Power and Sample Size - University of Bristol
5% 0.9998 10% 1.0000 SD of methylation = 10% 4% 0.5710 5% 0.9512 10% 1.0000 SD of methylation = 12% 5% 0.6646 10% 1.0000 Blurb: There is more than 66% power to detect an absolute change in methylation of 5% between the two groups (n=280 vs990), assuming the variance in methylation is 12% or less, at the p x10-8 significance level. ................
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