Mayo Medical Laboratories
Mayo Medical Laboratories
Connective Tissue Diseases Cascade Test-Ordering Algorithm #1 (CTDC1)
Connective Tissue Diseases Cascade, Serum
-----------------------
Supports diagnosis of
Rheumatoid Arthritis
Antinuclear Antibodies (ANA), Serum
No further testing
< 1.0 U
Negative
( 20 Units
Cyclic Citrullinated Peptide Antibodies
( 1.0 U
(10 IU/mL
20 Units
CCP – Antibodies
(Order Separately – CCPB)
Supports diagnosis of lupus erythematosus
No further
testing
#83630 Antibodies to Extractable Nuclear Antigens, Reflex, Serum
Automatically performs the following tests
5-9 IU/mL
Indeterminate
#81357 Autoantibodies
to U1 RNP, Serum
#81358 Autoantibodies to Sm, Serum
#81360 Autoantibodies to SS-A/Ro, Serum
#81359 Autoantibodies to SS-B/La, Serum
#80178 Autoantibodies to Scl 70, Serum
#80179 Autoantibodies
to Jo 1, Serum
Positive result supports the diagnosis of Sjögren syndrome or other CTD*
Positive result supports the diagnosis of
lupus erythematosus*
Positive result supports the diagnosis of Sjögren syndrome or other CTD*
Positive result supports the diagnosis of mixed connective tissue disease*
Positive result supports the diagnosis of scleroderma*
Positive result supports the diagnosis of polymyositis*
* If negative, no further testing is performed.
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