The Regulation of Fatty Acid Biosynthesis in Rat Hepatomas*

The fatty acid synthetic cycle begins with the acetyl-CoA carboxylase reaction. This is known to be the first committed step as well as rate limiting to overall fatty acid synthesis [22]. Aspects of this reaction will be the main focus of this thesis. In general the reaction takes acetyl-CoA along with free bicarbonate in order to generate ... ................
................