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A safety signal of increased intracranial bleeding with ticagrelor vs. clopidogrel in patients with stroke/TIA history was not identified (0.9% vs. 0.7%; p >0.05), though the number of events was small.13 In the pivotal study evaluating prasugrel with clopidogrel, prasugrel was associated with a significant excess of intracranial bleeding ... ................
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