Indian Council of Medical Research | Government of India
ICMR-Task-Force on ‘OMICS’ in Health & Disease:
In recent years, Systems approach is gaining great importance towards understanding Human Biology both in health and disease conditions. This discipline integrates Genomic, Proteomics, Metabolomics and Lipidomics Sciences to get a comprehensive picture/profile of cellular and organismal biology. Significant advancement has been made in Genomics during the last 15 years while Proteomics, Metabolomics and Lipidomics have gained considerable momentum in the past 5 to 8 years. Over the last decade ICMR has also supported a large number of PI initiated projects on Genomics of human diseases. Now it is becoming clear that the integration of information from different –omics studies can provide scientists and clinicians with a powerful tool to understand the different processes involved in disease development and progression. It provides great opportunity and hope to identify biomarkers specific for different cellular processes or disease state along with those indicating efficacious therapeutic intervention. This call for proposal is primarily for Mission mode projects addressing an integrated approach of Genomics (encompassing transcriptomics and epigenomics), Proteomics, Metabolomics and Lipidomics, to gain better understanding of diseases of interest as mentioned below.
Mission Mode Projects are invited in the following areas:
• Airway diseases
• Neglected tropical diseases
• Inborn metabolic disorders
• Neonatal stunting
• Life style diseases (Obesity, Non-alcoholic fatty liver disease and cardio-metabolic disease)
Concept proposals for the multi-centric projects with specific objectives and definite scientific questions on the above disorder / diseases should be submitted online by 8th February 2021. These projects have to be carried out by integrating/networking expertise available in multiple institutions utilizing existing facilities. However, smaller projects with potential to deliver are also encouraged.
Criteria for application:
The proposals should adhere to the focus areas and disease areas described. The scientific team should have demonstrable expertise in the areas of disease focus. Collaborations between institutes and between research and clinical teams are encouraged. Proposals must be written in the English language and clearly titled in the ICMR format. Project descriptions and style should conform to ICMR guidelines and have all requisite approvals and permissions required.
How to apply:
Duration of the research proposals should be up to three years. All projects involving research on human beings/animals must be cleared by the Human ethics committee/Animal ethics committee of the respective institute. Interested applicants are required to email the concept proposal to omics.icmr@. The format for preparing the concept proposal is given below and is also available on ICMR website icmr.nic.in. Our advisory panel will review the submitted proposals and shortlisted applicants will be asked to submit the detailed proposal.
Timeline:
• Launch of call for concept proposal on ICMR website: 8th January 2021 ends on 8th February, 2021 at 5:00 PM
• Scrutiny of concept and results by 31th March 2021
• Full project submission ends: 15th May, 2021
• Announcement of Successful Projects: 15th June, 2021
Eligibility:
All scientific institutions, including Universities, DSIR certified institutes and laboratories are eligible.
Review process:
The applications will be screened for technical correctness. Thereafter, each proposal will be reviewed for transformative and translational potential of the project, its scientific quality and originality, adequate project plan (sample quality, experimental design, statistics, data analysis and management) and budget. Clarity in experimental design, demonstration of prior experience/preliminary data, achievable milestones and timelines and potential for clinical translation also carries weightage.
FURTHER INFORMATION CONTACTS
Program Coordinator:
Dr. Geeta Jotwani
Scientist ‘F’
Division of Basic Medical Scientist
Indian Council of Medical Research
V. Ramalingaswami Bhavan
Ansari Nagar, New Delhi- 110029
Email: jotwanig.hq@.in
Telephone: 011-26589272
PABX: 011-26588895 (Extn-285)
CONCEPT PROPOSAL SUBMISSION FORMAT
Applicants are required to Email the concept proposal to omics.icmr@ in PDF format. The applicants should also mention the name of the thematic area in the subject of the Email. Concept Proposal must to be prepared under the following sub-headings (mandatory) and exceeding the word limit will lead to disqualification.
1. Thematic Area: The applicants must mention the thematic area under which they wish to apply.
2. Title of the proposed research project: Should be concise and informative.
3. Rationale (up to 250 words): Describe the current knowledge available on the subject, critical gaps in knowledge and the national relevance of the research question which this project aims to address. Also, mention the preliminary work done by the applicant, if any.
4. Novelty/Innovation (up to 100 words): Describe how the proposal challenges and seeks to shift the current research/knowledge/clinical practice paradigms by utilizing novel theoretical concepts, methodologies, instrumentation or interventions.
5. Project description (up to 600 words): Describe the study setting, study design, sampling strategy, sample size, research methodology and outcomes measures. Also, mention expected timelines, total budget, name and designation of co-investigators and intra and inter institutional collaborations, if any.
6. Strength of PI: Describe academic qualifications, employment details, previous experience of handling research projects (past and ongoing) and the scientific contributions made from these projects. Enumerate 10 relevant publications (in Vancouver style).
7. Institutional support (up to 200 words): Mention the institutional support in terms of basic infrastructure, departments and laboratories with equipment required for the proposed research work.
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