AusPAR Attachment 2: Extract from the Clinical Evaluation ...

Myfortic is an anti-proliferative immunosuppressant belonging to the anti-metabolite class of immunosuppressants. Mycophenolic acid (MPA), the active ingredient in Myfortic enteric coated tablets (EC-MPS), is a non-nucleoside, non-competitive, reversible inhibitor of inosine monophosphate dehydrogenase, which is the rate limiting enzyme in the de novo synthesis pathway of guanosine … ................
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