An Examination of Penicillin Allergy

Of the 93 patients with negative skin tests who subsequently received penicillin, 5 (5.4%) had an adverse reaction – all to amoxicillin. However, 2 of the 5 patients subsequently tolerated 5 additional courses of penicillin (including amoxicillin) and 1 patient reacted only after her 4th course to penicillin. ................
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