BE209 Principles of Molecular Cell Biology and Biotechnology



BE209 Principles of Molecular Cell Biology and BiotechnologyFall 2020 Course InformationLectures Tu/Th 10-12pm, Room EPC204The goal of this course is to introduce the basic principles of molecular and cellular biology, with more focus on modern biotechnological applications. Textbook readings will be used to develop a foundation of basic facts and concepts. Topics include:Introduction to cellsChemical components of cells and basic energeticsProteins and catalysisDNA, chromosomes and genomesDNA replication, repair and recombinationMolecular Cloning and Genome EngineeringDNA sequencingHow cells read the genome, from DNA to proteinControl of gene expressionMicroarrays and RNAiEnergy from foodEnergy conversion: mitochondria and chloroplastsMembrane structure and cross-transportIntracellular organelle transportMid-term preview and problem set reviewMechanisms of cell communicationCytoskeleton, cell junctions, cell adhesion and the extracellular maxtrixCell cycle and apoptosisCell division and meiosisStem cell and nuclear transfer (cloning)CancerImmunology and ImmunotherapyCourse StaffLecturers: Wilson Wong, CILSE 403B, wilwong@bu.edu, 617-358-6958 Lab Instructor: Xin Brown, xinq@bu.eduCourse TA:Ting-Ya Chang, tingyac@bu.eduLab TA:Ting-Ya Chang, cfthomas@bu.eduWebsiteThe course website is being hosted via BU Blackboard at . You should be able to access the site if you are registered for the course. If you have any problem with this, please email us.Office hourProfessor Wilson Wong: TBD: zoomTing-Ya (Sophia) Chang: TBD: RoomGradingYour grade in this course will be based on the following:Problem Sets (10%)Midterm Exams and Final (60%)Lab (30%)TextbooksThe primary textbook for the course will be (ECB) Essential Cell Biology, by Alberts et al., Garland Science (we suggest the latest, 4th edition)This is nice and easy to read textbook that contains have more information than what will be covered in class. We encourage the students to read the book correspond to the lecture topics. Exam questions may be derived from the textbook reading even though it may not be covered in class.Problem SetsThere will be three problem sets for this course. Problem sets are designed to reinforce the integration of key concepts and facts, promote critical reasoning about experimental methods.Midterm Exams and FinalsThere will be two midterm exams, as noted on the class schedule. The final will be a comprehensive exam that covers the entire course, but will have a stronger focus on the materials after midterm two. ................
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