By 10-11wk age, all PKD2 WS25/- mice have bilateral renal ...

In this murine model, bilateral cyst formation occurs in 100% of animals by 10-11 wk age [14]. As in human ADPKD, formation of kidney cysts in this model is associated with renal failure and early death [14]. But to our experience and according to literatures, the decline of renal function in this mouse line is … ................
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