Mader/Biology, 10/e – Chapter Outlines
The RB tumor-suppressor gene prevents retinoblastoma, a cancer of the retina, and has been found to malfunction in cancers of the breast, prostate, bladder, and small-cell lung carcinoma. The p53 tumor-suppressor gene is more frequently mutated in human cancers than any other known gene; it normally functions to trigger cell cycle inhibitors ... ................
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