AP Biology: Cellular Respiration Review
AP Biology: Cellular Respiration Review
Name __________________________________________
1. Write the equation for cellular respiration.
C6H12O6 + 6O2 ----- 6CO2 + 6H2O + energy
2. Fill in the appropriate terms in the equation.
Xe- + Y → X + Ye-
X is the reducing agent; it becomes __oxidized_
Y is the _Oxidizing agent; it becomes _reduced_
3. In cellular respiration: the conversion of glucose and oxygen to carbon dioxide and water.
a. Which molecule is reduced?
O2
b. Which molecule is oxidized?
C6H12O6
c. What happens to the energy that is released in this redox reaction?
Stored in the carriers, ATP production, heat
4. NAD+ is called an _electron carrier_.
4a. Its reduced form is _NADH__.
5. Fill in the tally of maximum ATP yield from the oxidation of one molecule of glucose to six molecules of carbon dioxide.
Process # ATP
Initial phosphorylation of glucose _-2_
Substrate level phosphorylation:
In Glycolysis __+4_
In _citric acid ___ __+2_
Oxidative Phosphorylation _+32-34_
Maximum Total _~38
6. How much more ATP can be generated by respiration than by fermentation? Explain why.
36 more ATP – fermentation only keeps glycolysis going (2 ATP)
7. Complete the Table below:
|Process |Main Function |Inputs |Outputs |
|Glycolysis |Split glucose |Glucose |Pyruvate |
| | |2 NAD |NADH |
| | |2ATP |ATP |
|Pyruvate to acetyl CoA |Oxidation |Pyruvate |Acetyl CoA |
| | |Coenzyme A |NADH |
| | | |CO2 |
|Citric acid cycle |Oxidation |Acetyl CoA |CO2 |
| | |NAD |ATP |
| | |FAD |NADH |
| | | |FADH2 |
|Oxidative |Production of ATP|NADH |NAD |
|phosphorylation | |FADH2 |FAD |
| | |O2 |H2O |
| | |ADP + P |ATP |
|Fermentation |Recycle NAD |NADH |NAD |
| | |Pyruvate |Ethanol or lactic|
| | | |acid |
8. A substrate that is phosphorylated
a. has lost a phosphate group
b. has been formed by the reaction
ADP + P → ATP
c. has an increased reactivity
d. has been oxidized
e. will pass its electrons to the electron
transport chain
9. Which of the following is not true of oxidative phosphorylation?
a. It produces approximately three ATP for every NADH that is oxidized.
b. It involves the redox reactions of the electron transport chain.
c. It involves an ATP synthase located in the mitochondrial membrane.
d. It uses oxygen as the initial electron acceptor.
e. It is an example of Chemiosmosis.
10. Substrate level phosphorylation
a. involves the shifting of a phosphate group from ATP to a substrate.
b. can use NADH or FADH2.
c. takes place in the cytosol.
d. accounts for 10% of the ATP formed by fermentation.
e. is the energy source for facultative anaerobes under anaerobic conditions.
11. The major reason that gycolysis is not as energy-productive as respiration is that
a. NAD+ is regenerated by alcohol or lactate production, without the high-energy electrons passing through the electron transport chain.
b. it is the pathway common to fermentation and respiration.
c. it does not take place in a specialized membrane bound organelle.
d. pyruvate is more reduced than CO2; it still contains much of the energy from glucose.
e. substrate-level phosphorylation is not as energy efficient as oxidative phosphorylation.
12. The net products of Glycolysis are
a. 2 ATP, 2 CO2, 2 ethanol
b. 2 ATP, 2 NAD+, 2 acetate
c. 2 ATP, 2NADH, 2 pyruvate, 2 H2O
d. 38 ATP, 6 CO2, 6 H2O
e. 4 ATP, 2 FADH2, 2 pyruvate
13. When pyruvate is converted to acetyl CoA
a. CO2 and pyruvate are released
b. a multienzyme complex removes a carboxyl group, transfers electrons to NAD+ and attaches a coenzyme
c. one turnoff the citric acid cycle is completed.
d. NAD+ is regenerated is that glycolysis can continue to produce ATP by substrate level phosphorylation
e. phosphofructokinase is activated and glycolysis continues
14. Which of the following produces the most ATP per gram?
a. glucose, because it is the starting place for glycolysis
b. glycogen and starch, because they are polymers of glucose
c. fats, because they are highly reduced compounds
d. proteins, because of the energy stored in their tertiary structure
15. Fats and proteins can be used as fuel in the cell because they
a. can be converted to glucose by enzymes
b. can be converted to intermediates of glycolysis or the citric acid cycle
c. can pass through the mitochondrial membrane to enter the citric acid cycle
d. contain stable phosphate groups
e. contain more energy than glucose
16. Which of the following is not true of the enzyme phosphofructokinase? It is
a. an allosteric enzyme
b. inhibited by citrate
c. the pacemaker of glycolysis and respiration\
d. inhibited by ADP
e. an early enzyme in the glycolytic pathway
17. Cyanide is a poison that blocks the passage of electrons along the electron transport chain. Which of the following is a metabolic effect of this poison?
a. The pH of the intermembrane space is much lower than normal.
b. Electrons are passed directly to oxygen, causing cells to explode.
c. Alcohol would build up in the cells.
d. NADH supplies would be exhausted, and ATP synthesis would cease.
e. No proton gradient would be produced, and ATP synthesis would stop.
18. Why is glycolysis considered one of the first metabolic pathways to have evolved?
a. It relies on fermentation, which is characteristic of the archea and bacteria.
b. It is found only in prokaryotes, whereas eukaryotes use their mitochondria to produce ATP.
c. It produces much less ATP than does the electron transport.
d. It relies totally on enzymes that are produced by free ribosomes, and bacteria have free ribosomes and not bound ribosomes.
e. It is nearly universal, is located in the cytosol and does not involve O2
19. The metabolic function of fermentation is to
a. oxidize NADH to NAD+ so that glycolysis can continue in the absence of oxygen.
b. reduce NADH so that more ATP can be produced by the electron transport chain.
c. produce lactate during aerobic exercise.
d. oxidize pyruvate in order to release more energy.
e. make beer.
20. What is the role of oxygen in cellular respiration?
a. It is reduced in glycolysis as glucose is oxidized.
b. It provides electrons to the electron transport chain.
c. It provides the activation energy needed for oxidation to occur.
d. It is the final electron acceptor for the electron transport chain.
e. It combines with the carbon removed during the citric acid cycle to form CO2.
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