Nebraska ASAP | Antibiotic Stewardship Assessment ...



[Facility Logo]Antibiotic Susceptibility Report for Most Frequently Isolated Gram-Negative Organisms (January 2015 to December 2016)PathogenIsolate TestedPercent SusceptibleAmpicillinAmpicillin/SulbactamPiperacillin/TazobactamCefazolinCefepimeCefoxitinCeftazidimeCeftriaxoneCefuroximeAztreonamErtapenemMeropenemAmikacinGentamicinTobramycinCiprofloxacinLevofloxacinTrimethoprim/SulfaNitrofurantoin1TetracyclineEscherichia coli1115359998698929897919810010010091915859769977Klebsiella pneumoniae41--78989398959898939810010010098989595936383Proteus mirabilis419898100100100100100100100100100100100100757575755075Pseudomonas aeruginosa31----97--97--97----84--9010074777171-------- Denotes organism has intrinsic resistance to this antimicrobial1. Nitrofurantoin is reported for urine sources onlySummary for Gram-Negative OrganismsDuring the 2-year period between January 2015 and December 2016, a total of 111 E coli were identified, making it the most commonly identified Gram-negative pathogen. Antibiotic susceptibility of these E coli can be summarized as follow: Oral antibiotics with the highest susceptibilities (in descending order) were:Nitrofurantoin (99%)Cefuroxime (91%)Cephalexin (86%, as indicated by cefazolin susceptibility)Trimethoprim/sulfamethoxazole (76%) Susceptibilities of antibiotics available only in intravenous formulation (e.g., ceftriaxone) exceed 90%, except:Ampicillin/sulbactam (59%)Cefazolin (86%)Antibiotic susceptibility data can be useful for guiding selection of empiric antibiotic therapy for residents in whom culture and susceptibility data from the past few months are not available.Antibiotic Susceptibility Report for Most Frequently Isolated Gram-Positive Organisms (January 2015 to December 2016)PathogenIsolate Tested*Percent SusceptiblePenicillinAmpicillinOxacillin1GentamicinCiprofloxacin2Levofloxacin2MoxifloxacinTrimethoprim/SulfaClindamycin3Daptomycin4Nitrofurantoin5LinezolidVancomycinTetracycline2Staph. aureus (MSSA) 40%8----1001001313100100100100100100100100Staph. aureus (MRSA) 60%12----010088809260100100100100100Enterococcus faecalis4598100----6071------10010010010022* Antibiogram with <30 isolates are of questionable statistical significance; interpret data with caution-- Denotes organism has intrinsic resistance to or is not tested against this antibiotic1. Oxacillin predicts susceptibility to most cephalosporins, carbapenems, and beta-lactam/beta-lactamase inhibitors2. For E faecalis: ciprofloxacin, levofloxacin, tetracycline is reported for urine sources only3. For Staphylococcus species: clindamycin is reported for non-urine sources only4. For Staphylococcus species: daptomycin is reported for non-respiratory sources only5. Nitrofurantoin is reported for urine sources onlySummary for Gram-Positive OrganismsDuring the 2-year period between January 2015 and December 2016, a total of 45 E faecaisi were identified, making it the most commonly identified Gram-positive pathogen. Antibiotic susceptibility of these E faecalis can be summarized as follow: Oral antibiotics with the highest susceptibilities were:Ampicillin or amoxicillin (100%)Nitrofurantoin (100%)Linezolid (100%)Intravenous antibiotics with the highest susceptibilities were:Ampicillin (100%)Daptomycin (100%)Linezolid (100%)Vancomycin (100%)Antibiotic susceptibility data can be useful for guiding selection of empiric antibiotic therapy for residents in whom culture and susceptibility data from the past few months are not available. ................
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