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Tuesday, June 16, 2015

The JAMA Report Video and Multimedia Assets are available at

Please call: JAMA Media Relations with any questions: (312) 464-5262

“Higher Quality Screening Colonoscopies Associated with Lower Risk of Colon Cancer Death without Increased Costs”

TEASE RUNS: 04 (patient having colonoscopy)

The importance of having a high-quality screening colonoscopy…that’s next.

JAMA 3985

TRT: 2:02

EMBARGO: 11a.m. (ET) Tuesday, June 16, 2015

INTRO: By identifying and removing small cancers and pre-cancerous polyps called adenomas, screening colonoscopies can decrease the risk of death from colon cancer. But the quality of the actual colonoscopy is important. One way to assess quality is to measure how often these procedures identify pre-cancerous polyps, known as the adenoma detection rate. A new study examined how different adenoma detection rates might affect colon cancer outcomes and cost. Catherine Dolf explains in this week’s JAMA Report.

| VIDEO | AUDIO |

|B-ROLL |KAREN VACCARO JUST HAD HER FIRST SCREENING COLONOSCOPY THREE WEEKS AGO. SHE HAD PUT OFF THIS TEST |

|Karen walking outside |FOR SEVERAL YEARS BECAUSE OF CONCERNS ABOUT THE PREP AND ALSO FEAR ABOUT WHAT THE DOCTOR MIGHT |

| |FIND. |

| | |

|SOT/FULL |“I knew that I wanted to have it done at a place where the quality of the work was really very |

|Karen Vaccaro - Colonoscopy Patient |high.” |

|Super@ :10 | |

|Runs:07 | |

|SOT/FULL |“It’s important to have a properly trained physician who is aware of their overall polyp detection |

|Michael Kochman, M.D., - University of Pennsylvania |rate. |

|Super@:17 | |

|Runs:07 | |

|B-ROLL |THIS IS KNOWN AS THE ADENOMA DETECTION RATE. AN ADENOMA IS A TYPE OF POLYP THAT IS BENIGN BUT COULD|

|Graphic: Polyp turning from benign to cancerous, doctor |GROW INTO COLON CANCER OVER TIME. THE ADENOMA DETECTION RATE CAN VARY WIDELY DEPENDING ON WHO IS |

|performing a colonoscopy |PERFORMING THE COLONOSCOPY. |

| | |

|SOT/FULL |“When you have this variation in detection rates it leads to a lot of adverse consequences.” |

|Chyke A. Doubeni, M.D., M.P.H., - University of Pennsylvania | |

|Super@:36 | |

|Runs:06 | |

|B-ROLL |DR. CHYKE (Ch-IKE) DOUBENI (Dow-Benny) FROM THE UNIVERSITY OF PENNSYLVANIA AND CO-AUTHORS USED |

|Graphic:57,588 Patients,136 Gastroenterologists, Adenoma |CLINICAL INFORMATION FROM MORE THAN 57 THOUSAND PATIENTS WHO UNDERWENT COLONOSCOPY BY 136 |

|Detection Rate, Key Clinical Outcomes, Dr. Doubeni looking at |GASTROENTEROLOGISTS FROM THE KAISER PERMANENTE SYSTEM. THE DATA, INCLUDING ADENOMA DETECTION RATE |

|computer, various shots of polyps |AND KEY CLINICAL OUTCOMES RELATED TO COLON CANCER, WERE INCORPORATED INTO A MATHEMATICAL MODEL |

| |USING A PROCESS KNOWN AS A MICROSIMULATION. THE MODEL WAS USED TO ESTIMATE REAL LIFE OUTCOMES BASED|

| |ON DIFFERENT ADENOMA DETECTION RATES, COLON CANCER RELATED DEATHS, AND COSTS OF SCREENING. |

|SOT/FULL |“With higher quality of colonoscopy the lifetime risk of colorectal cancer as well as the risk of |

|Chyke A. Doubeni, M.D., M.P.H., - University of Pennsylvania |dying from colorectal cancer was lower. If your physician had a lower detection rate patients |

|Super@1:12 |outcomes were less favorable than if you had a higher detection rate colonoscopy.” |

|Runs:16 | |

|(Video covering middle and end of bite: Dr. Doubeni at computer,| |

|colonoscopy) | |

|GXF FULL |THE STUDY APPEARS IN JAMA, JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. |

|JAMA LOGO | |

|SOT/FULL |“With higher detection or higher quality of the test your benefit from screening is even better at |

|Chyke A. Doubeni, M.D., M.P.H., - University of Pennsylvania |no additional costs.” |

|Super@1:35 | |

|Runs:08 | |

|(Video covering 1st half of bite: colonoscopy) | |

|SOT/FULL |“Colonoscopy is a national priority; to make sure that we have 80 percent of the eligible |

|Michael Kochman, M.D., - University of Pennsylvania |population in the US screened by 2018.” |

|Super@1:40 | |

|Runs:11 | |

|B-ROLL |KAREN RECEIVED GOOD NEWS. HER COLONOSCOPY WAS CLEAN, NO POLYPS. |

|Karen sitting outside | |

|SOT/FULL |“I realize that I should not have waited. I’ll go right when the ten years are up, not a problem.” |

|Karen Vaccaro - Colonoscopy Patient | |

|Super@ 1:57 | |

|Runs:05 | |

|(Video covering 1st part of bite: Karen outside) | |

|B-ROLL |CATHERINE DOLF, THE JAMA REPORT. |

|Karen on camera | |

TAG: COLORECTAL CANCER IS THE SECOND LEADING CAUSE OF CANCER DEATHS IN THE UNITED STATES.

Please see the complete study for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

TO CONTACT: Dr. Chyke Doubeni call: Greg Richter at: (215) 614-1937

ADDITIONAL SOUNDBITES:

QUOTE 1 Runs:14

“Colorectal screening using colonoscopy is effective in reducing the risk of colorectal cancer and dying from colorectal cancer in the long run but when quality is higher as measured by the adenoma detection rates, the benefits are even maximized.”

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