Australian public assessment report for taliglucerase alfa rpc
Of the 28 ERT experienced patients, 5 (17.9%) were found to have IgG ADA (3 adults, 2 children). Based on these figures, 24/71 (33.8%) patients were positive for treatment-induced IgG ADA, and the incidence of treatment-induced IgG ADA was notably higher in ERT naïve patients (44.2%) than in ERT experienced patients (17.9%). ................
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