Physiologic differences between infants, children and adults

Infant skull much less rigid than adult; can estimate ICP by palpation of fontanelle. Autoregulation of CBF impaired in the sick newborn. Intraventricular hemorrhage (IVF) common in pre-term infants. Predisposing factors are hypoxia, hypercarbia, hypernatremia, fluctuation in arterial/venous pressure, low Hct, rapid administration of hypertonic ... ................
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