PDF Reperfusion Therapy for Acute Myocardial Infarction

REPERFUSION THERAPY FOR ACUTE MYOCARDIAL INFARCTION

Jason S. Go, MD, FACC Interventional Cardiology and Peripheral Vascular Intervention Altru Health System

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DISCLOSURES

CORONARY ARTERY DISEASE

? Major cause of morbidity and mortality in developed countries ? 2010 Heart disease and Stroke statistics

? 17.6 mil with CHD ? 8.5 mil with hx of MI ? 10.2 mil with angina

? 1/2 of all middle-age men and 1/3 of middle-age women will develop CHD ? Responsible for 1/3 of all deaths among individuals > 35 years old

CORONARY SYNDROMES

? CAD with Stable angina ? Unstable angina ? Non-ST elevation MI (NSTEMI) ? ST-elevation MI (STEMI)

ST SEGMENT ELEVATION MYOCARDIAL INFARCTION

? Presentation in up to 33% of ACS cases ? Diagnosis based on typical ST changes ? Usually represent an acute thrombotic occlusion of an epicardial coronary

artery ? Requires prompt recognition, triage, and reperfusion

WHY REPERFUSION?

? Addresses primary problem of acute STEMI ? Improves outcomes

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