Antinuclear antibodies Raynaud's phenomenon: clinical ...
for the presence of antinuclear antibodies and for signs and symptoms of a connective tissue disease. Wealso assessed the diagnostic significance of the antigenic specificities ofthe autoantibodies. In addi-tion wedescribe the clinical spectrum of22patients with antinuclear antibodiesdirected against the cen-tromere region ofchromosomes. Materialsandmethods SUBJECTS ... ................
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