Nutritional Epidemiology - Harvard University



VERSION 2 – UPDATED 12/3/2018 ID214 Nutritional EpidemiologySpring 2019Fridays, 9:45am-11:15am, Kresge Room 502Textbook: Willett, Nutritional Epidemiology, 3rd edition. (Also available online: )Course InstructorsWalter Willettdosulliv@hsph.harvard.eduDeirdre Tobiasdtobias@bwh.harvard.eduTeresa Fungtfung@hsph.harvard.eduTeaching AssistantsJiaxi Yangjiaxiyang@g.harvard.eduIbraheem Abioyeiaa551@g.harvard.eduYou Wuyow728@mail.harvard.eduOffice Hours:Tuesdays 1-2pm, Kresge 202AFeb. 1Overview of courseD. TobiasIntroduction to computer assignmentsOverview of nutrition epidemiologyW. WillettNature of variation in dietReadings:Chapters 1 and 3Beaton GH, et al. Sources of variance in 24-hour dietary recall data: implications for nutrition study design and interpretation. Am J Clin Nutr. 1979 Dec;32(12):2546-59. . 824-hour diet recall and food record methodsT. FungRemote recall of dietOverview of dietary assessment assignmentFFQ handed outReadings: Chapters 4 and 7Feb. 15Food frequency questionnairesW. WillettReproducibility and validity of food frequency questionnairesReadings: Chapters, 2, 5, 6, and 14Willett WC, et al. Reproducibility and validity of a semi-quantitative food frequency questionnaire. Am J Epidemiol. 1985 Jul;122(1):51-65. . 22Implications and analyses of total energy intake W. WillettReadings: Chapter 11Hu FB, et al. Dietary fat and coronary heart disease: a comparison of approaches for adjusting for total energy intake and modeling repeated dietary measurements. Am J Epidemiol. 1999 Mar 15;149(6):531-40. Mar. 1Homework #1 due in classHomework reviewTAsRandomized trials of dietary interventionsD. TobiasIssues in analysis and presentation of dietary dataReadings: Chapter 13Bernstein A, et al. Major dietary protein sources and risk of coronary heart disease in women. Circulation. 2010 Aug 31;122(9):876-83. Mar. 8Correction for measurement errorW. WillettReadings:Chapter 12Mar. 15IN-CLASS MIDTERM EXAMMar. 22SPRING BREAK – NO CLASSMar. 29Nutrient databaseT. Fung Apr. 5Anthropometric measures and body compositionD. TobiasReadings: Chapter 9Manson JE, et al. Body weight and longevity. A reassessment. JAMA. 1987 Jan 16;257(3):353-8. ? SH, et al. Body-mass index and mortality in Korean men and women. N Engl J Med. 2006 Aug 24;355(8):779-87. KF, et al. Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. N Engl J Med. 2006 Aug 24;355(8):763-78. Flegal KM, et al. Cause-specific excess deaths associated with underweight, overweight, and obesity. JAMA. 2007 Nov 7;298(17):2028-37? . 12Homework #2 due in classHomework reviewTAsDiet and heart diseaseF. HuReadings: Chapter 19Shekelle RB, et al. Diet, serum cholesterol, and death from coronary heart disease. The Western Electric study. N Engl J Med. 1981 Jan 8;304(2):65-70. Hu FB, et al. Dietary fat intake and the risk of coronary heart disease in women. N Engl J Med. 1997 Nov 20;337(21):1491-9. WC. Dietary fat plays a major role in obesity: no. Obes Rev. 2002 May;3(2):59-68. FB, Willett WC. Optimal diets for prevention of coronary heart disease. JAMA. 2002 Nov 27;288(20):2569-78. . 19Vitamin A and CancerW. WillettReadings: Chapter 17Hennekens CH, et al. Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med. 1996 May 2;334(18):1145-9. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med. 1994 Apr 14;330(15):1029-35. . 26Diet assessment due in classFolic acid, neural tube defects, and food fortificationW. WillettReadings: Chapter 20May 3Diet and breast cancerW. WillettReadings: Chapter 18Thiébaut AC, et al. Dietary fat and postmenopausal invasive breast cancer in the National Institutes of Health-AARP Diet and Health Study cohort. J Natl Cancer Inst. 2007 Mar 21;99(6):451-62. Prentice RL, et al. Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA. 2006 Feb 8;295(6):629-42. 10Review of the courseTAsMay 17IN CLASS FINAL EXAMINATION ................
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