blood cells, and platelets.In the second lab you will learn the basics of antibodies. Even though antibodies are proteins that protect us from harmful intruders, they can sometimes cause problems. You will learn about antibody-antigen interaction and the mechanism that lies behind Rh incompatibility. You will discover what antigens and antibodies have to do with blood type, and why mixing certain different blood types together can cause problems. In this simulation, you will examine blood samples from a mother and her unborn child, to determine whether or not they are compatible. Assignment:Part 1: Complete Labster “Hematology: Introduction to Blood”As you complete the lab, have the lab report ready to record data. The theory section of the lab is a useful resource.Part 2: Complete Labster “Antibodies: Why are some blood types incompatible?”As you complete the lab, have the lab report ready to record data. The theory section of the lab is a useful resource.Part 3: Complete the Lab report.Blood Lab ReportAnswer the following questions:Part 1 Lab questions:Identify the WBCs: (1 point each)Record the Data: (3 points)PatientCBC abnormalityPeripheral smear resultPatient 1Patient 2Patient 3 3. What is the importance of a complete blood count? (1 point)4. What information does a peripheral smear add to the results of a complete blood count? (1 point)5. Identify the diagnosis of the 3 patients in the Part 1 Labster lab as determined by their CBC and Peripheral Smear results. (3 points)Patient 1: Patient 2: Patient 3: Part 2 Lab questions:6. When is Rh incompatibility an issue for a pregnant woman and her baby? (1 point)7. What do the antibodies in the “Anti-D” test circle detect? (1 point)8. What is the cause of blood agglutination on the Eldon test cards? (1 point)9. Why can agglutination be lethal for a patient when it occurs during a blood transfusion? (1 point)10. Why is blood type O neg called the “universal donor”? (1 point)Grading Rubric for Lab ReportActivity?Deliverable?Points?Part 1Complete Labster “Hematology: Introduction to Blood”10Part 2Complete Labster “Antibodies: Why are some blood types incompatible?”10Part 3Complete lab report 10Total??Complete all lab activities??30 AbbreviationsCBC: complete blood count WBC: white blood cell ................
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