University of Alabama at Birmingham
Curriculum Vitae
Edward W. Inscho, Ph.D., FAHA, FAPS
Endowed Professor of Physiology
(Updated October 2, 2020)
UNIVERSITY ADDRESS: Division of Nephrology
Department of Medicine
840-B Kaul Building
The University of Alabama at Birmingham
720 20th Street, South
Birmingham, AL 35294
Phone: (205) 975-5841
FAX: (205) 975-7520
E-mail: einscho@uab.edu
HOME ADDRESS: 2405 ONeal Way
Birmingham AL 35242
Ph. (205) 538-5781
PERSONAL: Date of birth: July 25, 1954
Place of birth: Owego, New York
Citizenship: U.S.A.
Marital Status: Married: Carolyn Bill Inscho
Six children: Ryan, Alan, Brent, Mark, Emily and Jared
EDUCATION AND TRAINING:
1976 B.A. Biology major, Mercyhurst College, Erie, Pennsylvania,
Advisor: Sister Eymard Poydock, Ph.D.
1978 M.S., Biology and Experimental Medicine, Saint Thomas Research Institute (Formerly the Institutum Divi Thomae), Cincinnati, Ohio, Advisor: Leo G. Nutini, M.D.
1987 Ph.D., Physiology, University of Cincinnati College of Medicine; Cincinnati, Ohio,
Advisor: William W. Wilfinger, Ph.D.
1987-1988 Postdoctoral Fellow, Nephrology Research and Training Center; Department of Physiology and Biophysics, University of Alabama at Birmingham; Advisor: L. Gabriel Navar, Ph.D.
1988-1989 Postdoctoral Fellow, Department of Physiology; Tulane University School of Medicine,
Advisor: L. Gabriel Navar, Ph.D.
PROFESSIONAL EXPERIENCE:
1972-1976 Research Assistant, Biology and Cancer Research Laboratory, Mercyhurst College,
Erie, Pennsylvania
1976-1978 Graduate Research Assistant, Department of Biology, Saint Thomas Research Institute, Cincinnati, Ohio
PROFESSIONAL EXPERIENCE continued:
1978-1980 Laboratory Assistant, Department of Neurophysiology, Institute for Developmental Research, Cincinnati, Ohio
1980-1987 Graduate Research Assistant, Department of Physiology and Biophysics,
University of Cincinnati College of Medicine, Cincinnati, Ohio
1983-1986 Laboratory Instructor, Department of Physiology, University of Cincinnati College of Medicine, Cincinnati, Ohio
1984-1985 Medical Physiology Tutor, Department of Physiology,
University of Cincinnati College of Medicine, Cincinnati, Ohio
1988 Physiology Lecturer, Optometry Physiology, Renal Section,
University of Alabama at Birmingham, Birmingham, Alabama
1989-1991 Research Instructor, Department of Physiology,
Tulane University School of Medicine, New Orleans, Louisiana
1991-1992 Research Assistant Professor, Department of Physiology,
Tulane University School of Medicine, New Orleans, Louisiana
1992-1997 Assistant Professor, Department of Physiology,
Tulane University School of Medicine, New Orleans, Louisiana
1997-2000 Associate Professor, Department of Physiology,
Tulane University School of Medicine, New Orleans, Louisiana
2001-2014 Professor, Department of Physiology, Medical College of Georgia, Augusta, Georgia.
2001-2014 Professor of Graduate Studies, Medical College of Georgia, Augusta, Georgia.
2001-2010 Vice-Chairman, Department of Physiology, Medical College of Georgia, Augusta, Georgia
2001- 2014 Associate Member of the Vascular Biology Center, Medical College of Georgia, Augusta, Georgia
2005-2010 MD/PhD Program Director, Medical College of Georgia, Augusta, Georgia
2010-2014 Director of the American Heart Association Health Science Fellowship Program, Medical College of Georgia, Georgia Regents University, Augusta, Georgia.
2010-2012 Interim Dean of the School of Graduate Studies, Georgia Health Sciences University Georgia, Augusta, Georgia
Please Note: The Medical College of Georgia officially changed its name to Georgia Health Sciences University (GHSU) effective February 1, 2011 and the School of Medicine retained the name Medical College of Georgia. On January 9, 2013. Georgia Health Sciences University merged with Augusta State University and the new university was named Georgia Regents University (GRU) effective February 1, 2011. Georgia Regents University was renamed Augusta University effective September 1, 2015.
PROFESSIONAL EXPERIENCE continued:
2014-present Professor, Endowed Scholar, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
2014-present Professor, of Graduate Studies, University of Alabama at Birmingham, Birmingham, Alabama.
2014-present Professor, Nephrology Research and Training Center, University of Alabama at Birmingham, Birmingham, Alabama.
2019-present Professor, Stephen G. Rostand, MD, Endowed Professor of Nephrology, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
AWARDS AND HONORS:
1982, 1984 Federation of American Societies for Experimental Biology. Abstracts were selected as "particularly newsworthy" by the Science Editor.
1984-1987 Predoctoral Research Fellowship, NIH Training Grant, University of Cincinnati, Cincinnati, Ohio.
1984, 1985 University Research Council Travel Award, University of Cincinnati, Cincinnati, Ohio.
1984 Eckstein Memorial Fund Travel Award, University of Cincinnati, Cincinnati, Ohio.
1985 Who's Who Among Students in American Colleges and Universities, University of Cincinnati, Cincinnati, Ohio.
1987, 1988 NIH Training Grant, Postdoctoral Research Fellowship, University of Alabama at Birmingham, Birmingham, Alabama.
1989 American Heart Association Travel Award.
1992, 1993 Amgen Young Investigator Award for the National Kidney Foundation.
1993 American Physiological Society Travel Award, International Congress of Physiological Sciences.
1994-1999 NIH FIRST Award.
1995-2000 Established Investigator Award from the American Heart Association.
1996-present Fellow of the Council for High Blood Pressure Research of the American Heart Association.
1997 Distinguished Alumnus Award for Mercyhurst College.
1998 Owl Club Teaching Honor Role, Tulane University School of Medicine.
AWARDS AND HONORS continued:
1998 Harry Goldblatt Award in Cardiovascular Research from the American Heart Association Council for High Blood Pressure Research.
2000 Certificate of Recognition for participation in the School-to-Career Program for St. Charles Parish Public School System.
2000 American Society of Hypertension/Hoechst Marion Rousell Young Scholars Award from the American Society of Hypertension.
2000 American Physiological Society Travel Award to attend the joint meeting of the Scandinavian Physiological Society and American Physiological Society in Stockholm, Sweden.
2007 Medical College of Georgia Distinguished Service Award.
2008 Lewis K. Dahl Memorial Lecture; American Heart Association Council for High Blood Pressure Research.
2010 Medical College of Georgia Faculty Senate Distinguished Faculty Award for Basic Science Research.
2010 Medical College of Georgia Research Institute Distinguished Basic Research Award.
2011 Georgia Health Sciences University Exemplary Teachers Award.
2012 Charter member, Georgia Health Sciences University Chapter of the Phi Kappa Phi Honor Society.
2014 Mayerson-Di Luzio Award, Department of Physiology, Hypertension and Renal Center of Excellence, Tulane University Health Sciences Center, New Orleans, Louisiana. 4/7/2014.
2014 Selected for APSselect for distinction in scholarship in the American Journal of Physiology: Renal Physiology for our paper entitled “High Salt Diet Blunts Renal Autoregulation by a Reactive Oxygen Species-dependent Mechanism” by Fellner, Robert C., Anthony K. Cook, Paul M. O'Connor, Shali Zhang, David M. Pollock and Edward W. Inscho. This paper was also highlighted with an Editorial Focus commentary.
2014 Selected by the American Journal of Physiology: Renal Physiology to be featured in an AJP-Renal podcast based on our paper entitled “High Salt Diet Blunts Renal Autoregulation by a Reactive Oxygen Species-dependent Mechanism” by Fellner, Robert C., Anthony K. Cook, Paul M. O'Connor, Shali Zhang, David M. Pollock and Edward W. Inscho.
2016 Selected as a "Notable Mentor" in the UAB Department of Medicine, April 18-, 2016.
2017 Appointed as a Fellow of the American Physiological Society August 23, 2017.
2019 Inaugural holder of the Steven G Rostand, M.D. Endowed Professorship in Nephrology, April 18, 2019.
AWARDS AND HONORS continued:
2019 American Heart Association Volunteer Recognition Award June 1, 2019
2020 American Physiological Society Renal Section Gottschalk Lecturer
PREVIOUS GRANT SUPPORT:
American Heart Association Grant-in-Aid, La. Affiliate. Renal Microvascular Responsiveness to P1 and P2 Purinergic Stimulation: Adenosine vs. ATP. Principal Investigator. Total direct costs $18,500. Total project period 7/1/91 through 6/30/92.
American Heart Association Grant-in-Aid, La. Affiliate. Analysis of Renal Vascular Smooth Muscle Responses to ATP using Calcium Fluorescence. Principal Investigator. Total direct costs $3,000. Total project period 6/1/91 through 8/31/91.
Louisiana Education Quality Support Fund (LEQSF). Pathophysiology of Intracellular Ca2+ Homeostasis.
Co-Investigator, Edward W. Inscho, Total direct costs, $88, 755. Total project period 6/1/91 through 5/31/92.
American Heart Association Grant-in-Aid, La. Affiliate. Calcium Access Pathways Evoked by ATP-mediated Renal Microvascular Vasoconstriction. Principal Investigator, Total direct costs $20,000. Total project period 7/1/92 through 6/30/93.
National Kidney Foundation Young Investigator Grant. Purinergic Regulation of the Renal Microvasculature. Principal Investigator, Total direct costs $40,000. Total project period 7/1/92 through 6/30/94.
Louisiana Stimulus for Excellence in Research (LaSER) Competitive Grant. Integrative and Cellular Physiology of Vascular Control Mechanisms. Co-Investigator, Total direct costs $80,000. Total project period 6/1/94 through 5/31/95.
Louisiana Education Quality Support Fund (LEQSF). Integrative and Cellular Biology of Vascular Control Mechanisms. Co-Investigator, Total direct costs, $66,300. Total project period 6/1/94 through 5/31/95.
American Heart Association Grant-in-Aid, La. Affiliate. Mechanisms Involved in Agonist-Induced Elevation of Cytosolic Calcium in Renal Microvascular Smooth Muscle Cells. Principal Investigator, Total direct costs $20,000. Total project period 7/1/94 through 6/30/95.
NIH NIDDK 1R29DK44628. Purinergic Regulation of the Renal Microvasculature. Principal Investigator, Total costs $515, 011. Total direct costs $350, 000. Total project period 08/1/94 through 07/31/99.
American Heart Association Established Investigator Award #95001370. Purinergic Regulation of the Renal Microvasculature. Principal Investigator, Total direct costs $265,000. Total project period 7/1/95 through 6/30/2000.
Astra Hässle Grant. Influence of AT1 Receptor Blockade with Candesartan on the Autoregulatory Dysfunction that Accompanies Chronic Angiotensin II-induced Hypertension. Principal Investigator. Total direct costs $11,756.00. Total project period 03/5/97 through 03/04/98.
PREVIOUS GRANT SUPPORT continued:
NIH NHLBI 5 R01 HL058139-08. The Angiotensin II-Induced JAK/STAT Pathway in Diabetes. Principal Investigator, Mario Marrero. Edward W. Inscho, Co-Investigator, Total Project period: 04/01/97 through 03/31/06. Total costs $1, 148, 000. Total direct costs $1, 000, 000.
NIH NIDDK 5 P01 DK38226. Role of Eicosanoids in Renal Function. Principle Investigator, Jorge Capdevila, Vanderbilt University. This grant is for Project #4; Role of P450 Monooxygenases in Renal Hemodynamics. Total project period 11/01/98 through 10/30/03. Total costs $669, 477. Total direct costs $450,826. Principal Investigator on Project #4 is Dr. John D. Imig in the Vascular Biology Center at the Medical College of Georgia. Co-investigator on Project #4: Edward W. Inscho.
American Heart Association Southeastern Affiliate Grant-in-Aid (Award # 9950800V). Purinoceptor-dependent Regulation of Renal Microvascular Autoregulation. Principal Investigator, Total direct costs $70,000. Total project period 7/1/99 through 06/30/01 (This Louisiana Affiliate American Heart Association grant was declined when the National American Heart Association Grant-in-Aid was funded.)
American Heart Association Grant-in-Aid #9950513N. Renal Microvascular Responses to Endothelin. Principal Investigator, Total costs $165,000. Total direct costs $150,000. Total project period 7/1/99 through 6/30/02.
American Society of Nephrology Student Scholar Award entitled "The Role of P2 Receptor Function in Mediating Afferent Arteriolar Autoregulatory Behavior Resulting from Tubuloglomerular Feedback Mechanisms”. Principal Investigator, Total costs $31,200. Total direct costs $31,200. Total project period 6/1/00 through 5/31/01. This grant was approved but later declined when Mr. Steven White accepted a different academic position.
American Heart Association; Southeastern Affiliate Summer Research Fellowship entitled "Summer Research Fellowships in Cardiovascular Sciences”. Principal Investigator. Total direct costs $21,600.
Total project period 7/2/00 through 6/30/02. Oversight of this grant was turned over to another Tulane Faculty member when the P. I. moved to the Medical College of Georgia on January 1, 2001.
NIH NIA 1RO3AG18187. Renal Microvascular Function in Aged Rats. Principal Investigator, Total costs $74,250. Total Direct Costs $50,000. Total project period 04/01/00 through 03/31/01.
Astra Hässle Grant. Influence of AT1 Receptor Blockade with Candesartan on the Autoregulatory Dysfunction that Accompanies Chronic Angiotensin II-induced Hypertension. Principal Investigator. Total costs $42,867.00. Total direct costs $37,276.00. Total project period 7/00 through 6/03.
Juvenile Diabetes Foundation Regular Research Grant. The Role of TGF-beta on Afferent Arteriolar Dysfunction in Diabetes. Principal Investigator: Kumar Sharma M.D. from Thomas Jefferson Medical College. Co-investigator, (P. I. on the subcontract), Edward W. Inscho, Ph.D. Total costs $177, 369. Direct costs $161, 244. Total project period 7/00 through 6/03.
NIDDK 2 RO1 DK44628. Purinergic Regulation of the Renal Microvasculature. Principal Investigator, This project focuses on determining the physiological role of P2 receptors in the regulation of renal microvascular function. Total costs $921, 466. Total direct costs $628, 236. Total project period 2/1/00 through 2/28/04.
PREVIOUS GRANT SUPPORT continued:
NIH NHLBI RO1 HL59699 NIH Competitive Renewal. Oxygenase Metabolites and Renal Microvascular Reactivity. Principal Investigator, John D. Imig. Co-Investigator, Edward W. Inscho, Ph.D. The experiments outlined in this proposal address a provocative area of research defining the role of cytochrome P450 pathways in regulating preglomerular vascular function. Total costs $1, 260, 000. Direct costs $900, 000. Total project period 7/02 through 6/06.
NIH NHLBI 2 RO1 HL060653 Nitric Oxide and Endothelin Interactions in the Kidney. Principal Investigator, Jennifer Pollock. Co-Investigator, Edward W. Inscho, Ph.D. The experiments outlined in this proposal address the cellular and molecular mechanisms surrounding the interaction between the nitric oxide synthase and endothelin pathways in regulating the response to the renal inner medulla to high salt. Total costs $815, 302. Direct costs $550, 880. Total project period 07/01/03 through 06/30/08.
NIDDK 2 RO1 DK44628. Purinergic Regulation of the Renal Microvasculature. Principal Investigator. This project focuses on determining the physiological role of P2 receptors in the regulation of renal microvascular function. Total costs $1, 013, 613. Total direct costs $691, 060. Total project period 2/1/04 through 2/28/08.
NIH PO1 DK38226 Role of Eicosanoids in Renal Function; P. I. Jorge Capdevila, Vanderbilt University. This grant is for Project #4; Eicosanoids in Renal Microvascular Function. Total project period 07/01/04-06/30/09. Total direct costs $900,000. Total Costs $1, 287, 000. Principal Investigator on Project #4 is Dr. John D. Imig in the Vascular Biology Center at the Medical College of Georgia. Inscho is a Co-Investigator on Project #4.
NIH PO1 HL 074167-01. Cytokines and Angiotensin II-induced Hypertension. Principal Investigator, R. Clinton Webb. Project Three Leader, Edward W. Inscho, Mechanisms of Autoregulatory Impairment in Salt-sensitive Hypertension. Total project period 04/01/04 through 03/31/09. Total costs $1,380,552. Total direct costs $965, 421.
American Heart Association Predoctoral Fellowship Award: “Impairment of Renal Autoregulatory Behavior in Ang II Hypertension Involves Activation of P2Y12 Receptors”. Mentor for Mr. David Osmond. Total Project Period 7/1/2008 through 6/30/2010. Total costs $43, 540.
American Heart Association Postdoctoral Fellowship Award: “Preventing Impairment of Renal Autoregulation in Ang II-induced Hypertensive Rats”. Mentor for Dr. Zhengrong Guan. Total project period 7/1/2008 through 6/30/2010. Total costs $96, 476.
NIH NIDDK 2 RO1 DK044628-14. Purinergic Regulation of the Renal Microvasculature. Principal Investigator, 40% effort. Total costs $1, 561, 875. Total direct costs $1, 062, 500. Total project period 08/01/1994 through 03/31/2013. No Cost Extension in through 03/31/2016.
NIH NHLBI 1 RO1 HL098135-01. The Cytokines, MCP-1 and TGF-beta, Mediate Renal Autoregulatory Impairment. Principal Investigator: Edward W. Inscho 25% effort. Total costs $1,837,500. Total direct costs $1,250,000. Total project period 1/04/2010 through 12/31/2014. No Cost extension through 1/31/2016
American Heart Association Scientist Development Grant (National, 10SDG3770010): “Role of sphingosine-1-phosphate in regulating afferent arteriolar function and in hypertension induced renal injury”. Principal Investigator: Dr. Zhengrong Guan, Mentor: Edward W. Inscho. Total project period 7/01/2010 through 6/30/2014. Total costs $308,000.
PREVIOUS GRANT SUPPORT continued:
American Heart Association Health Sciences Fellowship Application. Advances in Cardiovascular, Diabetes and Obesity Research. Principal Investigator, Edward W. Inscho. Total Direct costs $27, 000. Total Program costs $29, 700. Project period 2/1/ 2011 through 1/31/2013.
American Heart Association Postdoctoral Fellowship 13POST14510007. High Salt Diet Blunts Renal Autoregulation Through Endothelin-dependent Reactive Oxygen Species Generation. Principal Investigator and Mentor for Dr. Robert Fellner. Total costs $104, 421.00. Total direct costs $94, 928.00. Total project period 01/01/2013 through 12/31/2014.
American Heart Association Health Sciences Fellowship Application. Advances in Cardiovascular, Diabetes and Obesity Research. Principal Investigator, Edward W. Inscho. Total direct costs $27, 000. Total program costs $29, 700. Project period 2/1/2013 through 1/31/2015.
American Heart Association Predoctoral Fellowship application. The Functional Role of TLR4 in the Renal Microvasculature Principal Investigator and graduate fellow, Justin Van Beusecum. Sponsor, Edward W. Inscho. Total direct costs $52,000.00. Total costs $57,200.00. Total project period 07/01/2014 through 6/30/2016.
UAB Nephrology Research and Training Center Anderson Innovation Award application entitled UAB Vascular PKD program. Principal Investigator and Project Leader for Project 2: Edward W. Inscho. (Co-Investigators: Project 1-David M. Pollock; Project 3- Bradley K. Yoder; Project 4- Michal Mrug). Total Program direct costs $60,000. Project period 2/1/2015 through 1/31/2016. The overall goal of this project is to conduct exploratory studies into the linkages between renal microvascular control, whole kidney renal hemodynamics and ciliary abnormalities in the genetics, development and progression to polycystic kidney disease. The program will employ novel models to: Project 1. Define pathobiology of systemic vascular responses in PKD; Project 2. Characterize etiology of intrarenal microvascular abnormalities in PKD; Project 3. Define role of primary cilia sensor in pathobiology of vascular responses in rat models of PKD; Project 4. Define role of immune responses in pathogenesis of PKD-related vascular effects during cyst initiation and progression. This grant was extended for 6 months to a new expiration date of 8/30/2016.
PO1 NIH Program Project Grant 1PO1 HL095499. Endothelin Control of Renal Hemodynamic and
Excretory Function. Principal Investigator, David M. Pollock. Project 2 Leader, Edward W. Inscho, 25% effort. Receptor Specific Mechanisms of Endothelin Control of the Renal Microcirculation. Total Project 2 direct costs $1,200,000. Total Program Project costs $11, 101, 752. Project period 8/6/2010 through 4/30/2015. No Cost extension.
American Heart Association Grant-in-Aid (Greater Southeast Research Affiliate, 15GRNT25240015): “Sphingosine-1-phosphate in ischemia-reperfusion induced renal microvascular injury”. Principal Investigator: Dr. Zhengrong Guan, Co-Investigator: Edward W. Inscho. Total project period 7/01/2015 through 6/30/2017. Total costs $165,000.
PKD Foundation Grant “Renal Vascular Function in ARPKD”. Principal Investigator, Edward W. Inscho 5% effort. Total Direct costs $160,000. Total costs requested $160,000. Project period 3/1/2016 through 2/28/2019.
American Physiological Society Undergraduate Summer Research Fellowship for Short-Term Research Education Program to Increase Diversity in Health-Related Research (STRIDE) awardees. Title “Inhibition of TLR4 activation in afferent arterioles prevents loss of autoregulatory function”. Principal Investigator, Brian Freeman; Mentor, Edward W. Inscho. Total costs $4, 000. Total direct costs $4, 000. Total project period 05/31/2018 through 08/5/2018
CURRENT GRANT SUPPORT:
American Heart Association Strategically Focused Hypertension Research Center entitled “Novel Mechanisms of Salt-sensitivity and Diurnal Blood Pressure Rhythm”. Principal Investigator for the Center: Paul, Muntner MD. (Co-Investigator of Project 3: Edward Inscho 20% effort, $200, 763/year). Total program direct costs $3, 709, 200. Project period 4/1/2015 through 3/30/2019. The overall goal of this project is to elucidate novel salt-dependent pathways leading to renal dysfunction and nocturnal hypertension with a non-dipping blood pressure phenotype. This project will integrate with a clinical project and a population project within the center.
PO1 NIH Program Project Grant 1PO1 HL136267. Integrating Novel Mechanisms Controlling Sodium Excretion and Blood Pressure. Principal Investigator, David M. Pollock. Co-Investigator Project 1 and 2 Edward W. Inscho, 20% effort. Total Program Project costs $11,263, 303. Project period 5/1/2017 to 3/31/2022.
NIH/NIDDK 1R01 DK106500-01. “Sphingosine-1-phosphate in renal microvascular dysfunction of ischemia-reperfusion kidney injury”. Principal Investigator, Zhengrong Guan. Co-Investigator, Edward W. Inscho, 5% effort. Total Project costs $1,424, 240. Total Direct costs $965, 616. Project period 7/18/2017 to 5/31/2021.
NIH NIDDK 2 RO1 DK044628-20. Competitive Renewal: TLR4 in the regulation of renal microvascular function. Principal Investigator, 35% effort. Total costs $2, 535, 630. Total direct costs $1, 707, 495. Total project period 08/01/1994 through 04/30/2022.
American Physiological Society Undergraduate Summer Research Fellowship for Short-Term Research Education Program to Increase Diversity in Health-Related Research (STRIDE) awardees. Title “Inhibition of TLR4 activation in afferent arterioles prevents loss of autoregulatory function”. Principal Investigator, Brian Freeman; Mentor, Edward W. Inscho. Total costs $4, 000. Total direct costs $4, 000. Total project period 05/31/2018 through 08/5/2018
NIH/NIDDK 1R13. “2019 APS Conference: Control of Renal Function in Health and Disease”. Principal Investigator, Edward W. Inscho. Co-Investigator, Pablo Ortiz, Proposed Total Project costs $15,000. Proposed Total Direct costs $15,000. Project period 6/1/2019 to 7/31/2019.
INVITED LECTURES AND SEMINARS: NATIONAL:
1986 Department of Physiology and Biophysics, Mayo Foundation, Rochester, Minnesota.
1986 Department of Physiology, University of Alabama at Birmingham, Birmingham, Alabama.
1986 Department of Cardiovascular Pharmacology, Smith, Kline and French, King of Prussia, Pennsylvania.
1986 Department of Physiology, University of North Carolina at Chapel Hill, Chapel Hill North Carolina.
1994 Department of Medical and Molecular Physiology, University of Minnesota at Duluth, Duluth, Minnesota.
1994 Department of Physiology, University of North Dakota, Grand Forks, North Dakota.
1995 Department of Pharmacology, Tulane University, New Orleans, Louisiana.
1995 Department of Anatomy, Tulane University, New Orleans, Louisiana.
1997 Department of Pharmacology, Louisiana State University School of Medicine, New Orleans, Louisiana.
1997. Vascular Biology Research Institute, Medical College of Georgia, Augusta, Georgia.
1997 Department of Pharmacology, Tulane University, New Orleans, Louisiana.
INVITED LECTURES AND SEMINARS: NATIONAL continued:
1997 Center for Clinical Pharmacology, Department of Medicine and Pharmacology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
1998 Vermont Summer Conference, Saxtons River, Vermont.
1999 Thomas Jefferson University School of Medicine, Philadelphia, Pennsylvania.
1998. Department of Physiology, University of Nebraska Medical Center, Omaha, Nebraska.
2000 Department of Physiology, University of South Alabama, Mobile, Alabama.
2000 Department of Cardiology, Tulane University School of Medicine, New Orleans, Louisiana.
2000 Department of Physiology and Endocrinology, Medical College of Georgia, Augusta, Georgia.
2000 Co-organizer and invited speaker of a symposium entitled "Extracellular ATP and cAMP as paracrine and inter-organ regulators of renal function" at the Experimental Biology 2000 meeting in San Diego, California. Talk entitled "Overview of P2 receptors and renal microvascular effects of P2 receptor stimulation”.
2000 Invited lecture entitled "P2 receptors in renal microvascular autoregulation" at the 15th Annual American Society of Hypertension meeting in New York, New York. Talk entitled "P2 receptors in renal microvascular autoregulation”.
2000 Center for Cardiovascular Sciences, Albany Medical Center, Albany, New York.
2000 Department of Physiology, West Virginia University School of Medicine, Morgantown, West Virginia.
2000 Invited presentation entitled P2X receptor blockade inhibits pressure-induced afferent arteriolar autoregulatory behavior in rat kidneys. at the Jackson Cardiovascular-Renal Meeting in Jackson, Mississippi.
2000 Department of Physiology, "P2 receptors in kidney: Then and now", Tulane University, New Orleans Louisiana.
2001 Invited Lecture entitled "What are purinergic receptors and what are their roles in the kidney?" Vermont Summer Conference, Saxtons River, Vermont.
2002 Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin.
2002 Cardiovascular Research Group, Morehouse School of Medicine, Atlanta, Georgia.
2002 Department of Medicine, University of Alabama at Birmingham "Mechanisms of renal microvascular control", Birmingham, Alabama.
2002 Department of Medicine, University of Alabama at Birmingham "Impairment of renal microvascular function in hypertension", Birmingham, Alabama.
2003 Invited speaker in a Symposium entitled “Regulation of renal function by extracellular nucleotides” at the American Society of Nephrology Annual Meeting in San Diego, CA. Talk entitled “Purinergic regulation of glomerular and renal microvascular function”.
2004 Cardiology Grand Rounds entitled “New insights into the mechanisms of renal microvascular autoregulation” at the Medical College of Georgia, Augusta, Georgia.
2004 Center for Interdisciplinary Research in Cardiovascular Sciences, West Virginia University, Morgantown, West Virginia. “New insights into the mechanisms of renal microvascular autoregulation”.
2004 Department of Physiology, Medical College of Georgia, Augusta Georgia. Seminar entitled “P2X1 receptors in renal microvascular autoregulation and tubuloglomerular feedback”.
2004 Department of Biology, University of Georgia, Athens Georgia. Seminar entitled Purinergic regulation of glomerular and renal microvascular function.
2004 Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston Texas. Seminar entitled "New insights into the mechanisms of renal microvascular autoregulation”.
INVITED LECTURES AND SEMINARS: NATIONAL continued:
2004 Department of Physiology, University of Mississippi Medical Center, Jackson Mississippi. Seminar entitled "P2X1 Receptors in renal microvascular autoregulation and tubuloglomerular feedback”.
2004 FASEB Summer Conference at Callaway Gardens in Pine Mountain, Georgia. Lecture entitled “Role of extracellular ATP in renal autoregulation”.
2004 University of Florida, Physiology and Functional Genomics, in Gainesville, Florida. Seminar entitled “Purinergic regulation of renal microvascular resistance"
2004 Mini-symposium at the University of Cincinnati, Department of Physiology and Biophysics. Talk entitled “New insights into the mechanisms of renal microvascular autoregulation”.
2004 Michigan State University, Department of Pharmacology and Toxicology in East Lansing Michigan. Talk entitled “New insights into the mechanisms of renal microvascular autoregulation”.
2005 Medical College of Georgia, School of Dentistry. Oral Biology Seminar Series March 16, 2005. Seminar entitled “P2X receptors in the regulation of microvascular function”
2005 Eastern Virginia Medical School. Department of Physiological Sciences April 24-26, 2005. Seminar entitled “The role of adenosine and ATP in mediating autoregulatory adjustments in preglomerular resistance”.
2005 Georgetown University School of Medicine, Department of Medicine May 5, 2005. Seminar entitled “The role of adenosine and ATP in mediating autoregulatory adjustments in preglomerular resistance”.
2005 Invited lecture at the Hypertension Summer School in Castine, Maine, July 17-20, 2005. Lecture entitled “Mechanisms of hypertension-induced renal injury”.
2005 Cardiology Grand Rounds at the Medical College of Georgia, October 31, 2005. Lecture entitled “Regulation of renal hemodynamics in hypertension”.
2005 Invited lecture in the Department of Physiology at the University of Arizona in Tucson AR, November 3, 2005. Lecture entitled “Purinergic mechanisms of renal microvascular autoregulation”.
2005 Invited lecture at the American Society of Nephrology Meeting in Philadelphia PA, November 9, 2005. Lecture entitled “Mechanisms of hypertension-induced renal injury”.
2005 Invited lecture in the Department of Pharmacology at the University of Tennessee at Memphis in Memphis TN. Seminar entitled “The role of adenosine and ATP in mediating autoregulatory adjustments in preglomerular resistance”.
2006 Invited lecture in the Department of Physiology at the University of North Dakota in Grand Forks, ND. February 17, 2006. Seminar Lecture entitled “Purinergic mechanisms of renal autoregulation in health and hypertension”.
2006. Invited lecture in the Department of Cellular and Integrative Physiology at the University of Nebraska in Omaha, NE, April 21, 2006. Seminar entitled “The impact of hypertension and inflammatory mediators on renal microvascular function”.
2006 Invited lecture in the Department of Physiology at the University of Southern California, in San Diego, CA, May 4, 2006. Seminar entitled “Purinergic mechanisms of renal autoregulation in health and hypertension”.
2006 Invited lecture to the University of Georgia Honors students, Athens, Georgia.
2006 Invited lecture in the Department of Biology and Geology, University of South Carolina Aiken, Aiken, South Carolina. September 22, 2006. Seminar entitled “Renal hemodynamics in hypertension and the relationship of inflammatory processes to hypertensive renal injury”.
2007 Symposium organizer with Bellamkonda K. Kishore for EB-2007. Symposium entitled “Emerging Insights into the Purinergic Signaling in Renal, Pulmonary and Microvascular Physiology and Pathophysiology”. Symposium talk entitled “Modification of renal microvascular purinergic signaling in hypertension”.
INVITED LECTURES AND SEMINARS: NATIONAL continued:
2007 Invited lecture at the Microcirculatory Society President’s Symposium April 28 at the EB 2007 meeting. Lecture title “Mechanisms of renal blood flow autoregulation”.
2007 Seminar on Scientific Misconduct Medical College of Georgia, Augusta, Georgia.
2007 Invited lecture in the Department of Medicine, University of California at San Diego, San Diego California. December 11, 2007. Seminar entitled “Renal autoregulation in normal and pathophysiological conditions”.
2008 Invited lecture in the Department of Physiology, Tulane University School, of Medicine, New Orleans, Louisiana. January 22, 2008. Seminar entitled “Renal vascular impairment in hypertension”.
2008 Medical College of Georgia, School of Dentistry, Augusta, Georgia. Oral Biology Seminar Series March 26, 2008. Seminar entitled “The impact of hypertension and inflammation on renal microvascular function”
2008 Hypertension and Vascular Research Division, Henry Ford Hospital September 5, 2008. Lecture entitled “the impact of hypertension and inflammation on renal microvascular function”.
2008 Lewis K. Dahl Memorial Lecture; American Heart Association Council for High Blood Pressure
Research. Lecture entitled “Mysteries of autoregulation”.
2008 Invited lecture in the Jackson Cardiovascular and Renal Meeting 2008 in Jackson Mississippi. October 17, 2008. Seminar entitled “A novel renal autacoid that influences renal microvascular function through P2X purinoceptor activation”.
2009 Invited lecture in the Department of Physiology and Biophysics at the University of Louisville, Louisville Kentucky, January 12, 2009. Seminar entitled “Mechanisms of renal microvascular dysfunction in hypertension”.
2009 Invited lecture in the Department of Pharmacology and Toxicology at Medical College of Virginia, Virginia Commonwealth, Richmond, Virginia, January 12, 2009. Seminar entitled “Mechanisms of renal microvascular dysfunction in hypertension”.
2009 Medical College of Georgia, Department of Physiology, Augusta, Georgia. Physiology Seminar Series March 19, 2009. Seminar entitled “A novel renal autocoid that influences renal microvascular function”.
2009 Medical College of Georgia, Division of Nephrology, Augusta, Georgia. Physiology Lecture Series November 24, 2009. Seminar entitled “Regulation of glomerular hemodynamics and renal blood flow”.
2010 Presidents Symposium organizer and Co-Chairman with William F. Jackson for EB-2010- Microcirculatory Society Symposium entitled “Hot Topics in Renal Microvascular Control”. Symposium talk entitled “Autoregulation and reactivity of afferent and efferent arterioles”.
2010 Invited lecture at the American Society of Nephrology meeting Basic and Clinical Science Symposium entitled “Regulation of Renal Function by Extracellular Nucleotides” November 18, 2010. Symposium talk entitled “Renal hemodynamics in hypertension and the relationship to hypertensive renal injury”.
2013 Invited lecture in the Division of Nephrology at the University of Alabama at Birmingham, Birmingham Alabama, April 15, 2013. Seminar entitled “Hypertension and renal stressors blunt renal autoregulatory behavior”.
2013 Invited lecture in the Department of Physiology at the University of Cincinnati, College of Medicine, Cincinnati, Ohio May 15, 2013. Seminar entitled “Wandering through autoregulation”.
2013 Invited lecture in the Department of Physiology at the University of Cincinnati, College of Medicine, Cincinnati, Ohio July 25, 2013. Seminar entitled “Hypertension and renal stressors in in the renal autoregulatory response”.
2014 Mayerson-Diluzio Award Lecture to the Tulane University Department of Physiology April 24, 2014. Lecture entitled “Understanding the Renal Microcirculation”.
INVITED LECTURES AND SEMINARS: NATIONAL continued:
2014 Invited Research Conference Presentation at Tulane University Department of Physiology April 24, 2014. Lecture entitled “Acute Activation of Toll-like Receptor 4 by Lipopolysaccharide (LPS) Blunts Afferent Arteriole Autoregulatory Behavior”.
2014 Invited speaker for a special NIH-sponsored (NINDS and NHLBI) workshop entitled: “Small
Blood Vessels: Big Health Problems?” held in Bethesda, MD September 18-19, 2014. Spoke on the “Role of the renal microcirculation in controlling renal hemodynamics and in renal injury”.
2014 Invited lecture to the UAB Polycystic Kidney group October 22, 2014. Lecture entitled “Understanding the renal microcirculation”.
2015 Invited lecture to the UAB Center for Free Radical Biology March 11, 2015. Lecture entitled “Influence of inflammation and reactive oxygen species on renal microvascular function”.
2015 Invited lecture to the UAB Vascular Biology and Hypertension Program, March 20, 2015. Lecture entitled “Inflammatory processes blunt renal microvascular autoregulatory efficiency”.
2017 Invited lecture to the Tulane University Department of Physiology, November 6, 2017. Lecture entitled “The influence of toll-like receptor 4 on renal microvascular function”.
2017 Invited Research Conference Presentation at Tulane University Department of Physiology November 6, 2017. Presentation entitled “Recent work in the role of sphingosine-1-phosphate in renal microvascular function
2019 Invited Research Conference Presentation at University of the Mississippi Medical Center, Department of Physiology January 9-10 2019. Presentation entitled “The Influence of Toll-Like Receptor 4 on Renal Microvascular Function”.
2019 Invited Research Nephrology Research and Training Center Conference at the University of Alabama at Birmingham, Division of Nephrology April 22, 2019. Presentation entitled “TLR4 in the Regulation of Renal Microvascular Function”.
2020 Invited lecture for the 31st Vascular Biology and Hypertension Symposium at the University of Alabama at Birmingham June 18 and 19, 2020.
2021 Invited lecture for the 31st Vascular Biology and Hypertension Symposium at the University of Alabama at Birmingham Rescheduled for 2021 due to COVID-19 shutdown.
INVITED LECTURES, SEMINARS AND PRESENTATIONS: INTERNATIONAL:
1996 Invited speaker to the International Society of Hypertension Satellite Symposium on "The role of adenosine and ATP in the cardiovascular system". Talk entitled “Purinoceptor-mediated regulation of renal microvascular function”. Freiburg, Germany.
1996 Co-chairman of the “Purines and renal function” session of the International Society of Hypertension Satellite Symposium in Freiburg, Germany.
1998 Invited speaker to the workshop on "Function and clinical perspectives of angiotensin AT1 receptors: cardiovascular and renal function in health and disease"; Budapest, Hungary.
1999 Fourth U.S.-Japan workshop on “Molecular and cellular aspects of vascular smooth muscle function”, May 11-15 in Honolulu, Hawaii.
2000 Invited presenter at the workshop on "Angiotensin II receptor blockade: effects beyond blood pressure control"; Prague, Czech Republic.
2000 Selected talk entitled “P2X1 receptor blockade inhibits pressure-induced afferent arteriolar autoregulatory behavior in rat kidneys” at the Joint meeting of the Scandinavian Physiological Society and American Physiological Society in Stockholm, Sweden.
2002 Session Chairman for Purines in the Renal and GI systems at the 7th International Symposium for Adenosine and Adenine Nucleotides in Gold Coast, Queensland, Australia.
2002 Selected talks entitled "P2 receptors mediate pressure-induced afferent arteriolar autoregulatory behavior”. and "Calcium signaling mechanisms in the regulation of afferent arteriolar function" at the 4th International Congress of Pathophysiology, Budapest, Hungary.
INVITED LECTURES, SEMINARS AND PRESENTATIONS: INTERNATIONAL continued:
2002 Co-chairman of the symposium on Integration of Endocrine, Paracrine and Novel Messengers in Cardiovascular Disease at the 4th International Congress of Pathophysiology, Budapest, Hungary.
2003 Invited speaker to the 10th Acta Physiologica Scandinavica Symposium on the Functional Genomics of the Juxtaglomerular Apparatus. Talk entitled “Renal autoregulation in P2X1 knockout mice“, Odense, Denmark.
2004 Invited speaker for the Physiological Society Symposium entitled Purines, adenosine and nitric oxide in the regulation of kidney function. Talk entitled “The role of purinergic receptors along the renal microvasculature“, Cork, Ireland.
2006 Invited speaker for the Canadian Society of Nephrology Annual meeting in Quebec City, May 26, 2006, Quebec Canada. Lecture entitled “Renal hemodynamics in hypertension and the relationship to hypertensive renal injury” given in a session entitled “Hypertension and the role of the kidney”.
2006 Invited speaker for the 11th International Symposium on Vascular Neuroeffector Mechanisms and Cardiovascular Pharmacology and Medicine meeting in Suzhou China, June 27, 2006. Lecture entitled “Role of P2X receptors in autoregulation of renal blood flow” given in a session entitled “Myogenic tone and autoregulation”.
2008 Invited speaker for the Purines 2008 Conference in Copenhagen, Denmark, June 29- July 2, 2008. Lecture entitled “P2Y12 receptor blockade or anti-inflammatory treatment preserves renal microvascular function in hypertension”.
2010 Invited speaker for the Purines 2010 Conference in Tarragona, Spain May 30 – June 2, 2010. Lecture entitled “Hypertension and renal stressors blunt renal microvascular autoregulatory behavior by reducing renal microvascular reactivity to P2X1 receptor activation”. Co-Chair along with Imogen Coe of the conference session entitled “Purinergic signaling in the cardiovascular system”.
2011 Invited speaker for the FESBE, Federação de Sociedades de Biologia Experimental in Rio de Janeiro from August 24 through 28, 2011. Lecture entitled “ATP is not just for energy anymore” in a symposium entitled “New Frontiers of Renal Function”.
2014 Invited speaker for the Swedish Physiological Society meeting.
2015 Invited lecture at the Texas A&M in Temple, Texas, July 29 and 30, 2015. Lecture entitled “Impact of inflammation on renal autoregulation and renal microvascular function”.
GRANT REVIEWS AND STUDY SECTIONS:
1995-2000 Veterans Administration
1997 American Heart Association, Louisiana Affiliate, Research Peer Review Committee
1998 National Kidney Foundation of Michigan, Inc. Peer Review Committee
1998 National Institutes of Health; Natl. Inst. Gen. Med. Sci.; MBRS Physiology Review Panel.
1998-2002 American Heart Association Southern Research Consortium; Research Peer Review Committee 3
1999-2000 Partners in TIME: Teaching and Learning Innovations in Medical Education Mini-Grants Review Committee
2000 Jewish Hospital Foundation, Louisville, Kentucky
2002-2003 National Institutes of Health; Cardiovascular and Renal (CVB) Study Section, Ad-Hoc Reviewer
2002-2004 Co-Chairman of Research Peer-Review Committee 3, American Heart Association Southern Research Consortium
2003 National Institutes of Health; Program Project Grant Review Committee, Ad-Hoc Reviewer
2003 National Institutes of Health; Cardiovascular and Renal (CVB) Study Section, Regular Member
GRANT REVIEWS AND STUDY SECTIONS continued:
2004 National Institutes of Health; ZRG1 CVSA02 Special Emphasis Panel, Ad Hoc reviewer
2004-2008 National Institutes of Health; Hypertension and Microcirculation (HM) Study Section, Regular Member
2004-2006 Chairman of Research Peer-Review Committee 3, American Heart Association Southern Research Consortium
2004. National Institutes of Health; ZRG1 CVSB02 Special Emphasis Panel, Ad Hoc Reviewer
2005. National Institutes of Health; ZRG1-CVS-G Special Emphasis Panel, Ad Hoc Reviewer
2005 Arizona Disease Control Research Commission, Ad Hoc Reviewer
2005 National Institutes of Health; ZRG1 CVSD90 Special Emphasis Panel, Ad Hoc Reviewer
2005 National Institutes of Health; ZRG1-HM-G Special Emphasis Panel, Ad Hoc Reviewer
2006 National Institutes of Health; ZRG1-HM-D-03 Special Emphasis Panel, Ad Hoc Reviewer
2006-2008 Chairman of the National Institutes of Health; Hypertension and Microcirculation (HM) Study Section
2006 National Institutes of Health; Program Project Grant Review Committee, Ad-Hoc Reviewer
2006 Intramural Grants Program Review Committee, Medical College of Georgia Research Institute
2007 National Institutes of Health; Program Project Grant Review Committee, Ad-Hoc Reviewer
2007 National Institutes of Health; ZRG1-HM-D-02S Special Emphasis Panel, Ad Hoc Reviewer
2008 National Institutes of Health; Program Project Grant Review Committee ZHL1 PPG-A (O1), Ad-Hoc Reviewer
2008 National Institutes of Health; Program Project Grant Review Committee ZHL1 SRC(99), Ad-Hoc Reviewer
2008 National Institutes of Health; Program Project Grant Review Committee ZHL1, Ad-Hoc Reviewer
2008 National Institutes of Health; ZRG-1CVS-C(02) Special Emphasis Panel, Ad Hoc Reviewer
2009 National Institutes of Health; ZRG1 VH-D (58)R Challenge Grant Special Emphasis Panel, Ad Hoc Reviewer, July 20-21, 2009
2009 National Institutes of Health; ZRG1-VH-B-03 Special Emphasis Panel, Ad Hoc Reviewer
2009 National Institutes of Health; ZRG-1CVS-C(02) Special Emphasis Panel, Ad Hoc Reviewer
2010 National Institutes of Health; ZRG-1 VH-A 02 Special Emphasis Panel, Ad Hoc Reviewer
2010 National Institutes of Health; ZRG-1 VH-D 55R Special Emphasis Panel, Ad Hoc Reviewer
2010 National Institutes of Health; Hypertension and Microcirculation (HM) Study Section, Ad hoc reviewer October 11-12, 2010 meeting
2011 National Institutes of Health; Program Project Grant Review Committee workgroup 2, Ad-hoc reviewer
2012 National Institutes of Health; Program Project Grant Review Committee Scientific Review Group 2012/10 HLBP 1
2013 National Institutes of Health; Special Emphasis Panel Reviewer for ZRG1 VH-D (50) R - PAR Panel: NHLBI Systems Biology
2013 American Heart Association/Suncoast Cardiovascular Research and Education Foundation, Ad Hoc Reviewer
2013 National Institutes of Health; Special Emphasis Panel Reviewer for 2013/10 ZRG1 VH-B (02) meeting: Vascular Hematology
GRANT REVIEWS AND STUDY SECTIONS continued:
2013 Chairman of the National Institutes of Health; NHLBI Special Emphasis Panel Reviewer for 2013/10 ZHL1 PPG-G (01) 1, Ad Hoc Grant Reviewer
2013 National Institutes of Health; Program Project Grant Review Committee Scientific Review Group 2014/01 HLBP 20-1
2013 National Institutes of Health; Program Project Grant Review Committee Scientific Review NHLBI-[E]
2013 National Institutes of Health; Hypertension and Microcirculation (HM) Study Section, Ad hoc reviewer December 19, 2013 meeting.
2013 National Institutes of Health, Ad hoc reviewer for Special Emphasis Panel (SEP), ZRG1HM-B(02)S, December 19, 2013.
2014 National Institutes of Health; Program Project Grant Review Committee Scientific Review NHLBI-HLBP.
2014 National Institutes of Health, Ad hoc reviewer for Special Emphasis Panel (SEP), Special Emphasis Panel/Scientific Review Group 2015/01 ZRG1 VH-B (03) S. December 15, 2014.
2015 National Institutes of Health, Ad hoc reviewer for Special Emphasis Panel (SEP), Special Emphasis Panel/Scientific Review Group Special Emphasis Panel/Scientific Review Group 2015/10 HLBP 1 meeting, April 16, 2015.
2015 AHA Study Section in Dallas, TX for review of Established Investigator applications October 20, 2015
2016 Intramural Grant Review for the UAB Department of Medicine Research Development Group for Dr. Bhupesh Panwar and his NIH K23 application, September 19, 2016.
2016 AHA Study Section on Cardiorenal 2. Teleconference held 4/11/2016.
2016 AHA Study Section in Dallas, TX for review of Established Investigator Award applications October 27-28, 2016
2017 Intramural Grant Review for the UAB CCTS for Dr. Eman Gohar and her AHA Career Development grant, January 19, 2017.
2017 Intramural Grant Review for the UAB Department of Medicine Research Development Group for Dr. Carmen De Miguel and her NIDDK Mentored Research Scientist Development Award (K01), February 24, 2017.
2017 Intramural UAB SMART Review for an NIH F30 application prepared by Mark Peppin on March 14, 2017
2017 Intramural Grant Review for the UAB Department of Medicine Research Development Group for Dr. Guangli Cheng and his UAB Bridge funding application, May 12, 2017.
2017 Intramural Grant Review for the UAB CCTS for Dr. Wenguang “Stanley” Feng and his NIH RO1 application, May 15, 2017.
2017 Intramural Grant Review for the UAB CCTS for Dr. Wenguang “Stanley” Feng and his NIH RO1 application, September 7, 2017.
2017 Co-Chairman of the AHA Study Section for review of Established Investigator Award applications in Dallas, TX, November 29-30, 2017.
2018 Intramural Grant Review for the UAB Department of Medicine Research Development Group for Dr. Malgorzata Kasztan and her K99 application, January 30, 2018.
2018 Intramural Grant Review for the UAB Department of Medicine Research Development Group for Dr. Carmen De Miguel and her NHLBI KO1 application, January31, 2018.
2018 National Institutes of Health, NIDDK; Program Project Grant Review Committee Special Emphasis Panel ZDK1 GRB-S (O4). May 09, 2018.
2018 NIDDK Diabetes Complications Consortium (DiaComp) Study Section to review Pilot and Feasibility grant applications by August 24, 2018.
GRANT REVIEWS AND STUDY SECTIONS continued:
2018-19 Chairman of the AHA Study Section for review of Established Investigator Award applications in Dallas, TX.
2019 Member of the Special Emphasis Panel/Scientific Review Group 2020/01 ZRG1 F10C-A (20) L study section to review Physiology and Pathobiology of the Vascular and Hematological Systems fellowship applications November 6, 2019.
2020 American Heart Association grant reviewer for Rapid Response Grants on COVID-10 and it Impact on the Cardiovascular and Cerebrovascular Systems. April 8-16 2020.
AD HOC MANUSCRIPT REVIEWS:
|Acta Physiologica Scandinavica |Microcirculation. |
|American Journal of Kidney Diseases |Mineral and Electrolyte Metabolism |
|American Journal of Pathophysiology |Mini Reviews on Medicinal Chemistry |
|American Journal of Physiology: Renal Physiology |Nature-Medicine |
|American Journal of Physiology: Heart and Circulatory Physiology |Nephrology Dialysis Transplantation |
|American Journal of Physiology: Regulatory, Integrative and |Nephron |
|Comparative Physiology | |
|American Journal of Physiology: Cell Physiology |News in Physiological Sciences |
|American Journal of Hypertension |Journal of the American Heart Association |
|Arteriosclerosis, Thrombosis and Vascular Biology | |
|BioChimica et BioPhysica Acta |Journal of the American Society of Nephrology |
|Biomed Central |Journal of Applied Physiology |
|British Journal of Pharmacology |Journal of Cardiovascular Pharmacology |
|Canadian Journal of Physiology and Pharmacology |Journal of Clinical Investigation |
|Clinical Science |Journal of Hypertension |
|Clinical and Experimental Hypertension |Journal of Molecular Medicine |
|Clinical & Experimental Pharmacology and Physiology |Journal of Human Hypertension |
|Circulation Research |Journal of Pathophysiology |
|Diabetologia |Journal of Pharmacology and Experimental Therapeutics |
|Endocrinology |Journal of Physiology and Biochemistry |
|Experimental Biology and Medicine |Journal of Vascular Research |
|Free Radical Biology |Journal of Visual Experiments (JoVE) |
|Frontiers in Cardiovascular Medicine |Open Urolology and Nephrology |
|Frontiers in Endocrinology | |
|Hypertension | |
|International Journal of Cardiology |Pflugers Archives - European Journal of Physiology |
|International J. of Cardiology: Metabolic & Endocrine |Pharmacological Research |
|International J. of Cardiology: Heart Vessels |Physiological Reports |
|Kidney and Blood Pressure Research |Proceedings for the Society of Experimental Biology and Medicine |
|Kidney International |Purinergic Signalling |
|Life Sciences |The Open Urology and Nephrology Journal |
| |Vascular Pharmacology (General Pharmacology |
EDITORIAL BOARDS:
2001-2014 American Journal of Physiology: Renal Physiology
2001-2013 Clinical Science Advisory Panel
2003-2015 Hypertension (Term ended September 30, 2015)
2003-2006 Member of the Publications Committee, AHA Council for High Blood Pressure Research
2004-2012 Current Hypertension Reviews
2007-present The Open Cardiovascular Medicine Journal
2008-present The Open Urology & Nephrology Journal
2010-2014 Clinical and Experimental Pharmacology and Physiology
2014-present Frontiers in Cardiovascular Medicine, Hypertension
2020-present American Journal of Physiology: Renal Physiology
SOCIETY MEMBERSHIPS:
1987-present American Heart Association, Council on Kidney and Cardiovascular Disease
1990-present American Physiological Society
1996-present American Heart Association, Council on High Blood Pressure Research
1995-present American Society of Nephrology
1997-present Microcirculatory Society
1999-2000 Gulf Coast Physiological Society
2000-2006 American Society of Hypertension
2001-2003 Carolina and Georgia Society of Hypertension
2002-2003 Scientists Center for Animal Welfare
2007-2010 National Kidney Foundation
EXTRAMURAL COMMITTEES AND SERVICE:
1997-2004 Excellence in Renal Research Award Committee; Judge
1999 Co-organizer of the Central Gulf States Physiological Society Chapter of the American Physiological Society
1999-2013 Ad Hoc abstract grading consultant for the American Heart Association Council for High Blood Pressure Research
1999-2000 Secretary Treasurer of the Central Gulf States Physiological Society Chapter of the American Physiological Society
1999-2000 Co-organizer of a symposium entitled "Extracellular ATP and cAMP as paracrine and inter-organ regulators of renal function" convened at the Experimental Biology 2000 meeting in San Diego, California
2000 Ad Hoc abstract grading consultant for the 18th Scientific Meeting of the International Society of Hypertension (ISH 2000), Chicago, IL
2000 American Physiological Society Renal Section Steering Committee Member
2001-2002 Co-Chair of the Excellence in Renal Research Award Committee for Renal Section of the American Physiological Society
2001 Member of the Program Committee for the 55th Conference of the American Heart Association Council for High Blood Pressure Research, Orlando, FL
2002-2004 Chairman of the Excellence in Renal Research Award Committee for Renal Section of the American Physiological Society
2002 Presenter at the Science Education Outreach Session sponsored by the American Physiological Society; Directed by Dr. Jeffrey Osborne: EB 2002, New Orleans, LA
2002 Chairman for the Renal Transport and Pathophysiology Session at the 56th Council for High Blood Pressure Research Meeting in Orlando, Fla
EXTRAMURAL COMMITTEES AND SERVICE continued:
2002-2012 Ad Hoc abstract grading consultant for the American Heart Association Scientific Sessions
2005. Member of the Membership Committee for the American Physiological Society
2006. Chairman of the Trainee Session for the AHA Council for High Blood Pressure Research
2007-2010 Member of the American Heart Association Greater Southeast Affiliate Research Committee
2007-present American Heart Association Science Classification Task Force
2007-present American Heart Association Region 2 Steering Committee
2007-2010 Member of the American Heart Association Fall Conference Program Committee for the Council for High Blood Pressure Research.
2009-present American Heart Association Southeast Affiliate Research Committee Representative to the Task Force Examining Pros and Cons of Unified Peer Review
2009-2010 American Heart Association Unified Peer Review Steering Committee Pilot program
2009-2012 North American Chapter of the Purine Club Organizing Committee
2010-2012 Member of the American Heart Association Council for High Blood Pressure Research Awards Committee
2010-2012 Chairman of the American Heart Association Southeast Affiliate Research Committee
2010-2012 Member of the American Heart Association Southeast Affiliate Board of Directors
2010-2012 Member-at-large of the Leadership Committee for the American Heart Association Council on High Blood Pressure Research
2012-2014 Member of the American Physiological Society Conference Committee (Exp 12/31/2014)
2012 Invited participant in the American Heart Association Research Summit
2012-2014 American Heart Association Council for High Blood Pressure Research Leadership Committee Member at Large (Exp. 10/30/14)
2014 Ad Hoc abstract grading consultant for the Joint Meeting ESH-ISH Hypertension 2014, meeting to be held in Athens, Greece from June 13-16, 2014.
2015-2019 Joint Programming Committee Representative for the Renal Section of the American Physiological Society. 1/1/16 through 4/10/19.
2015-2019 Member of the American Physiological Society Renal Section Young Investigator Award Committee and the New Investigator Award Committee
2015-2019 Member of the American Physiological Society Renal Section Steering Committee
2017 Ad Hoc abstract grading consultant for the American Society of Nephrology meeting to be held in New Orleans La, Nov1-5, 2017.
2017-2019 Chair of the Organizing Committee for the 2019 APS/ASN Summer Conference entitled “Control of Renal Function in Health and Disease” held June 23-27, 2019 in Charlottesville VA. .
2017-2022 Member of the American Heart Association Council on Hypertension Awards Committee 12/1/17 thorough 06/30/2022.
TULANE UNIVERSITY FACULTY AFFILIATIONS:
1989-2000 Physiology Faculty
1992-2000 Molecular and Cell Biology Faculty
1994-2000 Member of the Graduate Faculty
GEORGIA REGENTS UNIVERSITY FACULTY AFFILIATIONS
2001-2014 Physiology Faculty
2001-2014 Member of the Graduate Faculty
2001-2014 Associate Member of the Vascular Biology Center
UNIVERSITY OF ALABAMA AT BIRMINGHAM FACULTY AFFILIATIONS
2014-present Division of Nephrology, Department of Medicine Faculty
2014-present Member of the Nephrology Research and Training Center
GRADUATE STUDENT AND POSTDOCTORAL TEACHING EXPERIENCE:
1985 and 1986 Laboratory and Tutorial Assistant, Medical Physiology, College of Medicine,
University of Cincinnati
1988 Lecturer, Renal Physiology, School of Medicine, Optometry Students, University of Alabama at Birmingham
TEACHING EXPERIENCE AT TULANE UNIVERSITY:
1989-2000 Laboratory Instructor, Medical Physiology, School of Medicine, Tulane University
1992-2000 Lecturer, Physiology of Body Fluids, School of Medicine, Tulane University
1993-2000 Lecturer, Advanced Topics in Renal Physiology, School of Medicine, Tulane University
1993-1998 Director of the Renal and Vascular Workshop
1994, 1997 Graduate Student Workshop, School of Medicine, Tulane University
1994 Associate Course Director, Medical Physiology, School of Medicine, Tulane University
1994-2000 Lecturer, Medical Physiology, School of Medicine, Tulane University
1995-2000 Lecturer, Advanced Topics in Cardiovascular Pharmacology, School of Medicine,
Tulane University
1996-2000 Course Director, Advanced Topics in Microvascular Physiology, School of Medicine,
Tulane University
1997-2000 Lecturer, Summer Medical Physiology, School of Medicine, Tulane University
1997-2000 Director of the Prime Program in Physiology, School of Medicine, Tulane University
1997-2000 Associate Course Director, Medical Physiology, School of Medicine, Tulane University.
1998-2000 Lecturer, Advanced Topics in Electrophysiology; Department of Physiology, School of Medicine, Tulane University
TEACHING EXPERIENCE AT GEORGIA REGENTS UNIVERSITY (FORMERLY THE MEDICAL COLLEGE OF GEORGIA):
2001-2002 Small Group Conference Leader, Medical Physiology, Department of Physiology, Medical College of Georgia. (4 hours contact time, 8 hours preparation time)
2001-2005 Small Group Conference Leader, Graduate Renal Physiology, Department of Physiology, Medical College of Georgia. (4 hours contact time, 8 hours preparation time)
2001-2002 Principles of Human Physiology (Allied Health Physiology; 10 hours of contact time teaching Renal Physiology, 80 hours preparation time)
2001-2003 Physiology Core Course, Essentials in Physiology and Pharmacology Body Fluids lectures, (4 hours contact time, 10 hours preparation time)
2002-2004 Medical Physiology Course (SOM 5150), Renal Physiology Micturition and Acid-Base Regulation Lectures (22 hours contact time, 88 hours preparation time)
2001-2007 Course Director, Scientific Communications, School of Graduate Studies, Medical College of Georgia
2002- 2003 Lecturer, Advanced Neural and Endocrine Systems (PHY-8320), School of Graduate Studies, Medical College of Georgia. (3 hours contact time, 9 hours preparation time)
2002-2010 Cardiovascular Physiology and Pharmacology (SGS 8120), School of Graduate Studies, Medical College of Georgia, Lecture on Renal Hemodynamics and GFR (3 hour contact time, 3 hours preparation time)
TEACHING EXPERIENCE AT GEORGIA REGENTS UNIVERSITY (FORMERLY THE MEDICAL COLLEGE OF GEORGIA): continued
2003-2004 Medical Physiology Course (SOM 5150), Body Fluids Lecture (2 hours contact time, 8 hours preparation time)
2003-2014 Lecturer, Scientific Communications, School of Graduate Studies (SGS 8012), Medical College of Georgia. (2 hour contact time, 4 hours preparation time)
2003-2014 Scientific Grant Writing, (SGS 8130) Grant Review Process and Mock Study Section, (5 hours contact time, 27 hours grant preparation)
2004 Lecturer, Vascular Changes in Exercise, School of Kinesiology, Augusta State University. (2.5 hours contact time, 8 hours preparation time)
2004-2014 Medical Physiology Course (SOM 5150), Renal Physiology, Micturition and Acid-Base Regulation Lectures (18 hours contact time, 72 hours preparation time)
2005-2014 Physiology Core Course, Integrated Systems Biology (SGS 8033) Homeostasis lecture, (1 hour contact time, 2 hour preparation time), Body Fluids Lecture (2 hour contact time, 2 hours preparation time)
2005-2014 Responsible Conduct of Research (SGS 8011), Research Misconduct, (1 hour contact time, 7 hours preparation time)
2005-2008 Small Group Conference Leader, Graduate Renal Physiology, Department of Physiology, Medical College of Georgia. (4 hours contact time, 5 hours preparation time)
2006 Critical Analysis of the Mechanisms of Disease (SGS 8065), End organ damage in hypertension. (1 hour contact time, 5 hours preparation time)
2006-2012 Advanced Study of Physiology-Renal Physiology (PHY 8340). Course Director: Mike Brands. Co-Director Ed Inscho and David Pollock. Fall, 2006 (21 hours contact time, 42 hours preparation time)
2007. Invited lecture in Physiology and Pathophysiology of the Kidney (Phys 930) in the Department of Cellular and Integrative Physiology at the University of Nebraska in Omaha, NE. Graduate Student lecture entitled “Renal vascular impairment in hypertension”.
2010-2014 Cardiovascular Physiology and Pharmacology (SGS 8120), School of Graduate Studies, Medical College of Georgia, Lecture on Renal regulation of circulatory volume (3 hours contact time, 3 hours preparation time)
2013-2014 Advanced Study of Physiology-Renal Physiology (PSIO 8360). Course Director: Edward W. Inscho. Co-Director David M. Pollock. Fall, 2013 (21 hours contact time, 42 hours preparation time)
2013-2014 Current Trends in Physiology (PSIO 8350). Course Director: David M. Pollock. Co-Director Edward W. Inscho. Fall, 2013 (21 hours contact time, 42 hours prep)
TEACHING EXPERIENCE AT THE UNIVERSITY OF ALABAMA AT BIRMINGHAM:
2015 Judge for the Department of Medicine 31st Annual Trainee Research Symposium
2015 Small Group Session Leader for the Body Fluids Block of the Medical Physiology Course (PCL1120)
2015 Small Group Session Leader for the Renal Block of the Medical Physiology Course (PCL1170)
2015 Session Leader from Translational Research Immersion Module (TRIM) for 1st year Internal Medicine Residents in the Department of Medicine, October 29, 2015
2015 SeCURE Program-Summer research undergraduate rotation in collaboration with the University of California at Merced. Howard Cha worked the DOCA-salt project with Dr. Guan, June 1, 2015 through August 1, 2015.
2016 Session Leader from Translational Research Immersion Module (TRIM) for 1st year Internal Medicine Residents in the Department of Medicine, January 7, 2016.
TEACHING EXPERIENCE AT THE UNIVERSITY OF ALABAMA AT BIRMINGHAM:
2016 Judge for the Department of Medicine 32nd Annual Trainee Research Symposium, March 2, 2016
2016 Faculty evaluator of senior presentations for the Psychology Capstone course (PY490) April 12, 2016.
2016 Small Group Session Leader for the Body Fluids Block of the Medical Physiology Course May 6&9 2016 (PCL1170)
2016 Small Group Session Leader for the Renal Block of the Medical Physiology Course May 10&11, 2016 (PCL1170)
2016 SeCURE Program-Summer research undergraduate rotation in collaboration with the University of California at Merced. Estevan Beltran worked with Justin Van Beusecum on a TLR4 project, June 1, 2016 through August 1, 2016.
2016 Lecturer in Advanced topics in Renal Physiology (GBS-747). Topic: Control of RBF and GFR. August 15, 2016, 2 hours/lecture
2016 SMART Grant review session for postdocs and fellows August 29, 2016 1-2 hours/ session. 1-2 hours per session
2016 Session Leader from Translational Research Immersion Module (TRIM) for 1st year Internal Medicine Residents in the Department of Medicine, September 29, 2016. 6 hours/date
2017 Session Leader from Translational Research Immersion Module (TRIM) for 1st year Internal Medicine Residents in the Department of Medicine, February 2, 2017. 6 hours/date
2017 Renal Lectures (3 lectures) for the Medical Physiology Course May 4, 2017 (PCL1170) 1 hour/lecture
2017 Small Group Session Leader for Body Fluid and Physiology Behind Clinical Cases for the Medical Physiology Course May 5, 8, 9 and 10, 2017 (PCL1170) 2 hours/day
2017 Renal Physiology Review session for the Medical Physiology Course May 10, 2017 (PCL1170) 1 hour/ session
2017 Kidney Undergraduate Research Experience (KURE) Program-Summer research undergraduate rotation in collaboration with the University of California at Merced and the University of Evansville. Josh Baty worked with Dr. Zhengrong Guan on a calcium signaling project in vascular smooth muscle. June 1 through July 28, 2017. Five hours/week
2017 Lecturer in the Fundamentals of Renal Physiology Course (GBS748VTC) September 11, 2017. Three hours/lecture.
2017 Session Leader from Translational Research Immersion Module (TRIM) for 1st year Internal Medicine Residents in the Department of Medicine, September 28, 2017. 6 hours/date
2018 Noon Clinical Conference for the UAB Nephrology Fellows on Renal Physiology: Regulation of Glomerular Hemodynamics January 11, 2018.
2018 Noon Clinical Conference for the UAB Nephrology Fellows on Renal Physiology: Regulation of Renal Blood Flow and Renal Hemodynamics January 18, 2018.
2018 Session Leader from Translational Research Immersion Module (TRIM) for 1st year Internal Medicine Residents in the Department of Medicine, March 1, 2018. 6 hours/date
2018 Renal Lectures (3 lectures) for the Medical Physiology Course (PCL1170) May 1 and 2, 2018 (PCL1170), 1 hour/lecture
2018 Small Group Session Leader for Body Fluid and Physiology Behind Clinical Cases for the Medical Physiology Course May 3, 4, 8 and 9, 2018 (PCL1170) 2 hours/day
2018 Renal Physiology Review session for the Medical Physiology Course May 10, 2018 (PCL1170) 1 hour/ session
TEACHING EXPERIENCE AT THE UNIVERSITY OF ALABAMA AT BIRMINGHAM continued:
2018 KURE Program-Summer research undergraduate rotation in collaboration with the University of California at Merced and the Brigham Young University. Brian Freeman (Univ. CA-Merced; Inscho) and Stephen Aldous (BYU; Guan and Inscho) on projects related to the impact of TLR4 activation and ischemia-reperfusion on afferent arteriole autoregulatory behavior. May 31 through August 3 2018. Eight contact hours/week.
2018 Session Leader from Translational Research Immersion Module (TRIM) for 1st year Internal Medicine Residents in the Department of Medicine, November 29, 2018. 6 hours/date
2018 Judge for the Medical Student Research Day presentations, August 7, 2018
2019 Renal Lectures (3 lectures) for the Medical Physiology Course (PCL1170) May 7 and 8, 2019 (PCL1170), 1 hour/lecture
2019 Small Group Session Leader for Body Fluid and Physiology Behind Clinical Cases for the Medical Physiology Course May 8, 9, 10, 13, 14 and 15, 2019 (PCL1170) 2 hours/day
2019 Renal Physiology Review session for the Medical Physiology Course May 16, 2019 (PCL1170) 1 hour/ session
2019 KURE Program-Summer research undergraduate rotation in collaboration with the Notre Dame University. Bailey McEachen on the impact of tempol treatment on ischemia-reperfusion injury and afferent arteriole autoregulatory behavior. June 3 through August 2 2019. Eight contact hours/week.
2019 Panelist for the “Specific Aims Workshop” as part of the Scientific Study Section Meeting And Research Training (SMART) program January 28, 2019.
2020 Virtual Renal Lectures (3 lectures) for the Medical Physiology Course (PCL1170) May 5 and 67 and 8, 2020 (PCL1170), 1 hour/lecture
2020 Virtual Small Group Session Leader for Body Fluid and Physiology Behind Clinical Cases for the Medical Physiology Course May 6, 7, 8, 11, 12 and 13, 2020 (PCL1170) 2 hours/day
2020 Renal Physiology Review session for the Medical Physiology Course May 14, 2020 (PCL1170) 1 hour/ session
2020 Lecturer on “The Kidney and Blood Pressure Regulation in the PROmoTE course entitled Critical Approaches and Clinical Evaluation of Kidney July 22, 2020 (PSDO 720) 1 hour/session.
2020 Cardio-Renal Physiology Journal Club (GBSC-700). 1 Credit Hour, Fall 2020, August 27 – December 3, weekly, Thursdays, 3:00-5:00pm KAUL 837/zoom
SERVICE ON DEPARTMENTAL AND UNIVERSITY COMMITTEES AT TULANE UNIVERSITY SCHOOL OF MEDICINE:
1994-1998 Committee on Graduate Studies in Physiology
1995-1996 Curriculum Review Committee for Community Medicine
1995-2000 Faculty Representative to the Phoenix Society
1995-2000 Admissions Interviewer of Medical School Applicants
1997 Curriculum Review Committee for the Junior Clerkship in Internal Medicine
1997-2000 Curriculum Committee for the School of Medicine
1997-1998 Dean's Distinguished Faculty Forum Committee
1998-1999 Chairman of the Curriculum Review Committee for the Pediatrics Clerkship
1998-2000 Chairman of the Physiology Department Seminar Series
1998-2000 Medical Education Committee
1999 Academic and Administrative Review Committee for the Department of Anatomy
1999 Member of the Pre-clinical Vision Group Chaired by Dr. Kevin Krane, Vice Dean for Academic Affairs
SERVICE ON DEPARTMENTAL AND UNIVERSITY COMMITTEES AT TULANE UNIVERSITY SCHOOL OF MEDICINE continued:
2000. Partners in TIME Incentive Mini-grants Review Committee
1999-2000 Committee on Medical Informatics in Medical Education
1999-2000 Personnel and Honors Committee, Tulane University School of Medicine
2000 Chairman of the Tulane Research Day Physiological and Pathophysiological Mechanisms Poster Discussion Group
2000 Personnel and Tenure Committee, Department of Physiology, Tulane University School of Medicine
SERVICE ON COMMITTEES AT GEORGIA REGENTS UNIVERSITY (FORMERLY THE MEDICAL COLLEGE OF GEORGIA):
2001 Deans Representative for the Second Exam of Billie Moore, Molecular Medicine
2001-2010 Vice Chairman of the Department of Physiology
2001-2010 Committee on Graduate Studies in Physiology
2001-2002 Member of the Vascular Biology Center Faculty Search Committee
2002. MCG Subcommittee on Animal Use for Research and Education
2002-2005 Chairman of a MCG Subcommittee on Animal Use for Research and Education
2001-2003 Department of Physiology Space Committee
2001 Organizer and Director of the Physiology Department Retreat
2001-2005 Member M.D./Ph. D. Advisory Committee
2001-2010 Physiology Chairman’s Advisory Committee
2001-2003 Director of the Physiology Endowed Lecture Series
2002. Promotion and Tenure Committee; Department of Cellular Biology and Anatomy
2001-2014 Judge, Georgia Health Sciences University Graduate Research Day
2001. Chairman of the Physiology Planning Committee for Salary Release Funds
2001 Dean’s Representative for Second Examination
2002 Chairman of the Physiology Faculty Review Committee
2002. Dean’s Representative for the Second Examination of Ahmed A. El-Marakby
2003-2011 Member of the MCG Campus Review Body
2005. Chairman of the Faculty Academic Tenure and Promotions Appeals Committee
2004 Subcommittee Member to Revise Faculty Academic Tenure and Promotions Criteria
2004-2006 Member of the Faculty Appointment, Development Promotions and Tenure Committee for the School of Medicine
2004-2005 Chairman of the Task Force for Distinguished Faculty for the School of Medicine
2005-2010 Director of the MD/PhD Program
2005-2014 Member Recruitment & Admission Committee for the School of Graduate Studies
2005 Chairman of an ad hoc Academic Review Committee
2005-2010 Member of the MCG Committee on Committees
2006-2007 Member of the Liaison Committee on Medical Education (LCME) School of Medicine Self Study Task force
2006-2009 Member of the Deans Planning and Advisory Committee for the School of Medicine, Medical College of Georgia
2006 Deans Representative for the Second Exam of Alexis Simpkins, Vascular Biology Center
2006-2014 Division of Sponsored Research Advisory Committee
2006-2010 Member of the Vascular Biology Center Hypertension Planning Committee
2007-2014 Member of the STAR Recruitment and Admission Committee for the School of Graduate Studies
2008-2010 Chairman of the MCG Intramural Program Review
SERVICE ON COMMITTEES AT GEORGIA REGENTS UNIVERSITY continued):
2008-2009 Member of the Search Committee of the Chair of the Department of Basic Sciences at the University of Georgia for the Medical College of Georgia partnership campus.
2009 Deans Representative for the Second Exam of Rusty Johnson, Molecular Medicine
2009-2013 Member of the Internal Advisory Committee of the Diabetes and Obesity Discovery Institute
2010-2013 Member of the Medical College of Georgia Post-Tenure Review Committee.
2010-2014 Member of the University Budget and Planning Committee
2011-2014 Member of the Long Term Strategic Planning Committee
2011-2014 Member of the Diversity Task Force
2011-2014 Member of the Affiliations Partnership Committee
2011-2014 Member of the Committee on Philanthropy
2011-2012 Member of the Business, Planning and Development Committee
2011-2014 Member of the Faculty Evaluation Committee
2011-2014 Member of the Senior Leadership Committee
2011-2014 Member of the MD/PhD Advisory Committee
2011-2014 Member of the Quality and Safety Steering Committee
2012-2013 Co-Chair of the Taskforce Reviewing Basic Neuroscience Department
2012-2013 Search Committee Member for the Senior Vice President for Administration and Finance: Search terminated April 1, 2013
2012 Search Committee Member for the Warren Endowed Chair for Obesity and Diabetes
2012-2014 Faculty Mentor for Dr. Patricia Schoenlein in the Department of Cell Biology and Anatomy at Georgia Regents University
2012-2013 Member of the GHSU/MCG Post-tenure Review Committee (3 year term)
2012-2014 Chairman of the Academic Standards Committee, Georgia Regents University, College of Graduate Studies
2013-2014 Member of the GRU/MCG FDPT Pre-tenure Review Committee (3 year term)
2013 Oral Biology P&T committee.
2013-2014 Faculty Mentor for Dr. Jian-Kang Chen in the Department of Cell Biology and Anatomy at Georgia Regents University
SERVICE ON COMMITTEES AT THE UNIVERSITY OF ALABAMA AT BIRMINGHAM:
2015 - present UAB School of Medicine Research Faculty Onboarding Group.
2015 - present Judge for the DOM Trainee Research Symposium
2015 - present Member of the Pilot Development Team for Dr. Timothy C. Lee in collaboration with the UAB Center for Clinical & Translational Science (CCTS).
2015 - present Judging for the Annual Vascular Biology & Hypertension Symposium
2015 - present Judging for the Graduate Program in Biomedical Sciences poster sessions
2017 - present Member of the Kaul Structural Issues Task force assembled by Etty (Tika) Benveniste, Ph.D., Senior Associate Dean for Research Administration, SOM, Associate Vice President for Medicine and Basic Sciences
2017 - present Member of the Division of Nephrology Promotion and Tenure Committee
2018 - present Member of the Internal Advisory Committee for the PRIME T32 Training Grant
2020 Judge for the 2020 Graduate Biomedical Sciences/Joint Health Sciences Research Symposium, August 14, 2020 4.5 hours.
SERVICE ON DISSERTATION COMMITTEES: Committee Member
Owen Wilson Department of Physiology withdrew in 1994
Annette Von Thun Department of Physiology M.D. /Ph.D. awarded in 1995
Victor Ruiz-Velasco Department of Physiology Ph.D. awarded in 1996
Etoi Garrison Department of Pharmacology Ph.D. awarded in 1997
Wenliang Shi Department of Physiology Ph.D. awarded in 1998
Stephanie Talton Department of Physiology Withdrew from the program to attend Medical School
Chi-Tarng Wang Department of Physiology Ph.D. awarded in 1999
Sophia Omoro Department of Physiology Ph.D. awarded in 2000
David Lambert Department of Pharmacology Master’s Degree awarded in 1999
Hunter Champion Department of Pharmacology Ph.D. awarded in 1999
Jun Dai Department of Structural PhD awarded in 2000
and Cellular Biology Ph.D. awarded in 2000, Post doc with Dr. Victor Hsu at Harvard University Medical School
Brett Mitchell Department of Physiology PhD awarded in 2003
Jennifer Sasser Vascular Biology Center Ph.D. awarded in 2005
Christine Rigsby Department of Physiology Ph.D. awarded in 2007
Tracy Bell Department of Physiology Ph.D. awarded in 2007
Jeniel Parmar Department of Physiology Ph.D. awarded in 2012
Jan Foster Vascular Biology Center Ph.D. awarded in 2009
Trevor Hardigan Department of Physiology Expected Ph.D. in 2016; M.D. in 2018
John Miller Allan Department of Medicine Master’s Degree Defense July 2018
Dingguo Zhang Department of Medicine Ph.D. Expected in July 2020
Committee Chairman:
David Osmond Department of Physiology Ph.D. awarded in 2011
Matt Socha Vascular Biology Center Ph.D. awarded in 2009
Justin Van Beusecum Department of Medicine Ph.D. awarded June 2017
STUDENT/TRAINEE MENTORING:
2015 Niranjana Natarajan, Graduate Student with Jennifer Pluznick in the Dept of Physiology, Johns Hopkins University School of Medicine
2015-present Kênia Pedrosa Nunes, Ph.D. Assistant Professor, Dept. of Biological Sciences, Florida Institute of Technology.
2016-present Maria Alicia Carrillo-Sepulveda, BSN, Ph.D., Assistant Professor, Dept. of Biomedical Sciences, New York Institute of Technology College of Osteopathic Medicine.
2016-present Vinicia Biancardia. Asst. Professor, Auburn University Dept. of Anatomy, Physiology & Pharmacology College of Veterinary Medicine
2017-present Jessica Faulkner, Augusta University Postdoctoral Fellow with Eric Belin de Chantemele
2017-present Eman Gohar, Postdoctoral Fellow in the Dept. of Medicine at the Univ. of Alabama at Birmingham with David Pollock
2017-present Josh Baty, Undergraduate student at the University of Evansville, Evansville, Indiana.
2018-present Brian Freeman, Undergraduate student at the University of California Merced.
2019-present Bailey McEachen, Undergraduate student at the Notre Dame University.
COMMUNITY SERVICE:
1994-1999 Board of Directors for the Destrehan Booster Club, Destrehan, LA.
1995-1999 Vice-President of the Destrehan Booster Club, Destrehan, LA.
1996 Microscope Committee for the Schoeffner Elementary School, Destrehan, LA.
1996 Assistant Baseball Coach for Destrehan Booster Club, Destrehan, LA.
1997-2000 District 3 Representative to the Citizens Advisory Panel to Industry, Destrehan, LA.
1997-2000 Member of the St. Charles United Methodist Church Choir, Destrehan, LA.
1998-2000 Member of the Administrative Board of the St. Charles United Methodist Church, Destrehan, LA.
2000 Faculty Mentor for "Careers in Science" Program for Destrehan High School, Destrehan, LA.
2000 Assistant Baseball Coach for Destrehan Booster Club, Destrehan. LA.
2006-2014 Member of the St. Marks United Methodist Church Choir, Augusta, GA.
2006-2014 River of Life Community Outreach, Augusta, GA.
2008-2013 Member of the St. Mark United Methodist Church Finance Committee, Augusta, GA.
2008-2010 Member of the St. Mark United Methodist Church Organ Committee, Augusta, GA.
2009-2014 Member of the St. Marks United Methodist Church Handbell Choir, Augusta, GA.
2010-2012 Chairman, St. Marks United Methodist Church Stewardship Campaign, Augusta, GA.
2013-2014 Member of the St. Marks United Methodist Church Staff Parish Relations Committee, Augusta, GA
2017-present Member of the Vestavia Hills United Methodist Church Choir, Vestavia Hills AL.
PUBLICATIONS:
1. Clark, Leland C., Eleanor W. Clark, Robert E. Moore, Douglas G. Kinnett and Edward W. Inscho. Room temperature-stable biocompatible fluorocarbon emulsions. Progress in Clinical Biological Research 122: 169-180, 1983.
2. Banks, Robert W., Edward W. Inscho and Eugene D. Jacobson. Histamine H2 receptor antagonists inhibit autoregulation of renal blood flow in the dog. Circulation Research, 64: 527-535, 1984.
3. Inscho, Edward W., William W. Wilfinger and Robert O. Banks. Dissociation and enrichment of rat atrial myocytes containing atrial natriuretic factor (ANF). Hormone Research, 24: 26-37, 1986.
4. Inscho, Edward W., William W. Wilfinger and Robert O. Banks. Age-related differences in the natriuretic and hypotensive properties of rat atrial extracts. Endocrinology, 121: 1662-1670, 1987.
5. Veldkamp, Peter J., Pamela K. Carmines, Edward W. Inscho and L. Gabriel Navar. Direct evaluation of the microvascular actions of atrial natriuretic peptide in juxtamedullary nephrons. American Journal of Physiology 254 (Renal Fluid and Electrolyte Physiology 23): F440-F444, 1988.
6. Wilfinger, William W., Edward W. Inscho and Robert O. Banks. The biological and immunological properties of fractionated atrial extracts from young and old rats. Life Sciences. 45: 2333-2342, 1989.
7. Carmines, Pamela K., Edward W. Inscho and Robert C. Gensure. Arterial pressure effects on preglomerular microvasculature of juxtamedullary nephrons. American Journal of Physiology 258 (Renal Fluid and Electrolyte Physiology 27): F94-F102, 1990.
8. Inscho, Edward W., Pamela K. Carmines, Anthony K. Cook and L. Gabriel Navar. Afferent arteriolar responsiveness to altered perfusion pressure in renal hypertension. Hypertension 15: 748-752, 1990.
9. Inscho, Edward W., Pamela K. Carmines and L. Gabriel Navar. Prostaglandin influences on afferent arteriolar responses to angiotensin II. American Journal of Physiology 259 (Renal Fluid and Electrolyte Physiology 28): F157-F163, 1990.
10. Carmines, Pamela K., Edward W. Inscho, Joseph M. Ortenberg and Anthony K. Cook. Determinants of renal microvascular autoregulatory behavior in normal and hypertensive states. Kidney International 39 (Supplement 32): S89-S93, 1991.
11. Navar, L. Gabriel, Edward W. Inscho and Mariano Ibarrola. Communication between the macula densa and the afferent arteriole. Kidney International 39 (Supplement 32): S78-S82, 1991.
12. Inscho, Edward W., Pamela K. Carmines and L. Gabriel Navar. Juxtamedullary afferent arteriolar responses to P1 and P2 purinergic stimulation. Hypertension 17: 1033-1037, 1991.
13. Ibarrola, A. Mariano, Edward W. Inscho, Richard C. Vari and L. Gabriel Navar. Influence of adenosine receptor blockade on renal function and renal autoregulation. Journal of the American Society of Nephrology 2: 991-999, 1991.
14. Carmines, Pamela K. and Edward W. Inscho. Perfusate composition modulates in vitro renal microvascular pressure responsiveness in a segment-specific manner. Microvascular Research 43: 347-351, 1992.
15. Ortenberg, Joseph M., Anthony K. Cook, Edward W. Inscho and Pamela K. Carmines. Attenuated afferent arteriolar response to acetylcholine in Goldblatt hypertension. Hypertension 19: 785-789, 1992.
16. Inscho, Edward W., Kazuhisa Ohishi and L. Gabriel Navar. Effects of ATP on the pre- and postglomerular juxtamedullary microvasculature. American Journal of Physiology 263 (Renal Fluid and Electrolyte Physiology 32): F886-F893, 1992.
17. Ohishi, Kazuhisa, Pamela K. Carmines, Edward W. Inscho and L. Gabriel Navar. EDRF-angiotensin II interactions in afferent and efferent arterioles. American Journal of Physiology 263 (Renal Fluid and Electrolyte Physiology 32): F900-F906, 1992.
18. Carmines, Pamela K. and Edward W. Inscho. Renal arteriolar angiotensin responses during varied adenosine receptor activation. Hypertension 23 (Supplement 1): I-114-I-119, 1994.
19. Ruiz-Velasco, Victor, M. Beatriz Mayer, Edward W. Inscho and Lin J. Hymel. Modulation of dihydropyridine receptors in vascular smooth muscle cells by membrane potential and cell proliferation. European Journal of Pharmacology 268: 311-318, 1994.
20. Takenaka, Tsuneo, Lisa M. Harrison-Bernard, Edward W. Inscho, Pamela K. Carmines and L. Gabriel Navar. Autoregulation of afferent arteriolar blood flow in juxtamedullary nephrons. American Journal of Physiology 267 (Renal Fluid and Electrolyte Physiology 35): F879-F887, 1994.
21. Inscho, Edward W., Kazuhisa Ohishi, Anthony K. Cook, Todd P. Belott, and L. Gabriel Navar. Calcium activation mechanisms in the renal microvascular response to extracellular ATP. American Journal of Physiology 268 (Renal Fluid and Electrolyte Physiology 37): F876-F884, 1995.
22. Inscho, Edward W., Todd P. Belott, Michael J. Mason, Jeffry B. Smith and L. Gabriel Navar. Extracellular ATP increases cytosolic calcium in cultured renal arterial smooth muscle cells. Clinical and Experimental Pharmacology and Physiology 23: 503-507, 1996.
23. Inscho, Edward W., Anthony K. Cook and L. Gabriel Navar. Pressure-mediated vasoconstriction of juxtamedullary afferent arterioles involves P2-purinoceptor activation. American Journal of Physiology 271 (Renal Fluid and Electrolyte Physiology 40): F1077-F1085, 1996.
24. Inscho, Edward W., John D. Imig and Anthony K. Cook. Afferent and efferent arteriolar vasoconstriction to angiotensin II and norepinephrine involves release of Ca2+ from intracellular stores. Hypertension 29: 222-227, 1997.
25. Ichihara, Atsuhiro, Edward W. Inscho, John D. Imig, Robert E. Michel and L. Gabriel Navar. Role of renal nerves in afferent arteriolar reactivity in angiotensin-induced hypertension. Hypertension 29: 442-449, 1997.
26. Inscho, Edward W., Michael J. Mason, Alan C. Schroeder, Paul C. Deichmann, Karl D. Steigler and John D. Imig. Agonist-induced calcium regulation in freshly isolated renal microvascular smooth muscle cells. Journal of the American Society of Nephrology 8: 569-579, 1997.
27. Inscho, Edward, W. Anthony K. Cook, Vy Mui and John D. Imig. Calcium mobilization contributes to pressure-mediated afferent arteriolar vasoconstriction. Hypertension 31: 421-428, 1998.
28. Ichihara, Atsuhiro, Edward W. Inscho, John D. Imig and L. Gabriel Navar. Neuronal nitric oxide synthase modulates rat renal microvascular function. American Journal of Physiology 274 (Renal Physiology 43): F516-F524, 1998.
29. Inscho, Edward W., Anthony K. Cook, Vy Mui and Jason Miller. Direct assessment of renal microvascular responses to P2 purinoceptor agonists. American Journal of Physiology 274 (Renal Physiology 43): F718-F727, 1998.
30. Ichihara, Atsuhiro, John D. Imig, Edward W. Inscho and L. Gabriel Navar. Interactive nitric oxide-angiotensin II influences on renal microcirculation in angiotensin II-induced hypertension. Hypertension 31: 1255-1260, 1998.
31. Ichihara, Atsuhiro, John D. Imig, Edward W. Inscho and L. Gabriel Navar. Cyclooxygenase-2 participates in tubular flow-dependent afferent arteriolar tone: Interaction with neuronal nitric oxide synthase in rat kidneys. American Journal of Physiology 275 (Renal Physiology 44): F605-F612, 1998.
32. Inscho, Edward W., John D. Imig, Paul C. Deichmann and Anthony K. Cook. Candesartan-cilexetil protects against loss of autoregulatory efficiency in angiotensin II infused rats. Journal of the American Society of Nephrology 10 (Supplement 11): S178-S183, 1999.
33. Inscho, Edward W., Elizabeth A. LeBlanc, Bao Thang Pham, Steven White and John D. Imig. Purinoceptor-mediated calcium signaling in preglomerular smooth muscle cells. Hypertension 33: 195-200, 1999.
34. Imig, John D., Edward W. Inscho, Paul C. Deichmann, K. Malla Reddy and John R. Falck. Afferent arteriolar vasodilation to 11, 12-epoxyeicosatrienoic acid involves protein kinase A. Hypertension 33: 408-413, 1999.
35. Majid, Dewan S. A., Edward W. Inscho and L. Gabriel Navar. P2-purinoceptor saturation by ATP impairs renal autoregulation in dogs. Journal of the American Society of Nephrology 10: 492-498, 1999.
36. Inscho, Edward W., Alan C. Schroeder, Paul C. Deichmann and John D. Imig. ATP-mediated calcium signaling in preglomerular smooth muscle cells. American Journal of Physiology 276 (Renal Physiology 45): F450-F456, 1999.
37. Imig, John D., John R. Falck and Edward W. Inscho. Contribution of cytochrome P450 epoxygenase and hydroxylase pathways to afferent arteriolar autoregulatory responsiveness. British Journal of Pharmacology 127: 1399-1405, 1999. PMCID: PMC1760652
38. Marriott, I., Edward W. Inscho, and Kenneth L. Bost. Extracellular uridine nucleotides initiate cytokine production by murine dendritic cells. Cellular Immunology 195: 147-156, 1999.
39. Schroeder, Alan C., John D. Imig, Elizabeth A. LeBlanc, Bao Thang Pham, David M. Pollock and Edward W. Inscho. Endothelin-mediated calcium signaling in preglomerular smooth muscle cells. Hypertension 35: 280-286, 2000.
40. Imig, John D., Bao Thang Pham, Elizabeth A. LeBlanc, K.M. Reddy, John R. Falck and Edward W. Inscho. Cytochrome P450 and cyclooxygenase metabolites contribute to the endothelin-1 afferent arteriolar vasoconstrictor and calcium responses. Hypertension 35: 307-312, 2000.
41. Imig, John D., Anthony K. Cook and Edward W. Inscho. Postglomerular vasoconstriction to angiotensin II and norepinephrine depends on intracellular calcium release. General Pharmacology 34: 409-415, 2000; appeared in 2001.
42. Nishiyama, Akira, Edward W. Inscho, and L. Gabriel Navar. Interactions of adenosine A1 and A2a receptors on renal microvascular reactivity. American Journal of Physiology 280 (Renal Physiology 49): F406-F414, 2001.
43. White, Steven M., John D. Imig and Edward W. Inscho. Calcium signaling pathways utilized by P2X receptors in freshly isolated preglomerular vascular smooth muscle cells. American Journal of Physiology: Renal Physiology 280: F1054-F1061, 2001
44. Zhao, Xueying, Edward W. Inscho, Muralidhar Bondlela, John R. Falck and John D. Imig. The CYP450 hydroxylase pathway contributes to P2X receptor-mediated afferent arteriolar vasoconstriction. American Journal of Physiology: Heart and Circulatory Physiology 281: H2089-H2096, 2001.
45. Inscho, Edward W. and Anthony K. Cook. P2 receptor-mediated afferent arteriolar vasoconstriction during calcium channel blockade. American Journal of Physiology: Renal Physiology 282: F245-F255, 2002.
46. Dai, Jun., Edward W. Inscho and Steven M. Hill. Modulation of intracellular calcium and calmodulin by melatonin in MCF-7 human breast cancer cells. Journal of Pineal Research 32: 112-119, 2002.
47. Bivalacqua, Trinity J., Hunter C. Champion, Mrugeshkumar K. Shah, Darcy M. Baird, Edward W. Inscho and Phillip J. Kadowitz. Comparative responses to α, β-methylene ATP in the pulmonary, mesenteric and hindlimb vascular bed of the cat. Journal of Applied Physiology 93: 1287-1295, 2002.
48. Zhao, Xueying, David M. Pollock, Edward W. Inscho, Darryl C. Zeldin and John D. Imig. Decreased renal CYP2C enzymes and impaired endothelium-dependent dilation are associated with angiotensin-II salt sensitive hypertension. Hypertension 41: 709-714, 2003.
49. Inscho, Edward W., Anthony K. Cook, John D. Imig, Catherine Vial and Richard J. Evans. Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior. Journal of Clinical Investigation 112: 1895-1905, 2003. PMCID: PMC296993
50. Yiu, Shih Shen, Xueying Zhao, Edward W. Inscho and John D. Imig. 12-Hydroxyeicosatetraenoic acid participates in angiotensin II afferent arteriolar vasoconstriction by activating L-type calcium channels. Journal of Lipid Research 44: 2391-2399, 2003.
51. Inscho, Edward W., Anthony K. Cook, Jim Murzynowski and John D. Imig. Elevated arterial pressure impairs autoregulation independently of AT1 receptor activation. Journal of Hypertension 22: 811-818, 2004.
52. Sullivan, Jennifer C., Elizabeth D. Loomis, Matthew Collins, John D. Imig, Edward W. Inscho and Jennifer S. Pollock. Age-related alterations in NOS and oxidative stress in mesenteric arteries from male and female rats. Journal of Applied Physiology 97: 1268-1274, 2004.
53. Zhao, Xueying, Edward W. Inscho and John D. Imig. P2X receptor stimulated calcium responses in preglomerular vascular smooth muscle cells involves 20-HETE. Journal of Pharmacology and Experimental Therapeutics 311(3): 1211-1217, 2004.
54. Pollock, David M., John M. Jenkins, Anthony K. Cook, John D. Imig and Edward W. Inscho. L-type calcium channels in the renal microcirculatory response to endothelin. American Journal of Physiology: Renal Physiology 288: F771-F777, 2005.
55. Sharma, Kumar, Anthony K. Cook, Matt Smith and Edward W. Inscho. TGF-beta impairs renal autoregulation via ROS generation. American Journal of Physiology Renal Physiology 288: F1069-F1077, 2005.
56. Fuller, Andrew J., Benjamin C. Hauschild, Romer Gonzalez-Villalobos, Mouhamed S. Awayda, John D. Imig, Edward W. Inscho and L. Gabriel Navar. Calcium and chloride channel activation by angiotensin II-AT1 receptors in preglomerular vascular smooth muscle cells. American Journal of Physiology: Renal Physiology: 289: F760-F767, 2005. PMCID: PMC1314975
57. Zhao, Xueying, Anthony K. Cook, Mary Field, Brentan Edwards, Shali Zhang, Zhanying Zhang, Jennifer S. Pollock, John D. Imig and Edward W. Inscho. Impaired Ca2+ signaling attenuates P2X receptor-mediated vasoconstriction of afferent arterioles in angiotensin II hypertension. Hypertension, 46: 562-568, 2005.
58. Inscho, Edward W., John D. Imig, Anthony K. Cook and David M. Pollock. ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin. British Journal of Pharmacology, 146: 1019-1026, 2005. PMCID: PMC1751231
59. Schneider, Markus P., Edward W. Inscho and David M. Pollock. Attenuated vasoconstrictor responses to endothelin in afferent arterioles during a high salt diet. American Journal of Physiology: Renal Physiology, 292:F1208-14, 2007.
60. Rivera, Ian, Shali Zhang, Barry Fuller, Brentan Edwards, Mario B. Marrero and Edward W. Inscho. P2 receptor regulation of [Ca2+]i in cultured mouse mesangial cells. American Journal of Physiology-Renal Physiology: 292: F1380-F1389, 2007.
61. Tostes, Rita C., Fernanda R.C. Giachini1, Fernando S. Carneiro, Romulo Leite, Edward W. Inscho and R. Clinton Webb. Determination of adenosine effects and adenosine receptors in murine corpus cavernosum. Journal of Pharmacology and Experimental Therapeutics 322: 768-685, 2007.
62. Elmarakby, Ahmed A., Jeffrey J. Olearczyk, Aarthi Sridhar, Jeffrey E. Quigley, Anthony Cook, Edward Inscho, David M. Pollock, and John D. Imig. Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension. Hypertension 50 (6): 1069 - 1076, 2007. PMCID: PMC2491337
63. Carneiro, Fernando S. Fernanda R. C. Giachini, Victor V. Lima, Zidonia N. Carneiro, Romulo Leite, Edward W. Inscho, Rita C Tostes, R. Clinton Webb. Adenosine actions are preserved in corpus cavernosum from obese and type II diabetic db/db mouse. Journal of Sexual Medicine, 5(5) 1156-1166, 2008. PMCID:PMC3016713
64. Luo, Pengcheng, Yiqiang Zhou, Hsin-Hsin Chang, Jie Zhang Tsugio Seki, Cong-Yi Wang, Edward W. Inscho, Mong-Heng Wang. Glomerular 20-HETE, EETs and TGF-β1 in diabetic nephropathy. American Journal of Physiology: Renal Physiology 296: F556-563, 2009. PMCID:PMC2660192
65. Inscho, Edward W., Anthony K. Cook, Li-Ming Jin and R. Clinton Webb. Rho-kinase inhibition reduces pressure-mediated autoregulatory adjustments in afferent arteriolar diameter. American Journal of Physiology: Renal Physiology 296: F590-597, 2009. PMCID:PMC2660197
66. Guan, Zhengrong, Jennifer S. Pollock, Anthony K. Cook, Janet Hobbs and Edward W. Inscho. Effect of epithelial sodium channel (ENaC) blockade on the myogenic response of rat juxtamedullary afferent arterioles. Hypertension, 54(5):1062-9, 2009. PMCID: PMC2766010
67. Giachini, Fernanda. R.C., David A. Osmond, Shali Zhang, Fernando S. Carneiro, Victor V. Lima, Edward W. Inscho, R. Clinton Webb and Rita C. Tostes. Clopidogrel, independent of the vascular P2Y12 receptor, improves arterial function in small mesenteric arteries from Ang II-hypertensive rats. Clinical Science 118: 463–471, 2010. PMCID: PMC3061981
68. Guan, Zhengrong, Barry S. Fuller, Tatsuo Yamamoto, Anthony K. Cook, Edward W. Inscho. Pentosan polysulfate treatment preserves renal autoregulation in Ang II-infused hypertensive rats via normalization of P2X1 receptor activation. American Journal of Physiology: Renal Physiology 298: F1276-F1284, 2010. PMCID: PMC2867410
69. Osmond, David A. and Edward W. Inscho P2X1 receptor blockade inhibits whole kidney autoregulatory behavior in vivo. American Journal of Physiology: Renal Physiology: F1360-F1368, 2010. PMCID: PMC2886815
70. Luo, Pengcheng, Hsin-Hsin Chang, Yiqiang Zhou, Shali Zhang, Sung Hee Hwang, Christophe Morisseau, Edward W. Inscho, Bruce D. Hammock, and Mong-Heng Wang. Inhibition and deletion of soluble epoxide hydrolase alleviates hyperglycemia in diabetic mice by promoting insulin secretion. Journal of Pharmacological and Experimental Therapeutics 334(2) 430-438, 2010. PMCID: PMC2913776
71. Toque, Haroldo A., Maritza J. Romero, Rita C. Tostes, Alia Shatanawi, Surabhi Chandra, Zidonia Carneiro, Edward Inscho, R. Clinton Webb, Ruth B. Caldwell, R. William Caldwell. p38 mitogen-activated protein kinase (MAPK) increases arginase activity and contributes to endothelial dysfunction in corpora cavernosa from angiotensin-II treated mice. Journal of Sexual Medicine, 12: 3857-3867, 2010. PMCID: PMC2996466
72. Brands, Michael W., Amy K.L. Banes-Berceli, Edward W. Inscho, Hind Al-Azawi, Ashlyn J. Allen, and Hicham Labazi. Interleukin-6 knockout prevents angiotensin II hypertension: Role of renal vasoconstriction and JAK2/STAT3 activation. Hypertension 56: 879-884, 2010. PMCID:PMC3500610
73. Inscho, Edward W., Anthony K. Cook, Andrea Clarke, Shali Zhang and Zhengrong Guan. P2X1 receptor-mediated vasoconstriction of afferent arterioles in Ang II-infused hypertensive rats fed a high salt diet. Hypertension 57: 780-787, 2011. PMCID: PMC3060280
74. Guan, Zhengrong, Matthew I. Giddens, David. A. Osmond, Anthony K. Cook, Janet L. Hobbs, Shali Zhang, Tatsuo Yamamoto, Jennifer S. Pollock, David M Pollock, Edward W. Inscho. Immunosuppression preserves renal autoregulatory function and microvascular P2X1 receptor reactivity in Ang II hypertensive rats. American Journal of Physiology: Renal Physiology, 304: F801-F807, 2013. PMCID: PMC3602698
75. Guan, Zhengrong, Sean T. Singletary, Anthony K. Cook, Jennifer S. Pollock and Edward W. Inscho. Sphingosine-1-phosphate evokes unique segment specific vasoconstriction of the renal microvasculature. Journal of the American Society of Nephrology 25 (8): 1774-1785, 2014. PMCID: PMC4116055.
76. Osmond, David A., Shali Zhang, Jennifer S. Pollock, Tatsuo Yamamoto, Carmen De Miguel and Edward W. Inscho. Clopidogrel preserves whole kidney autoregulatory behavior in Ang II-induced hypertension. American Journal of Physiology: Renal Physiology: 306: F319-F328, 2014. PMCID: PMC3949043.
77. Giachini, Fernanda R., Romulo Leite, David A. Osmond, Victor V. Lima, Edward W. Inscho, R. Clinton Webb and Rita C. Tostes. Anti-platelet therapy with clopidogrel prevents endothelial dysfunction and vascular remodeling in aortas from hypertensive rats. Plos One, DOI: 10.1371/journal.pone.0091890, 2014. PMCID: PMC3956760
78. Fellner, Robert C., Anthony K. Cook, Paul M. O'Connor, Shali Zhang, David M. Pollock and Edward W. Inscho. High salt diet blunts renal autoregulation by a reactive oxygen species-dependent mechanism. American Journal of Physiology: Renal Physiology: 307: F33-F40, 2014. PMCID: PMC4080153. Selected for APSselect for distinction in scholarship in the American Journal of Physiology - Renal Physiology. Also selected for an Editorial Focus commentary.
79. Pandit, Meghana M., Edward W. Inscho, Shali Zhang, Tsugio Seki, Rajeev Rohatgi, Luca Gusella, Bellamkonda Kishore and Donald E. Kohan. Flow regulation of endothelin-1 production in the inner medullary collecting duct. American Journal of Physiology: Renal Physiology 308: F541-F552, 2015. PMCID: PMC4360032.
80. Fellner, Robert C., Zhengrong Guan, Anthony K. Cook, David M. Pollock and Edward W. Inscho. Endothelin contributes to blunted renal autoregulation observed with a high salt diet. American Journal of Physiology: Renal Physiology: 309(8): F687-F696, 2015. PMCID: PMC4609914
81. Li, Xingsheng, John Knight, Sonia Fargue, Brianna Buchalski, Zhengrong Guan, Edward W Inscho, Abigail Liebow, Kevin Fitzgerald, William Querbes, W. Todd Lowther, Ross P. Holmes. Metabolism of 13C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by siRNA therapy targeting liver glycolate oxidase and hydroxyproline dehydrogenase. Bichemica et Biophysica Acta - Molecular Basis of Disease 1862: 233-239, 2016. PMCID: PMC4706777.
82. Guan, Zhengrong, Sean Singletary, Haword Cha, Justin P Van Beusecum, Anthony K. Cook, Jennifer S. Pollock, David M. Pollock, and Edward W. Inscho. Pentosan polysulfate preserves renal microvascular P2X1 receptor reactivity and autoregulatory behavior in DOCA-salt hypertensive rats. American Journal of Physiology: Renal Physiology 310(6): F456-F465, 2016. PMCID: PMC4796270
83. Van Beusecum, Justin P., Shali Zhang, Anthony K. Cook and Edward W. Inscho. Acute toll-like receptor 4 activation impairs rat renal microvascular autoregulatory behavior. Acta Physiologica 221 (3) 204-220, 2017. PMCID: PMC5641241
84. Guan, Zhengrong and Edward W. Inscho. Mechanisms of Sphingosine-1-phosphate-mediated Vasoconstriction of Rat Afferent Arterioles. Acta Physiologica, In Press. 2018 Feb; 222(2). doi: 10.1111/apha.12913. Epub 2017 Jul 13. Accepted June 16, 2017. Selected as a high scoring manuscript resulting in an Editorial Commentary. PMCID: PMC5741527
85. Gohar, Eman, Anthony K. Cook, David M. Pollock and Edward W. Inscho. Afferent arteriole responsiveness to endothelin receptor activation: Does sex matter? Biology of Sex Differences 10(1): 1 2019. (). PMCID: PMC6318859.
86. Van Beusecum, Justin P., Shali Zhang, Estevan Beltran, Anthony K. Cook, Richard P. Tobin, M. Karen Newell-Rogers, and Edward W. Inscho. Antagonism of MHC class II invariant chain peptide (CLIP) during chronic lipopolysaccharide treatment rescues afferent arteriole autoregulatory behavior. American Journal of Physiology-Renal Physiology August 16, 2019 317(4): F957-F966, 2019. PMCID: PMC6843034.
87. Guan, Zhengrong, Joshua J. Baty, Shali Zhang and Edward W. Inscho. Rho-Kinase Inhibitors Reduce Voltage-dependent Calcium Channel Signaling in Aortic and Renal Microvascular Smooth Muscle Cells. American Journal of Physiology-Renal Physiology 317(5): F1132-F1141, 2019. PMCID: PMC6879933.
88. Feng, Wenguang, Zhengrong Guan, Dongqi Xing, Xingsheng Li, Wei-Zhong Ying, Colton E. Remedies, Edward W. Inscho, and Paul W. Sanders. Avian Erythroblastosis Virus E26 Oncogene Homolog-1 (ETS-1) plays a role in renal microvascular pathophysiology in the Dahl salt-sensitive rat. Kidney International, 97: 528-537, 2020. PMCID: Pending: Available April 1, 20201.
89.
INVITED CHAPTERS/REVIEWS/ARTICLES/ LETTERS
1. Inscho, Edward W., Kenneth D. Mitchell and L. Gabriel Navar. Extracellular ATP in the regulation of renal microvascular function. FASEB Journal 8: 319-328, 1994.
90. Navar, L. Gabriel, Edward W. Inscho, Lisa M. Harrison-Bernard and Tsuneo Takenaka. Paracrine interactions regulating renal microcirculatory function. Clinical Investigation 72: 682-684, 1994.
91. Navar, L. Gabriel, Edward W. Inscho, Dewan S. A. Majid, John D. Imig, Lisa M. Harrison-Bernard and Kenneth D. Mitchell. Paracrine regulation of the renal microcirculation. Physiological Reviews 76: 425-536, 1996.
92. Inscho, Edward W. Purinoceptor-mediated regulation of the renal microvasculature. Journal of Autonomic Pharmacology 16: 385-388, 1996.
93. Navar, L. Gabriel, Edward W. Inscho, John D. Imig and Kenneth D. Mitchell. Heterogeneous activation mechanisms in the renal microvasculature. Kidney International 54 (Supplement 67): S-17-S-21, 1998.
94. Inscho, Edward W. Inaugural Meeting of the Gulf Coast Physiological Society. The Physiologist 43: 81-82, 2000
95. Inscho, Edward W. Modulation of Renal microvascular responsiveness by nitric oxide, In: Nitric Oxide and Regional Blood Flow. Edited by Phillip J. Kadowitz and Ben McNamera, 337-346, 2000.
96. Inscho, Edward W., John D. Imig and L. Gabriel Navar. Nonendothelial regulation of the renal microcirculation. In: Advances in Organ Biology: The Renal Circulation, Edited by Warwick P. Anderson, Volume 9: 219-233, 2000.
97. Inscho, Edward W. The in vitro blood perfused juxtamedullary nephron technique. Edited by Donna H. Wang, Published by Humana Press Inc. Totowa, NJ. In Methods in Molecular Medicine 51: Chapter 30; 435-449, 2000
98. Inscho, Edward W. Frontiers in Physiology: A joint meeting of the Scandinavian and American Physiological Societies. The Physiologist 43: 470-471, 2000.
99. Inscho, Edward W. Renal microvascular effects of P2 receptor stimulation. Clinical and Experimental Pharmacology and Physiology 28: 332-339, 2001.
100. Inscho, Edward W. Extracellular ATP and cAMP as paracrine and inter-organ regulators of renal function. Clinical and Experimental Pharmacology and Physiology 28: 331, 2001.
101. Inscho, Edward W. P2 receptors in the regulation of the renal microvascular function. American Journal of Physiology: Renal Physiology 280: F927-F944, 2001.
102. Imig, John D. and Edward W. Inscho. Adaptations of the renal microcirculation to hypertension. Microcirculation 9: 315-328, 2002.
103. Inscho, Edward W. Purinergic receptors in the glomerulus and vasculature of the kidney. In: Current Topics in Membrane Biology, Edited by Erik M. Schwiebert, 54: 453-478, 2003.
104. Inscho, Edward W. Modulation of renal microvascular function by adenosine. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 285: R23-R25, 2003.
105. Inscho, Edward W., Anthony K. Cook, John D. Imig, Catherine Vial, and Richard J. Evans. Renal autoregulation in P2X1 knockout mice. Acta Physiologica Scandinavica 181: 445-453, 2004.
106. Nishiyama, Akira and Edward W. Inscho. Role of interstitial ATP and adenosine in the regulation of renal hemodynamics and microvascular function. Hypertension Research 27: 791-804, 2004.
107. Webb, R. Clinton and Edward W. Inscho. Age-related changes in the cardiovascular system. In: Hypertension in the Elderly, ed by LM. Prisant, Humana Totowa, New Jersey, pp11-21, 2005.
108. Guan, Zhengrong, David A. Osmond and Edward W. Inscho. Purinoceptors in the kidney. Experimental Biology and Medicine 232 (6): 715-726, 2007.
109. Guan, Zhengrong, David A. Osmond and Edward W. Inscho. P2X receptors as regulators of the renal microvasculature. Trends in Pharmacological Sciences 28 (12): 646–652, 2007.
110. Inscho, Edward W., Purinergic factors regulating renal microcirculation. The Renal Microcirculation. In The Handbook of Physiology: Microcirculation. Edited by Ronald F. Tuma, Walter N. Duran and Klaus Ley. Elsevier, San Diego, Calif., pp550 – 683, 2008
111. Inscho, Edward W. ATP, P2 receptors and the renal microcirculation. Purinergic Signalling 5(4): 447-460, 2009. PMCID: PMC2776135
112. Inscho, Edward W., Mysteries of autoregulation. Hypertension 53: 299-306, 2009. PMCID: PMC2690861
113. Inscho, Edward W. Purinoceptor regulation of renal tubular transport is coming of age. Invited Editorial Focus, American Journal of Physiology: Renal Physiology 297: F1166-F1167, 2009. PMCID: PMC2781337
114. Peti-Peterdi, Janos., L. Gabriel Navar, P. Darwin Bell, Daniel Casellas, Pamela K. Carmines, Edward W. Inscho, Suzanne Oparil. A true champion of Hungarian kidney research and nephrology education – Tribute to László Rosivall. Acta Physiologica Hungarica, 96 (3): 375–382, 2009.
115. Guan, Zhengrong, Jennifer S. Pollock, Anthony K. Cook, Janet L. Hobbs and Edward W. Inscho. Response to: Role of epithelial sodium channels in the renal myogenic response. Hypertension 55: e8-e9, 2010. Published online Dec 28, 2009. Letter to the Editor.
116. Navar, L. G., William J. Arendshorst, Thomas J. Pallone, Edward W. Inscho, John D. Imig, and P. Darwin Bell. The Renal Microcirculation. Published in Comprehensive Physiology. 550–683, 2011.
117. Kohan, Donald E., Noreen F. Rossi, Edward W. Inscho, and David M. Pollock. Regulation of blood pressure and salt homeostasis by endothelin. Physiological Reviews 91: 1-77, 2011. PMCID: PMC3236687
118. Kohan, Donald E; Edward W. Inscho, Donald Wesson and David M. Pollock. Physiology of endothelin and the kidney" Handbook of Renal Physiology now called Comprehensive Physiology 1(2): 883-919, 2011. PMCID:PMC3940435
119. Guan, Zhengrong and Edward W. Inscho. Endothelin and the renal vasculature. Contributions to Nephrology 172:35-49, 2011. PMCID: PMC3236641
120. Guan, Zhengrong and Edward W. Inscho. Role of adenosine-5’-triphosphate in regulating renal microvascular function and in hypertension. Hypertension 58(3): 333-40, 2011. PMCID: PMC3730531.
121. Guan, Zhengrong, Robert C. Fellner, Justin Van Beusecum, Edward W. Inscho. P2 receptors in renal autoregulation. Current Vascular Pharmacology 12: 818-828, 2014. Final Galley revisions were sent to the journal 12-1-14. PMCID: PMC3965657.
122. Van Beusecum, Justin, Edward W. Inscho. Regulation of renal function and blood pressure control by P2 purinoceptors in the kidney. Current Opinion in Pharmacology 21: 82-88, 2015. PMCID: PMC5515225.
123. Guan, Zhengrong, Justin P. Van Beusecum and Edward W. Inscho. Endothelin and the renal microcirculation. Seminars in Nephrology 35 (2): 145-155, 2015. PMCID: PMC5221560.
124. Bosetti, Francesca, Zorina S. Galis, Margaret S. Bynoe, Marc Charette, Marilyn J. Cipolla, Gregory J. del Zoppo, Douglas Gould, Thomas S. Hatsukami, Teresa L. Z. Jones, James I. Koenig, Gerard A. Lutty, Christine Maric‐Bilkan, Troy Stevens, H. Eser Tolunay, Walter Koroshetz, the “Small Blood Vessels: Big Health Problems” Workshop Participants, Dritan Agalliu, David A. Antonetti, Manfred Boehm, Claudette E. Brooks, Kathleen M. Caron, William Chilian, Mat J. Daemen, Robert D'Amato, Thomas P. Davis, Adviye Ergul, James E. Faber, Ariel R. Gomez, Peter Grayson, Isabella Grumbach, Jaime Grutzendler, Chenghua Gu, David Gutterman, John Hallenbeck, Ira Herman, Jay Humphrey, Costantino Iadecola, Edward W. Inscho, David Kleinfeld, Eng H. Lo, Jose A. Lopez, Stephen Macknik, Asrar Malik, Tanya N. Mayadas, Dorian McGavern, Gerald A. Meininger, Virginia M. Miller, Maiken Nedergaard, Mark T. Nelson, Shayn Peirce‐Cottler, Ipolia Ramadan, Gary A. Rosenberg, Ernesto L. Schiffrin, Peter Searson, Nina Stachenfeld, Radu V. Stan, Yajaira Suarez, Eroboghene E. Ubogu, Zinaida S. Vexler, Cornelia M. Weyand and Berislav V. Zlokovic. Small Blood Vessels: Big Health problems?: Scientific Recommendations of the NIH Workshop. Journal of the American Heart Association 5: e004389, 2016. PMCID: PMC5210346
125. Vallon, Volker, Robert Unwin, Edward W. Inscho, Jens Leipziger, and Bellamkonda K. Kishore. Extracellular Nucleotides and P2 Receptors in Renal Function. Physiological Reviews, 100: 211-269, 2020. PMCID: PMCID: PMC6985785.
126. Guan, Zhengrong, Mirhan A. Makled and Edward W. Inscho. Purinoceptors, Renal Microvascular Function and Hypertension. Submitted to Physiological Research, 3/12/2020. PMCID: Pending: Available April 1, 20201.
127. Gohar, PhD, Eman, Malgorzata Kasztan, PhD; Shali Zhang; Edward W Inscho, PhD; David M Pollock, PhD. Role for ovarian hormones in purinoceptor-dependent natriuresis. Biology of Sex Differences , 2020.
128.
ABSTRACTS:
1. Glogar, Dietmar H., Leland C. Clark, Jr., Robert A. Kloner, Edward W. Inscho, Laurence W.V. DeBoer, James Tumas, James Muller and Eugene Braunwald. Fluorocarbons: Increase oxygen delivery and limitation of infarct size. Clinical Research, 28: 612A, 1980.
2. Banks, Robert O., Edward W. Inscho and Eugene D. Jacobson. Histamine H2 receptors and renal autoregulation. Federation Proc. 41: 1257, 1982.
3. Inscho, Edward W., William W. Wilfinger and Robert O. Banks. Localization of atrial natriuretic factor (ANF) in dispersed rat atrial cell populations. Federation Proc. 43: 500, 1984.
4. Inscho, Edward W., Robert O. Banks and William W. Wilfinger. Ontogeny of atrial natriuretic activity in rats. 67th Annual Meeting of the Endocrine Society, 1985.
5. Inscho, Edward W., William W. Wilfinger and Robert O. Banks. The effect of age on the biological properties of crude and fractionated rat atrial extracts. Kidney International 29: 248, 1986.
6. Inscho, Edward W., Pamela K. Carmines, Anthony K. Cook and L. Gabriel Navar. Interaction between prostaglandin E2 and angiotensin II in the regulation of afferent arteriolar diameter. FASEB Journal 3: 8541, 1989.
7. Inscho, Edward W., Anthony K. Cook, Pamela K. Carmines and L. Gabriel Navar. Direct assessment of afferent arteriolar responsiveness in the nonclipped kidney of Goldblatt hypertensive rats. Hypertension 14: 335, 1989.
8. Inscho, Edward W., Pamela K. Carmines, Anthony K. Cook and L. Gabriel Navar. The effect of prostacyclin (PGI2) on afferent arteriolar diameter changes induced by vasoconstrictor agents. Kidney International 37: 552, 1990.
9. Inscho, Edward W., Pamela K. Carmines and L. Gabriel Navar. Differential effects of prostaglandins E2 and I2 on afferent arteriolar vasoconstrictor responses. Proc. XIth International Congress of Nephrology: 284A, 1990.
10. Inscho, Edward W., Pamela K. Carmines and L. Gabriel Navar. Differential stimulation of afferent arterioles by 2-chloroadenosine and ATP. Hypertension 16: 328, 1990.
11. Ibarrola, A. Mariano, Edward W. Inscho, Richard C. Vari and L. Gabriel Navar. Maintenance of renal autoregulatory capability during adenosine receptor blockade. Physiologist 33: A94, 1990.
12. Ortenberg, Joseph M., Anthony K. Cook, Pamela K. Carmines, Edward W. Inscho and L. Gabriel Navar. Attenuated afferent arteriolar response to acetylcholine in 2K1C Goldblatt hypertension. Journal of the American Society of Nephrology 1: 497, 1990.
13. Inscho, Edward W., Pamela K. Carmines and L. Gabriel Navar. P2 purinergic stimulation of rat juxtamedullary afferent arteriolar vasoconstriction. Clinical Research 38: 767A, 1990.
14. Ortenberg, Joseph M., Anthony K. Cook, Pamela K. Carmines, and Edward W. Inscho. Afferent arteriolar vasodilator responses to acetylcholine in 2K1C Goldblatt hypertension. Clinical Research 38: 767A, 1990.
15. Inscho, Edward W., Pamela K. Carmines, Anthony K. Cook, and L. Gabriel Navar. Afferent arteriolar responses to purinergic agonists during adenosine receptor blockade. FASEB Journal 5: A378, 1991.
16. Carmines, Pamela K., Edward W. Inscho, Joseph M. Ortenberg and Anthony K. Cook. Perfusate composition modulates renal microvascular responses to perfusion pressure alterations in a segment specific manner. FASEB Journal 5: A378, 1991.
17. Ortenberg, Joseph M., Anthony K. Cook, Edward W. Inscho and Pamela K. Carmines. Acetylcholine-induced afferent arteriolar vasodilation is attenuated in Goldblatt hypertension. Hypertension 18: 414, 1991.
18. Ohishi, Kazuhisa, Pamela K. Carmines, Edward W. Inscho and L. Gabriel Navar. Nitro-L-arginine effects on juxtamedullary afferent arterioles: Modulation by enalaprilat. Journal of the American Society of Nephrology 2: 525, 1991.
19. Inscho, Edward W. and L. Gabriel Navar. Effect of ATP on pre- and post-glomerular microvasculature: Predominant afferent site of action. Journal of the American Society of Nephrology 2: 525, 1991.
20. Ohishi, Kazuhisa, Pamela K. Carmines, Edward W. Inscho and L. Gabriel Navar. Effect of EDRF blockade on juxtamedullary afferent arterioles and modulation by angiotensin II. Clinical Research 39: 847A, 1991.
21. Inscho, Edward W., Kazuhisa Ohishi, Todd P. Belott and L. Gabriel Navar. Effect of EDRF blockade on the response of juxtamedullary afferent arterioles to ATP stimulation. FASEB Journal 6: A5066, 1992.
22. Ohishi, Kazuhisa, Pamela K. Carmines, Edward W. Inscho and L. Gabriel Navar. Effect of Dup 753 on afferent and efferent arteriolar constrictor responses to EDRF blockade. FASEB Journal 6: A251, 1992.
23. Carmines, Pamela K., Anthony K. Cook and Edward W. Inscho. Adenosine receptor blockade does not alter arteriolar angiotensin II responsiveness in the rat. Am. Soc. Nephrol. 3: 559, 1992.
24. Inscho, Edward W. and L. Gabriel Navar. Effect of calcium channel blockade on ATP-mediated afferent arteriolar vasoconstriction. Journal of the American Society of Nephrology 3: 564, 1992.
25. Inscho, Edward W., Todd P. Belott, Michael J. Mason and L. Gabriel Navar. Extracellular ATP increases cytosolic calcium in renal vascular smooth muscle cells. Physiologist 35: A-10, 1992.
26. Inscho, Edward W., Todd P. Belott and Michael J. Mason. Mechanisms of extracellular ATP stimulated elevation of cytosolic calcium in renal vascular smooth muscle cells. FASEB Journal 7: A758, 1993.
27. Ruiz-Velasco, J. Victor, M. Beatriz Mayer, Edward W. Inscho and Lin J. Hymel. Modulation of dihydropyridine (DHP) binding sites in vascular smooth muscle cells (VSMC) by membrane potential and cell growth. FASEB Journal 7: A47, 1993.
28. Inscho, Edward W., Todd P. Belott and Michael J. Mason. Mechanisms of extracellular ATP stimulated elevation of cytosolic calcium in renal arterial smooth muscle cells (VSMC). IUPS Meeting, 1993.
29. Carmines, Pamela K., Edward W. Inscho and Lisa M. Harrison-Bernard. Modulation of the vasoconstrictor influences of angiotensin II on renal arterioles. IUPS meeting 1993.
30. Navar L. Gabriel, Edward W. Inscho and Kenneth D. Mitchell. Effects of extracellular ATP on renal microvascular function and tubuloglomerular feedback. IUPS meeting 1993.
31. Takenaka, Tsuneo, Lisa M. Harrison-Bernard, Edward W. Inscho and L. Gabriel Navar. Mechanistic components of afferent arteriolar blood flow autoregulation in blood perfused juxtamedullary nephrons. Journal of the American Society of Nephrology 4: 588, 1993.
32. Inscho, Edward W. and L. Gabriel Navar. P2-purinoceptor desensitization attenuates autoregulatory behavior in rat juxtamedullary afferent arterioles. Journal of the American Society of Nephrology 4: 581, 1993.
33. Cook, Anthony K., Lisa M. Harrison-Bernard, Edward W. Inscho and L. Gabriel Navar. Differential reactivity along juxtamedullary afferent arterioles to angiotensin II (Ang II). FASEB Journal 8: A583, 1994.
34. Majid, Dewan S. A., Edward W. Inscho and L. Gabriel Navar. Impairment of renal blood flow autoregulation during purinoceptor saturation by ATP in dogs. Journal of the American Society of Nephrology 5: 606, 1994.
35. Inscho, Edward W., L. Gabriel Navar and Anthony K. Cook. P2-purinoceptor saturation attenuates autoregulatory behavior in rat juxtamedullary afferent arterioles. Journal of the American Society of Nephrology 5: 605, 1994.
36. Inscho, Edward W., Michael J. Mason, Alan C. Schroeder, Karl D. Stiegler and John D. Imig. Freshly isolated renal microvascular smooth muscle cell responses to KCl depolarization. FASEB Journal 9: A610, 1995.
37. Inscho, Edward W., L. Gabriel Navar and Anthony K. Cook. P2-purinoceptor inhibition with pyridoxal-phosphate-6-azophenyl-2',4'-disulphonic acid (PPADS) blocks autoregulatory behavior in juxtamedullary afferent arterioles. Journal of the American Society of Nephrology 6: 652, 1995.
38. Inscho, Edward W. and Anthony K. Cook. P2-purinoceptor characterization in rat juxtamedullary afferent arterioles. FASEB Journal 10: A371, 1996.
39. Inscho, Edward W. and Anthony K. Cook. The role of calcium release from intracellular stores on the afferent and efferent arteriolar response to angiotensin II. Hypertension 28: P98, 1996.
40. Ichihara, Atsuhiro, Edward W. Inscho, John D. Imig and L. Gabriel Navar. Effects of chronic renal denervation on the enhanced afferent arteriolar reactivity in angiotensin II-induced hypertension. Hypertension 28: P101, 1996.
41. Ichihara, Atsuhiro, Edward W. Inscho, and L. Gabriel Navar. Influence of nitric oxide levels on afferent arteriolar responses to angiotensin II. Journal of the American Society of Nephrology 7: A1567, 1996.
42. Inscho, Edward W. and John D. Imig. Extracellular ATP increases cytosolic Ca2+ concentration of freshly isolated renal microvascular smooth muscle cells. Journal of the American Society of Nephrology 7: A2154, 1996.
43. Inscho, Edward W., Paul C. Deichmann and John D. Imig. Extracellular ATP increases cytosolic Ca2+ concentration of freshly isolated renal microvascular smooth muscle cells (MVSMC). Microcirculation 4: 158, 1997.
44. Inscho, Edward W., Paul C. Deichmann and John D. Imig. ATP increases cytosolic Ca2+ concentration in renal microvascular smooth muscle cells (MVSMC) through a thapsigargin-insensitive pathway. FASEB Journal 11: A504, 1997.
45. Imig, John D., Anthony K. Cook and Edward W. Inscho. Postglomerular vasoconstriction to angiotensin and norepinephrine depend on release of Ca2+ from intracellular stores. Microcirculation 4: 182, 1997.
46. Walker, Matthew, Edward W. Inscho and L. Gabriel Navar. An assessment of stability in the autoregulation of afferent arteriolar diameter using angiotensin II and candesartan (CV): A control theory computer model. FASEB Journal 11: A85, 1997.
47. Ichihara, Atsuhiro, John D. Imig, Edward W. Inscho and L. Gabriel Navar. Macula densa derived neuronal nitric oxide synthase (nNOS) impacts renal arteriolar diameter. Microcirculation 4: 162, 1997.
48. Ichihara, Atsuhiro, Edward W. Inscho, John D. Imig and L. Gabriel Navar. Neuronal nitric oxide synthase (nNOS) enhances efferent but not afferent arteriolar reactivity to angiotensin II (ANG II). FASEB Journal 11: A10, 1997.
49. Walker III, Matthew, Edward W. Inscho, Anthony K. Cook and L. Gabriel Navar. Influence of angiotensin II on the autoregulatory stability of afferent arteriolar diameter. Microcirculation 4: 157, 1997.
50. Shah, M. K., David G. Lambert, Hunter C. Champion, Mark A. Czapla, B. J. Dewitt, Edward W. Inscho and Philip J. Kadowitz. Vascular responses to α, β-methylene ATP in the cat. FASEB Journal 11: A504, 1997.
51. Lambert, David G., M. K. Shah, Hunter C. Champion, Mark A. Czapla, Edward W. Inscho and Philip J. Kadowitz. ATP and UTP have novel cAMP-mediated vasodilator activity in the hindlimb vascular bed of the cat. FASEB Journal 11: A503, 1997.
52. Inscho, Edward, W. Anthony K. Cook and John D. Imig. Release of calcium from intracellular stores contributes to the afferent arteriolar response to alterations in perfusion pressure. Hypertension, 30: 474, 1997.
53. Ichihara, Atsuhiro, John D. Imig, Edward W. Inscho and L. Gabriel Navar. Nitric oxide counteracts afferent but not efferent arteriolar reactivity to angiotensin II in angiotensin II-induced hypertension. Hypertension, 488, 1997.
54. Inscho, Edward, W., John D. Imig, Anthony K. Cook, Paul C. Deichmann and Vy Mui. Preglomerular vasoconstriction by ATP involves mobilization of Ca2+ from a caffeine-sensitive intracellular source. Journal of the American Society of Nephrology 8: 331A, 1997.
55. Ichihara, Atsuhiro, John D. Imig, Edward W. Inscho and L. Gabriel Navar. Cyclooxygenase-2 (COX2) participates in tubular flow-dependent regulation of afferent arteriolar tone. Journal of the American Society of Nephrology 8: 331A, 1997.
56. Ichihara, Atsuhiro, Edward W. Inscho, John D. Imig and L. Gabriel Navar. Perfusion pressure dependent augmentation of afferent arteriolar vasoconstriction to increased distal nephron volume delivery. FASEB Journal 12: A996, 1998.
57. Inscho, Edward W., John D. Imig, Paul C. Deichmann and Anthony K. Cook. Candesartan protects against loss of autoregulatory efficiency in angiotensin II- infused rats. Presented at the Submitted to Astra sponsored Workshop on "Function and Clinical Perspectives of Angiotensin AT1 receptors: Cardiovascular and Renal Function in Health and Disease"; Budapest, Hungary; 1998.
58. Inscho, Edward W. and John D. Imig. Isolated preglomerular microvascular smooth muscle cells exhibit marked increases in intracellular Ca2+ in response to P2Y receptor stimulation. Hypertension 32: 615, 1998.
59. Imig, John D., Edward W. Inscho, Paul C. Deichmann and John R. Falck. Afferent arteriolar vasodilation to 11,12-epoxyeicosatrienoic acid (11,12-EET) involves activation of protein kinase A. Hypertension 32: 592, 1998.
60. Ichihara, Atsuhiro, John D. Imig, Edward W. Inscho and L. Gabriel Navar. Neuronal nitric oxide synthase-mediated regulation of afferent arteriolar diameter is reduced in angiotensin II-induced hypertension. Hypertension 32: 599, 1998.
61. Inscho, Edward W., John D. Imig, Paul C. Deichmann and Anthony K. Cook. Candesartan-cilexetil preserves autoregulatory efficiency in angiotensin II (Ang II) infused rats. Journal of the American Society of Nephrology 9: 308A, 1998.
62. Inscho, Edward W. and Anthony K. Cook. Effect of calcium channel blockade on UTP-mediated afferent arteriolar vasoconstriction. FASEB Journal 14: A718, 1999.
63. Inscho, Edward W., John D. Imig, Alan C. Schroeder and David M. Pollock. Endothelin-mediated calcium signaling in preglomerular smooth muscle cells (MVSMC). Hypertension 34: 335, 1999.
64. Imig, John D. and Edward W. Inscho. Cytochrome P450 hydroxylase metabolites influence the intracellular calcium and afferent arteriolar vasoconstrictor responses to endothelin-1. Hypertension 34: 366, 1999.
65. Inscho, Edward W. The role of P2 purinoceptor activation on renal microvascular function. American Heart Association Research Symposium: Dallas, Texas, 1999.
66. Inscho. Edward W. and L. Gabriel Navar. Calcium signaling in renal microvascular smooth muscle responses to P2 purinoceptor stimulation. Journal of Vascular Research 36: 421, 1999.
67. Inscho, Edward W., John D. Imig and Anthony K. Cook. Effect of Candesartan-cilexetil intervention on autoregulatory efficiency in angiotensin II-infused hypertensive rats. Presented at the Angiotensin II Receptor Blockade: Effects Beyond Blood Pressure Control meeting in Prague, Czech Republic, June 14-17, 2000 sponsored by Astra Zeneca.
68. White, Steven M., John D. Imig, and Edward W. Inscho. Calcium signaling pathways utilized by P2X receptors in preglomerular vascular smooth muscle cells. Southern regional meeting of the American Federation for Medical Research, New Orleans, February 17-19, 2000.
69. White, Steven M., John D. Imig, and Edward W. Inscho. Calcium signaling pathways utilized by P2X receptors in preglomerular vascular smooth muscle cells (MVSMC). FASEB Journal 14: A136, 2000.
70. Imig, John D., S. S. Yiu, Elizabeth LeBlanc and Edward W. Inscho. Afferent arteriolar vasoconstriction to 12-hydroxyeicosatetraenoic acid [12(S)-HETE] involves activation of L-type calcium channels. FASEB Journal 14: A574, 2000.
71. Inscho, Edward W. and Anthony K. Cook. P2X1 receptor blockade inhibits pressure-induced afferent arteriolar autoregulatory behavior. Hypertension 36: 26, 2000.
72. Zhao, Xueying, John R. Falck, Edward W. Inscho and John D. Imig. Contribution of the cytochrome P450 hydroxylase pathway to P2 purinoceptor-mediated afferent arteriolar vasoconstriction. Journal of the American Society of Nephrology 11: A1916, 2000.
73. Nishiyama, Akira, Edward W. Inscho and L. Gabriel Navar. The interactive role of A1 and A2a receptors on afferent and efferent arteriolar reactivity in rats. Journal of the American Society of Nephrology 11: A1899, 2000.
74. Inscho, Edward W. and Anthony K. Cook. P2X1 receptor blockade inhibits pressure-induced afferent arteriolar autoregulatory behavior in rat kidneys. Presented at the Joint American Physiological Society and Scandinavian Physiological Meeting in Stockholm, Sweden August 16-19, 2000.
75. Inscho, Edward W. Anthony K. Cook, John D. Imig and David M. Pollock. Afferent and efferent arteriolar responses to endothelin are predominantly mediated by activation of ETA receptors. FASEB J. 15: A149, 2001.
76. Jenkins, John M., Edward W. Inscho and David M. Pollock. Role of L-type calcium channels in the renal vasoconstrictor response to sarafotoxin 6c. FASEB J. 16: A474, 2002.
77. Inscho, Edward W. and Anthony K. Cook. Autoregulatory responses are maintained during adenosine A1 receptor blockade with DPCPX. FASEB J. 16: A475, 2002.
78. Inscho, Edward W., Anthony K. Cook, and John D. Imig. Aging impairs renal autoregulatory efficiency in male Fisher344/Brown Norway rats. FASEB J. 16: A869, 2002.
79. Inscho, Edward W., Anthony K. Cook, and John D. Imig. Effect of aging and gender on the afferent arteriolar response to endothelin in Fisher344/Brown Norway Rats. FASEB J. 16: A869, 2002.
80. Imig, John D., Benjamin C. Hauschild, Thuy T. Kim, Xueying Zhao, John R. Falck and Edward W. Inscho. P2X receptor stimulated calcium responses in preglomerular vascular smooth muscle cells FASEB J. 16: A128, 2002.
81. Sullivan, Jennifer, C., Matthew Collins, John D. Imig, Edward W, Inscho and Jennifer S. Pollock The effects of age and gender on NOS activity and expression in mesenteric arteries. FASEB J. 16: A826, 2002.
82. Inscho, Edward W., John D. Imig, David M. Pollock and Anthony K. Cook. ETA and ETB receptors participate in the afferent arteriolar response to endothelin. FASEB J. 16: A130, 2002.
83. Zhao, Xueying, Edward W. Inscho, Christopher Morisseau, Bruce D. Hammock, and John D. Imig. Soluble epoxide hydrolase regulates renal microvascular angiotensin II reactivity in hypertension. FASEB J. 16: A418, 2002.
84. Inscho, Edward W. and Anthony K. Cook. P2X1 receptor blockade inhibits pressure-induced afferent arteriolar autoregulatory behavior in rat kidneys. Oral Presentation at the 7th International Symposium on Adenosine and Adenine Nucleotides, Gold Coast, Queensland, Australia. May 25-31, 2002.
85. Inscho, Edward W. and Anthony K. Cook. P2 receptors mediate pressure-induced afferent arteriolar (AA) autoregulatory behavior. 4th International Congress of Pathophysiology, Budapest, Hungary, June 29-July 5, 2002. Acta Physiologica Hungarica 89 (1-3): 104, 2002.
86. Inscho, Edward W., Anthony K. Cook and Kumar Sharma. TGF-β Inhibits pressure-induced afferent arteriolar autoregulatory behavior. Hypertension 40: 379, 2002.
87. Sullivan C. Jennifer, Elizabeth Dabbs Loomis, John D. Imig, Edward W. Inscho and Jennifer Pollock. Advancing age is associated with a decrease in stimulated NO production and an increase in oxidative stress. Hypertension 40: 430, 2002.
88. Zhao, Xueying, David M. Pollock, Edward W. Inscho and John D. Imig. Decreased renal CYP2C enzymes and impaired endothelium-dependent dilation are associated with angiotensin II salt-sensitive hypertension. Hypertension 40: 425, 2002.
89. Daniels, Ericka R., Kanchan A. Chitaley, Anna E. Kozak, Michael W. Brands, John D. Imig, Edward W. Inscho, Wieslaw Kozak, David M. Pollock and R. Clinton Webb. Interleukin-6 is required for the chronic phase of angiotensin II-induced hypertension in mice. Hypertension 40: 400, 2002.
90. Kolbeck, Ralph C., Edward W. Inscho and Michael W. Brands. Medical student class-personality: It’s influence on learning. International Association of Medical Science Educators Meeting, 2002.
91. Sharma, Kumar, Anthony K. Cook and Edward W. Inscho. TGF-β inhibits pressure-induced afferent arteriolar autoregulatory behavior. J. Am. Soc. Nephrol. 13, 76P, 2002.
92. Inscho, Edward W., Anthony K. Cook, Catherine Vial and Richard J. Evans. Pressure-induced autoregulatory responses are inhibited in mice lacking P2X1 receptors. FASEB J. 17: A103, 2003.
93. Zhang, Zhanying, Xueying Zhao, John D. Imig, Edward W. Inscho. Expression and distribution of P2X1, P2X4, and P2Y1 purinoceptors by western blot analysis in rat kidneys. FASEB J. 17: A926, 2003.
94. Inscho, Edward W., Anthony K. Cook, James Murzynowski and John D. Imig. Elevated arterial pressure impairs autoregulatory capability independently of AT1 receptors. Inter-American Society of Hypertension meeting, 2003.
95. Inscho, Edward W, Anthony K. Cook and R. Clinton Webb. Rho-kinase inhibition reduces pressure-mediated autoregulatory adjustments in afferent arteriolar diameter. Hypertension 42: 388, 2003.
96. Inscho, Edward W., Anthony K. Cook, Matthew Smith and Kumar Sharma. TGF-beta inhibits pressure-induced afferent arteriolar autoregulatory behavior by stimulating superoxide generation. Hypertension 42: 394, 2003.
97. Inscho, Edward W., Anthony K. Cook, Catherine Vial and Richard J. Evans. Pressure-induced autoregulatory responses are inhibited in mice lacking P2X1 receptors. The Physiologist 46 (4): 244, 2003.
98. Sharma, K., Matthew Smith, Anthony K. Cook and Edward W Inscho. TGF-beta inhibits pressure-induced afferent autoregulatory behavior by stimulating superoxide generation, J. Am. Soc. Nephrol. 14: 605A, 2003.
99. Inscho, Edward W., John D. Imig, Xueying Zhao, Anthony K. Cook and Brentan M. Edwards. Purinoceptor-mediated vasoconstriction of afferent arterioles is attenuated in Ang II-dependent hypertension. FASEB J. 18: A288, 2004.
100. Zhao, Xueying, Edward W. Inscho, Jeffrey E. Quigley, Constantine Z. Zaharis and John D. Imig. Purinoceptor-mediated calcium signaling is attenuated in preglomerular smooth muscle cells during Ang II salt-sensitive hypertension. FASEB J. 18: A293, 2004.
101. Sullivan, Jennifer C., Jennifer M. Sasser, John D. Imig, Edward W Inscho, Jennifer S. Pollock. Age-related alterations in NOS3 phosphorylation and oxidative stress in mesenteric arteries. Presented at the 12th International Conference on Second Messengers and Phosphoproteins; 2004.
102. Inscho, Edward W., Anthony K. Cook, John D. Imig, Catherine Vial and Richard J. Evans. Renal Autoregulation in P2X1 Knockout Mice. Presented at the Purines 2004 meeting.
103. Inscho, Edward W. The role of purinergic receptors along the renal microvasculature. Presented at the Physiological Society Symposium in Cork Ireland; 2004.
104. Rivera, Ian M., Barry S. Fuller, Shali Zhang, Brentan M. Edwards, Seán M. Shaw, Mario B. Marrero and Edward W. Inscho. P2 receptor regulation of intracellular calcium concentration in cultured mouse mesangial cells. FASEB J. 19: A1142, 2005.
105. Fuller, Andrew J., Benjamin C. Hauschild, Mohammad Awayda, R. Gonzalas-Villalobos, John D. Imig, Edward W. Inscho and Luis G. Navar. Early activation of calcium and chloride channels by angiotensin II receptors in preglomerular smooth muscle cells. FASEB J. 19: A1148, 2005.
106. Inscho, Edward W., John D. Imig, Anthony K. Cook and David M. Pollock. ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin. Accepted for the ET-9 meeting in Salt Lake City, Utah September 11-14, 2005.
107. Inscho, Edward W. Anthony K. Cook, Shali Zhang, David A. Osmond. P2X1 receptor-mediated vasoconstriction of afferent arterioles in Ang II hypertensive rats fed a high salt diet. Hypertension 46: 818, 2005.
108. Schneider, Markus Peter, Edward W Inscho, David M Pollock. Afferent arteriolar responses to endothelin-1 are attenuated by a high salt diet. FASEB J. 20: A758, 2006.
109. Inscho, Edward W. and Anthony K Cook. Deletion of IL-6 enhances renal microvascular autoregulatory responses and responses to purinoceptor activation. FASEB J. 20: A762, 2006.
110. Inscho, Edward W., Andrea Clarke, Shali Zhang, Crista Royal and David Osmond. P2 receptor mediated calcium signaling responses are impaired in preglomerular smooth muscle cells (PVSMC) of Ang II hypertensive rats fed a high salt diet. Hypertension 48: e44, 2006.
111. Giachini, Fernanda R. C., David A. Osmond, Romulo Leite, Juan Todd, Anthony K. Cook, Edward W. Inscho, R. Clinton Webb and Rita C. Tostes. Purinergic receptors and vascular smooth muscle function: focus on P2Y12. Presented at the 5th US/Japan Workshop on Molecular and Cellular Aspects of Vascular Smooth Muscle Function, January 2007.
112. Guan, Zhengrong, Anthony K. Cook and Edward W. Inscho Effect of ENaC blockade on the myogenic response of rat juxtamedullary afferent arterioles. FASEB Journal 21 (5), 2007.
113. Osmond, David A. and Edward W. Inscho. Impairment of renal autoregulatory behavior in Ang-II induced hypertension involves activation of P2Y12 receptors. MCG Graduate Student Research Day, 2007.
114. Guan, Zhengrong, Anthony K. Cook and Edward W. Inscho. Anti-inflammatory treatment prevented impairment of renal autoregulation induced by chronic Ang II-infusion. Presented at the 61st Council for High Blood Pressure Research Hypertension 50(4): P120; E119, 2007.
115. Osmond, David A. and Edward W. Inscho. Impairment of renal autoregulatory behavior in angiotensin II-induced hypertension is ameliorated by P2Y12 receptor blockade with clopidogrel. Presented at the 61st Council for High Blood Pressure Research Hypertension 50(4): P119; E118, 2007.
116. Osmond, David A. and Edward W. Inscho. P2 receptor blockade inhibits autoregulation of renal blood flow in vivo. FASEB Journal 22 (April) 761.11, 2008.
117. Inscho, Edward W. and Anthony K. Cook. High salt diet attenuates juxtamedullary afferent arteriolar autoregulatory behavior and responsiveness to P2X1 receptor stimulation. FASEB Journal 22 (April), 761.13, 2008.
118. Inscho, Edward W., Zhengrong Guan and David A. Osmond. P2Y12 receptor blockade or anti-inflammatory treatment preserves renal microvascular function in hypertension. Presented at the Purines 2008 meeting in Copenhagan, Denmark, June 29-July 02, 2008.
119. Inscho, Edward W., R. Clinton Webb and Anthony K. Cook. Uridine adenosine tetraphosphate is a potent vasoconstrictor of rat juxtamedullary afferent arterioles. Hypertension 52: P281, 2008.
120. Guan, Zhengrong, Anthony K. Cook, Edward W. Inscho Mycophenolate mofetil preserves afferent arteriolar autoregulatory behavior in Ang II-infused hypertensive rats. Hypertension 52: P020, 2008.
121. de Chantemèle, Eric J. Belin, Mario B Marrero, Kenjiro Muta, Brenda Lilly, Edward W Inscho, David Fulton, and David W. Stepp. Protein Tyrosine Phosphatase 1B (PTP1B) is a major regulatory pathway for leptin-mediated control of cardiovascular function. Jackson Cardiovascular-Renal Meeting 2008. Jackson, Mississippi, October 15-18, 2008
122. Guan, Zhengrong. David A. Osmond, Matt I. Giddens, Shali Zhang, Anthony K. Cook and Edward W. Inscho. Anti-inflammatory treatment prevents impairment of renal autoregulation in Ang II-induced hypertensive rats. Jackson Cardiovascular-Renal Meeting 2008. Jackson, Mississippi, October 15-18, 2008
123. Inscho, Edward W., R. Clinton Webb and Anthony K. Cook. Uridine adenosine tetraphosphate is a potent vasoconstrictor of rat juxtamedullary afferent arterioles. Jackson Cardiovascular-Renal Meeting 2008. Jackson, Mississippi, October 15-18, 2008
124. Guan, Zhengrong, Anthony K Cook, Edward W Inscho. Anti-inflammatory treatment improves renal autoregulation in DOCA-salt hypertensive rats. FASEB Journal 23 (April), 805.6, 2009.
125. de Chantemele, Eric J Belin, Mario B Marrero, Kenjiro Muta, Brenda Lilly, Edward W Inscho, David Fulton, David W Stepp. Protein tyrosine phosphatase 1B (PTP1B): a major regulator of leptin-mediated control of cardiovascular function. FASEB Journal 23 (April), 1017.4, 2009.
126. Socha, Matthew John, Marlina Manhiani, Kouros Motamed, John D Imig, Edward W Inscho. SPARC deficiency ameliorates renal damage resulting from angiotensin II and a high salt diet. FASEB Journal 23 (April), 604.1, 2009.
127. Inscho, Edward W., David M. Pollock Jennifer S. Pollock and Anthony K. Cook High salt diet attenuates afferent arteriolar autoregulatory efficiency behavior by enhanced ETB receptor activation. The Physiologist 52: #12.2, 30, 2009.
128. Inscho, Edward W. Inscho, David M. Pollock Jennifer S. Pollock and Anthony K. Cook. Attenuation of afferent arteriolar autoregulatory behavior by a high salt diet involves activation of ETB receptors. Hypertension 54: #009, e27, 2009.
129. Osmond, David A., Edward W. Inscho. P2X1 receptor blockade with IP5I inhibits whole kidney autoregulatory behavior in vivo. Hypertension 54: #P199, e70, 2009.
130. Guan, Zhengrong, David. A. Osmond, Matthew I. Giddens, Shali Zhang, Anthony K. Cook and Edward W. Inscho Preservation of renal autoregulation by mycophenolate mofetil in Ang II-infused hypertensive rats. Hypertension 54: #P178, e66, 2009.
131. Inscho, Edward W. and Anthony K. Cook. High salt diet-induced afferent arteriolar autoregulatory dysfunction is improved by acute antioxidant treatment. FASEB J April 6, 2010 24:1059.9.
132. Inscho, Edward W., Zhengrong Guan and David A. Osmond. Hypertension and renal stressors blunt renal microvascular autoregulatory behavior by reducing renal microvascular reactivity to P2X receptor activation. Presented to the Purines 2010 meeting in Barcelona Spain.
133. Inscho, Edward W., David M. Pollock Jennifer S. Pollock and Anthony K. Cook. The impact of a high salt diet on rat renal microvascular function. FASEB Summer Conference, Saxtons River Vermont, June 20-25, 2010.
134. Guan, Zhengrong, Matthew I. Giddens, David. A. Osmond, Anthony K. Cook, Shali Zhang, Jennifer S. Pollock and Edward W. Inscho. Anti-inflammatory treatment preserves renal autoregulation in Ang II-induced hypertensive rats via normalization of P2X1 receptor activation. Southern Translational Education and Research Conference Augusta Georgia, September 10-11, 2010.
135. Zhengrong Guan, Anthony K Cook, Shali Zhang, Edward W Inscho. Sphingosine-1-phosphate evokes unique segment specific vasoconstriction of the renal microvasculature. Hypertension 56: e54, 2010.
136. Guan, Zhengrong, Matthew I. Giddens, Anthony K. Cook, and Edward W. Inscho Sphingosine-1-phosphate evokes vasoconstriction of rat afferent arterioles via activation of S1P1 and S1P2 receptors. FASEB J March 17, 2011 25:665.24
137. Guan, Zhengrong, Sean T. Singletary, Anthony K. Cook and Edward W. Inscho. Role of purinoceptors in regulating afferent arteriolar diameter in DOCA-salt hypertensive rats. FASEB J March 29, 2012 26:690.10.
138. Guan, Zhengrong Guan, Sean T. Singletary, Anthony K. Cook and Edward W. Inscho, Activation of voltage-dependent l-type calcium channels and the rho kinase pathway are involved in S1P-induced vasoconstriction in rat juxtamedullary afferent arterioles. Hypertension. 2012;60:A491
139. Fellner, R.C., Giddens, M.I., and Inscho, E.W. Inhibition of NADPH oxidase improves renal autoregulation in rats fed a high salt diet. FASEB J April 9, 2013 27:1110.14.
140. Guan, Zhengrong, Sean T. Singletary, Justin Van Beusecum, Anthony K. Cook and Edward W. Inscho. Renal ischemia-reperfusion led to enhanced renal microvascular response to sphingosine-1-phosphate. FASEB J April 9, 2013 27:1110.18.
141. Guan, Zhengrong, Sean T. Singletary and Edward W. Inscho. Inhibition of Sphingosine-1-phosphate receptor 2 activation protects against renal ischemia-reperfusion injury via reduction of reactive oxygen species. Hypertension 62: A551, 2013.
142. Van Beusecum, Justin P., Anthony K. Cook, Shali Zhang, Styliani Goulopoulou, Zhengrong Guan and Edward W. Inscho. Acute Toll-like Receptor 4 activation by lipopolysaccharide attenuates afferent arteriolar autoregulatory behavior. Hypertension 62: A286, 2013.
143. Inscho, Edward W., David M. Pollock, Jennifer C. Sullivan and Shali Zhang. High Salt Diet Attenuates ET-1 Mediated Calcium Signaling Responses in Preglomerular Smooth Muscle Cells from WT and ETB Receptor-Deficient Rats. Presented at the ET-13 meeting in Japan, September 8-11, 2013. Life Sciences 93(25-26), page e16, 2013.
144. Inscho, Edward W., Robert C. Fellner and David M. Pollock. Apocynin improves autoregulation of renal blood flow and glomerular filtration rate in rats fed a high salt diet. Poster and oral presentation at the International Society of Nephrology Forefronts Symposium, Charleston, SC. March 6-9, 2014. Abstract Number: FF14C-0042
145. Van Beusecum, Justin, Anthony K. Cook, Shali Zhang and Edward W. Inscho. Acute activation of Toll-like Receptor 4 by lipopolysaccharide blunts afferent arteriolar autoregulatory behavior. Poster and oral presentation at the International Society of Nephrology Forefronts Symposium, Charleston, SC. March 6-9, 2014. Abstract Number: FF14C-0045.
146. Guan, Zhengrong and Edward W. Inscho. Contribution of reactive oxygen species and rho kinase in sphingosine-1-phosphate mediated afferent arteriolar vasoconstriction of ischemia-reperfusion rats. Council for High Blood Pressure Research Meeting, San Francisco, September 9-12, 2014.
147. Van Beusecum, Justin, Anthony K. Cook, Shali Zhang, R. Clinton Webb and Edward W. Inscho. Blockade of toll-like receptor 4 during acute lipopolysaccharide treatment preserves afferent arteriolar autoregulatory behavior. Presented at the Council for High Blood Pressure Research Meeting, San Francisco, September 9-12, 2014.
148. Kohan, Donald, Gabriele Gusella, Rajeev Rohatgi, Jing Zhou, Edward W. Inscho, Tsuigio Seki, Bellamkonda Kishore, Meghana Pandit. Integrated collecting duct response of cilia, polycystins, ATP, NO and ET-1 to flow. American Society of Nephrology meeting, Philadelphia, PA. November 11-16, 2014.
149. Dunn, Kadeshia N., Edward W. Inscho, Scott S.P. Wildman and Claire M. Peppiatt-Wildman. A novel role for renal NMDA receptors: regulation of the renal microcirculation. American Society of Nephrology meeting, Philadelphia, PA. November 11-16, 2014.
150. Guan, Zhengrong, Pollock, David M. and Inscho, Edward W. ETB receptors in high salt diet-induced decline of renal autoregulation in rats. Experimental Biology 2015 meeting in Boston Mass. March 28-April 1, 2015.
151. Jin, Chunhua Jin, Michal Mrug, Bradley K. Yoder, Robert A. Kesterson, Edward W, Inscho, and David M. Pollock. Age- and sex-dependent salt sensitivity in Pkhd1pck rats. Submitted to the American Society of Nephrology Meeting in San Diego November 2015.
152. Yoder, Bradley K., Erik B. Malarkey, Cheng Song, Robert A. Kesterson, Michal Mrug, Edward Inscho, and David Pollock. In vivo analysis of cilia function in the kidney and their connections to renal disease and physiology. Submitted to the FASEB Biology of Cilia and Flagella Conference. July 19 –24, 2015, In Snowmass, CO.
153. Van Beusecum, Justin, Anthony K Cook, Shali Zhang, Richard P Tobin, M. Karen Newell-Rogers, Edward W. Inscho. MHC Class II-associated invariant peptide (CLIP) antagonism during chronic lipopolysaccharide treatment preserves afferent arteriolar autoregulatory behavior. Council on Hypertension Meeting, Washington DC., September 6-19, 2015. Hypertension 66: AP056, 2015.
154. Van Beusecum, Justin; Anthony K Cook, Shali Zhang, Richard P Tobin, M. Karen Newell-Rogers, Edward W. Inscho. MHC Class II-associated invariant peptide (CLIP) antagonism during chronic lipopolysaccharide treatment preserves afferent arteriolar autoregulatory behavior. UAB 26th Annual Vascular Biology & Hypertension Symposium, September 24&25, 2015 Birmingham Alabama.
155. Van Beusecum, Justin, Anthony K Cook, Shali Zhang, Richard P Tobin, M. Karen Newell-Rogers, Edward W. Inscho. MHC Class II-associated invariant peptide (CLIP) antagonism during chronic lipopolysaccharide treatment preserves afferent arteriolar autoregulatory behavior. UAB Comprehensive Cardiovascular Care Center 4th Annual Symposium: Inflammation and Cardiovascular Disease. October 8-9, 2015
156. Inscho, Edward W., Michal Mrug, Anthony K. Cook, Robert A. Kesterson, David M. Pollock and Bradley K. Yoder. Sex-dependent impairment of renal microvascular function in the Pkhd1pck rat model of ARPKD. Experimental Biology 2016 meeting in San Diego Calif. April 2-6, 2016.
157. Van Beusecum, Justin, Anthony K Cook, Shali Zhang, Richard P Tobin, M. Karen Newell-Rogers, Edward W. Inscho. Intervention with VG1177, a MHC class II invariant peptide chain (CLIP) antagonist, restores afferent arteriolar autoregulatory behavior during chronic 14 day lipopolysaccharide treatment. Experimental Biology 2016 meeting in San Diego Calif. April 2-6, 2016.
158. Chen, Daian, Joshua S. Speed, Kelly A. Hyndman, Malgorzata Kasztan, Jermaine J. Johnston, Edward W. Inscho, Martin E. Young, David M. Pollock, Jennifer S. Pollock Evidence for endothelin regulation of bmal1 expression in the renal vasculature. Experimental Biology 2016 meeting in San Diego Calif. April 2-6, 2016.
159. Guan, Zhengrong, Haword Cha, Justin P Van Beusecum, Anthony K Cook, Edward W. Inscho. Suppressing hypertension preserves renal autoregulatory behavior and purinoceptor response in deoxycorticosterone acetate-salt (DOCA-salt) treated rats. Experimental Biology 2016 meeting in San Diego Calif. April 2-6, 2016.
160. Pollock, David M., Chunhua Jin, Anthony K. Cook, Robert A. Kesterson, Bradley K. Yoder, Michal Mrug, and Edward W. Inscho. Microvascular endothelial dysfunction in a rat model of autosomal recessive polycystic kidney disease. American Society of Nephrology meeting in Chicago IL, November 15-20, 2016.
161. Jin, Chunhua, Michal Mrug, Bradley K. Yoder, Robert A. Kesterson, Edward W. Inscho, and David M. Pollock. Age- and sex-differences in salt sensitivity and renal function in a rat model of autosomal recessive polycystic kidney disease. AHA Council on Hypertension Research meeting in Orlando, FL September 14-17, 2016.
162. Guan, Zhengrong Guan and Edward W. Inscho. Role of sphingosine-1-phosphate 2 receptor in renal microvascular function of renal ischemia-reperfusion rats. AHA Council on Hypertension Research meeting in Orlando, FL September 14-17, 2016.
163. Guan, Zhengrong, Chan Woo Ryoo and Edward W. Inscho. Administration of Tempol improves renal autoregulation in ischemia-reperfusion induced acute kidney injury. Experimental Biology 2017 meeting in Chicago, IL, April 22-26, 2017.
164. Guan, Zhengrong, Wenguang Feng, Ijeoma E. Obi, Jennifer S. Pollock, Paul W. Sanders, Edward W. Inscho. Chronic Tempol treatment preserves afferent arteriole autoregulation in renal ischemia-reperfusion rats. American Society of Nephrology meeting in New Orleans, LA, November 1-5, 2017.
165. Baty, Josh, Zhengrong Guan, Shali Zhang and Edward W. Inscho. Rho kinase inhibitor is involved in L-type voltage-dependent calcium channel pathway in vascular smooth muscle cells. National Council for Undergraduate Research (NCUR) 2018 meeting at the University of Central Oklahoma from April 4-7, 2018 in Edmond, OK
166. Guan, Zhengrong, Josh Baty, Shali Zhang and Edward W. Inscho. Rho kinase inhibitors are involved in l-type voltage-dependent calcium channel pathway in vascular smooth muscle cells. Submitted to the Experimental Biology 2018 meeting in San Diego, April 21-15, 2018.
167. Gohar, Eman Y., Malgorzata Kasztan, Shali Zhang, Edward W. Inscho and David M. Pollock. Purinoceptor-dependent Regulation of Sodium Excretion is Sexually Dimorphic. Submitted to the 2018 AHA Hypertension Scientific Sessions meeting in Chicago IL September 6-9, 2018.
168. Feng, Wenguang, Zhengrong Guan, Dongqi Xing, Xingsheng Li, Wei-zhong Ying, Edward W. Inscho and Paul W. Sanders. Haploinsufficiency of Transcription Factor ETS-1 Improves Renal Autoregulation in Dahl Salt Sensitive Rats. Submitted to the American Society of Nephrology meeting in San Diego CA, October 25-28, 2018.
169. Sedaka, Randee S., Mandy J. Croyle, Brad A. Yoder, Edward W. Inscho, Chunhua Jin, David M. Pollock, and Jennifer S. Pollock. Cilia disruption may regulate the renal inner medulla NOS pathway. Submitted to the American Society of Nephrology meeting in San Diego CA, October 25-28, 2018
170. Dunaway Luke S, Anthony K. Cook, David M. Pollock, Kelly A. Hyndman, Edward W. Inscho, Jennifer S. Pollock. High salt induces hdac1-dependent disruption of nitric oxide signaling in the renal microvasculature submitted to the International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide in at the Maths Institute (Oxford), Keble College (Oxford), Oxford University Museum of Natural History, September 16-20 2018
171. Freeman, Brian, Shali Zhang, Anthony K. Cook, and Edward W. Inscho. Inhibition of TLR4 Activation Prevents Renal Autoregulatory Impairment in Ang II Hypertensive Rats. Submitted to the Experimental Biology 2019 meeting November 14, 2018.
172. Guan, Zhengrong, Wenguang Feng, Colton E. Remedies, Stephen R. Aldous, and Edward W. Inscho. Acute Antioxidant Treatment Improves Afferent Arteriole Autoregulatory Behavior in Ischemia-Reperfusion Acute Kidney Injury Rats. Submitted to the Experimental Biology 2019 meeting November 14, 2018.
173. Dunaway Luke S, Anthony K. Cook, David M. Pollock, Kelly A. Hyndman, Edward W. Inscho, Jennifer S. Pollock. High Salt Diet Induces HDAC1-Dependent Disruption of Nitric Oxide Signaling in the Renal Microvasculature. Submitted to the Experimental Biology 2019 meeting November 14, 2018.
174. Guan, Zhengrong, Wenguang Feng, Colton E. Remedies, Bailey A. McEachen, Paul W. Sanders, and Edward W. Inscho. Tempol Improves Renal Autoregulation and Kidney Function Following Ischemia-Reperfusion Injury in Rats. Submitted to the Experimental Biology 2020 meeting January 29, 2020.
175. Makled, Mirhan N., Wenguang Feng, Edward W. Inscho, Zhengrong Guan. Renal Ischemia-Reperfusion Impairs Whole Kidney Blood Flow Autoregulation in Male and Female Rats. Submitted to the Experimental Biology 2020 meeting January 29, 2020.
176. Dunaway, Luke S., Anthony K. Cook, Edward W. Inscho, and Jennifer S. Pollock. High Salt Disrupts Renal Microvascular Nitric Oxide Signaling via an HDAC1-dependent Mechanism and a Circulating Factor. Submitted to the Nitric Oxide Society February 5, 2020.
177. Guan, Zhengrong, Wenguang Feng, Colton E. Remedies, Bailey A. McEachen, Anthony K. Cook, Edward W. Inscho. Endothelial Function in Rat Juxtamedullary Afferent Arterioles after Renal Ischemia-Reperfusion Injury. Submitted to the American Heart Association Council on Hypertension meeting June 11, 2020.
178. Dunaway, Luke S., Anthony K. Cook, Edward W. Inscho, and Jennifer S. Pollock. High Salt Induces an Endothelial HDAC1-stimulating Circulating Factor Leading to Disrupted Renal Microvascular Nitric Oxide Signaling. Submitted to the American Heart Association Council on Hypertension meeting June 11, 2020.
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