Introduction to the ABO Blood Group - University of Utah

Introduction to the ABO Blood Group

Justin R. Rhees, M.S., MLS(ASCP)CM, SBBCM

Objectives

1. Describe the biochemistry and production of the A, B, and H antigens.

2. Compare and contrast the subgroups of the A and B blood types.

3. Describe two lectins that can be used to aid in correct ABO typing.

4. Given the results of forward and reverse ABO typing, correctly interpret the patient's ABO group and identify patterns of discrepancy.

ABO Typing

Anti-A Anti-B

Red blood cells

Hemagglutination

Anti-A: + Anti-B: 0

No Hemagglutination

A antigen detected

ABO Typing

Anti-A Anti-B

Anti-A: 0 Anti-B: 0

Neither A nor B antigens detected

ABO Typing

Anti-A: + Anti-B: +

A and B antigens detected

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