Evidence-based Guideline: Diagnosis and Treatment of Limb ...
Prominent muscle cramps (spontaneous, postexercise, or myalgias) were noted in most patients.e120-e122 In 3 studies, distal hand weakness and atrophy was noted in 9/23 patients.e121,e122,e132 In one series, 3 of 10 patients presented with toe walking but did not have distal leg weakness.e121 Rippling muscle disease was the sole manifestation of ... ................
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