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Appendix ETable 6. Wording of conclusion ReferenceAuthors’ Conclusion Statement ReviewersDirect Use of EQ/NI TermsStrength of Evidence RatingConclusions Paired with Strength of Evidence or Internal Validity Rating of EvidenceBodri et al. 2011 ADDIN REFMGR.CITE <Refman><Cite><Author>Bodri</Author><Year>2011</Year><RecNum>567679</RecNum><IDText>Gonadotropin-releasing hormone agonists versus antagonists for controlled ovarian hyperstimulation in oocyte donors: a systematic review and meta-analysis</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567679</Ref_ID><Title_Primary>Gonadotropin-releasing hormone agonists versus antagonists for controlled ovarian hyperstimulation in oocyte donors: a systematic review and meta-analysis</Title_Primary><Authors_Primary>Bodri,D.</Authors_Primary><Authors_Primary>Sunkara,S.K.</Authors_Primary><Authors_Primary>Coomarasamy,A.</Authors_Primary><Date_Primary>2011/1</Date_Primary><Keywords>Female</Keywords><Keywords>Fertilization in Vitro</Keywords><Keywords>Gonadotropin-Releasing Hormone</Keywords><Keywords>*agonists</Keywords><Keywords>*antagonists &amp; inhibitors</Keywords><Keywords>Humans</Keywords><Keywords>Oocyte Donation</Keywords><Keywords>*methods</Keywords><Keywords>Ovulation Induction</Keywords><Keywords>*methods</Keywords><Keywords>Pregnancy</Keywords><Keywords>*Pregnancy Rate</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Reprint>Not in File</Reprint><Start_Page>164</Start_Page><End_Page>169</End_Page><Periodical>Fertil Steril</Periodical><Volume>95</Volume><Issue>1</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20684954</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Clinica Eugin, Departament de Pediatria, Obstetricia i Ginecologia i Medicina Preventiva, Universitat Autonoma de Barcelona, Barcelona, Spain. bodridaniel@</Address><ZZ_JournalStdAbbrev><f name="System">Fertil Steril</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>19“Currently available evidence suggests a similar effectiveness of GnRH antagonists and agonists in the context of oocyte donation. Owing to its increased safety potential, the GnRH antagonist protocol combined with GnRH agonist triggering could be advocated as the treatment of first choice for oocyte donors.”YesNot reportedNot reportedGroeneveld et al. 2011 ADDIN REFMGR.CITE <Refman><Cite><Author>Groeneveld</Author><Year>2011</Year><RecNum>567914</RecNum><IDText>Update on the comparative safety of colloids: a systematic review of clinical studies</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567914</Ref_ID><Title_Primary>Update on the comparative safety of colloids: a systematic review of clinical studies</Title_Primary><Authors_Primary>Groeneveld,A.B.</Authors_Primary><Authors_Primary>Navickis,R.J.</Authors_Primary><Authors_Primary>Wilkes,M.M.</Authors_Primary><Date_Primary>2011/3</Date_Primary><Keywords>Colloids</Keywords><Keywords>Dextrans</Keywords><Keywords>*administration &amp; dosage</Keywords><Keywords>adverse effects</Keywords><Keywords>Fluid Therapy</Keywords><Keywords>*methods</Keywords><Keywords>Gelatin</Keywords><Keywords>*administration &amp; dosage</Keywords><Keywords>adverse effects</Keywords><Keywords>Hetastarch</Keywords><Keywords>*administration &amp; dosage</Keywords><Keywords>adverse effects</Keywords><Keywords>Humans</Keywords><Keywords>Intensive Care Units</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Resusc</Keywords><Reprint>Not in File</Reprint><Start_Page>470</Start_Page><End_Page>483</End_Page><Periodical>Ann Surg</Periodical><Volume>253</Volume><Issue>3</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>21217516</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Intensive Care, Vrije Universiteit Medical Center, Amsterdam, The Netherlands</Address><ZZ_JournalStdAbbrev><f name="System">Ann Surg</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>11“Albumin displayed a more favorable safety profile than HES. Available evidence does not support the existence of consistent safety differences between HES solutions.”NoNot reportedNot reportedHockenhullet al. 2011 ADDIN REFMGR.CITE <Refman><Cite><Author>Greenhalgh</Author><Year>2010</Year><RecNum>567432</RecNum><IDText>Drug-eluting stents versus bare metal stents for angina or acute coronary syndromes</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567432</Ref_ID><Title_Primary>Drug-eluting stents versus bare metal stents for angina or acute coronary syndromes</Title_Primary><Authors_Primary>Greenhalgh,J.</Authors_Primary><Authors_Primary>Hockenhull,J.</Authors_Primary><Authors_Primary>Rao,N.</Authors_Primary><Authors_Primary>Dundar,Y.</Authors_Primary><Authors_Primary>Dickson,R.C.</Authors_Primary><Authors_Primary>Bagust,A.</Authors_Primary><Date_Primary>2010</Date_Primary><Keywords>Acute Coronary Syndrome</Keywords><Keywords>*therapy</Keywords><Keywords>Adult</Keywords><Keywords>Angioplasty,Balloon,Coronary</Keywords><Keywords>Coronary Restenosis</Keywords><Keywords>prevention &amp; control</Keywords><Keywords>*Drug-Eluting Stents</Keywords><Keywords>Humans</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Stents</Keywords><Reprint>Not in File</Reprint><Start_Page>CD004587</Start_Page><Periodical>Cochrane Database Syst Rev</Periodical><Issue>5</Issue><User_Def_2>MEDLINE - Ovid 5/23/2011, MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20464732</ISSN_ISBN><Availability>NGC0010 , Sharepoint , SP0106 , NGC0001 , SP0106_May5 , SP0106_Methods2</Availability><Address>Liverpool Reviews and Implementation Group, University of Liverpool, Sherrington Building, Ashton Street, Liverpool, UK, L69 3GE</Address><ZZ_JournalStdAbbrev><f name="System">Cochrane Database Syst Rev</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>20“The [drug eluting stents] in this analysis performed no better than [bare metal stents] on the outcomes of mortality, [acute myocardial infarction], or thrombosis. Drug eluting stents releasing sirolimus, paclitaxel, dexamethasone and zotarolimus reduce composite cardiac events. However, this reduction is due largely to reductions in repeat revascularization rates as there is no evidence of a significant effect on rates of death, myocardial infarction, or thrombosis. The increased cost of drug eluting stents and lack of evidence of their cost-effectiveness means that various health fund agencies are having to limit or regulate their used in relation to price premium.”NoNot reportedNot reportedSeitz et al. 2011 ADDIN REFMGR.CITE <Refman><Cite><Author>Seitz</Author><Year>2011</Year><RecNum>567889</RecNum><IDText>Antidepressants for agitation and psychosis in dementia</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567889</Ref_ID><Title_Primary>Antidepressants for agitation and psychosis in dementia</Title_Primary><Authors_Primary>Seitz,D.P.</Authors_Primary><Authors_Primary>Adunuri,N.</Authors_Primary><Authors_Primary>Gill,S.S.</Authors_Primary><Authors_Primary>Gruneir,A.</Authors_Primary><Authors_Primary>Herrmann,N.</Authors_Primary><Authors_Primary>Rochon,P.</Authors_Primary><Date_Primary>2011</Date_Primary><Keywords>Adult</Keywords><Keywords>Antidepressive Agents</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Citalopram</Keywords><Keywords>therapeutic use</Keywords><Keywords>Dementia</Keywords><Keywords>*psychology</Keywords><Keywords>Humans</Keywords><Keywords>Psychomotor Agitation</Keywords><Keywords>*drug therapy</Keywords><Keywords>Psychotic Disorders</Keywords><Keywords>*drug therapy</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Risperidone</Keywords><Keywords>therapeutic use</Keywords><Keywords>Serotonin Uptake In</Keywords><Reprint>Not in File</Reprint><Start_Page>CD008191</Start_Page><Periodical>Cochrane Database Syst Rev</Periodical><Volume>2</Volume><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>21328305</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Psychiatry, Queen&apos;s University, 752 King Street West, Kingston, Ontario, Canada, K7L 4X3</Address><ZZ_JournalStdAbbrev><f name="System">Cochrane Database Syst Rev</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>21“Currently there are relatively few studies of antidepressants for the treatment of agitation and psychosis in dementia. The SSRIs sertraline and citalopram were associated with a reduction in symptoms of agitation when compared to placebo in two studies. Both SSRIs and Trazodone appear to be tolerated reasonably well when compared to placebo, typical antipsychotics, and atypical antipsychotics. Future studies involving more subjects are required to determine if SSRIs, trazadone, or other antidepressants are safe and effective treatments for agitation and psychosis in dementia.”NoNot reportedNot reportedBeauchamp et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Beauchamp</Author><Year>2010</Year><RecNum>567231</RecNum><IDText>Interval versus continuous training in individuals with chronic obstructive pulmonary disease--a systematic review</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567231</Ref_ID><Title_Primary>Interval versus continuous training in individuals with chronic obstructive pulmonary disease--a systematic review</Title_Primary><Authors_Primary>Beauchamp,M.K.</Authors_Primary><Authors_Primary>Nonoyama,M.</Authors_Primary><Authors_Primary>Goldstein,R.S.</Authors_Primary><Authors_Primary>Hill,K.</Authors_Primary><Authors_Primary>Dolmage,T.E.</Authors_Primary><Authors_Primary>Mathur,S.</Authors_Primary><Authors_Primary>Brooks,D.</Authors_Primary><Date_Primary>2010/2</Date_Primary><Keywords>Exercise Therapy</Keywords><Keywords>*methods</Keywords><Keywords>Exercise Tolerance</Keywords><Keywords>physiology</Keywords><Keywords>Female</Keywords><Keywords>Humans</Keywords><Keywords>Male</Keywords><Keywords>Oxygen Consumption</Keywords><Keywords>physiology</Keywords><Keywords>Pulmonary Disease,Chronic Obstructive</Keywords><Keywords>physiopathology</Keywords><Keywords>*rehabilitation</Keywords><Keywords>Quality of Life</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Reprint>Not in File</Reprint><Start_Page>157</Start_Page><End_Page>164</End_Page><Periodical>Thorax</Periodical><Volume>65</Volume><Issue>2</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>19996334</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Physical Therapy, University of Toronto, 500 University Avenue, Toronto, Ontario, Canada</Address><ZZ_JournalStdAbbrev><f name="System">Thorax</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>5“Interval and continuous training modalities did not differ in their effect on measures of exercise capacity or HRQoL. Interval training may be considered as an alternative to continuous training in patients with varying degrees of COPD severity.”NoNot reportedNot reportedDavis et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Davis</Author><Year>2010</Year><RecNum>567128</RecNum><IDText>Arthroscopic versus open acromioplasty: a meta-analysis</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567128</Ref_ID><Title_Primary>Arthroscopic versus open acromioplasty: a meta-analysis</Title_Primary><Authors_Primary>Davis,A.D.</Authors_Primary><Authors_Primary>Kakar,S.</Authors_Primary><Authors_Primary>Moros,C.</Authors_Primary><Authors_Primary>Kaye,E.K.</Authors_Primary><Authors_Primary>Schepsis,A.A.</Authors_Primary><Authors_Primary>Voloshin,I.</Authors_Primary><Date_Primary>2010/3</Date_Primary><Keywords>Acromion</Keywords><Keywords>*surgery</Keywords><Keywords>Arthroscopy</Keywords><Keywords>*methods</Keywords><Keywords>Clinical Trials as Topic</Keywords><Keywords>Humans</Keywords><Keywords>Joint Instability</Keywords><Keywords>surgery</Keywords><Keywords>Length of Stay</Keywords><Keywords>Pain,Postoperative</Keywords><Keywords>surgery</Keywords><Keywords>Range of Motion,Articular</Keywords><Keywords>Recovery of Function</Keywords><Keywords>Rotator Cuff</Keywords><Keywords>surgery</Keywords><Keywords>Shoulder Impingement Syndrome</Keywords><Keywords>*surgery</Keywords><Keywords>Shoulde</Keywords><Reprint>Not in File</Reprint><Start_Page>613</Start_Page><End_Page>618</End_Page><Periodical>Am J Sports Med</Periodical><Volume>38</Volume><Issue>3</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 6/1/2011 for SP0106</User_Def_3><ISSN_ISBN>19188562</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Orthopaedic Surgery, Boston University Medical Center, Boston, MA, USA</Address><ZZ_JournalStdAbbrev><f name="System">Am J Sports Med</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>22“Arthroscopic and open acromioplasty have equivalent ultimate clinical outcomes, operative times, and low complication rates. However, arthroscopic acromioplasty results in faster return to work and fewer hospital inpatient days compared with the arthroscopic technique.”YesNot reportedNot reportedDibra et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Dibra</Author><Year>2010</Year><RecNum>567348</RecNum><IDText>Drug-eluting stents in acute myocardial infarction: updated meta-analysis of randomized trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567348</Ref_ID><Title_Primary>Drug-eluting stents in acute myocardial infarction: updated meta-analysis of randomized trials</Title_Primary><Authors_Primary>Dibra,A.</Authors_Primary><Authors_Primary>Tiroch,K.</Authors_Primary><Authors_Primary>Schulz,S.</Authors_Primary><Authors_Primary>Kelbaek,H.</Authors_Primary><Authors_Primary>Spaulding,C.</Authors_Primary><Authors_Primary>Laarman,G.J.</Authors_Primary><Authors_Primary>Valgimigli,M.</Authors_Primary><Authors_Primary>Di,Lorenzo E.</Authors_Primary><Authors_Primary>Kaiser,C.</Authors_Primary><Authors_Primary>Tierala,I.</Authors_Primary><Authors_Primary>Mehilli,J.</Authors_Primary><Authors_Primary>Campo,G.</Authors_Primary><Authors_Primary>Thuesen,L.</Authors_Primary><Authors_Primary>Vink,M.A.</Authors_Primary><Authors_Primary>Schalij,M.J.</Authors_Primary><Authors_Primary>Violini,R.</Authors_Primary><Authors_Primary>Schomig,A.</Authors_Primary><Authors_Primary>Kastrati,A.</Authors_Primary><Date_Primary>2010/6</Date_Primary><Keywords>*Angioplasty,Balloon,Coronary</Keywords><Keywords>Drug-Eluting Stents</Keywords><Keywords>Humans</Keywords><Keywords>Myocardial Infarction</Keywords><Keywords>*therapy</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Treatment Outcome</Keywords><Reprint>Not in File</Reprint><Start_Page>345</Start_Page><End_Page>357</End_Page><Periodical>Clin Res Cardiol</Periodical><Volume>99</Volume><Issue>6</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20221617</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Deutsches Herzzentrum, Technische Universitat, Lazarettstr. 36, 80636, Munich, Germany</Address><ZZ_JournalStdAbbrev><f name="System">Clin Res Cardiol</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>16“There was no difference in the hazard of death or recurrent myocardial infarction between patients treated with drug-eluting stents versus bare metal stents. Treatment with drug-eluting stents resulted in a significant reduction in the hazard of reintervention. The hazards of death, myocardial infarction, and stent thrombosis were not significantly different between [patient groups]. Use of drug eluting stents in patients with acute myocardial infarction is safe and markedly reduces the need for reintervention.”NoNot reportedNot reportedDong et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Dong</Author><Year>2010</Year><RecNum>567458</RecNum><IDText>Early administration of small-molecule glycoprotein IIb/IIIa inhibitors before primary percutaneous coronary intervention for ST-elevation myocardial infarction: insights from randomized clinical trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567458</Ref_ID><Title_Primary>Early administration of small-molecule glycoprotein IIb/IIIa inhibitors before primary percutaneous coronary intervention for ST-elevation myocardial infarction: insights from randomized clinical trials</Title_Primary><Authors_Primary>Dong,L.</Authors_Primary><Authors_Primary>Zhang,F.</Authors_Primary><Authors_Primary>Shu,X.</Authors_Primary><Date_Primary>2010/6</Date_Primary><Keywords>Angioplasty,Balloon,Coronary</Keywords><Keywords>*methods</Keywords><Keywords>Antibodies,Monoclonal</Keywords><Keywords>administration &amp; dosage</Keywords><Keywords>adverse effects</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Anticoagulants</Keywords><Keywords>administration &amp; dosage</Keywords><Keywords>adverse effects</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Humans</Keywords><Keywords>Immunoglobulin Fab Fragments</Keywords><Keywords>administration &amp; dosage</Keywords><Keywords>adv</Keywords><Reprint>Not in File</Reprint><Start_Page>135</Start_Page><End_Page>144</End_Page><Periodical>J Cardiovasc Pharmacol Ther</Periodical><Volume>15</Volume><Issue>2</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/31/2011 for SP0106</User_Def_3><ISSN_ISBN>20435991</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China</Address><ZZ_JournalStdAbbrev><f name="System">J Cardiovasc Pharmacol Ther</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>23“This meta-analysis shows that early administration of smGPIs is as effective as abciximab in the setting of PPCI for STEMI, without an increase in bleeding complications.”YesNot reportedNot reportedDong et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Dong</Author><Year>2010</Year><RecNum>567507</RecNum><IDText>Upstream vs deferred administration of small-molecule glycoprotein IIb/IIIa inhibitors in primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: insights from randomized clinical trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567507</Ref_ID><Title_Primary>Upstream vs deferred administration of small-molecule glycoprotein IIb/IIIa inhibitors in primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: insights from randomized clinical trials</Title_Primary><Authors_Primary>Dong,L.</Authors_Primary><Authors_Primary>Zhang,F.</Authors_Primary><Authors_Primary>Shu,X.</Authors_Primary><Date_Primary>2010/8</Date_Primary><Keywords>Angioplasty,Balloon,Coronary</Keywords><Keywords>*methods</Keywords><Keywords>Antibodies,Monoclonal</Keywords><Keywords>therapeutic use</Keywords><Keywords>Humans</Keywords><Keywords>Immunoglobulin Fab Fragments</Keywords><Keywords>therapeutic use</Keywords><Keywords>Myocardial Infarction</Keywords><Keywords>*drug therapy</Keywords><Keywords>mortality</Keywords><Keywords>Platelet Aggregation Inhibitors</Keywords><Keywords>*administration &amp; dosage</Keywords><Keywords>Platelet Glycoprotein</Keywords><Reprint>Not in File</Reprint><Start_Page>1617</Start_Page><End_Page>1624</End_Page><Periodical>Circ J</Periodical><Volume>74</Volume><Issue>8</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/25/2011 for SP0106</User_Def_3><ISSN_ISBN>20571247</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China</Address><ZZ_JournalStdAbbrev><f name="System">Circ J</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>24“In STEMI patients scheduled for primary PCI, although early smGPIs treatment improved initial epicardial patency, no beneficial effect on post-procedural angiographic or 30-day clinical outcome was found. Thus, the current available data do not support the routine utilization of upstream smGPIs in STEMI patients treated with primary PCI.”NoNot reportedNot reportedDubicka et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Dubicka</Author><Year>2010</Year><RecNum>567970</RecNum><IDText>Combined treatment with cognitive-behavioural therapy in adolescent depression: meta-analysis</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567970</Ref_ID><Title_Primary>Combined treatment with cognitive-behavioural therapy in adolescent depression: meta-analysis</Title_Primary><Authors_Primary>Dubicka,B.</Authors_Primary><Authors_Primary>Elvins,R.</Authors_Primary><Authors_Primary>Roberts,C.</Authors_Primary><Authors_Primary>Chick,G.</Authors_Primary><Authors_Primary>Wilkinson,P.</Authors_Primary><Authors_Primary>Goodyer,I.M.</Authors_Primary><Date_Primary>2010/12</Date_Primary><Keywords>Adolescent</Keywords><Keywords>Child</Keywords><Keywords>*Cognitive Therapy</Keywords><Keywords>Combined Modality Therapy</Keywords><Keywords>methods</Keywords><Keywords>Depressive Disorder</Keywords><Keywords>*therapy</Keywords><Keywords>Female</Keywords><Keywords>Humans</Keywords><Keywords>Male</Keywords><Keywords>Practice Guidelines as Topic</Keywords><Keywords>Psychiatric Status Rating Scales</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Serotonin Uptake Inhibitors</Keywords><Keywords>*therapeu</Keywords><Reprint>Not in File</Reprint><Start_Page>433</Start_Page><End_Page>440</End_Page><Periodical>Br J Psychiatry</Periodical><Volume>197</Volume><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/31/2011 for SP0106</User_Def_3><ISSN_ISBN>21119148</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Lancashire Care Foundation Trust and Psychiatry Research Group, School of Community Based Medicine, University of Manchester, UK. Bernadka.Dubicka@manchester.ac.uk</Address><ZZ_JournalStdAbbrev><f name="System">Br J Psychiatry</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>18“There was no evidence of a statistically significant benefit of combined treatment over antidepressants for depressive symptoms, suicidality and global improvement after acute treatment or follow-up. There was a statistically significant advantage of combined treatment for impairment in the short-term. Adding CBT to antidepressants confers limited advantage for the treatment of an episode of depression in adolescents.”NoNot reported Not reportedFuentes et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Fuentes</Author><Year>2010</Year><RecNum>567702</RecNum><IDText>Effectiveness of interferential current therapy in the management of musculoskeletal pain: a systematic review and meta-analysis</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567702</Ref_ID><Title_Primary>Effectiveness of interferential current therapy in the management of musculoskeletal pain: a systematic review and meta-analysis</Title_Primary><Authors_Primary>Fuentes,J.P.</Authors_Primary><Authors_Primary>Armijo,Olivo S.</Authors_Primary><Authors_Primary>Magee,D.J.</Authors_Primary><Authors_Primary>Gross,D.P.</Authors_Primary><Date_Primary>2010/9</Date_Primary><Keywords>Chi-Square Distribution</Keywords><Keywords>Electric Stimulation Therapy</Keywords><Keywords>*methods</Keywords><Keywords>Humans</Keywords><Keywords>Musculoskeletal Diseases</Keywords><Keywords>*therapy</Keywords><Keywords>Pain</Keywords><Keywords>*therapy</Keywords><Keywords>Pain Measurement</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Reprint>Not in File</Reprint><Start_Page>1219</Start_Page><End_Page>1238</End_Page><Periodical>Phys Ther</Periodical><Volume>90</Volume><Issue>9</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20651012</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>University of Alberta, Edmonton, Alberta, Canada. jorgef@ualberta.ca</Address><ZZ_JournalStdAbbrev><f name="System">Phys Ther</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>25“IFC as a supplement to another intervention seems to be more effective for reducing pain than a control treatment at discharge and more effective than a placebo treatment at the 3-month follow-up. However, it is unknown whether the analgesic effect of IFC is superior to that of the concomitant interventions. IFC alone was not significantly better than placebo or other therapy at discharge or follow-up. Results may be considered with caution due to the low number of studies that used IFC alone. In addition, the heterogeneity across studies and methodological limitations prevents conclusive statements regarding analgesic efficacy.”YesNot reportedNot reportedHong et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Wu</Author><Year>2010</Year><RecNum>567798</RecNum><IDText>Intensive glycemic control and macrovascular events in type 2 diabetes mellitus: a meta-analysis of randomized controlled trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567798</Ref_ID><Title_Primary>Intensive glycemic control and macrovascular events in type 2 diabetes mellitus: a meta-analysis of randomized controlled trials</Title_Primary><Authors_Primary>Wu,H.</Authors_Primary><Authors_Primary>Xu,M.J.</Authors_Primary><Authors_Primary>Zou,D.J.</Authors_Primary><Authors_Primary>Han,Q.J.</Authors_Primary><Authors_Primary>Hu,X.</Authors_Primary><Date_Primary>2010/10</Date_Primary><Keywords>Blood Glucose</Keywords><Keywords>*analysis</Keywords><Keywords>Diabetes Mellitus,Type 2</Keywords><Keywords>blood</Keywords><Keywords>complications</Keywords><Keywords>*drug therapy</Keywords><Keywords>mortality</Keywords><Keywords>Diabetic Angiopathies</Keywords><Keywords>*prevention &amp; control</Keywords><Keywords>Hemoglobin A,Glycosylated</Keywords><Keywords>analysis</Keywords><Keywords>Humans</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Reprint>Not in File</Reprint><Start_Page>2908</Start_Page><End_Page>2913</End_Page><Periodical>Chin Med J (Engl)</Periodical><Volume>123</Volume><Issue>20</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/23/2011 for SP0106</User_Def_3><ISSN_ISBN>21034605</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Endocrinology, Changhai Hospital, Second Military Medical University, Shanghai, China</Address><ZZ_JournalStdAbbrev><f name="System">Chin Med J (Engl)</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>26“Control of glycemia to normal (or near normal levels) in type II diabetes appears to be effective in reducing the incidence of major macrovascular events, but there were no significant differences of either the mortality from any cause or from cardiovascular death between the two glycemia-control strategies.”NoNot reportedNot reportedHughes et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Hughes</Author><Year>2010</Year><RecNum>567530</RecNum><IDText>Intravenous immunoglobulin for Guillain-Barre syndrome</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567530</Ref_ID><Title_Primary>Intravenous immunoglobulin for Guillain-Barre syndrome</Title_Primary><Authors_Primary>Hughes,R.A.</Authors_Primary><Authors_Primary>Swan,A.V.</Authors_Primary><Authors_Primary>van Doorn,P.A.</Authors_Primary><Date_Primary>2010</Date_Primary><Keywords>Adult</Keywords><Keywords>Child</Keywords><Keywords>Guillain-Barre Syndrome</Keywords><Keywords>*therapy</Keywords><Keywords>Humans</Keywords><Keywords>Immunoglobulins,Intravenous</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Outcome Assessment (Health Care)</Keywords><Keywords>Plasma Exchange</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Reprint>Not in File</Reprint><Start_Page>CD002063</Start_Page><Periodical>Cochrane Database Syst Rev</Periodical><Issue>6</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/23/2011 for SP0106</User_Def_3><ISSN_ISBN>20556755</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>MRC Centre for Neuromuscular Disease, National Hospital for Neurology and Neurosurgery, PO Box 114, Queen Square, London, UK, WC1N 3BG</Address><ZZ_JournalStdAbbrev><f name="System">Cochrane Database Syst Rev</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>27“Intravenous immunoglobulin started within two weeks from onset hastens recovery as much as plasma exchange. Adverse events were not significantly more frequent with either treatment but intravenous immunoglobulin is significantly much more likely to be completed than plasma exchange.”NoNot reportedAuthors indicate that conclusions are based on moderate quality evidence.Kalil et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Kalil</Author><Year>2010</Year><RecNum>567714</RecNum><IDText>Linezolid versus vancomycin or teicoplanin for nosocomial pneumonia: a systematic review and meta-analysis</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567714</Ref_ID><Title_Primary>Linezolid versus vancomycin or teicoplanin for nosocomial pneumonia: a systematic review and meta-analysis</Title_Primary><Authors_Primary>Kalil,A.C.</Authors_Primary><Authors_Primary>Murthy,M.H.</Authors_Primary><Authors_Primary>Hermsen,E.D.</Authors_Primary><Authors_Primary>Neto,F.K.</Authors_Primary><Authors_Primary>Sun,J.</Authors_Primary><Authors_Primary>Rupp,M.E.</Authors_Primary><Date_Primary>2010/9</Date_Primary><Keywords>Acetamides</Keywords><Keywords>adverse effects</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Anti-Bacterial Agents</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Cross Infection</Keywords><Keywords>*drug therapy</Keywords><Keywords>microbiology</Keywords><Keywords>Education,Medical,Continuing</Keywords><Keywords>Humans</Keywords><Keywords>Oxazolidinones</Keywords><Keywords>adverse effects</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Pneumonia,Bacterial</Keywords><Keywords>*drug therapy</Keywords><Keywords>microbio</Keywords><Reprint>Not in File</Reprint><Start_Page>1802</Start_Page><End_Page>1808</End_Page><Periodical>Crit Care Med</Periodical><Volume>38</Volume><Issue>9</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/23/2011 for SP0106</User_Def_3><ISSN_ISBN>20639754</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>University of Nebraska Medical Center, Omaha, NE, USA. akalil@unmc.edu</Address><ZZ_JournalStdAbbrev><f name="System">Crit Care Med</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>2“Our study does not demonstrate clinical superiority of linezolid vs. glycopeptides for the treatment of nosocomial pneumonia despite statistical power of 95%. Linezolid shows a two-fold increase in the risk of thrombocytopenia and gastrointestinal events. Vancomycin and teicoplanin are not associated with more renal dysfunction than linezolid.”NoNot reportedNot reportedKesselheim et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Kesselheim</Author><Year>2010</Year><RecNum>567314</RecNum><IDText>Seizure outcomes following the use of generic versus brand-name antiepileptic drugs: a systematic review and meta-analysis</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567314</Ref_ID><Title_Primary>Seizure outcomes following the use of generic versus brand-name antiepileptic drugs: a systematic review and meta-analysis</Title_Primary><Authors_Primary>Kesselheim,A.S.</Authors_Primary><Authors_Primary>Stedman,M.R.</Authors_Primary><Authors_Primary>Bubrick,E.J.</Authors_Primary><Authors_Primary>Gagne,J.J.</Authors_Primary><Authors_Primary>Misono,A.S.</Authors_Primary><Authors_Primary>Lee,J.L.</Authors_Primary><Authors_Primary>Brookhart,M.A.</Authors_Primary><Authors_Primary>Avorn,J.</Authors_Primary><Authors_Primary>Shrank,W.H.</Authors_Primary><Date_Primary>2010/3/26</Date_Primary><Keywords>Anticonvulsants</Keywords><Keywords>adverse effects</Keywords><Keywords>pharmacokinetics</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Drugs,Generic</Keywords><Keywords>adverse effects</Keywords><Keywords>pharmacokinetics</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Evidence-Based Medicine</Keywords><Keywords>Humans</Keywords><Keywords>Odds Ratio</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Risk Assessment</Keywords><Keywords>Seizures</Keywords><Keywords>*prevention &amp; contr</Keywords><Reprint>Not in File</Reprint><Start_Page>605</Start_Page><End_Page>621</End_Page><Periodical>Drugs</Periodical><Volume>70</Volume><Issue>5</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20329806</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women&apos;s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA. akesselheim@</Address><ZZ_JournalStdAbbrev><f name="System">Drugs</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>3“Although most RCTs were short-term evaluations, the available evidence does not suggest an association between loss of seizure control and generic substitution of at least three types of [antiepileptic drugs] AEDs. The observational study may be explained by factors such as undue concern from patients of physicians about the effectiveness of generic AEDs after a recent switch.”NoNot reported Not reportedKrenke et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Krenke</Author><Year>2010</Year><RecNum>567441</RecNum><IDText>Local treatment of empyema in children: a systematic review of randomized controlled trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567441</Ref_ID><Title_Primary>Local treatment of empyema in children: a systematic review of randomized controlled trials</Title_Primary><Authors_Primary>Krenke,K.</Authors_Primary><Authors_Primary>Peradzynska,J.</Authors_Primary><Authors_Primary>Lange,J.</Authors_Primary><Authors_Primary>Ruszczynski,M.</Authors_Primary><Authors_Primary>Kulus,M.</Authors_Primary><Authors_Primary>Szajewska,H.</Authors_Primary><Date_Primary>2010/10</Date_Primary><Keywords>Child</Keywords><Keywords>Empyema,Pleural</Keywords><Keywords>*drug therapy</Keywords><Keywords>surgery</Keywords><Keywords>Fibrinolytic Agents</Keywords><Keywords>*administration &amp; dosage</Keywords><Keywords>Humans</Keywords><Keywords>Instillation,Drug</Keywords><Keywords>Length of Stay</Keywords><Keywords>Pleural Effusion</Keywords><Keywords>*drug therapy</Keywords><Keywords>surgery</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Thoracic Surgery,Video-Assisted</Keywords><Keywords>Treatment Outc</Keywords><Reprint>Not in File</Reprint><Start_Page>1449</Start_Page><End_Page>1453</End_Page><Periodical>Acta Paediatr</Periodical><Volume>99</Volume><Issue>10</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20456264</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Paediatric Pneumonology and Allergy, The Medical University of Warsaw, Poland. kkrenke@amwaw.edu.pl</Address><ZZ_JournalStdAbbrev><f name="System">Acta Paediatr</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>17“There is no evidence that [video assisted thoracoscopic surgery] VATs is more effective than fibrinolytic treatment.”NoNot reportedNot reportedLanitis et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Myers</Author><Year>2010</Year><RecNum>567244</RecNum><IDText>Intraspinal techniques for pain management in cancer patients: a systematic review</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567244</Ref_ID><Title_Primary>Intraspinal techniques for pain management in cancer patients: a systematic review</Title_Primary><Authors_Primary>Myers,J.</Authors_Primary><Authors_Primary>Chan,V.</Authors_Primary><Authors_Primary>Jarvis,V.</Authors_Primary><Authors_Primary>Walker-Dilks,C.</Authors_Primary><Date_Primary>2010/2</Date_Primary><Keywords>Adult</Keywords><Keywords>Aged</Keywords><Keywords>Aged,80 and over</Keywords><Keywords>Analgesics</Keywords><Keywords>*administration &amp; dosage</Keywords><Keywords>Drug Administration Schedule</Keywords><Keywords>Evidence-Based Medicine</Keywords><Keywords>Humans</Keywords><Keywords>Infusions,Subcutaneous</Keywords><Keywords>Injections,Epidural</Keywords><Keywords>Injections,Spinal</Keywords><Keywords>Middle Aged</Keywords><Keywords>Neoplasms</Keywords><Keywords>*complications</Keywords><Keywords>Pain</Keywords><Keywords>etiology</Keywords><Keywords>*therapy</Keywords><Keywords>Pain M</Keywords><Reprint>Not in File</Reprint><Start_Page>137</Start_Page><End_Page>149</End_Page><Periodical>Support Care Cancer</Periodical><Volume>18</Volume><Issue>2</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/31/2011 for SP0106</User_Def_3><ISSN_ISBN>19943068</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Palliative Care Consult Team, Odette Cancer Centre, Sunnybrook Health Sciences, Toronto, ON, Canada. jeff.myers@sunnybrook.ca</Address><ZZ_JournalStdAbbrev><f name="System">Support Care Cancer</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>28“Our results suggest that in breast cancer patients, SSM was not significantly different from NSSM in terms of rates of local reoccurrence.”NoNot reportedNot reportedLee et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Lee</Author><Year>2010</Year><RecNum>567191</RecNum><IDText>Induction and maintenance therapy for lupus nephritis: a systematic review and meta-analysis</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567191</Ref_ID><Title_Primary>Induction and maintenance therapy for lupus nephritis: a systematic review and meta-analysis</Title_Primary><Authors_Primary>Lee,Y.H.</Authors_Primary><Authors_Primary>Woo,J.H.</Authors_Primary><Authors_Primary>Choi,S.J.</Authors_Primary><Authors_Primary>Ji,J.D.</Authors_Primary><Authors_Primary>Song,G.G.</Authors_Primary><Date_Primary>2010/5</Date_Primary><Keywords>Azathioprine</Keywords><Keywords>adverse effects</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Bias (Epidemiology)</Keywords><Keywords>Cyclophosphamide</Keywords><Keywords>adverse effects</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Humans</Keywords><Keywords>Immunosuppressive Agents</Keywords><Keywords>adverse effects</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Lupus Nephritis</Keywords><Keywords>*drug therapy</Keywords><Keywords>prevention &amp; control</Keywords><Keywords>Mycophenolic Acid</Keywords><Keywords>adver</Keywords><Reprint>Not in File</Reprint><Start_Page>703</Start_Page><End_Page>710</End_Page><Periodical>Lupus</Periodical><Volume>19</Volume><Issue>6</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20064907</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Division of Rheumatology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. lyhcgh@korea.ac.kr</Address><ZZ_JournalStdAbbrev><f name="System">Lupus</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>29Findings from meta-analyses suggest that “MMF and CYC are comparable in terms of efficacy; that MMF induction therapy tends to have a more favorable safety profile; and that MMF and AZA are comparable maintenance therapies in terms of efficacy and toxicity.” Findings also suggest that low-dose IV CYC is more efficacious and safer than high-dose IV CYC for the treatment of severe lupus nephritis. YesNot reportedNot reportedLiu et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Liu</Author><Year>2010</Year><RecNum>567721</RecNum><IDText>Radiofrequency ablation in the treatment of small hepatocellular carcinoma: a meta analysis</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567721</Ref_ID><Title_Primary>Radiofrequency ablation in the treatment of small hepatocellular carcinoma: a meta analysis</Title_Primary><Authors_Primary>Liu,J.G.</Authors_Primary><Authors_Primary>Wang,Y.J.</Authors_Primary><Authors_Primary>Du,Z.</Authors_Primary><Date_Primary>2010/7/21</Date_Primary><Keywords>Bias (Epidemiology)</Keywords><Keywords>*Carcinoma,Hepatocellular</Keywords><Keywords>pathology</Keywords><Keywords>prevention &amp; control</Keywords><Keywords>therapy</Keywords><Keywords>Catheter Ablation</Keywords><Keywords>*methods</Keywords><Keywords>statistics &amp; numerical data</Keywords><Keywords>Hepatectomy</Keywords><Keywords>methods</Keywords><Keywords>statistics &amp; numerical data</Keywords><Keywords>Humans</Keywords><Keywords>*Liver Neoplasms</Keywords><Keywords>pathology</Keywords><Keywords>prevention &amp; control</Keywords><Keywords>therapy</Keywords><Keywords>Neo</Keywords><Reprint>Not in File</Reprint><Start_Page>3450</Start_Page><End_Page>3456</End_Page><Periodical>World J Gastroenterol</Periodical><Volume>16</Volume><Issue>27</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/23/2011 for SP0106</User_Def_3><ISSN_ISBN>20632451</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Hepatobiliary Surgery, Third Central Hospital, Tianjin 300170, China</Address><ZZ_JournalStdAbbrev><f name="System">World J Gastroenterol</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>30“Radiofrequency ablation did not decrease the number of overall recurrences, and had no effect on survival when compared with surgical resection in a selected group of patients. For patients who do not have the opportunity or are unwilling to accept surgical treatment, RFA is an acceptable means of palliative care.”NoNot reported Not reportedLiu et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Liu</Author><Year>2010</Year><RecNum>567950</RecNum><IDText>Laparoscopy or not: a meta-analysis of the surgical effects of laparoscopic versus open appendicectomy</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567950</Ref_ID><Title_Primary>Laparoscopy or not: a meta-analysis of the surgical effects of laparoscopic versus open appendicectomy</Title_Primary><Authors_Primary>Liu,Z.</Authors_Primary><Authors_Primary>Zhang,P.</Authors_Primary><Authors_Primary>Ma,Y.</Authors_Primary><Authors_Primary>Chen,H.</Authors_Primary><Authors_Primary>Zhou,Y.</Authors_Primary><Authors_Primary>Zhang,M.</Authors_Primary><Authors_Primary>Chu,Z.</Authors_Primary><Authors_Primary>Qin,H.</Authors_Primary><Date_Primary>2010/12</Date_Primary><Keywords>Appendectomy</Keywords><Keywords>*methods</Keywords><Keywords>Appendicitis</Keywords><Keywords>*surgery</Keywords><Keywords>Humans</Keywords><Keywords>*Laparoscopy</Keywords><Keywords>Length of Stay</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Treatment Outcome</Keywords><Reprint>Not in File</Reprint><Start_Page>362</Start_Page><End_Page>370</End_Page><Periodical>Surg Laparosc Endosc Percutan Tech</Periodical><Volume>20</Volume><Issue>6</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/31/2011 for SP0106</User_Def_3><ISSN_ISBN>21150411</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Surgery, Shanghai Jiao Tong University Affiliated Sixth People&apos;s Hospital, Shanghai, China</Address><ZZ_JournalStdAbbrev><f name="System">Surg Laparosc Endosc Percutan Tech</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>31“In conclusion, laparoscopic appendectomy may have advantages over open appendectomy in hospital stay and postoperative recovery. There is no convincing difference in complications and death rates.”NoNot reportedNot reportedLiu et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Zhang</Author><Year>2010</Year><RecNum>567635</RecNum><IDText>The role of renin-angiotensin system blockade therapy in the prevention of atrial fibrillation: a meta-analysis of randomized controlled trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567635</Ref_ID><Title_Primary>The role of renin-angiotensin system blockade therapy in the prevention of atrial fibrillation: a meta-analysis of randomized controlled trials</Title_Primary><Authors_Primary>Zhang,Y.</Authors_Primary><Authors_Primary>Zhang,P.</Authors_Primary><Authors_Primary>Mu,Y.</Authors_Primary><Authors_Primary>Gao,M.</Authors_Primary><Authors_Primary>Wang,J.R.</Authors_Primary><Authors_Primary>Wang,Y.</Authors_Primary><Authors_Primary>Su,L.Q.</Authors_Primary><Authors_Primary>Hou,Y.L.</Authors_Primary><Date_Primary>2010/10</Date_Primary><Keywords>Amiodarone</Keywords><Keywords>therapeutic use</Keywords><Keywords>Angiotensin II Type 1 Receptor Blockers</Keywords><Keywords>administration &amp; dosage</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Angiotensin-Converting Enzyme Inhibitors</Keywords><Keywords>administration &amp; dosage</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Anti-Arrhythmia Agents</Keywords><Keywords>therapeutic use</Keywords><Keywords>Atrial Fibrillation</Keywords><Keywords>compli</Keywords><Reprint>Not in File</Reprint><Start_Page>521</Start_Page><End_Page>531</End_Page><Periodical>Clin Pharmacol Ther</Periodical><Volume>88</Volume><Issue>4</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><ISSN_ISBN>20811347</ISSN_ISBN><Availability>SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Cardiology, Qianfoshan Hospital of Shandong University, Jinan City, China</Address><ZZ_JournalStdAbbrev><f name="System">Clin Pharmacol Ther</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>32“There is no significant difference in death rates of the treatment of HCC [hepatocellular carcinoma] in the groups of hepatectomy and RFA [Radio-frequency ablation], although recurrence of HCC may be lower in hepatectomy group. “RFA may have comparable results with surgical resection in patients in the therapeutic effect of ablation for the treatment of HCC, if recurrence of HCC after RFA could be timely detected and effectively treated.”YesNot reportedNot reportedLiu et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Wang</Author><Year>2010</Year><RecNum>553628</RecNum><IDText>High dose rate versus low dose rate intracavity brachytherapy for locally advanced uterine cervix cancer</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>553628</Ref_ID><Title_Primary>High dose rate versus low dose rate intracavity brachytherapy for locally advanced uterine cervix cancer</Title_Primary><Authors_Primary>Wang,X.</Authors_Primary><Authors_Primary>Liu,R.</Authors_Primary><Authors_Primary>Ma,B.</Authors_Primary><Authors_Primary>Yang,K.</Authors_Primary><Authors_Primary>Tian,J.</Authors_Primary><Authors_Primary>Jiang,L.</Authors_Primary><Authors_Primary>Bai,Z.G.</Authors_Primary><Authors_Primary>Hao,X.Y.</Authors_Primary><Authors_Primary>Wang,J.</Authors_Primary><Authors_Primary>Li,J.</Authors_Primary><Authors_Primary>Sun,S.L.</Authors_Primary><Authors_Primary>Yin,H.</Authors_Primary><Date_Primary>2010</Date_Primary><Keywords>Brachytherapy</Keywords><Keywords>*methods</Keywords><Keywords>Female</Keywords><Keywords>Humans</Keywords><Keywords>Neoplasm Recurrence,Local</Keywords><Keywords>Neoplasm Staging</Keywords><Keywords>Radiotherapy Dosage</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Uterine Cervical Neoplasms</Keywords><Keywords>mortality</Keywords><Keywords>pathology</Keywords><Keywords>*radiotherapy</Keywords><Reprint>Not in File</Reprint><Start_Page>CD007563</Start_Page><Periodical>Cochrane Database Syst Rev</Periodical><Issue>7</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011, MEDLINE - Ovid 11/18/2010</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20614461</ISSN_ISBN><Availability>AlexOnline_File , Sharepoint , SP0106 , W0247 , SRMLW247_111610 , SP0106_May5 , SP0106_Methods2</Availability><Address>Radiation Oncology Centre of Gan Su Tumour Hospital, Lanzhou University, 199 Dongang West Road, Lanzhou City, Gansu, China, 730000</Address><ZZ_JournalStdAbbrev><f name="System">Cochrane Database Syst Rev</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>33“This review showed no significant differences between HDR and LDR-ICBT when considering OS< DSS, RFS, local control rate, recurrence, metastasis and treatment related complications for women with cervical carcinoma. Due to some potential advantages of HDR-ICBT (rigid immobilization, outpatient treatment, patient convenience, accuracy of source and applicator positioning, individualized treatment) we recommend the use of HDR-ICBT for all clinical stages of cervix cancer.”NoNot reportedNot reportedMacedo et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Macedo</Author><Year>2010</Year><RecNum>567258</RecNum><IDText>Graded activity and graded exposure for persistent nonspecific low back pain: a systematic review</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567258</Ref_ID><Title_Primary>Graded activity and graded exposure for persistent nonspecific low back pain: a systematic review</Title_Primary><Authors_Primary>Macedo,L.G.</Authors_Primary><Authors_Primary>Smeets,R.J.</Authors_Primary><Authors_Primary>Maher,C.G.</Authors_Primary><Authors_Primary>Latimer,J.</Authors_Primary><Authors_Primary>McAuley,J.H.</Authors_Primary><Date_Primary>2010/6</Date_Primary><Keywords>Exercise Therapy</Keywords><Keywords>methods</Keywords><Keywords>Humans</Keywords><Keywords>Low Back Pain</Keywords><Keywords>*rehabilitation</Keywords><Keywords>Outcome and Process Assessment (Health Care)</Keywords><Keywords>*Physical Therapy Modalities</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Reprint>Not in File</Reprint><Start_Page>860</Start_Page><End_Page>879</End_Page><Periodical>Phys Ther</Periodical><Volume>90</Volume><Issue>6</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20395306</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>University of Sydney, PO Box M201, Missenden Rd, Camperdown, New South Wales 2050, Australia. lmacedo@.au</Address><ZZ_JournalStdAbbrev><f name="System">Phys Ther</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>34“The available evidence suggests that graded activity in the short term and intermediate term is slightly more effective than a minimal intervention but not more effective than other forms of exercise for persistent low back pain. The limited evidence suggests that graded exposure is as effective as minimal treatment or graded activity for persistent low back pain.”NoNot reportedNot reportedMachadoet al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Machado</Author><Year>2010</Year><RecNum>567440</RecNum><IDText>Comparison of SSRIs and SNRIs in major depressive disorder: a meta-analysis of head-to-head randomized clinical trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567440</Ref_ID><Title_Primary>Comparison of SSRIs and SNRIs in major depressive disorder: a meta-analysis of head-to-head randomized clinical trials</Title_Primary><Authors_Primary>Machado,M.</Authors_Primary><Authors_Primary>Einarson,T.R.</Authors_Primary><Date_Primary>2010/4</Date_Primary><Keywords>Adrenergic Uptake Inhibitors</Keywords><Keywords>adverse effects</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Adult</Keywords><Keywords>Depressive Disorder,Major</Keywords><Keywords>*drug therapy</Keywords><Keywords>Humans</Keywords><Keywords>Middle Aged</Keywords><Keywords>Models,Statistical</Keywords><Keywords>Patient Dropouts</Keywords><Keywords>statistics &amp; numerical data</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Remission Induction</Keywords><Keywords>meth</Keywords><Reprint>Not in File</Reprint><Start_Page>177</Start_Page><End_Page>188</End_Page><Periodical>J Clin Pharm Ther</Periodical><Volume>35</Volume><Issue>2</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/23/2011 for SP0106</User_Def_3><ISSN_ISBN>20456736</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Toronto Health Economics and Technology Assessment Collaborative (THETA), University of Toronto, Toronto, ON, Canada. m.machado@utoronto.ca</Address><ZZ_JournalStdAbbrev><f name="System">J Clin Pharm Ther</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>35“We conclude that the 5.7% (OR = 1.27) represents the difference in efficacy (i.e. remission rates) between SNRIs and SSRIs in treating patients with MDD. However, such efficacy difference was not considered clinically relevant. This result was based on some clinical assumptions, such as ideal clinical conditions (i.e. 8 to 12 week treatment duration for MDD), research design (i.e. head to head trials), and outcome measure (i.e. remission rates). As well, the present meta-analysis examines a wide variety of pharmacological treatments, including the newest drugs in the classes of interest, duloxetine and escitalopram. Other meta-analyses confirmed the results found here.”NoNot reportedNot reportedMeier et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Meier</Author><Year>2010</Year><RecNum>567614</RecNum><IDText>Chest compressions before defibrillation for out-of-hospital cardiac arrest: a meta-analysis of randomized controlled clinical trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567614</Ref_ID><Title_Primary>Chest compressions before defibrillation for out-of-hospital cardiac arrest: a meta-analysis of randomized controlled clinical trials</Title_Primary><Authors_Primary>Meier,P.</Authors_Primary><Authors_Primary>Baker,P.</Authors_Primary><Authors_Primary>Jost,D.</Authors_Primary><Authors_Primary>Jacobs,I.</Authors_Primary><Authors_Primary>Henzi,B.</Authors_Primary><Authors_Primary>Knapp,G.</Authors_Primary><Authors_Primary>Sasson,C.</Authors_Primary><Date_Primary>2010</Date_Primary><Keywords>Cardiopulmonary Resuscitation</Keywords><Keywords>*standards</Keywords><Keywords>Electric Countershock</Keywords><Keywords>Emergency Medical Services</Keywords><Keywords>*methods</Keywords><Keywords>Heart Massage</Keywords><Keywords>*standards</Keywords><Keywords>Humans</Keywords><Keywords>Odds Ratio</Keywords><Keywords>Out-of-Hospital Cardiac Arrest</Keywords><Keywords>*mortality</Keywords><Keywords>*therapy</Keywords><Keywords>Practice Guidelines as Topic</Keywords><Keywords>Randomized Controlled Trials as T</Keywords><Reprint>Not in File</Reprint><Start_Page>52</Start_Page><Periodical>BMC Med</Periodical><Volume>8</Volume><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/23/2011 for SP0106</User_Def_3><ISSN_ISBN>20828395</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>University of Michigan Medical Center, Cardiovascular Medicine, Ann Arbor, Michigan, USA. pascalmeier74@</Address><ZZ_JournalStdAbbrev><f name="System">BMC Med</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>6“Current evidence does not support the notion that chest compression first prior to defibrillation improves the outcome of patients in out-of-hospital cardiac arrest. It appears that both treatments are equivalent. However, subgroup analyses indicate that chest compression first may be beneficial for cardiac arrests with a prolonged response time.”YesNot reportedThe authors report that their conclusions were based on no treatment effect with fairly narrow confidence intervals (precision) and with very little heterogeneity. Milito et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Milito</Author><Year>2010</Year><RecNum>567126</RecNum><IDText>Haemorrhoidectomy with Ligasure vs conventional excisional techniques: meta-analysis of randomized controlled trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567126</Ref_ID><Title_Primary>Haemorrhoidectomy with Ligasure vs conventional excisional techniques: meta-analysis of randomized controlled trials</Title_Primary><Authors_Primary>Milito,G.</Authors_Primary><Authors_Primary>Cadeddu,F.</Authors_Primary><Authors_Primary>Muzi,M.G.</Authors_Primary><Authors_Primary>Nigro,C.</Authors_Primary><Authors_Primary>Farinon,A.M.</Authors_Primary><Date_Primary>2010/2</Date_Primary><Keywords>Electrocoagulation</Keywords><Keywords>adverse effects</Keywords><Keywords>*methods</Keywords><Keywords>Hemorrhoids</Keywords><Keywords>*surgery</Keywords><Keywords>Humans</Keywords><Keywords>Pain,Postoperative</Keywords><Keywords>etiology</Keywords><Keywords>Postoperative Hemorrhage</Keywords><Keywords>etiology</Keywords><Keywords>Recurrence</Keywords><Keywords>*Surgical Staplers</Keywords><Keywords>Wound Healing</Keywords><Reprint>Not in File</Reprint><Start_Page>85</Start_Page><End_Page>93</End_Page><Periodical>Colorectal Dis</Periodical><Volume>12</Volume><Issue>2</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/31/2011 for SP0106</User_Def_3><ISSN_ISBN>19220374</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Surgery, University Hospital Tor Vergata, Rome, Italy. giovanni.milito@virgilio.it</Address><ZZ_JournalStdAbbrev><f name="System">Colorectal Dis</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>36“There was no significant difference in the proportion of patients cured after LigaSure haemorrhoidectomy or other excisional techniques. Patients treated with LigaSure had a significantly shorter operative time, postoperative pain, wound healing and time off work than the patients submitted to excisional techniques. Postoperative bleeding did not significantly differ between the two groups.” “Our meta-analysis shows that LigaSure haemorrhoidectomy is a fast procedure characterized by limited postoperative pain, short hospitalization, fast wound healing and convalescence.”NoNot reportedNot reportedMurphy et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Murphy</Author><Year>2010</Year><RecNum>567419</RecNum><IDText>Comparison of the postoperative analgesic efficacy of intravenous patient-controlled analgesia with tramadol to intravenous patient-controlled analgesia with opioids</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567419</Ref_ID><Title_Primary>Comparison of the postoperative analgesic efficacy of intravenous patient-controlled analgesia with tramadol to intravenous patient-controlled analgesia with opioids</Title_Primary><Authors_Primary>Murphy,J.D.</Authors_Primary><Authors_Primary>Yan,D.</Authors_Primary><Authors_Primary>Hanna,M.N.</Authors_Primary><Authors_Primary>Bravos,E.D.</Authors_Primary><Authors_Primary>Isaac,G.R.</Authors_Primary><Authors_Primary>Eng,C.A.</Authors_Primary><Authors_Primary>Wu,C.L.</Authors_Primary><Date_Primary>2010/3</Date_Primary><Keywords>Abdominal Pain</Keywords><Keywords>*drug therapy</Keywords><Keywords>Adult</Keywords><Keywords>*Analgesia,Patient-Controlled</Keywords><Keywords>Analgesics,Opioid</Keywords><Keywords>administration &amp; dosage</Keywords><Keywords>adverse effects</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Fentanyl</Keywords><Keywords>administration &amp; dosage</Keywords><Keywords>adverse effects</Keywords><Keywords>therapeutic use</Keywords><Keywords>Humans</Keywords><Keywords>Infusion Pumps</Keywords><Keywords>Morphine</Keywords><Keywords>administration &amp;</Keywords><Reprint>Not in File</Reprint><Start_Page>141</Start_Page><End_Page>147</End_Page><Periodical>J Opioid Manag</Periodical><Volume>6</Volume><Issue>2</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20481179</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA</Address><ZZ_JournalStdAbbrev><f name="System">J Opioid Manag</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>37“In summary, we have undertaken a meta-analysis to examine RCTs comparing IV PCA tramadol to IV PCA opioids in the postoperative period and found no difference in pain scores between the two regimens. We did find differences in the profile of side effects of the two drugs, which should be taken into consideration if both analgesic regimens are available for use. Further studies may be needed to assess the relative safety and analgesic efficacy, particularly for severe pain, of the two regimens.”NoNot reportedNot reportedMyers et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Lanitis</Author><Year>2010</Year><RecNum>567343</RecNum><IDText>Comparison of skin-sparing mastectomy versus non-skin-sparing mastectomy for breast cancer: a meta-analysis of observational studies</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567343</Ref_ID><Title_Primary>Comparison of skin-sparing mastectomy versus non-skin-sparing mastectomy for breast cancer: a meta-analysis of observational studies</Title_Primary><Authors_Primary>Lanitis,S.</Authors_Primary><Authors_Primary>Tekkis,P.P.</Authors_Primary><Authors_Primary>Sgourakis,G.</Authors_Primary><Authors_Primary>Dimopoulos,N.</Authors_Primary><Authors_Primary>Al,Mufti R.</Authors_Primary><Authors_Primary>Hadjiminas,D.J.</Authors_Primary><Date_Primary>2010/4</Date_Primary><Keywords>Breast Neoplasms</Keywords><Keywords>pathology</Keywords><Keywords>*surgery</Keywords><Keywords>Female</Keywords><Keywords>Humans</Keywords><Keywords>Mammaplasty</Keywords><Keywords>Mastectomy</Keywords><Keywords>*methods</Keywords><Keywords>Neoplasm Metastasis</Keywords><Keywords>Neoplasm Recurrence,Local</Keywords><Reprint>Not in File</Reprint><Start_Page>632</Start_Page><End_Page>639</End_Page><Periodical>Ann Surg</Periodical><Volume>251</Volume><Issue>4</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/23/2011 for SP0106</User_Def_3><ISSN_ISBN>20224371</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>General Surgery Unit, Imperial College Healthcare NHS Trust, St. Mary&apos;s Hospital, London, United Kingdom. drlanitis@</Address><ZZ_JournalStdAbbrev><f name="System">Ann Surg</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>9“Reports indicate intraspinal analgesia is equally or more effective than conventional medical management and often associated with fewer side effects.” “Intraspinal techniques monitored by an interprofessional health care team should be included as part of a comprehensive cancer pain management program.”YesNot reportedNot reportedPan et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Pan</Author><Year>2010</Year><RecNum>567863</RecNum><IDText>A meta-analysis of randomized trials on clinical outcomes of paclitaxel-eluting stents versus bare-metal stents in ST-segment elevation myocardial infarction patients</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567863</Ref_ID><Title_Primary>A meta-analysis of randomized trials on clinical outcomes of paclitaxel-eluting stents versus bare-metal stents in ST-segment elevation myocardial infarction patients</Title_Primary><Authors_Primary>Pan,X.H.</Authors_Primary><Authors_Primary>Chen,Y.X.</Authors_Primary><Authors_Primary>Xiang,M.X.</Authors_Primary><Authors_Primary>Xu,G.</Authors_Primary><Authors_Primary>Wang,J.A.</Authors_Primary><Date_Primary>2010/10</Date_Primary><Keywords>*Angioplasty,Balloon,Coronary</Keywords><Keywords>Antineoplastic Agents,Phytogenic</Keywords><Keywords>*administration &amp; dosage</Keywords><Keywords>*Drug-Eluting Stents</Keywords><Keywords>Electrocardiography</Keywords><Keywords>Humans</Keywords><Keywords>Myocardial Infarction</Keywords><Keywords>*therapy</Keywords><Keywords>Paclitaxel</Keywords><Keywords>*administration &amp; dosage</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>*Stents</Keywords><Keywords>Tre</Keywords><Reprint>Not in File</Reprint><Start_Page>754</Start_Page><End_Page>761</End_Page><Periodical>J Zhejiang Univ Sci B</Periodical><Volume>11</Volume><Issue>10</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/25/2011 for SP0106</User_Def_3><ISSN_ISBN>20872982</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Cardiology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China</Address><ZZ_JournalStdAbbrev><f name="System">J Zhejiang Univ Sci B</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>38Pooled analyses indicated no significant difference between bare metal and drug eluting stents for the following outcomes: 1-year mortality, recurrent myocardial infarction, and rate of stent thrombosis. Analysis did show that drug eluting stents resulted in significantly lower rate of revascularization than bare metal stents. The authors concluded that “the results show that [drug eluting stents] improved clinical outcomes in [patients with ST-segment elevation myocardial infarction] with a decreased need for repeat revascularization and no concerns for safety.”NoNot reportedNot reportedRiemsa et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Riemsma</Author><Year>2010</Year><RecNum>567655</RecNum><IDText>Systematic Review of topotecan (Hycamtin) in relapsed small cell lung cancer</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567655</Ref_ID><Title_Primary>Systematic Review of topotecan (Hycamtin) in relapsed small cell lung cancer</Title_Primary><Authors_Primary>Riemsma,R.</Authors_Primary><Authors_Primary>Simons,J.P.</Authors_Primary><Authors_Primary>Bashir,Z.</Authors_Primary><Authors_Primary>Gooch,C.L.</Authors_Primary><Authors_Primary>Kleijnen,J.</Authors_Primary><Date_Primary>2010</Date_Primary><Keywords>Humans</Keywords><Keywords>Lung Neoplasms</Keywords><Keywords>*drug therapy</Keywords><Keywords>pathology</Keywords><Keywords>Neoplasm Recurrence,Local</Keywords><Keywords>*drug therapy</Keywords><Keywords>pathology</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Small Cell Lung Carcinoma</Keywords><Keywords>*drug therapy</Keywords><Keywords>pathology</Keywords><Keywords>Topoisomerase Inhibitors</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Topotecan</Keywords><Keywords>*therapeutic use</Keywords><Reprint>Not in File</Reprint><Start_Page>436</Start_Page><Periodical>BMC Cancer</Periodical><Volume>10</Volume><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/23/2011 for SP0106</User_Def_3><ISSN_ISBN>20716361</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Kleijnen Systematic Reviews Ltd,, York, UK. rob@systematic-</Address><ZZ_JournalStdAbbrev><f name="System">BMC Cancer</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>8“From the evidence discussed, it is evident that oral topotecan has similar efficacy to IV topotecan (direct comparison) and CAV (indirect comparison). There is no further evidence base of direct or possible indirect comparisons for other comparators than CAV or either oral or IV topotecan.”YesNot reportedNot reportedSbruzzi et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Sbruzzi</Author><Year>2010</Year><RecNum>567518</RecNum><IDText>Functional electrical stimulation in the treatment of patients with chronic heart failure: a meta-analysis of randomized controlled trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567518</Ref_ID><Title_Primary>Functional electrical stimulation in the treatment of patients with chronic heart failure: a meta-analysis of randomized controlled trials</Title_Primary><Authors_Primary>Sbruzzi,G.</Authors_Primary><Authors_Primary>Ribeiro,R.A.</Authors_Primary><Authors_Primary>Schaan,B.D.</Authors_Primary><Authors_Primary>Signori,L.U.</Authors_Primary><Authors_Primary>Silva,A.M.</Authors_Primary><Authors_Primary>Irigoyen,M.C.</Authors_Primary><Authors_Primary>Plentz,R.D.</Authors_Primary><Date_Primary>2010/6</Date_Primary><Keywords>Adult</Keywords><Keywords>Aged</Keywords><Keywords>Chronic Disease</Keywords><Keywords>*Electric Stimulation Therapy</Keywords><Keywords>Evidence-Based Medicine</Keywords><Keywords>Exercise Therapy</Keywords><Keywords>Exercise Tolerance</Keywords><Keywords>Female</Keywords><Keywords>Heart Failure</Keywords><Keywords>physiopathology</Keywords><Keywords>*rehabilitation</Keywords><Keywords>Humans</Keywords><Keywords>Male</Keywords><Keywords>Middle Aged</Keywords><Keywords>Muscle Strength</Keywords><Keywords>Oxygen Consumption</Keywords><Keywords>Randomized Controlled Tria</Keywords><Reprint>Not in File</Reprint><Start_Page>254</Start_Page><End_Page>260</End_Page><Periodical>Eur J Cardiovasc Prev Rehabil</Periodical><Volume>17</Volume><Issue>3</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 6/6/2011 for SP0106</User_Def_3><ISSN_ISBN>20560163</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Instituto de Cardiologia do Rio Grande do Sul/Fundacao Universitaria de Cardiologia, Porto Alegre, RS, Brazil</Address><ZZ_JournalStdAbbrev><f name="System">Eur J Cardiovasc Prev Rehabil</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>39“Treatment with [functional electrical stimulation] provides a similar gain in the distance of the 6-min walk test and in the muscle strength when compared to [conventional exercise, CA], but a small gain in the peak VO2. Thus, FES may be an alternative in relation with CA for patients with [chronic heart failure].”YesNot reported Not reportedSgourakiset al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Sgourakis</Author><Year>2010</Year><RecNum>567450</RecNum><IDText>The use of self-expanding stents in esophageal and gastroesophageal junction cancer palliation: a meta-analysis and meta-regression analysis of outcomes</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567450</Ref_ID><Title_Primary>The use of self-expanding stents in esophageal and gastroesophageal junction cancer palliation: a meta-analysis and meta-regression analysis of outcomes</Title_Primary><Authors_Primary>Sgourakis,G.</Authors_Primary><Authors_Primary>Gockel,I.</Authors_Primary><Authors_Primary>Radtke,A.</Authors_Primary><Authors_Primary>Dedemadi,G.</Authors_Primary><Authors_Primary>Goumas,K.</Authors_Primary><Authors_Primary>Mylona,S.</Authors_Primary><Authors_Primary>Lang,H.</Authors_Primary><Authors_Primary>Tsiamis,A.</Authors_Primary><Authors_Primary>Karaliotas,C.</Authors_Primary><Date_Primary>2010/11</Date_Primary><Keywords>Brachytherapy</Keywords><Keywords>Esophageal Neoplasms</Keywords><Keywords>mortality</Keywords><Keywords>radiotherapy</Keywords><Keywords>*therapy</Keywords><Keywords>*Esophagogastric Junction</Keywords><Keywords>Humans</Keywords><Keywords>Odds Ratio</Keywords><Keywords>Palliative Care</Keywords><Keywords>Publication Bias</Keywords><Keywords>ROC Curve</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>*Stents</Keywords><Keywords>Treatment Outcome</Keywords><Reprint>Not in File</Reprint><Start_Page>3018</Start_Page><End_Page>3030</End_Page><Periodical>Dig Dis Sci</Periodical><Volume>55</Volume><Issue>11</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20440646</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>2nd Surgical Department and Surgical Oncology Unit, Korgialenio-Benakio Red Cross Hospital, 11 Mantzarou Str., Neo Psychiko, Athens, Greece. ggsgourakis@yahoo.gr</Address><ZZ_JournalStdAbbrev><f name="System">Dig Dis Sci</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>40“Conventional self-expanding stents and anti-reflux stents are equally effective. Although the risk difference for 1-year survival favored locoregional palliative treatment modalities, the latter were associated with a higher number of patients requiring reintervention.”YesNot reportedNot reportedSimpsonet al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Simpson</Author><Year>2010</Year><RecNum>567604</RecNum><IDText>Delayed versus immediate defibrillation for out-of-hospital cardiac arrest due to ventricular fibrillation: A systematic review and meta-analysis of randomised controlled trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567604</Ref_ID><Title_Primary>Delayed versus immediate defibrillation for out-of-hospital cardiac arrest due to ventricular fibrillation: A systematic review and meta-analysis of randomised controlled trials</Title_Primary><Authors_Primary>Simpson,P.M.</Authors_Primary><Authors_Primary>Goodger,M.S.</Authors_Primary><Authors_Primary>Bendall,J.C.</Authors_Primary><Date_Primary>2010/8</Date_Primary><Keywords>Electric Countershock</Keywords><Keywords>*methods</Keywords><Keywords>Emergency Medical Services</Keywords><Keywords>*methods</Keywords><Keywords>Heart Arrest</Keywords><Keywords>etiology</Keywords><Keywords>*therapy</Keywords><Keywords>Humans</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Time Factors</Keywords><Keywords>Ventricular Fibrillation</Keywords><Keywords>*complications</Keywords><Keywords>physiopathology</Keywords><Keywords>therapy</Keywords><Reprint>Not in File</Reprint><Start_Page>925</Start_Page><End_Page>931</End_Page><Periodical>Resuscitation</Periodical><Volume>81</Volume><Issue>8</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/25/2011 for SP0106</User_Def_3><ISSN_ISBN>20483525</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Ambulance Research Institute, Ambulance Service of New South Wales, Locked Bag 105, Rozelle, Sydney, NSW 2039, Australia. psimpson@ambulance..au</Address><ZZ_JournalStdAbbrev><f name="System">Resuscitation</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>41“Delaying initial defibrillation to allow a short period of CPR in out-of-hospital cardiac arrest due to VF demonstrated no benefit over immediate defibrillation for survival to hospital discharge irrespective of response time. There is no evidence that CPR before defibrillation is harmful. Based on the existing evidence, EMS jurisdictions are justified continuing with current practice using either defibrillation strategy.”NoNot reportedNot reportedSquizzatoet al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Squizzato</Author><Year>2010</Year><RecNum>567143</RecNum><IDText>Antithrombotic and fibrinolytic drugs for retinal vein occlusion: a systematic review and a call for action</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567143</Ref_ID><Title_Primary>Antithrombotic and fibrinolytic drugs for retinal vein occlusion: a systematic review and a call for action</Title_Primary><Authors_Primary>Squizzato,A.</Authors_Primary><Authors_Primary>Manfredi,E.</Authors_Primary><Authors_Primary>Bozzato,S.</Authors_Primary><Authors_Primary>Dentali,F.</Authors_Primary><Authors_Primary>Ageno,W.</Authors_Primary><Date_Primary>2010/2</Date_Primary><Keywords>Aspirin</Keywords><Keywords>therapeutic use</Keywords><Keywords>Drug Evaluation</Keywords><Keywords>Fibrinolytic Agents</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Heparin,Low-Molecular-Weight</Keywords><Keywords>therapeutic use</Keywords><Keywords>Humans</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Retinal Vein Occlusion</Keywords><Keywords>*drug therapy</Keywords><Keywords>Ticlopidine</Keywords><Keywords>therapeutic use</Keywords><Keywords>Treatment Outcome</Keywords><Keywords>Visu</Keywords><Reprint>Not in File</Reprint><Start_Page>271</Start_Page><End_Page>276</End_Page><Periodical>Thromb Haemost</Periodical><Volume>103</Volume><Issue>2</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/31/2011 for SP0106</User_Def_3><ISSN_ISBN>20126837</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Medicina I - Ospedale di Circolo, Viale Borri 57, 21100 Varese, Italy. alexsquizzo@libero.it</Address><ZZ_JournalStdAbbrev><f name="System">Thromb Haemost</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>12“Antithrombotic drugs may play a role in the treatment of the acute phase RVO, at least in some patient’s categories. However, given the complexity of this condition, a multidisciplinary approach, concomitantly including ophthalmologic and antithrombotic treatment strategies, should be assessed to improve the management of what we can call a still ‘orphan’ disease.”NoNot reportedNot reportedSunkara et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Sunkara</Author><Year>2010</Year><RecNum>567542</RecNum><IDText>The influence of delayed blastocyst formation on the outcome of frozen-thawed blastocyst transfer: a systematic review and meta-analysis</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567542</Ref_ID><Title_Primary>The influence of delayed blastocyst formation on the outcome of frozen-thawed blastocyst transfer: a systematic review and meta-analysis</Title_Primary><Authors_Primary>Sunkara,S.K.</Authors_Primary><Authors_Primary>Siozos,A.</Authors_Primary><Authors_Primary>Bolton,V.N.</Authors_Primary><Authors_Primary>Khalaf,Y.</Authors_Primary><Authors_Primary>Braude,P.R.</Authors_Primary><Authors_Primary>El-Toukhy,T.</Authors_Primary><Date_Primary>2010/8</Date_Primary><Keywords>Abortion,Spontaneous</Keywords><Keywords>epidemiology</Keywords><Keywords>Birth Rate</Keywords><Keywords>*Blastocyst</Keywords><Keywords>*Cryopreservation</Keywords><Keywords>*Embryo Transfer</Keywords><Keywords>*Embryonic Development</Keywords><Keywords>Female</Keywords><Keywords>Fertilization in Vitro</Keywords><Keywords>Humans</Keywords><Keywords>Pregnancy</Keywords><Keywords>Pregnancy Outcome</Keywords><Keywords>Time Factors</Keywords><Reprint>Not in File</Reprint><Start_Page>1906</Start_Page><End_Page>1915</End_Page><Periodical>Hum Reprod</Periodical><Volume>25</Volume><Issue>8</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/31/2011 for SP0106</User_Def_3><ISSN_ISBN>20542896</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Guy&apos;s and St Thomas&apos; Hospitals NHS Foundation Trust, Assisted Conception Unit, 11th Floor, Tower Wing Guy&apos;s Hospital Great Maze Pond, London SE1 9RT, UK. sksunkara@</Address><ZZ_JournalStdAbbrev><f name="System">Hum Reprod</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>42“Slower developing blastocysts cryopreserved on Day 6 but at the same stage of development as those developing to the blastocyst stage on Day 5 have similar clinical pregnancy and ongoing pregnancy/live birth rates following frozen-thawed blastocyst transfers.”YesNot reportedNot reportedTamayo et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Tamayo</Author><Year>2010</Year><RecNum>567139</RecNum><IDText>Level of response and safety of pharmacological monotherapy in the treatment of acute bipolar I disorder phases: a systematic review and meta-analysis</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567139</Ref_ID><Title_Primary>Level of response and safety of pharmacological monotherapy in the treatment of acute bipolar I disorder phases: a systematic review and meta-analysis</Title_Primary><Authors_Primary>Tamayo,J.M.</Authors_Primary><Authors_Primary>Zarate,C.A.,Jr.</Authors_Primary><Authors_Primary>Vieta,E.</Authors_Primary><Authors_Primary>Vazquez,G.</Authors_Primary><Authors_Primary>Tohen,M.</Authors_Primary><Date_Primary>2010/7</Date_Primary><Keywords>Acute Disease</Keywords><Keywords>Animals</Keywords><Keywords>Antidepressive Agents</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Bipolar Disorder</Keywords><Keywords>*drug therapy</Keywords><Keywords>Databases,Factual</Keywords><Keywords>statistics &amp; numerical data</Keywords><Keywords>*Drug Evaluation</Keywords><Keywords>Humans</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Reprint>Not in File</Reprint><Start_Page>813</Start_Page><End_Page>832</End_Page><Periodical>Int J Neuropsychopharmacol</Periodical><Volume>13</Volume><Issue>6</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20128953</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Psychiatry, CES University, Medellin, Colombia. tamayojm@</Address><ZZ_JournalStdAbbrev><f name="System">Int J Neuropsychopharmacol</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>7“Although there are patients who are unresponsive to acute treatment with monotherapy, these results suggest that MDRs should be considered as a first therapeutic option for the treatment of nonrefractory manic episodes. This approach may result in the reduction of direct costs of medications, the number and magnitude of AEs and may improve treatment adherence and patient compliance. For depressive episodes, the new data with SGAs (quetiapine and olanzapine) suggest that these MDR, especially quetiapine, are efficacious and well tolerated.”NoNot reportedNot reportedTamhaneet al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Tamhane</Author><Year>2010</Year><RecNum>567366</RecNum><IDText>Safety and efficacy of thrombectomy in patients undergoing primary percutaneous coronary intervention for acute ST elevation MI: a meta-analysis of randomized controlled trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567366</Ref_ID><Title_Primary>Safety and efficacy of thrombectomy in patients undergoing primary percutaneous coronary intervention for acute ST elevation MI: a meta-analysis of randomized controlled trials</Title_Primary><Authors_Primary>Tamhane,U.U.</Authors_Primary><Authors_Primary>Chetcuti,S.</Authors_Primary><Authors_Primary>Hameed,I.</Authors_Primary><Authors_Primary>Grossman,P.M.</Authors_Primary><Authors_Primary>Moscucci,M.</Authors_Primary><Authors_Primary>Gurm,H.S.</Authors_Primary><Date_Primary>2010</Date_Primary><Keywords>Aged</Keywords><Keywords>*Angioplasty,Balloon,Coronary</Keywords><Keywords>Female</Keywords><Keywords>Humans</Keywords><Keywords>Male</Keywords><Keywords>Middle Aged</Keywords><Keywords>Myocardial Infarction</Keywords><Keywords>*mortality</Keywords><Keywords>*therapy</Keywords><Keywords>*Randomized Controlled Trials as Topic</Keywords><Keywords>Stroke</Keywords><Keywords>etiology</Keywords><Keywords>mortality</Keywords><Keywords>Thrombectomy</Keywords><Keywords>*adverse effects</Keywords><Keywords>Thrombolytic Therapy</Keywords><Keywords>instrumentation</Keywords><Reprint>Not in File</Reprint><Start_Page>10</Start_Page><Periodical>BMC Cardiovasc Disord</Periodical><Volume>10</Volume><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/23/2011 for SP0106</User_Def_3><ISSN_ISBN>20187958</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA</Address><ZZ_JournalStdAbbrev><f name="System">BMC Cardiovasc Disord</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>43“Thrombectomy devices appear to improve markers of myocardial perfusion in patients undergoing primary PCI, with no difference in overall 30-day mortality but an increased likelihood of stroke. The clinical benefits of thrombectomy appear to be influenced by the device type with a trend towards survival benefit with MAT and worsening outcome with mechanical devices.”NoNot reportedNot reportedTang et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Tang</Author><Year>2010</Year><RecNum>567765</RecNum><IDText>Outcomes of MTA as root-end filling in endodontic surgery: a systematic review</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567765</Ref_ID><Title_Primary>Outcomes of MTA as root-end filling in endodontic surgery: a systematic review</Title_Primary><Authors_Primary>Tang,Y.</Authors_Primary><Authors_Primary>Li,X.</Authors_Primary><Authors_Primary>Yin,S.</Authors_Primary><Date_Primary>2010/7</Date_Primary><Keywords>Aluminum Compounds</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Apicoectomy</Keywords><Keywords>methods</Keywords><Keywords>Calcium Compounds</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Controlled Clinical Trials as Topic</Keywords><Keywords>Drug Combinations</Keywords><Keywords>Humans</Keywords><Keywords>Oxides</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Placebos</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Retrograde Obturation</Keywords><Keywords>*methods</Keywords><Keywords>R</Keywords><Reprint>Not in File</Reprint><Start_Page>557</Start_Page><End_Page>566</End_Page><Periodical>Quintessence Int</Periodical><Volume>41</Volume><Issue>7</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 6/6/2011 for SP0106</User_Def_3><ISSN_ISBN>20614042</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Endodontics, West China School of Dentistry, Sichuan University, Chengdu</Address><ZZ_JournalStdAbbrev><f name="System">Quintessence Int</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>4“The results of this systematic review indicate that the outcomes of MTA as root-end filling are significantly better than amalgam and pure gutta-percha, but are similar to IRM.”YesNot reportedNot reportedTesta et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Testa</Author><Year>2010</Year><RecNum>567851</RecNum><IDText>Drug eluting stents versus bare metal stents in the treatment of saphenous vein graft disease: a systematic review and meta-analysis</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567851</Ref_ID><Title_Primary>Drug eluting stents versus bare metal stents in the treatment of saphenous vein graft disease: a systematic review and meta-analysis</Title_Primary><Authors_Primary>Testa,L.</Authors_Primary><Authors_Primary>Agostoni,P.</Authors_Primary><Authors_Primary>Vermeersch,P.</Authors_Primary><Authors_Primary>Biondi-Zoccai,G.</Authors_Primary><Authors_Primary>Van,Gaal W.</Authors_Primary><Authors_Primary>Bhindi,R.</Authors_Primary><Authors_Primary>Brilakis,E.</Authors_Primary><Authors_Primary>Latini,R.A.</Authors_Primary><Authors_Primary>Laudisa,M.L.</Authors_Primary><Authors_Primary>Pizzocri,S.</Authors_Primary><Authors_Primary>Lanotte,S.</Authors_Primary><Authors_Primary>Brambilla,N.</Authors_Primary><Authors_Primary>Banning,A.</Authors_Primary><Authors_Primary>Bedogni,F.</Authors_Primary><Date_Primary>2010/9</Date_Primary><Keywords>Angioplasty,Balloon,Coronary</Keywords><Keywords>*instrumentation</Keywords><Keywords>Coronary Artery Bypass</Keywords><Keywords>*adverse effects</Keywords><Keywords>*Drug-Eluting Stents</Keywords><Keywords>Follow-Up Studies</Keywords><Keywords>Graft Occlusion,Vascular</Keywords><Keywords>*therapy</Keywords><Keywords>Humans</Keywords><Keywords>Saphenous Vein</Keywords><Keywords>*transplantation</Keywords><Keywords>*Stents</Keywords><Reprint>Not in File</Reprint><Start_Page>527</Start_Page><End_Page>536</End_Page><Periodical>EuroIntervention</Periodical><Volume>6</Volume><Issue>4</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20884442</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Interventional Cardiology, Istituto clinico S. Ambrogio, Milan, Italy. luctes@</Address><ZZ_JournalStdAbbrev><f name="System">EuroIntervention</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>44“Use of DES in SVG substantially reduces both TVR and TLR. These data also demonstrates that using DES in SVG is safe and contradicts previous reports of potential risks.”NoNot reportedNot reportedValachis et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Valachis</Author><Year>2010</Year><RecNum>567349</RecNum><IDText>Partial breast irradiation or whole breast radiotherapy for early breast cancer: a meta-analysis of randomized controlled trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567349</Ref_ID><Title_Primary>Partial breast irradiation or whole breast radiotherapy for early breast cancer: a meta-analysis of randomized controlled trials</Title_Primary><Authors_Primary>Valachis,A.</Authors_Primary><Authors_Primary>Mauri,D.</Authors_Primary><Authors_Primary>Polyzos,N.P.</Authors_Primary><Authors_Primary>Mavroudis,D.</Authors_Primary><Authors_Primary>Georgoulias,V.</Authors_Primary><Authors_Primary>Casazza,G.</Authors_Primary><Date_Primary>2010/5</Date_Primary><Keywords>Breast</Keywords><Keywords>radiation effects</Keywords><Keywords>Breast Neoplasms</Keywords><Keywords>mortality</Keywords><Keywords>*radiotherapy</Keywords><Keywords>Female</Keywords><Keywords>Humans</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Reprint>Not in File</Reprint><Start_Page>245</Start_Page><End_Page>251</End_Page><Periodical>Breast J</Periodical><Volume>16</Volume><Issue>3</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/23/2011 for SP0106</User_Def_3><ISSN_ISBN>20210799</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Medical Oncology, University General Hospital of Heraklion, Greece. valachis@</Address><ZZ_JournalStdAbbrev><f name="System">Breast J</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>45“Partial breast irradiation [PBI] does not seem to jeopardize survival and may be used as an alternative to whole breast-radiation [WBRT]. Risk for death is comparable among both treatment modalities.”YesNot reportedNot reportedVasiliadiset al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Vasiliadis</Author><Year>2010</Year><RecNum>567142</RecNum><IDText>Autologous chondrocyte implantation for the treatment of cartilage lesions of the knee: a systematic review of randomized studies</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567142</Ref_ID><Title_Primary>Autologous chondrocyte implantation for the treatment of cartilage lesions of the knee: a systematic review of randomized studies</Title_Primary><Authors_Primary>Vasiliadis,H.S.</Authors_Primary><Authors_Primary>Wasiak,J.</Authors_Primary><Authors_Primary>Salanti,G.</Authors_Primary><Date_Primary>2010/12</Date_Primary><Keywords>Cartilage,Articular</Keywords><Keywords>*injuries</Keywords><Keywords>pathology</Keywords><Keywords>*surgery</Keywords><Keywords>Chondrocytes</Keywords><Keywords>*transplantation</Keywords><Keywords>Humans</Keywords><Keywords>Orthopedic Procedures</Keywords><Keywords>Outcome Assessment (Health Care)</Keywords><Keywords>Pain Measurement</Keywords><Keywords>Postoperative Care</Keywords><Keywords>Postoperative Complications</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Research De</Keywords><Reprint>Not in File</Reprint><Start_Page>1645</Start_Page><End_Page>1655</End_Page><Periodical>Knee Surg Sports Traumatol Arthrosc</Periodical><Volume>18</Volume><Issue>12</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/31/2011 for SP0106</User_Def_3><ISSN_ISBN>20127071</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Orthopaedics, School of Medicine, University of Ioannina, Orthopaedic Sports Medicine Center, Ioannina, Greece. vasiliadismd@</Address><ZZ_JournalStdAbbrev><f name="System">Knee Surg Sports Traumatol Arthrosc</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>15“Complications rates were comparable between interventions except from an increase rate of graft hypertrophies after ACI with periosteum. There is insufficient data to say whether ACI is superior to other treatment strategies. More high quality studies and harmonization in the reported outcomes are needed before specific suggestions for practice can be made.”YesNot reportedNot reportedVermeulanet al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Vermeulen</Author><Year>2010</Year><RecNum>567735</RecNum><IDText>Benefit and harm of iodine in wound care: a systematic review</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567735</Ref_ID><Title_Primary>Benefit and harm of iodine in wound care: a systematic review</Title_Primary><Authors_Primary>Vermeulen,H.</Authors_Primary><Authors_Primary>Westerbos,S.J.</Authors_Primary><Authors_Primary>Ubbink,D.T.</Authors_Primary><Date_Primary>2010/11</Date_Primary><Keywords>Administration,Topical</Keywords><Keywords>Anti-Infective Agents,Local</Keywords><Keywords>administration &amp; dosage</Keywords><Keywords>*adverse</Keywords><Keywords>Humans</Keywords><Keywords>Iodine</Keywords><Keywords>administration &amp; dosage</Keywords><Keywords>*adverse effects</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Treatment Outcome</Keywords><Keywords>Wound Infection</Keywords><Keywords>*drug therapy</Keywords><Reprint>Not in File</Reprint><Start_Page>191</Start_Page><End_Page>199</End_Page><Periodical>J Hosp Infect</Periodical><Volume>76</Volume><Issue>3</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20619933</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Quality Assurance &amp; Process Innovation Department, Academic Medical Center at the University of Amsterdam, The Netherlands</Address><ZZ_JournalStdAbbrev><f name="System">J Hosp Infect</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>10“Based on the available evidence from clinical trials, iodine is an effective antiseptic agent that shows neither the purported harmful effects nor a delay of wound-healing process, particularly in chronic and burn wounds. The antiseptic effect of iodine is not inferior to that of other (antiseptic) agents and does not impair wound healing.”YesNot reportedNot reportedXie et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Xie</Author><Year>2010</Year><RecNum>567850</RecNum><IDText>Percutaneous radiofrequency ablation for the treatment of early stage hepatocellular carcinoma: a health technology assessment</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567850</Ref_ID><Title_Primary>Percutaneous radiofrequency ablation for the treatment of early stage hepatocellular carcinoma: a health technology assessment</Title_Primary><Authors_Primary>Xie,X.</Authors_Primary><Authors_Primary>Dendukuri,N.</Authors_Primary><Authors_Primary>McGregor,M.</Authors_Primary><Date_Primary>2010/10</Date_Primary><Keywords>Aged</Keywords><Keywords>Carcinoma,Hepatocellular</Keywords><Keywords>*surgery</Keywords><Keywords>*Catheter Ablation</Keywords><Keywords>Female</Keywords><Keywords>Humans</Keywords><Keywords>Liver Neoplasms</Keywords><Keywords>Male</Keywords><Keywords>Middle Aged</Keywords><Keywords>*Technology Assessment,Biomedical</Keywords><Reprint>Not in File</Reprint><Start_Page>390</Start_Page><End_Page>397</End_Page><Periodical>Int J Technol Assess Health Care</Periodical><Volume>26</Volume><Issue>4</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/25/2011 for SP0106</User_Def_3><ISSN_ISBN>20923590</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Technology Assessment Unit, Royal Victoria Hospital, McGill University Health Center, 687 Pine Avenue West, R4.14, Montreal, Quebec, Canada H3A 1A1. shawn.xie@muhc.mcgill.ca</Address><ZZ_JournalStdAbbrev><f name="System">Int J Technol Assess Health Care</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>46“Continuing doubts on this issue can only be resolved by a substantial RCT. Meanwhile, for early stage HCC patients classified as Child-Pugh A, who despite a possibly higher recurrence rate, prefer the less invasive PRFA to open surgery with its attendant risks, there is sufficient evidence to justify such a choice. For those classified as Child-Pugh (B) it is possible that overall survival is equally good with PRFA, but the evidence is less certain.”NoNot reportedNot reportedYang et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Yang</Author><Year>2010</Year><RecNum>567554</RecNum><IDText>Efficacy and adverse effects of transdermal fentanyl and sustained-release oral morphine in treating moderate-severe cancer pain in Chinese population: a systematic review and meta-analysis</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567554</Ref_ID><Title_Primary>Efficacy and adverse effects of transdermal fentanyl and sustained-release oral morphine in treating moderate-severe cancer pain in Chinese population: a systematic review and meta-analysis</Title_Primary><Authors_Primary>Yang,Q.</Authors_Primary><Authors_Primary>Xie,D.R.</Authors_Primary><Authors_Primary>Jiang,Z.M.</Authors_Primary><Authors_Primary>Ma,W.</Authors_Primary><Authors_Primary>Zhang,Y.D.</Authors_Primary><Authors_Primary>Bi,Z.F.</Authors_Primary><Authors_Primary>Chen,D.L.</Authors_Primary><Date_Primary>2010</Date_Primary><Keywords>Administration,Oral</Keywords><Keywords>Analgesics,Opioid</Keywords><Keywords>administration &amp; dosage</Keywords><Keywords>*adverse effects</Keywords><Keywords>pharmacology</Keywords><Keywords>Cohort Studies</Keywords><Keywords>Fentanyl</Keywords><Keywords>administration &amp; dosage</Keywords><Keywords>*adverse effects</Keywords><Keywords>pharmacology</Keywords><Keywords>Humans</Keywords><Keywords>Morphine</Keywords><Keywords>administration &amp; dosage</Keywords><Keywords>*adverse effects</Keywords><Keywords>pharmacology</Keywords><Keywords>Neoplasms</Keywords><Keywords>*co</Keywords><Reprint>Not in File</Reprint><Start_Page>67</Start_Page><Periodical>J Exp Clin Cancer Res</Periodical><Volume>29</Volume><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/23/2011 for SP0106</User_Def_3><ISSN_ISBN>20529380</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Oncology, The Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 west Yanjiang Road, Guangzhou, Guangdong, 510120, China</Address><ZZ_JournalStdAbbrev><f name="System">J Exp Clin Cancer Res</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>1“Our study showed again that both transdermal fentanyl and oral morphine had the same efficacy in the treatment of moderate-severe cancer pain in Chinese population, but the former might have less adverse effects and better quality of life.”YesNot reported Not reportedAgarwal et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Agarwal</Author><Year>2010</Year><RecNum>567383</RecNum><IDText>Updated meta-analysis of septal alcohol ablation versus myectomy for hypertrophic cardiomyopathy</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567383</Ref_ID><Title_Primary>Updated meta-analysis of septal alcohol ablation versus myectomy for hypertrophic cardiomyopathy</Title_Primary><Authors_Primary>Agarwal,S.</Authors_Primary><Authors_Primary>Tuzcu,E.M.</Authors_Primary><Authors_Primary>Desai,M.Y.</Authors_Primary><Authors_Primary>Smedira,N.</Authors_Primary><Authors_Primary>Lever,H.M.</Authors_Primary><Authors_Primary>Lytle,B.W.</Authors_Primary><Authors_Primary>Kapadia,S.R.</Authors_Primary><Date_Primary>2010/2/23</Date_Primary><Keywords>Cardiomyopathy,Hypertrophic</Keywords><Keywords>*surgery</Keywords><Keywords>Catheter Ablation</Keywords><Keywords>*methods</Keywords><Keywords>Ethanol</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Female</Keywords><Keywords>Heart Septum</Keywords><Keywords>*surgery</Keywords><Keywords>Humans</Keywords><Keywords>Male</Keywords><Keywords>Treatment Outcome</Keywords><Reprint>Not in File</Reprint><Start_Page>823</Start_Page><End_Page>834</End_Page><Periodical>J Am Coll Cardiol</Periodical><Volume>55</Volume><Issue>8</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Jon Treadwell on 5/23/2011 for SP0106</User_Def_3><ISSN_ISBN>20170823</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Internal Medicine, Cleveland Clinic, Cleveland, Ohio, USA</Address><ZZ_JournalStdAbbrev><f name="System">J Am Coll Cardiol</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>47“[Septal ablation] does seem to show promise in treatment of [hypertrophic obstructive cardiomyopathy] owing to similar mortality rates as well as functional status compared with septal myectomy; however, the caveat is increased conduction abnormalities and a higher post-intervention [left ventricular outflow tract gradient.”YesNot reportedNot reportedAvouac et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Avouac</Author><Year>2010</Year><RecNum>567238</RecNum><IDText>Efficacy of joint lavage in knee osteoarthritis: meta-analysis of randomized controlled studies</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567238</Ref_ID><Title_Primary>Efficacy of joint lavage in knee osteoarthritis: meta-analysis of randomized controlled studies</Title_Primary><Authors_Primary>Avouac,J.</Authors_Primary><Authors_Primary>Vicaut,E.</Authors_Primary><Authors_Primary>Bardin,T.</Authors_Primary><Authors_Primary>Richette,P.</Authors_Primary><Date_Primary>2010/2</Date_Primary><Keywords>Aged</Keywords><Keywords>Combined Modality Therapy</Keywords><Keywords>Female</Keywords><Keywords>Glucocorticoids</Keywords><Keywords>administration &amp; dosage</Keywords><Keywords>Humans</Keywords><Keywords>Injections,Intra-Articular</Keywords><Keywords>Male</Keywords><Keywords>Middle Aged</Keywords><Keywords>Osteoarthritis,Knee</Keywords><Keywords>*therapy</Keywords><Keywords>Pain Measurement</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Therapeutic Irrigation</Keywords><Keywords>Treatment Outcome</Keywords><Reprint>Not in File</Reprint><Start_Page>334</Start_Page><End_Page>340</End_Page><Periodical>Rheumatology (Oxford)</Periodical><Volume>49</Volume><Issue>2</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>19955221</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Universite Paris 7, UFR Medicale, Assistance Publique-Hopitaux de Paris, Hopital Lariboisiere, Federation de Rhumatologie, Paris Cedex, France</Address><ZZ_JournalStdAbbrev><f name="System">Rheumatology (Oxford)</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>48“This meta-analysis of RCTs investigating joint lavage for knee OA suggests that at three months, (1) joint lavage alone [vs. placebo] does not provide significant improvement in pain or function and (2) the combination of joint lavage and IA steroid injection is no more efficacious that lavage alone.”NoNot reportedNot reportedChua et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Chua</Author><Year>2010</Year><RecNum>567041</RecNum><IDText>Systematic review of neoadjuvant transarterial chemoembolization for resectable hepatocellular carcinoma</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567041</Ref_ID><Title_Primary>Systematic review of neoadjuvant transarterial chemoembolization for resectable hepatocellular carcinoma</Title_Primary><Authors_Primary>Chua,T.C.</Authors_Primary><Authors_Primary>Liauw,W.</Authors_Primary><Authors_Primary>Saxena,A.</Authors_Primary><Authors_Primary>Chu,F.</Authors_Primary><Authors_Primary>Glenn,D.</Authors_Primary><Authors_Primary>Chai,A.</Authors_Primary><Authors_Primary>Morris,D.L.</Authors_Primary><Date_Primary>2010/2</Date_Primary><Keywords>Antineoplastic Agents</Keywords><Keywords>*administration &amp; dosage</Keywords><Keywords>Carcinoma,Hepatocellular</Keywords><Keywords>mortality</Keywords><Keywords>*therapy</Keywords><Keywords>*Chemoembolization,Therapeutic</Keywords><Keywords>Combined Modality Therapy</Keywords><Keywords>Hepatectomy</Keywords><Keywords>Humans</Keywords><Keywords>Liver</Keywords><Keywords>*surgery</Keywords><Keywords>Liver Neoplasms</Keywords><Keywords>mortality</Keywords><Keywords>*therapy</Keywords><Keywords>Randomized Controlled Trials as Topi</Keywords><Reprint>Not in File</Reprint><Start_Page>166</Start_Page><End_Page>174</End_Page><Periodical>Liver Int</Periodical><Volume>30</Volume><Issue>2</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/31/2011 for SP0106</User_Def_3><ISSN_ISBN>19912531</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Surgery, University of New South Wales, St George Hospital, Kogarah, Sydney, NSW, Australia</Address><ZZ_JournalStdAbbrev><f name="System">Liver Int</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>14“This systematic review presents the role of TACE in the setting of a resectable HCC. Current evidence indicates that there appears to be no DFS advantage despite its safety and feasibility. A well-designed prospective multi-institutional RCT, with a clearly defined protocol for concealed allocation, eligibility criteria, TACE intervention regimen and endpoints will be potentially meaningful.”NoNot reportedNot reportedDevaiah et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Devaiah</Author><Year>2010</Year><RecNum>567153</RecNum><IDText>Postmaneuver restrictions in benign paroxysmal positional vertigo: an individual patient data meta-analysis</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567153</Ref_ID><Title_Primary>Postmaneuver restrictions in benign paroxysmal positional vertigo: an individual patient data meta-analysis</Title_Primary><Authors_Primary>Devaiah,A.K.</Authors_Primary><Authors_Primary>Andreoli,S.</Authors_Primary><Date_Primary>2010/2</Date_Primary><Keywords>Algorithms</Keywords><Keywords>Controlled Clinical Trials as Topic</Keywords><Keywords>Evidence-Based Medicine</Keywords><Keywords>*Head Movements</Keywords><Keywords>Humans</Keywords><Keywords>Kinesiology,Applied</Keywords><Keywords>methods</Keywords><Keywords>*Semicircular Canals</Keywords><Keywords>physiopathology</Keywords><Keywords>Severity of Illness Index</Keywords><Keywords>Treatment Outcome</Keywords><Keywords>Vertigo</Keywords><Keywords>diagnosis</Keywords><Keywords>physiopathology</Keywords><Keywords>*rehabilitation</Keywords><Reprint>Not in File</Reprint><Start_Page>155</Start_Page><End_Page>159</End_Page><Periodical>Otolaryngol Head Neck Surg</Periodical><Volume>142</Volume><Issue>2</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20115966</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Otolaryngology-Head and Neck Surgery, Boston University School of Medicine, 88 East NewtonSt, D608 Collamore, Boston, MA 02118, USA. anand.devaiah@</Address><ZZ_JournalStdAbbrev><f name="System">Otolaryngol Head Neck Surg</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>49“The restrictions examined in controlled trials did not differ significantly in clinical outcomes, which suggest that restrictions do not appear to significantly affect the efficacy of benign paroxysmal positional vertigo.”NoNot reportedNot reportedLovemanet al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Loveman</Author><Year>2010</Year><RecNum>567292</RecNum><IDText>The clinical effectiveness and cost-effectiveness of topotecan for small cell lung cancer: a systematic review and economic evaluation</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567292</Ref_ID><Title_Primary>The clinical effectiveness and cost-effectiveness of topotecan for small cell lung cancer: a systematic review and economic evaluation</Title_Primary><Authors_Primary>Loveman,E.</Authors_Primary><Authors_Primary>Jones,J.</Authors_Primary><Authors_Primary>Hartwell,D.</Authors_Primary><Authors_Primary>Bird,A.</Authors_Primary><Authors_Primary>Harris,P.</Authors_Primary><Authors_Primary>Welch,K.</Authors_Primary><Authors_Primary>Clegg,A.</Authors_Primary><Date_Primary>2010/3</Date_Primary><Keywords>Adult</Keywords><Keywords>Antineoplastic Agents</Keywords><Keywords>adverse effects</Keywords><Keywords>economics</Keywords><Keywords>therapeutic use</Keywords><Keywords>Cost-Benefit Analysis</Keywords><Keywords>Humans</Keywords><Keywords>Lung Neoplasms</Keywords><Keywords>*drug therapy</Keywords><Keywords>economics</Keywords><Keywords>Small Cell Lung Carcinoma</Keywords><Keywords>*drug therapy</Keywords><Keywords>economics</Keywords><Keywords>Topotecan</Keywords><Keywords>adverse effects</Keywords><Keywords>*economics</Keywords><Keywords>*therapeutic use</Keywords><Reprint>Not in File</Reprint><Start_Page>1</Start_Page><End_Page>204</End_Page><Periodical>Health Technol Assess</Periodical><Volume>14</Volume><Issue>19</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 5/26/2011 for SP0106</User_Def_3><ISSN_ISBN>20356561</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Southampton Health Technology Assessments Centre, University of Southampton Science Park, Southampton, UK. hta@hta.ac.uk</Address><ZZ_JournalStdAbbrev><f name="System">Health Technol Assess</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>13“Topotecan appears to improve survival in people with SCLC when compared to BSC alone, is as effective as CAV but less effective than amrubicin in terms of response rates, and shows comparable rates of treatment toxicities and adverse events with CAV and amrubicin based on the data available. Oral and IV topotecan were not seen to be different from one another on survival or measures of response.”YesNot reportedNot reportedValachis et al. 2010 ADDIN REFMGR.CITE <Refman><Cite><Author>Valachis</Author><Year>2010</Year><RecNum>567118</RecNum><IDText>Fulvestrant in the treatment of advanced breast cancer: a systematic review and meta-analysis of randomized controlled trials</IDText><MDL Ref_Type="Journal"><Ref_Type>Journal</Ref_Type><Ref_ID>567118</Ref_ID><Title_Primary>Fulvestrant in the treatment of advanced breast cancer: a systematic review and meta-analysis of randomized controlled trials</Title_Primary><Authors_Primary>Valachis,A.</Authors_Primary><Authors_Primary>Mauri,D.</Authors_Primary><Authors_Primary>Polyzos,N.P.</Authors_Primary><Authors_Primary>Mavroudis,D.</Authors_Primary><Authors_Primary>Georgoulias,V.</Authors_Primary><Authors_Primary>Casazza,G.</Authors_Primary><Date_Primary>2010/3</Date_Primary><Keywords>Antineoplastic Agents,Hormonal</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Aromatase Inhibitors</Keywords><Keywords>*therapeutic use</Keywords><Keywords>Breast Neoplasms</Keywords><Keywords>*drug therapy</Keywords><Keywords>Estradiol</Keywords><Keywords>*analogs &amp; derivatives</Keywords><Keywords>therapeutic use</Keywords><Keywords>Female</Keywords><Keywords>Humans</Keywords><Keywords>Randomized Controlled Trials as Topic</Keywords><Keywords>Tamoxifen</Keywords><Keywords>*therapeutic use</Keywords><Reprint>Not in File</Reprint><Start_Page>220</Start_Page><End_Page>227</End_Page><Periodical>Crit Rev Oncol Hematol</Periodical><Volume>73</Volume><Issue>3</Issue><User_Def_2>MEDLINE - Ovid 5/6/2011</User_Def_2><User_Def_3>Given to Stacey Uhl on 6/1/2011 for SP0106</User_Def_3><ISSN_ISBN>19369092</ISSN_ISBN><Availability>Sharepoint , SP0106 , SP0106_May5 , SP0106_Methods2</Availability><Address>Department of Medical Oncology, University General Hospital of Heraklion, Greece</Address><ZZ_JournalStdAbbrev><f name="System">Crit Rev Oncol Hematol</f></ZZ_JournalStdAbbrev><ZZ_WorkformID>1</ZZ_WorkformID></MDL></Cite></Refman>50“Fulvestrant was similar to other hormonal agents with respect to efficacy measures, with good tolerability profile.”YesNot reportedNot reportedAEDAntiepileptic drugsBMSBare metal stentsBSCBest supportive careCAVCyclophosphamide, Adriamycin, and vincristineCBTCognitive behavioral therapyCOPDChronic obstructive pulmonary diseaseCYCCyclophosphamideDESDrug eluting stentsFESFunctional electrical stimulationGnRHGonadotropin-releasing hormoneHCCHepatocellular carcinomaHDRHigh-dose rateHESHydroxyethyl starchHRQoLHealth-related quality of lifeICBTIntracavity brachytherapyIFCInterferential current therapyIVIntravenousLDRLow-dose rateMDDMajor depressive disorderMDRMonotherapy drug regimenMMFMycophenolate mofetilMTAMineral trioxide aggregateOSOverall survivalPBIPartial breast irradiationPCAPatient-controlled analgesiaPCIPercutaneous interventionPRFAPercutaneous radiofrequency ablationRCTRandomized controlled trialRFARadiofrequency ablationRFSRelapse-free survivalRVORetinal vein occlusionSCLCSmall cell lung cancersmGPIssmall-molecule glycoprotein IIb/IIIa receptor inhibitorsSNRISerotonin norepinephrine reuptake inhibitorSSRISelective serotonin reuptake inhibitorSTEMIST-segment elevation myocardial infarctionSVGSaphenous vein graftTACETransarterial chemoembolizationTLRTarget lesion revascularizationTVRTarget vessel revascularizationVATVideo-assisted thoracoscopic surgeryVO2Peak oxygenWBRTWhole breast irradiation ................
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