Biochemistry Second Messengers
Angiotensin II action: Gq. Increases intracellular Ca2+ which activates CaM kinase. CaM kinase and PKC phosphorylate enzymes to increase the steroidogenic pathway, increasing aldosterone levels and Na+ reabsorption. PTH release: Inhibition by Ca2+ sensitive Gq . High Ca2+ inhibits PTH release by increasing intracellular calcium via IP3/DAG/Ca2+. ................
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