Azilsartan National NME Drug Monograph
angiotensin II mediates its haemodynamic effects by binding to specific cell-surface receptors. In humans, two receptor subtypes have been identified, designated AT 1 and AT 2.Because all major deleterious effects of angiotensin II are produced via binding to AT 1-receptors, selective blockade of this receptor subtype should confer haemodynamic benefits, while allowing stimulation of the ... ................
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