Angiotensin Converting Enzyme 2: A Double-Edged Sword
leading to another pathway for ACE2 loss from SARS–CoV-2–induced systemic and tissue inflammation. In lung injury, deregulation of RAS through downregulation of ACE2 increases vascular permeability, pulmonary edema, and severity of injury in SARS-CoV infections though actions of angiotensin II that are attenuated by AT. 1. receptor blockade.. In postmortem … ................
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