Chapter 9. Cellular Respiration STAGE 1: Glycolysis
[Pages:18]Chapter 9. Cellular Respiration STAGE 1: Glycolysis
AP Biology
2005-2006
What's the point?
ATP
The Point is to Make ATP!
AP Biology
2005-2006
Glycolysis Breaking down glucose
"glyco ? lysis" (splitting sugar)
glucose pyruvate
6C
2x 3C
most ancient form of energy capture
starting point for all cellular respiration
inefficient
generate only 2 ATP for every 1 glucose
in cytosol
why does that make evolutionary sense?
AP Biology
2005-2006
Evolutionary perspective
Life on Earth first evolved without
free oxygen (O2) in atmosphere
energy had to be captured from organic molecules in absence of O2
Organisms that evolved glycolysis
are ancestors of all modern life
all organisms still utilize glycolysis
You mean, I'm related to them?!
AP Biology
2005-2006
Overview
10 reactions
glucose C-C-C-C-C-C
2 ATPaecnteivrgaytion
convert
2 ADP
6C glucose to two 3C pyruvate
fructose-6P
produce 2 ATP P-C-C-C-C-C-C-P
& 2 NADH
DHAP
PGAL
P-C-C-C C-C-C-P 2 NAD+
2 NADH
4 ADP
pyruvate 4 ATP
AP Biology
C-C-C
2005-2006
Glycolysis summary
endergonic invest some ATP
exergonic harvest a little more ATP & a little NADH
AP Biology
2005-2006
1st half of glycolysis (5 reactions) Glucose
"priming"
get glucose ready to split
phosphorylate glucose
rearrangement
split destabilized glucose
PGAL
Pay attention to AP Biology the enzymes!
2005-2006
2nd half of glycolysis (5 reactions) Oxidation
G3P donates H NAD NADH
ATP generation
G3P pyruvate donates P ADP ATP
Payola!
Finally some
AP Biology
ATP!
2005-2006
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