Attachment: Extract from Clinical Evaluation Report ...

In the human abuse potential study, single doses of BRV 50 mg, 200 mg and 1000 mg were compared to alprazolam (1.5 mg and 3 mg). BRV showed fewer sedative, euphoric, stimulant, dizziness, and negative effects as compared to alprazolam; however, BRV was not significantly different from alprazolam on some measures of balance and positive effects ... ................
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