Steroid-free SPIRIVA RESPIMAT can help full 24 hours Get more ...

SPIRIVA RESPIMAT, 1.25 mcg, is a long-term, once-daily, prescription maintenance treatment of asthma for people 6 years and older. SPIRIVA RESPIMAT is not a treatment for sudden asthma symptoms.

Even with daily maintenance medication

IS ASTHMA HOLDING YOU BACK?

Steroid-free SPIRIVA RESPIMAT can help loosen the grip of asthma for a full 24 hours

IMPORTANT SAFETY INFORMATION

Do not use SPIRIVA? RESPIMAT? (tiotropium bromide) Inhalation Spray if you are allergic to tiotropium, ipratropium, atropine or similar drugs, or any ingredient in this medicine. SPIRIVA RESPIMAT is not a rescue medicine and should not be used for treating sudden breathing problems. Your doctor may give you other medicine to use for sudden breathing problems. Please see complete Important Safety Information on pages 14-15. Click here for full Prescribing Information, including Instructions for Use.

Does this sound like you?

Short of breath

Tightness in your chest

Wheezing

Use a rescue inhaler more than twice a week

Many people with asthma continue to experience symptoms even when taking daily maintenance treatment. Your risk for an asthma attack is greatest when asthma is not controlled. You may miss work, overuse your rescue inhaler, or end up in the hospital due to asthma. Why wait?

Talk to your doctor about SPIRIVA RESPIMAT today.

IMPORTANT SAFETY INFORMATION (continued)

SPIRIVA RESPIMAT can cause allergic reactions. Symptoms can include raised red patches on your skin (hives), itching, rash and/or swelling of the lips, tongue, or throat that may cause di culty in breathing or swallowing. If you have any of these symptoms, stop taking the medicine and seek emergency medical care.

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You can breathe better

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Please see complete Important Safety Information on pages 14-15. Click here for full Prescribing Information, including Instructions for Use.

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GLUE AREA

Get more out of every breath

SPIRIVA RESPIMAT delivers medicine in a steroid-free mist that can improve your breathing. It works with daily maintenance medications to help you:

Breathe better for a full 24 hours

Control asthma without taking additional inhaled steroids

Cut the risk of asthma attacks in adults*

*An asthma attack (exacerbation) was defined as an increase in asthma symptoms (shortness of breath, cough, wheezing, or chest tightness), or trouble breathing lasting for 2 or more consecutive days, requiring additional treatment.

IMPORTANT SAFETY INFORMATION (continued)

SPIRIVA RESPIMAT can cause your breathing to suddenly get worse (bronchospasm). If this happens, use your rescue inhaler, stop taking SPIRIVA RESPIMAT, and call your doctor right away or seek emergency medical care. 4

Open your airways with SPIRIVA RESPIMAT

Please see complete Important Safety Information on pages 14-15. Click here for full Prescribing Information, including Instructions for Use.

SPIRIVA RESPIMAT makes a difference

SPIRIVA RESPIMAT opens asthma-constricted airways for a full 24 hours. As a result, more air gets where it needs to go. And that means you can get more out of every breath.

IMPORTANT SAFETY INFORMATION (continued)

SPIRIVA RESPIMAT can increase the pressure in your eyes (acute narrow-angle glaucoma), which can cause the following symptoms: eye pain, blurred vision, seeing halos or colored images along with red eyes. If you have any of these symptoms, stop taking your medicine and call your doctor right away. 6

Maintenance therapy may not be enough

Asthma makes it di cult to breathe in two ways: inflammation and constricting the airways.

Treating Inflammation

Inhaled steroids help reduce inflammation and are important for relieving asthma symptoms.

Opening Airways

Your doctor may also prescribe medications that are meant to prevent airway constriction. If these daily maintenance treatments fail to control your asthma symptoms, there are two options to consider: increase your dose of inhaled steroids or talk to your doctor about adding steroid-free SPIRIVA RESPIMAT.

Expand Your Airways

SPIRIVA RESPIMAT relaxes the tiny muscles in your airways so you can breathe better. If you're taking a daily maintenance treatment already, SPIRIVA RESPIMAT can open your airways even further--and keep them open for 24 hours.

Steroid-free SPIRIVA RESPIMAT has a demonstrated safety profile

Please see complete Important Safety Information on pages 14-15. Click here for full Prescribing Information, including Instructions for Use.

Demonstrated safety

In clinical studies of almost 4500 children and adults with asthma, steroid-free SPIRIVA RESPIMAT was shown to be safe and e ective for patients as young as 6 years of age.

SPIRIVA RESPIMAT fits into your daily routine and it's steroid-free

IMPORTANT SAFETY INFORMATION (continued)

Dizziness and blurred vision may occur with SPIRIVA RESPIMAT. If you experience these symptoms, use caution when engaging in activities such as driving a car, or operating appliances or machinery.

SPIRIVA RESPIMAT can cause new or worsened urinary retention. Symptoms of blockage in your bladder and/or enlarged prostate may include di culty passing urine and/or painful urination. If you have any of these symptoms, stop taking your medicine and call your doctor right away.

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Please see complete Important Safety Information on pages 14-15. Click here for full Prescribing Information, including Instructions for Use.

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