1: Gastro-intestinal system

Proton pump inhibitors should be used with caution in the elderly. There may be an association between PPI use & Clostridium difficile infection and osteoporosis. Careful consideration should be made to the risk benefit ratio. MHRA Drug Safety Update. Proton pump inhibitors in long-term use: Reports of hypomagnesaemia. Article date: April 2012 ... ................
................