DNA Structure & Replication



Name: __________________________________________________________ Date: ________ Period: ___

Guided Notes: DNA Structure & Replication

“A Winding Staircase”

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• DNA is a long molecule that is ________ _________________________________

• It is composed of ___________________ _________________________________

• Known as a _______________________

Nucleotides

• Nucleotides are ____________________ _________________________________

• Each nucleotide is made up of 3 parts:

1. ___________________________

2. ___________________________

3. ___________________________

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Label the above diagram like the power point

• Sugar and phosphate __________________ ________________________________________________________________________

• The nitrogen bases ____________________ ________________________________________________________________________

Nitrogen Bases

• In DNA, each nucleotide has the SAME ____________________________________, but it can have one of 4 bases:

o ______________________________

o ______________________________

o ______________________________

o ______________________________

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• The base pairing rule states that:

o ____________________________________________________________

o ____________________________________________________________

• Base pairs are held together by ____________________________________

How do cells make more DNA?

• Remember that BEFORE mitosis or meiosis can occur, __________________ _________________________________

• This process is called _______________

• Steps of DNA replication:

1. An enzyme (helicase) _________ ______________________________________________________

2. New _______________________ are added to each side

3. Another enzyme (DNA polymerase) _________________ _________________________________________________________________________________

• For the below DNA strand, build the complementary strand

A =

T =

T =

C =

G =

T =

A =

G =

C =

C =

A =

G =

[pic]

Show the complimentary base pairing that would occur in the replication of the short DNA molecule below. Use two different colored pencils (or different pens, markers, etc.) to show which strands are the original and which are newly synthesized.

[pic]

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