Curriculum vitae updated may, 1996



Curriculum Vitae

Paul S Phillips, MD

Office: San Diego Heart & Vascular

501 Washington Street, Ste 512

San Diego, CA 92103

Last Updated 2-14-11

PRESENT ACADEMIC RANK AND POSITION

Clinical Professor of Medicine (Non-salaried), UCSD Medical Center

200 West Arbor Street

San Diego, CA 92103 1987- .

Director Interventional Cardiology, Scripps-Mercy Medical Center

4077 Fifth Avenue

San Diego, CA 92103 1996- .

EDUCATION

BA Biochemistry

Magna Cum Laude, Phi Beta Kappa

University of Rochester; Rochester, NY 1976

Medical Degree

Alumnae Scholar, AOA

University of Rochester; Rochester, NY 1980

Internship and Residency

Kaiser Award for Excellence in Teaching (1983)

University of California; San Diego, CA 1980-1983

Chief Medical Resident

University of California; San Diego, CA 1983-1984

Cardiology Fellow

University of California; San Diego, CA 1984-1985

Cardiology Fellow

Mercy Hospital and Medical Center

RJ Prentiss Research Award (1985) 1985-1986

Additional Interventional Fellowship

Maurice Buchbinder; University of California; San Diego, CA 1986

Inteventional Sabbatical in Coronary Stenting

Carlos Macaya;Universitario San Carlos, Madrid Spain 1995-1996

BOARD CERTIFICATION& PROFESSIONAL CERTIFICATIONS

American Board of Internal Medicine 1983- .

American Board of Internal Medicine: Cardiology 1988- .

American Board of Internal Medicine: Critical Care Medicine 1990-1999

American Board of Internal Medicine: Interventional Cardiology 1999 - .

Recertified in 2007

Advanced Cardiac Life Support 1983- .

Advanced Cardiac Life Support Instructor 1985,1996

Advanced Trauma Life Support 1983-1990

Stent Implantation Certifications 1994,1995,2001,2003

Fellow, American College of Cardiology 1988-.

Fellow, American College of Physicians 1998-.

Society Cardiovascular Angiography and Interventions 2004-.

MEDICAL LICENSURE

State of California G 45869 1981- .

HONORS AND AWARDS

National Merit Scholar, Wilson Scholar 1972

Magna Cum Laude, Phi Beta Kappa

University of Rochester; Rochester, NY 1976

Alumnae Scholar, AOA

University of Rochester; Rochester, NY 1980

Kaiser Award for Excellence in Teaching

University of California; San Diego, CA 1983

RJ Prentiss Research Award 1985

Scripps Mercy Hospital

Medical Resident's Teacher of the Year

Mercy Medical Center 1991-1992

Cardiology Fellow's Teacher of the Year

Mercy Medical Center 1993-1994

Skaggs Clinical Scholar,

The Scripps Research Institute 2002- .

San Diego’s Top Doctor’s Distinction 2005, 2006, 2007

TEACHING AND FORMAL PRESENTATIONS

Director, Cardiology Fellows Clinic, Mercy Medical Center 1987-1995

Cardiology Consult Attending, UCSD Medical Center 1987-1989

Cardiology Consult Attending, Mercy Medical Center 1987- .

Cardiology ICU Rounds Attending, Mercy Medical Center 1987- .

PhD Thesis examiner, T. H. Eastwood, University of Melbourne 2010

Invited Lectures:

5-83 UCSD Medical Center Grand Rounds: High Output Congestive Heart Failure.

4-85 Mercy Medical Center Grand Rounds: Pericardial Diseases

3-85 St Joseph's Hospital Medical Grand Rounds: Modification of Cardiac Risk

2-86 Humboldt Regional Medical Meeting: The Advantages and Disadvantages of Calcium Channel Blockers.

8-87 Coronado Hospital Grand Rounds: The Use and Misuse of Cardiac Pacemakers.

10-20-87 Coronado Hospital Grand Rounds: PTCA 1987.

3-88 Coronado Hospital Grand Rounds: Management of Hypercholesterolemia.

5-7-92 Medical Housestaff Conference: Contemporary Management of Acute Myocardial Infarction.

6-9-92 Mercy Medical Center Grand Rounds: Diastolic Dysfunction: Is the Inability to Relax just a Problem for the Cardiologist?

3-94 Coronado Hospital Grand Rounds: The Regression of Coronary Atherosclerosis

5-31-94 Medical Housestaff Conference: Congestive Heart Failure and the Cardiomyopathies.

6-2-94 San Diego Critical Care Nursing Symposium: Management of Patients after Complex PTCA, Stents and Atherectomy.

2-7-95 Mercy Medical Center Grand Rounds: The Clinical Importance of Regression of Coronary Atherosclerosis

5-22-95 Medical Housestaff Conference: Congestive Heart Failure and the Cardiomyopathies.

2-15-96 Collaborative preparation of Talk: Different Stents for Different Indications presented at University Michigan Cath Conference by Dr. C. Macaya

5-13-96 Collaborative preparation of Talk: GP IIb/IIIa inhibitor therapy: Results of the CAPTURE Trial presented at Nice, France by Dr. C. Macaya

8-20-96 Mercy Medical Center Grand Rounds: Different Stents for Different Indications-- the future is happening now in Europe.

8-30-96 Sharp Memorial Hospital Cardiology Grand Rounds: Different Stents for Different Indications.

3-15-97 Mercy Medical Noon Conference: Anticoagulation Recommendations for Cardiac Disease/ Thrombolytic Choices and Primary Angioplasty.

8-14-97 South Bay Cardiology Dinner Speaker: Calcium Antagonist Therapy: What's New, What's Not.

10-8-97 UCSD Cardiology Grand Rounds Invited Speaker: Eclectic Stenting.

11-6-97 Cardiovascular Clinical Symposium: Stenting 1998: What does a Nurse need to know?

1-20-98 Mercy Medical Center Grand Rounds: Interventional Cardiology at Mercy Medical Center, 1997-- A database derived review of our interventional experience.

2-26-98 Mercy Nursing and Cardiovascular Technician Rounds: The Contemporary Management of Coronary Artery Disease.

4-06-98 Mercy Surgical Grand Rounds: Interventional Cardiology at Mercy Medical Center, 1997-- A database derived review of our interventional experience.

5-29-98 Mercy Health Clinics Staff Review: Office Management of CHF- What's new?

12/98 Scripps Mercy Medical Housestaff Conference: Management of Cardiac Catheterization Patients

1/99 Scripps Mercy Medical Grand Rounds: Interventional Cardiology at Mercy Medical Center

7-1-99 Scripps Mercy Medical Housestaff Conference: Housestaff Opportunities in the Management of Acute Myocardial Infarction.

9-28-99 Scripps Mercy Intermediate Unit Nursing Orientation: Management of Cardiac Catheterization Patients

3-99 Scripps Mercy Medical Housestaff Conference: Management of Acute Myocardial Infarction In the Cath Lab

5-99 Scripps Mercy Chest Pain Symposium: Management of Acute Myocardial Infarction Evidence Based Analysis of Therapies

3-15-99 Scripps Mercy Medical Housestaff Conference: M & M Review of Complications in Management of Acute Ischemic Syndrome

10-2-99 Scripps Mercy Chest Pain Symposium: Interventional Management of Myocardial Infarction

4-00 Guidant-Mammoth Cardiology Conference: The Importance of Hinge Point Morphology to Stent Restenosis

4-00 Guidant-Mammoth Cardiology Conference: Presentation of the Duet Stent Registry Data

6-2-00 San Diego Critical Care Nursing Symposium. What’s New in Cardiology for Critical Care Nurses.

9-27-00 Scripps Mercy Medical Housestaff Conference: Management of Acute Myocardial Infarction In the Cath Lab

9-28-01 Scripps Mercy Medical Housestaff Conference: Management of Acute Myocardial Infarction

2-3-01 Guidant Mammoth Cardiology Conference: Stenting in the New Millenium

2-26-01 San Diego Critical Care Nursing Symposium. What’s New in Cardiology for Critical Care Nurses.

3-9-01 Scripps Mercy Chest Pain Center Symposium. The Interventional Side of Acute Myocardial Infarction.

5-7-01 Scripps Chula Vista Grand Rounds: Contemporary Management of Coronary Artery Disease—Focus on 2b3a inhibitors.

7-8-01 Guidant Aviara Cardiology Conference: LIPID MANAGEMENT: New ATP III Guidelines and THE OTHER SIDE OF THE STATIN STORY

7-26-01 Scripps Mercy Medical Housestaff Conference: Hemodynamic Monitoring—It’s not a Swan Song.

8-30-01 Scripps Mercy Medical Housestaff Conference: Management of Acute Myocardial Infarction.

8-21-01 Scripps Mercy Medical Grand Rounds: CONTEMPORARY MANAGEMENT OF ACUTE CORONARY SYNDROMES

8-30-01 Scripps Mercy Housestaff Conference: The Interventional Approach to Acute Myocardial Infarction.

10-5-01 Scripps Mercy Maui Cardiology Symposium: The Preeminance of abciximab for Acute Coronary Syndromes.

1-15-02 Scripps Mercy Medical Grand Rounds: LIPID MANAGEMENT: New ATP III Guidelines and THE OTHER SIDE OF THE STATIN STORY

1-19-02 Grand Rounds—Hospital CIMA de Hermosillo, Mexico: Jornada de Cardioloia Invasiva: GP2b3a’s (en espanol).

2-08-02 Grand Rounds –Cardiology Sharp Memorial Hospital: Statin Associated Myopathy

2-9-02 Surgical Nursing CME Conference: LIPID MANAGEMENT: New ATP III Guidelines and THE OTHER SIDE OF THE STATIN STORY

6-12-02 Honolulu Cardiovascular Symposium: Use of 2b3a’s in ACS

02. Stein Eriksen Technology Conference 2002: Statin Therapy, Statin Associated Myopathy and Reason for Caution.

10-19-02 2nd Annual Maui Cardiovascular Symposium: Statins—the dark side.

12-10-02 UCSD Medical Grand Rounds: Statin-Associated Myopathy—New Insights.

1-22-03 Kaiser Permanente at Zion Grand Rounds: Statin-Associated Myopathy—New Insights.

4-14-03 Sharp Chula Vista Grand Rounds: Statin-Associated Myopathy—New Insights.

4-17-03 San Diego Neurology Society: Statin-Associated Myopathy—New Insights.

8-1-03 UCSD Graduate Physiology Research Meeting: Cardiopulmonary Exercise Testing Suggests Statin Myotoxicity is Related to Defective Mitochondrial Beta Oxidation.

2-25-04 UCSD Endocrinology and Metabolism Grand Rounds: Statin-Associated Myopathy from a Metabolic Perspective.

3-25-04 Expert Panelist at California State Heart Disease and Stroke Prevention Forum.

4-15-04 Cardiology Research Conference University California at Irvine.

5-19-04 Statin Myotoxicity—New Insights. Medical Grand Rounds, St. Francis Hospital, Roslyn, NY.

6-29-04 Statin Myotoxicity—Clinical Approach. Lipid Club, Purdue University, Indianapolis, IN

6-30-04 Statin Myotoxicity—Metabolic Perspectives. Endocrinology Grand Rounds, Purdue University, Indianapolis, IN.

8-5-04 Housestaff Opportunities in Acute MI (Resident’s Teaching Conference)

10-5-04 Statin Myopathy—Evidence suggests a metabolic disorder. Scripps Mercy Medical Grand Rounds.

11-30-04 Clinical, Physiological and Biochemical insights into statin myopathy. Beutler Lab Meeting, The Scripps Research Institute.

12-1-04, 12-4-04, 12-11-04 Intolerance of systemic Lipid-lowering therapies. Dana Point, CA; Santa Monica, CA; Coronado, CA.

3-8-05 Featured Session, American College of Cardiology Annual Sessions. Myotoxic Reactions to Lipid Lowering Therapies Are Mediated by Impaired Oxidation of Fats.

3-17-05 Intolerance to Systemic Lipid Lowering Therapy. Presenter for a national webcast.

5-12-05 Myotoxic Reactions to Lipid Lowering Therapies Are Mediated by Impaired Oxidation of Fats . Skaggs Clinical Scholar Presentation. La Jolla, CA.

8-2-05 Medical Grand Rounds, University of Connecticut, Hartford CT. Statin Myopathy: Evidence Suggests a Metabolic Disorder.

8-2-05 Clinical Cardiology Teaching Conference, University of Connecticut, Hartford CT. New Insights into Statin-induced Rhabdomyolysis.

8-5-05 Acute Coronary Syndromes: 2005. Clinical Cardiology Teaching conference, Scripps Mercy

11-30-05 New Insights Into Statin Muscle Toxicity. UCSD Cardiology Grand Rounds.

3-9-06 Clinical Evaluation of Statin Intolerance. Alvarado Hospital Grand Rounds.

3-10-06 Intolerance of Lipid-lowering Therapy. Pfizer National Web-conference.

3-21-06 Statin Muscle Toxicity--Diverse disorders with a common metabolic thread? UCSD Endocrinology Grand Rounds.

5-25-06 Contemporary management of ACS. Scripps Mercy Nursing Symposium

7-6-06 Statin-myotoxicity: A clinical case approach. Scripps Encinitas Neurology Grand Rounds.

12-11-7, 4-30-7, 5-1-7, 5-14-7, 5-15-7 Bare Metal Balance in Stenting. Dinner lectures on DES vs. Bare Metal Stenting in Kansas City, Tulsa, Oklahoma City, Columbia and St. Louis.

6-15-7 Cardiovascular Affects of Mitochondrial Diseases. United Mitochondrial disease Foundation, San Diego.

6-22-7 Statin Myopathy-2007 Update. Sharp Memorial Cardiology Grand Rounds, San Diego.

9-6-7 Management of Acute Coronary Syndromes. Medical Housestaff Noon Conference.

9-11-7 Bare metal vs. DES stenting. Sharp Memorial Chula Vista Cardiology Grand Rounds, San Diego.

9-14-7 Insights into statin-associated muscle disorders. UCLA Division of Rheumatology Grand Rounds.

10-13-7 Statin Myopathy Update, 2007. Sharp Memorial Cardiovascular Conference.

11-5-7 Meet the Experts/How to session, American Heart Association annual meeting: Statin myopathy as a metabolic disorder of fat metabolism.

12-3-7 Bare Metal Balance in Stenting. Dinner presentation, Wichita, KA

12-5-8 Measuring Muscle Toxicity: an exercise in scientific method. Pt. Loma Nazarene University AVID program.

1-3-8 Bare Metal Balance in Stenting. Scripps Mercy Medical Houstaff Lecture

1-28-8 Bare Metal Balance in Stenting. For Abbott Vascular, Temecula, CA

2-26-8 The Statin risk/benefit analysis in 2008. Cardiology Grand Rounds, Sharp Chula Vista Hospital.

3-6-8 Interesting Exercise. Scripps Mercy Medical Houstaff Lecture

4-22-8 The Statin risk/benefit analysis in 2008. Medical Grand Rounds, Scripps Memorial Hospital.

4-24-8 Quantitative approach to clinical research. Nursing Research Symposium, Scripps Mercy Hospital.

7-3-8 Management of ACS and STEMI. Scripps Mercy Medical Houstaff Lecture

10-10-8 Bivalirudin vs. Heparin & 2b3a’s for ACS/AMI. 10th Annual Sharp Cardiovascular Conference, Maui.

10-11-8 DES Platforms 2008: Can the stents speak for themselves? 10th Annual Sharp Cardiovascular Conference, Maui.

12-3-8 Measuring Muscle Toxicity: an exercise in scientific method. Pt. Loma Nazarene University AVID program.

4-9-9 DES, clopidogrel and other cardiac foibles for the internist. Scripps Mercy Medical Houstaff Lecture

7-2-9 Management of ACS and STEMI. Scripps Mercy Medical Houstaff Lecture

9-19-9 La Miopatia por Estatinas: Es possible tener demasiado de algo bueno? CICIG-2009. Guadalajara, Mexico.

9-22-9 Toward appropriate statin use-2009. Sharp Chula Vista Cardiology Grand Rounds.

10-27-9 A new advance in antiplatelet therapy for ACS. Sharp Chula Vista Cardiology Grand Rounds.

11-2-9 Prasugrel, a new antiplatelet therapy for ACS. XXVI Congress of Mexican Cardiology Society, Pueble, Mexico.

2-8-10 Hemodynamic Monitoring for Housestaff, 2010. Scripps Mercy Noontime teaching conference.

7-9-10 Housestaff Opportunities in Acute Coronary Syndromes, 2010. Scripps Mercy Resident Teaching Conference.

10-4-10 Statin Myopathy-what do we know after 25 years. UCSD Cardiology Grand Rounds.

INSTITUTIONAL, DIVISIONAL & DEPARTMENTAL ACTIVITIES

Internal Medicine Committee, Coronado Hospital 1987-1989

Critical Care Committee, Coronado Hospital 1987-1989

Quality Improvement, Coronado Hospital 1989-1993

Cardiology Supervisory Committee, Mercy Medical Center 1987- .

Cardiology Morbidity and Mortality Committee Director 1987- .

Cardiology Catheterization Conference Coordinator 1996- .

Ethics Committee, Chairman; Coronado Hospital 1998-1999

Ethics Committee, Scripps Mercy 1998- .

New Technologies Committee, Scripps Mercy 2000- 2004

Institutional Review Board, Scripps Mercy (Chair 2005-2007) 1999- 2008

PROFESSIONAL MEMBERSHIPS

San Diego County STEMI Advisory Committee 2006- .

Chairman 2006- 2008

American College of Physicians, Fellow 1980-2008

American College of Cardiology, Fellow 1987- .

American Heart Association 1987- .

Society of Cardiac Angiography and Interventions 2004- .

REVIEWER FOR

Annals of Family Medicine 2004- .

Cleveland Clinic Journal of Medicine 2004- .

Journal of the American College of Cardiology 2004- .

Nature Medicine Clinical Practice, Cardiovscular Medicine 2004- .

Drug Safety 2005- .

Neuromuscular Diseases 2006- .

Future Lipidology 2006- .

British Journal of Clinical Pharmacology 2006- .

American Journal of Medicine 2008- .

Current Drug Safety 2008- .

Muscle and Nerve 2009- .

Nature Reviews, Endocrinology 2009- .

The Journal of Rheumatology 2009- .

Circulation Research 2009- .

Cleveland Clinic Journal of Medicine 2009- .

CLINICAL INVESTIGATOR FOR FUNDED PROJECTS

GUSTO Genentech

GUSTO II b (Global Use of Strategies to Open Occluded Coronary Arteries) CIBA-Geigy, Boehringer-Mannheim, Advanced Cardiovascular Systems, Inc.

Benestent II Cordis 1995

CAPTURE 1995-1996

WEST Guidant 1996

SYMPHONY I and II (Sibrafiban versus aspirin to Yield Maximum Protection from ischemic Heart events post-acute corONary sYndromes); Hoffman-La Roche Ltd. 1998, 1999

GUSTO IV (Global Use of Strategies to Open Occluded Ckoronary Arteries); Randomized assessment of platelet glycoprotein Iib/IIIa inhibition and low dose fibrinolytic in acute myocardial infarction. Abciximab vs. placebo for acute coronary syndromes. Eli Lilly, Centocor, Inc.

POSTIT (Principal Investigator) A post marketing IVUS and angiographic evaluation of NIR vs. other stents. Boston Scientific

CACT (Principal Investigator) A prospective evaluation of how do physicians utilize their own coronary artery CT findings?

IMPOSTER (Principal Investigator) Is myopathy part of “statin” therapy? A prospective randomized double blind evaluation of muscle complaints in patients on “statin” therapy.

A to Z (Principal Investigator) A multicenter evaluation of low molecular weight heparin vs. unfractionated heparin in patients with acute ischemic syndromes.

OAT (Principal Investigator) The occluded artery trial is a multicenter evaluation of opening vs. leaving closed an occluded infarct artery (2000-2001).

FASTER (Principal Investigator) A multicenter evaluation of TNK-tPA and tirofiban to open arterys during acute myocardial infarction.

REPLACE 2 (Prinicipal Investigator) A multicenter evaluation of Bivalirudin vs. Heparin in PCI (2001-2002).

ACUITY 2004

TRACER 2009

BIBLIOGRAPHY

Books:

Phillips PS, Kern M, Serruys P: The Stenter's Notebook 211 pp. Published by Physician's Press, Birmingham, MI; 1998.

Scientific Articles:

Phillips PS, Verity MA, Schick BA, Vladutiu GD, Laaksonen R, Oresic M, Hohl RJ, Ciaraldi TP, Sukhatme VP, Lecker SH, Cote HCF, Powell H, Davidson W, Wolfson T. A Survey of Muscle Characteristics after Statin-Induced Rhabdomyolysis. Clinical Lipidology 2010; 5:17-27.

Phillips PS. Balancing Randomized Trials with Anecdote. Ann Intern Med. 2009;150:885-6.

Linares LA, Golomb B, Jaojoco J, Sikand H, Phillips PS. The Contemporary Spectrum of Rhabdomyolysis suggests its utility in assessing drug toxicity. Curr Drug Saf. 2009 Sep;4:181-7.

Rokos IC, French WJ, Koenig WJ, Stratton SJ, Nighswonger B, Strunk B, Jewell J, Mahmud E, Dunford JV, Hokanson J, Smith SW, Baran KW, Swor R, Berman A, Wilson BH, Aluko AO, Gross BW, Rostykus PS, Salvucci A, Dev V, McNally B, Manoukian SV, King SB 3rd…Phillips PS. Integration of pre-hospital electrocardiograms and ST-elevation myocardial infarction receiving center (SRC) networks: impact on Door-to-Balloon times across 10 independent regions. JACC Cardiovasc Interv. 2009 Apr;2(4):339-46.

Phillips PS,Haas RH. Statin Myopathy as a Metabolic Muscle Disease. Expert Rev Cardiovasc Ther 6(7),971-978 (2008).

Dao KHT, Shelton GD, Phillips PS. Dysregulation of nicotinic acetylcholine receptor expression in skeletal muscle – why patients with acquired denervation states are predisposed to succinylcholine-induced hyperkalemia and cardiac arrest. Under review, 2009..

Phillips PS, Ciaraldi TP, Kim DL, Verity MA, Wolfson T, Henry RR. Myotoxic Reactions to Lipid-lowering Therapy are Associated with Altered Oxidation of Fatty Acids. Endocrine 2009;35:38.

Phillips PS. Clinical Perspective of Statin-Induced Rhabdomyolysis-Letter. Am J Med 2007; 120:e33.

Hanai J, Cao P, Taksale P, Imamura S, Koshimizu E, Kishi S, Phillips PS, Lecker SH and Sukhatme VP. The muscle-specific ubiquitin ligase, atrogin-1/MAFbx mediates toxicity from HMG CoA reductase inhibitors. J Clin Invest. 2007;117:3940-51.

Kim DL, Ciaraldi TP, Carter L, Phillips PS, Henry RR. Common Actions of Pioglitazone and Lovastatin to Increase Free Fatty Acid Oxidation in Human Skeletal Muscle. Under review.

Phillips PS, Haas RH. Observations from a statin myopathy clinic [letter]. Archives Int Med 2006; 166;1232-1233.

Sikand H, Jaojoco J, Linares L, Phillips PS. Risk of Death With Atypical Antipsychotics [letter]. JAMA 2006;295:495-6.

Antons K, Williams C, Baker SK, Phillips PS. Clinical Perspectives of Statin-Induced Rhabdomyolysis. Am J Med 2006; 119:400-409.

Havranek JM, Wolfsen A, Warnke GA, Philips PS. Monotherapy with Ezetimibe Causing Myopathy. Am J Med 2006;119:285-286.

Phillips PS. How common is rhabdomyolysis in patients receiving lipid-lowering therapy? Invited Practice Point Commentary. Nat Clin Prac Card Med 2005; 2:130-131.

Vladutiu GD, Simmons Z, Isackson PJ, Tarnopolsky M, Peltier WL, Barboi AC, Sripathi N, Wortmann RL, Phillips PS. Genetic risk factors and metabolic myopathies associated with lipid-lowering drugs. Muscle & Nerve 2006; 34:153-162.

Phillips PS. Ezetimibe Muscle Toxicity [letter]. Ann Int Med 2004;141:649.

.

Phillips PS. Statin-Associated Myopathy is Associated with Impaired (-Oxidation of Fatty Acids. Mitomatters 2004; 3:3-4.

Phillips PS, Phillips CT, Sullivan M, Naviaux RK, Haas RH and the Scripps Mercy Clinical Research Center. Statin Myotoxicity is Associated with Changes in cardiopulmonary function. Atherosclerosis 2004;177:183-188.

Phillips PS, Haas RH, Bannykh S, Hathaway S, Gray NL, Kimura BJ, Vladutiu GD, England JDF and the Scripps Mercy Clinical Research Center. Statin Associated Myopathy with Normal Creatine Kinase. Ann Int Med 2002; 137:581-585.

Phillips P, Segovia J, Alfonso F, Goicolea J, Hernandez R, Banuelos C, Fernandez-Ortiz A, Perez-Vizcayno MJ, Kimura BJ, Macaya C. Advantage of Stents in the Most Proximal Left Anterior Descending Coronary Artery. Am Heart J 135:719-725 (1998).

Phillips P, Segovia J, Alfonso F, Goicolea J, Hernandez R, Banuelos C, Fernandez-Ortiz A, Perez-Vizcayno MJ, Macaya C. The Effects of Palmaz-Schatz Stents in Angled Coronary Arteries. Am J Cardiol 79:191-193 (1997).

Phillips P, Alfonso F, Segovia J, Goicolea J, Hernandez R, Banuelos C, Fernandez-Ortiz A, Perez-Vizcayno MJ, Macaya C. Characterization of a Precocious New Lesion Distal to a Stent site by Atherectomy. J Interven Cardiol 9:301-304(1996).

Arbab-Zadeh A, Blum RI, Phillips P, Kimura BJ. Intravascular Ultrasound Assessment and Endoluminal Stenting of a Stenosis in a 50-month old Coronary Ploytetrafluoroethylene Graft. J Invas Cardiol 13:xxx-xxx (2001)

Alfonso F, Rodriguez P, Phillips PS, Segovia J, Goicolea J, Hernandez R, Banuelos C, Fernandez-Ortiz A, Perez-Vizcayno MJ, Macaya C. Clinical and Angiographic Implications of Coronary Stenting in Thrombus-Containing Lesions. J Am Coll Cardiol 29:725-733 (1997).

Edep ME, Guarneri EM, Teirstein PS, Phillips PS, Brown DL. Differences in TIMI frame count following successful reperfusion with stenting or percutaneous transluminal coronary angioplasty for acute myocardial infarction. Am J Cardiol. 1999 May 1;83(9):1326-9.

Alfonso F, Fernandez-Ortiz A, Goicolea J, Hernandez R, Segovia J, Phillips PS,

Banuelos C, Macaya C. Angioscopic evaluation of angiographically complex coronary lesions. Am Heart J 134:703-711 (1997).

Alfonso F, Goicolea J, Hernandez R, Fernandez-Ortiz A, Segovia J, Aragoncillo P, Banuelos C, Phillips PS, Macaya C. Arterial Perforation During Optimization of Coronary Stents Using High-Pressure Balloon Inflations. Am J Cardiol 78:1169-1172 (1996).

Abstracts:

Saitoh A, Stani TM, Naviaux RK, Salva NG, Phillips PS, Haas RH. SIRT1 Activator Protects against Mitochondrial Toxicity Induced by Nucleoside Reverse Transcriptase Inhibitors in in vitro Models. 48th Annual ICAAC/IDSA 46th Annual Meeting. 10-27-8

Khachatryan A, Agan D, Sikand H, Phillips P. Evaluation of skeletal troponin-I as an early serum marker for statin-induced myopathies. Presented Amer Coll Clin Pharm 10-22-8 Louisville, KY.

Lim KS, Stan TM, Saitoh A, Naviaux RK, Phillips PS, Haas RH. Effect of Sirt1 Activation on Mitochondrial Diseases. Presented UMDF, 2008.

Lim KS, Stan TM, Saitoh A, Naviaux RK, Phillips PS, Haas RH. Effect of Sirt1 Activation on Heteroplasmy in Myotubes. Presented UMDF, 2008.

Strunk B et al. Nine Independent Regional STEMI Networks Exceed D2B Alliance Benchmark. ACC, 2008.

Moran R, Truong T, Wolfson T, McDonald FG, Phillips PS. Utility of cardiopulmonary exercise to assess myopathy [abstract]. Ath Thromb Vasc Biol; 2008, 28(6): e32.

Truong TH, Moran, R, Laaksonen R, Oresic M, Sukhatme VP, Lecker SH, Hohl RJ, Verity MA, Ciraldi TP, Schick BA, Cote HCF, Powell H, Davidson W, Wolfson T, Phillips PS [abstract]. Muscle Characteristics in Statin Myotoxicity [abstract]. J Amer Coll Cardiol 2008;51:A326.

Somma KA, Wolfsen TR, Arakelov S, Phillips PS. The Use of Skeletal Muscle Specific Troponin I as a Biomarker of Statin Induced Myopathy. Submitted AHA, 2006.

Linares LA, Jaojoco J, Phillips PS. Description of rhabdomyolysis in the statin era. Presented at Endocrine Society Meetings Boston, June, 2006.

Jaojoco J, Sikand H, Phillips PS. Defining rhabdomyolysis as an adverse drug event trigger for medication toxicity. Presented at Western States Pharmacy meetings. May, 2006.

Phillips PS, Gray NL, McDonald FG, Blaszcak M, Wolfson T, Sullivan MJ. Colesevelam HCl is Safe and Effective in Patients with Statin Myotoxicity. Arterioscler Thromb Vasc Biol 2005 25: e97.

Dong-Lim Kim, …Phillips PS. Actions of pioglitazone and a statin to increase free fatty acid oxidation in human skeletal muscle. Accepted for publication, 65th ADA Sessions, 2005.

Phillips PS, Ciaraldi TP, Dong-Lim K, Somma KA, Henry RR. Myotoxic Reactions to Lipid Lowering Therapies Are Mediated by Impaired Oxidation of Fats [abstract]. J Am Coll Cardiol 2005;45:413A.

Somma KA, Puhek LM, Gray NL, McDonald FG, Wolfson T, Phillips PS. Abnormal Fasting Respiratory Exchange Ratios Normalize Over Time in Patients With Statin-Induced Rhabdomyolysis or Myositis [abstract]. Arterioscler Thromb Vasc Biol 2005 25: e97.

Kordas KC, Phillips PS, Golomb BA. Clinical characteristics of 1053 patients with statin associated muscle complaints [abstract]. Arteriosclero Thromb Vasc Biol 2004;24:e51-e136.

Phillips CT, Gray NL, Puhek LM, McDonald FG, Sullivan MJ, Phillips PS. Cardiopulmonary Function Is Abnormal After Statin-Induced Rhabdomyolysis and Myositis [abstract]. J Am Coll Cardio 2004; 43 (suppl A):16a.

Phillips CT, Gray NL, Puhek LM, McDonald FG, Sullivan MJ, Phillips PS. Basal Respiratory Exchange Ratio Is Altered With Statin Use in Normals [abstract]. J Am Coll Cardio 2004; 43 (suppl A):233a.

Akhtar M, Peterson K, Phillips PS, Ben-Yehuda O. Dose titration of statins is an ineffective strategy in patients with poor response to initial starting dose [abstract]. J Am Coll Cardio 2004; 43 (suppl A):479a.

Todd Stephen Fergus, MD, Minh Bui, MD, Vachaspathy Palakodeti, MD,

Paul S. Phillips, MD. Closure of an Arteriocameral Fistula using a Polytetrafluoroethylene Covered Stent. Submitted J. Intervent Cardiol 10-2002.

Phillips PS, Kimura BJ, Kelley R, Thomas RG. Feasibility of using the internet to perform medical research: observations from a statin-myopathy public information web site. Circulation 2003;107:e7001-e7039.

Richard Haas, Bruce Barshop, Sergei Bannykh, Darius Amjadi, UCSD Medical Center, Paul Phillips, Scripps-Mercy Hospital Statin associated myopathy is associated with lipid accumulation and 3-methylglutaconic excretion[abstract]. Presented at Society for Inherited Metabolic Disease meeting in

Asilomar, CA 3-4-02.

Phillips PS, Haas RH, Barshop B, Bannykh S, Amjadi D. Utility of Abnormal 3-Methylglutaconic Aciduria (3MGA) in Diagnosing Statin Associated Myopathy. [abstract] Atheroscler Thromb Vasc Biol Online Journal 2002; 22:878.

Phillips P, Haas R, Bannykh S, Harminder N Sikand, Robert E. Pachorek, Bruce J Kimura, David M Stieber, Jeffery A Mullvain, Michael Sullivan, Nancy Gray, Stephanie Hathaway, John F England, Jerrold Glassman. HMG-CoA reductase inhibitor associated myopathy with normal creatine phosphokinase. Drugs Affecting Lipid Metabolism (DALM) Symposium. NYC 9-8-01

Phillips P, Alfonso F, Kimura BJ, Segovia J, Goicolea J, Hernandez R, Banuelos C, Fernandez-Ortiz A, Perez-Vizcayno MJ, Macaya C. Hinge point motion predicts restenosis for stents of markedly different design [abstract]. Am J Cardiol 82(suppl 7A):74s (1998).

Phillips P, Segovia J, Alfonso F, Segovia J, Goicolea J, Hernandez R, Banuelos C, Fernandez-Ortiz A, Perez-Vizcayno MJ, Macaya C. Implicaciones Clinicas y Angiograficas de la Implantacion de Stents de Palmaz-Schatz en Lesions en Curva [abstract]. Revista Cardiologia Espanol October, 1996.

Cortes J, Phillips P, Alfonso, Escaned J, Segovia J, Goicolea J, Hernandez R, Banuelos C, Fernandez-Ortiz A, Perez-Vizcayno MJ, Macaya C. Differences in restenosis in arterial segments with hinge motion points. Comparison of different stent designs. Eur J Cardiology August, 1999.

Segovia J, Phillips P, Alfonso F, Goicolea J, Hernandez R, Banuelos C, Fernandez-Ortiz A, Perez-Vizcayno MJ, Macaya C. Transcatheter therapy of proximal left anterior descending lesions: balloon angioplasty versus coronary stents [abstract]. Eur J Cardiol August, 1996.

Segovia J, Phillips P, Hernandez R, Alfonso, Escaned J, Goicolea J, Banuelos C, Fernandez-Ortiz A, Perez-Vizcayno MJ, Macaya C. . Restenosis after balloon angioplasty and coronary stenting of proximal left anterior descending lesions: a quantitative coronary analysis study [abstract]. J Am Coll Cardiol 29 (suppl A):497 A (1997).

Alfonso F, Rodriguez P, Phillips P, Segovia J, Goicolea J, Hernandez R, Banuelos C, Fernandez-Ortiz A, Perez-Vizcayno MJ, Macaya C. . Clinical and Angiographic Implications of Coronary Stenting in Thrombus-Containing Lesions [abstract]. J Am Coll Cardiol 29 (suppl A):96 A (1997).

Alfonso F, Martinez D, Goicolea J, Hernandez R, Segovia J, Fernandez-Ortiz A, Phillips P, Macaya C. Stent dislodgement with subsequent capture or embolization. A rare complication of coronary stenting [abstract]? Eur J Cardiol August, 1996.

Najar S, Alfonso F, Segovia J, Goicolea J, Hernandez R, Banuelos C, Phillips P, Fernandez-Ortiz A, Perez-Vizcayno M, Laudanno O, Macaya C. Stent de Cordis, experiencia inicial [abstract]. Revista Cardiologia Espanol , September 1996.

Azcona L, Alfonso F, Hernandez R, Segovia J, Banuelos C, Goicolea J, Phillips P, Najar S, Zarco P, Macaya C. Long-term survival of angioplasty patients with severe left ventricular dysfunction[abstract]. Eur J Cardiol August, 1996.

Alfonso F, Segovia J, Hernandez R, Goicolea J, Fernandez-Ortiz A, Banuelos C, Phillips P, Macaya C. Lesion characteristics in patients with recurrent ischemia after myocardial infarction: study with coronary angioscopy[abstract]. Circulation 94 (suppl I):I-255 (1996).

Arbab-Zadeh A, Blum R, Phillips PS, Kimura BJ. Intravascular ultrasound assessment and endoluminal stenting of a stenosis in a fifty month-old coronary polyetrafluoroethylene graft. Submitted to Catheterization and Cardiovascular Diagnosis (1998).

Russo RJ, Attubato MJ, Anderson WD, Bernstein R, Culp S, Davidson CJ, De Franco AC, Fitzgerald PJ, Goldberg S, Hermiller JB, Iaffaldano RA, Ling FS, Leon MB, Matar F, Mooney M, Phillips PS, Silva PD, Rocha-Singh K, Smith GJ, Smith S, Teirstein PS, Tobis J, Chiu Wong S, Weissman NJ, Zientek D, for the AVID Investigators. Angiography versus intravascular ultrasound-directed stent placement: final results from AVID.. Am J Cardiol 84 suppl 6A (1999)

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