STEROIDOGENESIS: An Overview
In the adrenal cortex (cortisol, aldosterone) ... All steroid hormones are synthesized from pregnenolone, a C 21 compound This substance results from the action of the side-chain cleavage enzyme complex (desmolase complex) on 20, 22-dihydroxycholesterol The process requires NADPH, oxygen, mitochondrial cytochrome P-450, adrenodoxin Side chain requires multiple hydroxylation reactions … ................
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